European Conference on Biomedical Optics最新文献_第3页

Plano-concave optical sensor for transcranial photoacoustic measurements 用于经颅光声测量的平凹光学传感器

European Conference on Biomedical Optics Pub Date : 2023-08-11 DOI: 10.1117/12.2675593

T. Kirchner, C. Villringer, Marko Gutke, J. Laufer

{"title":"Plano-concave optical sensor for transcranial photoacoustic measurements","authors":"T. Kirchner, C. Villringer, Marko Gutke, J. Laufer","doi":"10.1117/12.2675593","DOIUrl":"https://doi.org/10.1117/12.2675593","url":null,"abstract":"Biomedical photoacoustics is usually used to image absorption-based contrast in soft tissues up to depths of several centimeters and with sub-millimeter resolution. By contrast, measuring Photoacoustic (PA) signals through hard bone tissue shows severe signal degradation due to aberration and high attenuation of high frequency acoustic signal components. This is particularly noticeable when measuring through thicker, human, skull bone. Which is the main reason why transcranial PA imaging in humans has so far proved challenging to implement. To tackle this challenge, we developed an optical resonator sensor based on a previous planar-concave design. This sensor was found to be highly suitable for measuring the low-pressure amplitude and low acoustic frequency signals that are transmitted through human cranial bone. A plano-concave optical resonator sensor was fabricated to provide high sensitivity in the acoustic frequency range of DC to around 2 MHz, a low noise equivalent pressure and a small active element size enabling it to significantly outperform conventional piezoelectric transducers when measuring PA waves transmitted through ex vivo human cranial bones.","PeriodicalId":278089,"journal":{"name":"European Conference on Biomedical Optics","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114957787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Improvement of image characteristics for 3D CBCT in dental medicine using OCT 利用OCT改进牙科医学三维CBCT图像特征

European Conference on Biomedical Optics Pub Date : 2023-08-11 DOI: 10.1117/12.2664998

Ralph Alexandru Erdelyi, Virgil-Florin Duma

{"title":"Improvement of image characteristics for 3D CBCT in dental medicine using OCT","authors":"Ralph Alexandru Erdelyi, Virgil-Florin Duma","doi":"10.1117/12.2664998","DOIUrl":"https://doi.org/10.1117/12.2664998","url":null,"abstract":"X-rays imaging is the gold standard in dental medicine for diagnosis and treatment evaluation and monitoring. We have explored the possible synergy of different types of dental radiographies with another imaging technique, Optical Coherence Tomography (OCT). With regard to the former, the latter offers higher resolution and non-invasive imaging of the tissue structure with no radiation exposure. However, OCT has much lower penetration depth. This trade-off between various characteristics imposes one or the other of these two techniques, or in some cases both of them for different medical investigations. Thus, we have explored the integration of these two imaging modalities, which can provide improved visualization of the tissue structure, enhance diagnostic accuracy, and reduce patient radiation dose. Also, we demonstrated that OCT can successfully serve as an optimization technique for various types of radiographies. This report is focused on such optimizations performed for dental 3D Cone-Beam Computed Tomography (CBCT). The use of CBCT X-ray units in dentistry imaging has revolutionized the way images are captured and processed. However, these units often suffer from low image quality, limited tissue visualization, and exposure to ionizing radiation. While CBCT images are useful for dental diagnosis and planning, they can be limited by poor tissue contrast and a lack of information about the internal structure of the tissues being imaged. We present how the integration of OCT in the process of optimization of CBCT X-ray units allows for real-time imaging of the tissue with improved accuracy and resolution. This combination provides dentists with detailed images of the tooth, jaw, and surrounding tissues, which enables better diagnosis and treatment planning. In conclusion, the optimization of CBCT X-ray units with OCT can be a step forward in the field of medical imaging. This combination can provide a more comprehensive, accurate, and non-invasive approach to tissue imaging that benefits both patients and healthcare professionals.","PeriodicalId":278089,"journal":{"name":"European Conference on Biomedical Optics","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123439392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Novel calibration method for optical coherence tomography instruments using multiple spectrometers 多光谱仪光学相干层析成像仪器标定新方法

European Conference on Biomedical Optics Pub Date : 2023-08-11 DOI: 10.1117/12.2670909

Gianni Nteroli, Lucy Abbott, R. D. Engelsholm, P. Montague, A. Podoleanu, A. Bradu

{"title":"Novel calibration method for optical coherence tomography instruments using multiple spectrometers","authors":"Gianni Nteroli, Lucy Abbott, R. D. Engelsholm, P. Montague, A. Podoleanu, A. Bradu","doi":"10.1117/12.2670909","DOIUrl":"https://doi.org/10.1117/12.2670909","url":null,"abstract":"In this report, a novel calibration method is introduced, which can be used in camera-based Optical Coherence Tomography (OCT) instruments employing several spectrometers. To ensure that all spectrometers are calibrated, i.e. they sense the same spectral range and the distribution of the optical frequencies across the pixels of the cameras is the same, a hybrid method was used involving (i) a hardware procedure for an initial estimation of the edges of the spectra and (ii) a numerical Monte-Carlo based technique. The utility of such a procedure is demonstrated in an OCT system using a Balance-Detection (BD) scheme. The OCT system employs a single transmission diffraction grating and is driven by a supercontinuum source operating in the visible spectral range. Spectral alignment is paramount in producing high-sensitivity images free of artefacts. To ensure correct calibration, and speed up the calibration procedure, the Master-Slave (MS) technique of generating axial reflectivity profiles is employed. Preliminary results show an improvement of the signal of ~ 3dB and a mitigation of the background noise of over 5 dB.","PeriodicalId":278089,"journal":{"name":"European Conference on Biomedical Optics","volume":"76 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123604192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Advanced FFT-based contrast approach for MHz optical coherence elastography 基于fft的MHz光学相干弹性成像对比度改进方法

European Conference on Biomedical Optics Pub Date : 2023-08-11 DOI: 10.1117/12.2670957

Sazgar Burhan, Nicolas Detrez, M. Göb, M. Bonsanto, Ralf Brinkmann, R. Huber

引用次数: 0

Portable hand-held optoacoustic system for localizing blood vessels at intermediate depths 用于定位中深度血管的便携式手持光声系统

European Conference on Biomedical Optics Pub Date : 2023-08-11 DOI: 10.1117/12.2669581

Zohar Or, Ahiad R. Levi, Y. Hazan, A. Rosenthal

{"title":"Portable hand-held optoacoustic system for localizing blood vessels at intermediate depths","authors":"Zohar Or, Ahiad R. Levi, Y. Hazan, A. Rosenthal","doi":"10.1117/12.2669581","DOIUrl":"https://doi.org/10.1117/12.2669581","url":null,"abstract":"The rapid localization of blood vessels in patients is important in various clinical applications, such as catheterization procedures. While optical techniques, including visual inspection, are limited in their effectiveness at depths below 1 mm, ultrasound and optoacoustic tomography can be used at deeper depths but require a spacer between the tissue and transducer to visualize superficial structures. In this work, we introduce a portable hand-held optoacoustic system that is capable of localizing blood vessels from the point of contact to a depth of 1 cm without the need for a spacer. The probe features a flat, lens-free ultrasound array which enables a largely depth independent response, though at the cost of reduced elevational resolution. In contrast to lens-based probes, where acoustic signals from outside the focal region are distorted, the amplitude of the signal from our probe only varies with depth, resulting in an imaging quality that is largely depth-independent within the imaged region. Additionally, to facilitate miniaturization, dark-field illumination is used, whereby light scattering from the tissue is exploited to homogenize the sensitivity field.","PeriodicalId":278089,"journal":{"name":"European Conference on Biomedical Optics","volume":"146 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125863597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Human-derived tumor-spheroid-based anti-cancer drugs testing using dynamic optical coherence tomography 基于人源性肿瘤球体的抗癌药物动态光学相干断层扫描测试

European Conference on Biomedical Optics Pub Date : 2023-08-11 DOI: 10.1117/12.2670856

I. Abd El-Sadek, R. Morishita, T. Mori, S. Makita, P. Mukherjee, S. Matsusaka, Y. Yasuno

引用次数: 0

Spatio-temporal optical coherence tomography (STOC-T) for high-resolution structural and functional imaging of the human and mouse retina in vivo 时空光学相干断层扫描(stock -t)用于人体和小鼠视网膜的高分辨率结构和功能成像

European Conference on Biomedical Optics Pub Date : 2023-08-11 DOI: 10.1117/12.2670806

D. Borycki, P. Węgrzyn, E. Auksorius, Wiktor M. Kulesza, S. Tomczewski, K. Liżewski, A. Curatolo, M. Wojtkowski

引用次数: 0

Towards automatic identification of middle ear structures in endoscopic OCT 内窥镜OCT中耳结构自动识别的研究

European Conference on Biomedical Optics Pub Date : 2023-08-11 DOI: 10.1117/12.2671026

Jonas Golde, J. Morgenstern, Peng Liu, S. Ossmann, L. Kirsten, S. Steuer, S. Speidel, E. Koch, S. Bodenstedt, Marcus Neudert

引用次数: 0

Accurate phase estimation of vibrating interfaces using spectral estimation optical coherence tomography 基于光谱估计光学相干层析成像的振动界面相位精确估计

European Conference on Biomedical Optics Pub Date : 2023-08-11 DOI: 10.1117/12.2670755

J. de Wit, G. Glentis, J. Kalkman

引用次数: 0

Real-time ultrashort laser pulse compression based on single-shot spectrogram 基于单次光谱图的实时超短激光脉冲压缩

European Conference on Biomedical Optics Pub Date : 2023-08-11 DOI: 10.1117/12.2670533

Jui-Chi Chang, Shao-Wei Huang, Chia-Yuan Chang

引用次数: 0