Journal of The Egyptian Society of Nephrology and Transplantation最新文献_第7页

A case of factitious disorder presenting as acute kidney injury 人为障碍表现为急性肾损伤1例

Journal of The Egyptian Society of Nephrology and Transplantation Pub Date : 2021-04-01 DOI: 10.4103/jesnt.jesnt_29_20

A. Gopal, G. Jacob, G. Noble, Kumar Sajeev, V. Nair, Jayaprakash Puthiyapurayil

引用次数: 0

Biomarkers of myocardial injury in lupus nephritis 狼疮性肾炎心肌损伤的生物标志物

Journal of The Egyptian Society of Nephrology and Transplantation Pub Date : 2021-04-01 DOI: 10.4103/jesnt.jesnt_27_20

Mohammed Ibrahim, El Metwally EIshahawy, A. Mahmoud, Rehab Nasr, A. Mansour

{"title":"Biomarkers of myocardial injury in lupus nephritis","authors":"Mohammed Ibrahim, El Metwally EIshahawy, A. Mahmoud, Rehab Nasr, A. Mansour","doi":"10.4103/jesnt.jesnt_27_20","DOIUrl":"https://doi.org/10.4103/jesnt.jesnt_27_20","url":null,"abstract":"Background Cardiovascular disease (CVD) is the main cause of death in patients with systemic lupus erythematosus (SLE) and lupus nephritis (LN). This study aimed to evaluate the prevalence of myocardial injury among patients with SLE without nephritis and patients with LN, determine whether serum high-sensitivity cardiac troponin T and creatine phosphokinase-MB (CKMB) might help to identify patients with LN at risk for CVD, and identify LN as a risk factor for myocardial injury. Patients and methods This study was conducted on 50 patients (30 patients with LN and 20 patients with SLE without nephritis). The SLE disease activity index (SLEDAI) and Systemic Lupus International Collaborating Clinics Damage Index (SLICC/DI) were assessed. Laboratory investigations, cardiac enzymes (Hs-TnT and CKMB), and transthoracic echocardiography were performed. Results The results demonstrated a higher prevalence of CVD in patients with LN. A total of 28 patients with LN (93.3%) vs 10 patients with SLE (50%) had detectable high-sensitivity troponin (Hs-TnT) levels, with a mean 29.77±18.22 vs 7.2±6.21 ng/l, respectively. The mean value of CKMB was higher in patients with LN than patients with SLE (23.9±18.6 vs 14.8±9.4 μg/l, respectively). Multilinear regression analysis for Hs-TnT revealed that low estimated glomerular filtration rate, high urinary albumin-to-creatinine ratio, low ejection fraction, and different ECHO diameters were the most statistically significant predictors of troponin elevation, with a P value less than 0.05. The strongest renal predictors of CKMB were estimated glomerular filtration rate and proteinuria, with a P value less than 0.05. Conclusion CVD is more in patients with LN than patients with SLE. Hs-TnT levels is a signature of subclinical cardiac disease, which could be used to identify at-risk individuals. CKMB and echocardiography lack adequate sensitivity for the diagnosis of myocardial injury in patients with LN.","PeriodicalId":285751,"journal":{"name":"Journal of The Egyptian Society of Nephrology and Transplantation","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126189461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Study of the effect of early and late acute rejection episodes on renal graft survival 早期和晚期急性排斥反应对移植肾存活影响的研究

Journal of The Egyptian Society of Nephrology and Transplantation Pub Date : 2021-04-01 DOI: 10.4103/jesnt.jesnt_28_20

A. Ragheb, M. Kora, Yassin Hassan, H. Kasem

{"title":"Study of the effect of early and late acute rejection episodes on renal graft survival","authors":"A. Ragheb, M. Kora, Yassin Hassan, H. Kasem","doi":"10.4103/jesnt.jesnt_28_20","DOIUrl":"https://doi.org/10.4103/jesnt.jesnt_28_20","url":null,"abstract":"Background It has been demonstrated that acute rejection (AR) episodes are major risk factors of renal allograft loss. Still the impact of early acute rejection (EAR) on long-term graft survival is debated. The aim of this study was to study the impact of early acute rejection (EAR) and late acute rejection (LAR) on renal allograft survival. Patients and methods In this retrospective study we investigated the timing and frequency of AR episodes in 120 kidney transplant recipients for a 3-years period. Patients were divided into three groups; Group I: No acute rejection (No-AR), Group II: Early acute rejection (EAR), and Group III: Late acute rejection (LAR). The graft survivals in the three groups and the associated risk factors were analyzed. Results Of the 120 recipients one patient died (0.08%) and 14 grafts were lost (11.6%). The graft survival durations were 35.2, 23.6 and 27.2 months and the 3-years survival rates were 93%, 63.3% and 66.7% in the three groups respectively. The graft survival durations and rates were significantly higher in group I compared to groups II and III with no significant differences between the last two groups. Conclusion Both EAR and LAR have deleterious effects on graft survival following kidney transplantation.","PeriodicalId":285751,"journal":{"name":"Journal of The Egyptian Society of Nephrology and Transplantation","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115318061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Current clinical situation of hemodialysis patients in nephrology center, Benghazi, Libya 利比亚班加西肾内科中心血液透析患者临床现状分析

Journal of The Egyptian Society of Nephrology and Transplantation Pub Date : 2021-01-01 DOI: 10.4103/jesnt.jesnt_8_20

Khaled D. Alsaeiti, Mohamed Hamedh, Sabah Albarasi, Marwa Alagoory, Yosser Isawi, Sanad Benali, Muftah Elsaeiti

{"title":"Current clinical situation of hemodialysis patients in nephrology center, Benghazi, Libya","authors":"Khaled D. Alsaeiti, Mohamed Hamedh, Sabah Albarasi, Marwa Alagoory, Yosser Isawi, Sanad Benali, Muftah Elsaeiti","doi":"10.4103/jesnt.jesnt_8_20","DOIUrl":"https://doi.org/10.4103/jesnt.jesnt_8_20","url":null,"abstract":"Background Dialysis adequacy is an important and effective factor in reducing mortality and morbidity among patients with end-stage kidney disease. This study aims to assess the current clinical situation of hemodialysis (HD) patients, to monitor the established quality-of-care indicators, and to identify the unachieved quality-of-care goals. Patients and methods This is an observational study in which all patients underwent chronic HD program (>1 year) at the nephrology center in Benghazi, Libya. It was conducted between January and June 2018. Mean levels were collected for the following indicators: hemoglobin, dialysis dose, serum calcium and phosphorus, parathyroid hormone, systolic and diastolic blood pressure, interdialytic hypotension, and vascular access. Results A total of 292 dialysis patients were reviewed and followed over a 6-month period. Overall, 170 (58.2%) were males and 122 (41.8%) were females. Mean age was 51.1±14 years. Hypertension was the most common cause of end-stage kidney disease in 76 (26.0%) patients followed by diabetes mellitus in 32 (11.0%) patients. Our patients failed to achieve adequate HD, as laboratory value results were as follows: mean hemoglobin level less than 10 g/dl in 61% of patients, serum Ca+2 was less than 8.4 mg/dl in 48.6%, serum PhO4 was more than 5.5 mg/dl in 50%, and serum parathyroid hormone was more than 300 ng/dl in 60.3%. Conclusion Dialysis insufficiency was seen in a significant percent of patients in this study. More extensive research studies for finding the causes of low dialysis quality are suggested.","PeriodicalId":285751,"journal":{"name":"Journal of The Egyptian Society of Nephrology and Transplantation","volume":"342 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124230620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Anti-glomerular basement membrane disease: a case series from a single center in Western India 抗肾小球基底膜病:来自印度西部单一中心的病例系列

Journal of The Egyptian Society of Nephrology and Transplantation Pub Date : 2021-01-01 DOI: 10.4103/jesnt.jesnt_3_19

M. Parikh, A. Konnur, U. Hegde, S. Gang, H. Patel, J. Patel

{"title":"Anti-glomerular basement membrane disease: a case series from a single center in Western India","authors":"M. Parikh, A. Konnur, U. Hegde, S. Gang, H. Patel, J. Patel","doi":"10.4103/jesnt.jesnt_3_19","DOIUrl":"https://doi.org/10.4103/jesnt.jesnt_3_19","url":null,"abstract":"Background Anti-glomerular basement membrane (GBM) disease is an autoimmune disorder defined by the presence of autoantibody directed against α3 chain of type IV collagen. It is clinically characterized by rapidly progressive glomerulonephritis and lung hemorrhage. Patients and methods A retrospective study of 25 patients with anti-GBM disease, who were diagnosed and followed up at our institute from January 2011 to December 2017, was undertaken. Most patients presented with hypertension (76%), oliguria (80%), and dialysis-dependent renal failure (96%). Hemoptysis was seen in only one-third (28%) of patients. Diffuse glomerulosclerosis with crescents was the most common renal histopathology (60%) seen. Results Of all patients who were able to get adequate treatment in the form of plasmapheresis (56%) and immunosuppression (100%), only one (4%) patient recovered. Conclusion The majority of our patients with anti-GBM presented late in their clinical course of the disease, with advanced renal failure and irreversible lesion on kidney biopsy. High index of suspicion, early diagnosis, and aggressive management may improve the outcome of these patients.","PeriodicalId":285751,"journal":{"name":"Journal of The Egyptian Society of Nephrology and Transplantation","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127735289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

OBITUARY: PROFESSOR SHEASHAA (1968 – 2020)

Journal of The Egyptian Society of Nephrology and Transplantation Pub Date : 2021-01-01 DOI: 10.4103/1110-9165.308522

引用次数: 0

Management of the failing renal allograft: an updated summary of the guidelines 同种异体肾移植失败的处理:指南的更新摘要

Journal of The Egyptian Society of Nephrology and Transplantation Pub Date : 2021-01-01 DOI: 10.4103/jesnt.jesnt_10_20

N. Gunawansa, Ajay K. Sharma, A. Halawa

引用次数: 0

Recirculation and adequacy of dialysis in end stage renal disease patients on regular hemodialysis at Menoufia university hospitals 梅努菲亚大学附属医院定期血液透析的终末期肾病患者透析的再循环和充分性

Journal of The Egyptian Society of Nephrology and Transplantation Pub Date : 2021-01-01 DOI: 10.4103/jesnt.jesnt_20_20

Sara Abd El-Sattar, A. El-Arbagy, Y. Yassein, H. Kasem

{"title":"Recirculation and adequacy of dialysis in end stage renal disease patients on regular hemodialysis at Menoufia university hospitals","authors":"Sara Abd El-Sattar, A. El-Arbagy, Y. Yassein, H. Kasem","doi":"10.4103/jesnt.jesnt_20_20","DOIUrl":"https://doi.org/10.4103/jesnt.jesnt_20_20","url":null,"abstract":"Background Early detection of vascular access complication prevents more severe conditions and reduces hospitalization periods of patients on regular hemodialysis (HD). Access recirculation (AR) is one of the tools for early evaluation of arteriovenous fistula (AVF) complication for early intervention. The aim of our study was to evaluate the AV AR as a risk factor for inadequate HD in patients with end-stage renal disease in Menoufia university hospitals. Patients and methods This is a cross-sectional study that included 300 patients on regular HD sessions at four centers at Menoufia university hospitals. All patients were subjected to detailed history taking, clinical examination, laboratory investigation, and measurement of recirculation by urea-based method. Results This study included 300 patients on regular HD. It showed that 51.7% presented with aneurysm, whereas the infected AV access was presented in 6% of patients. AR was found in 17.7% of patients, being more frequent in patients with the left brachiocephalic AVF (37.7%), and it showed highly significant relation with duration of dialysis and duration of AVF creation. The risk factors for recirculation were the distance between arterial and venous needle sites, puncture site aneurysm, and stenosis. There were negative correlations between AR and both urea reduction ratio and KT/V and positive with both serum potassium and parathyroid hormone level. Conclusion AR in our unit was associated mainly with stenosis, aneurysm, and improper needle puncture sites, so screening for recirculation may be used as a surveillance technique for the early detection of AVF in concomitant with regular training of dialysis staff in cannulation of the AVF.","PeriodicalId":285751,"journal":{"name":"Journal of The Egyptian Society of Nephrology and Transplantation","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129228655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Study of the relation between arterial oxygen saturation and intradialytic hypertension in regular hemodialysis patients 常规血液透析患者血氧饱和度与分析性高血压关系的研究

Journal of The Egyptian Society of Nephrology and Transplantation Pub Date : 2021-01-01 DOI: 10.4103/jesnt.jesnt_25_20

S. Khamis, Khaled El Zorkany, Wassam El-Shafey, Sara Kasher, A. Ragheb

{"title":"Study of the relation between arterial oxygen saturation and intradialytic hypertension in regular hemodialysis patients","authors":"S. Khamis, Khaled El Zorkany, Wassam El-Shafey, Sara Kasher, A. Ragheb","doi":"10.4103/jesnt.jesnt_25_20","DOIUrl":"https://doi.org/10.4103/jesnt.jesnt_25_20","url":null,"abstract":"Background Patients with IDHTN have an increased risk for hospitalizations and mortality. The pathogenesis of IDHTN is not well understood. Hypoxemia is thought to stimulate the blood pressure (BP) elevation. The aim of this work was to study the changes of the arterial oxygen saturation (SaO2) during hemodialysis (HD) and their relations to intradialytic hypertension (IDHTN). Patients and methods This is a prospective observational study that analyzed SaO2 and BP changes during HD sessions in 75 regular HD patients over 6 months. Patients were divided into two groups: group A included patients without intradialytic hypertension (non-IDHTN) and group B included patients with persistent IDHTN group. Results Group B patients had significantly lower predialysis, intradialytic, and postdialysis SaO2 levels compared with group A (P<0.001). Group B patients also showed a significant drop in intradialytic SaO2 compared to group A (P<0.001). There were significant negative correlations between the predialysis, intradialytic, and postdialysis SaO2 and intradialytic systolic blood pressure elevation (P<0.001). It was found that the reduction of the predialysis and intradialytic SaO2 less than 92.5 and 90.5%, respectively, could be predictors of intradialytic systolic blood pressure increase (P<0.001). Conclusion Decreased SaO2 before and during HD sessions may be involved in the induction of IDHTN.","PeriodicalId":285751,"journal":{"name":"Journal of The Egyptian Society of Nephrology and Transplantation","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130629872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Message From Heaven; Evolution of tele-education in nephrology in Egypt before and during COVID-19 era: a journey of 15 years of experience 来自天堂的信息;2019冠状病毒病之前和期间埃及肾脏学远程教育的演变:15年经验之旅

Journal of The Egyptian Society of Nephrology and Transplantation Pub Date : 2021-01-01 DOI: 10.4103/jesnt.jesnt_43_20

A. Halawa

引用次数: 0