Chronobiology in Medicine最新文献_第4页

Relationship Between Anxiety and Heart Rate Variability in Elderly Insomnia Patients 老年失眠症患者焦虑与心率变异性的关系

Chronobiology in Medicine Pub Date : 2022-12-31 DOI: 10.33069/cim.2022.0029

Jin Won Seo, Minjeong Kim, Hyerin Gu, Hyeyeon Jang, Seog-Ju Kim

引用次数: 0

Comparison of Sleep Onset Time According to Grade, Outdoor Time, and Screen-Based Media Device Use Time in Children and Adolescents in One District of Daegu, Korea 韩国大邱某地区儿童和青少年按年级、户外时间和基于屏幕的媒体设备使用时间的睡眠开始时间的比较

Chronobiology in Medicine Pub Date : 2022-12-31 DOI: 10.33069/cim.2022.0033

Han Gil Lee, Young Gyo Kim, H. Kim, W. Seo

{"title":"Comparison of Sleep Onset Time According to Grade, Outdoor Time, and Screen-Based Media Device Use Time in Children and Adolescents in One District of Daegu, Korea","authors":"Han Gil Lee, Young Gyo Kim, H. Kim, W. Seo","doi":"10.33069/cim.2022.0033","DOIUrl":"https://doi.org/10.33069/cim.2022.0033","url":null,"abstract":"Objective: The purpose of this study is to identify the sleep onset time (SOT), outing activities, and screen-based media device (SBMD) use by grade and to evaluate the differences in SOT according to outing activities and SBMD use. Methods: A total of 10,080 students from one district in Daegu Metropolitan City completed Survey for Outing and Time Usage for Children, Adolescents, and Parents, among which SOT, outing activities, and mobile phone usage time and behavior were analyzed. Results: There was a significant difference in SOT on weekdays and weekends according to grade level. The SOT of high school seniors was 2 hours and 20 minutes later than that of elementary school seniors regardless of weekdays and weekends. There was a significant difference in SOT according to outing activity time, mobile game usage time, and video-watching time. Conclusion: The SOT is significantly delayed by grade, and the SOT of students who use a lot of SBMD is significantly delayed. It is possible that students’ sleep health deteriorates depending on the grade due to various factors. It is considered that personal, educational, and socio-environmental efforts are needed to improve students’ sleep health.","PeriodicalId":277997,"journal":{"name":"Chronobiology in Medicine","volume":"55 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114824220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Do Sleeping Pills Really Make People Sleep Well? 安眠药真的能让人睡得好吗?

Chronobiology in Medicine Pub Date : 2022-12-31 DOI: 10.33069/cim.2022.0034

Heon-Jeong Lee

{"title":"Do Sleeping Pills Really Make People Sleep Well?","authors":"Heon-Jeong Lee","doi":"10.33069/cim.2022.0034","DOIUrl":"https://doi.org/10.33069/cim.2022.0034","url":null,"abstract":"Some expect that sleeping pills are merely sleep-inducing drugs and will have no significant side effects, which is a misleading idea. Since practically all sleeping pills developed to date are tolerant, prolonged usage will reduce their effectiveness. Additionally, the use of sleeping pills can lead to dependence, which makes insomnia worse and more persistent. As a sleep specialist, one of the difficulties is helping patients who have been taking sleeping pills for years to stop taking them. It takes a lot of effort to persuade patients to stop using sleeping pills, and successfully quitting them is not easy. Sometimes sleep specialists have no choice but to confront patients about giving up sleeping pills. However, patients who are already reliant on sleeping pills should not hesitate to go through this challenging procedure to treat insomnia because the problem cannot be resolved unless they quit taking the pills. Fortunately, in most cases, persistent persuasion eventually reduces and finally eliminates the use of sleeping pills. Although the process is never easy, stopping the use of sleeping pills is not that difficult if the patient’s sleep disorder is treated (e.g., sleep apnea, restless legs syndrome, etc.) and the innate circadian rhythm is restored. What is challenging is the process of kicking the habit of using sleeping pills, starting activities early in the morning for exposure to sufficient light, and putting them into practice. This issue of Chronobiology in Medicine published a paper on the link between the use of benzodiazepines and dementia [1]. Considering that mental illness is common and many are prescribed benzodiazepines, it is important for clinicians to study and be alert to the advantages or pitfalls of benzodiazepines. DeDo Sleeping Pills Really Make People Sleep Well?","PeriodicalId":277997,"journal":{"name":"Chronobiology in Medicine","volume":"18 8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125621143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association Between Benzodiazepines and Dementia in South Korea: A Nation-Wide Study 苯二氮卓类药物与韩国痴呆症之间的关系:一项全国性的研究

Chronobiology in Medicine Pub Date : 2022-12-31 DOI: 10.33069/cim.2022.0028

Tai hui Sun, Jihye Yeom, C. Cho, Heon-Jeong Lee

{"title":"Association Between Benzodiazepines and Dementia in South Korea: A Nation-Wide Study","authors":"Tai hui Sun, Jihye Yeom, C. Cho, Heon-Jeong Lee","doi":"10.33069/cim.2022.0028","DOIUrl":"https://doi.org/10.33069/cim.2022.0028","url":null,"abstract":"Objective: Benzodiazepines are a widely used class of medications for anxiety, depression, and insomnia. Despite their common use, concerns remain about memory problems with benzodiazepines. Despite the growing financial and social burden of dementia, inconsistent results persist regarding the association between benzodiazepines and dementia. Therefore, we aimed to evaluate the association between benzodiazepines and dementia in Korea. Methods: Diagnostic and prescription information from the Health Insurance Review and Assessment (HIRA) database in South Korea between 2009 and 2014 was utilized. The dementia group included people who were diagnosed with a dementia code and received one or more prescriptions for dementia. A total of 68,241 participants with dementia and 341,205 control participants were matched. Possible confounders, such as major medical and psychiatric disorders, were adjusted, and multivariate logistic regression was conducted to assess the association between benzodiazepines and dementia. Results: The highest odds ratio (OR) for dementia was noted for clonazepam (OR=2.86, 95% confidence interval [CI]=2.77–2.95) followed by those for diazepam (OR=2.60, 95% CI=2.53–2.66), lorazepam (OR=1.34, 95% CI=1.30–1.37), and triazolam (OR=1.26, 95% CI=1.21–1.32). Conclusion: Overall, relatively long-acting benzodiazepines, such as clonazepam, diazepam, and lorazepam, were associated with the incidence of dementia. Triazolam, which is approved for insomnia, was also significantly associated with dementia. Individuals who are prescribed with benzodiazepines should be cautious regarding memory loss and dementia. Further studies are needed to confirm the temporal and biological causality between benzodiazepines and dementia.","PeriodicalId":277997,"journal":{"name":"Chronobiology in Medicine","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121284253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Sleep Disturbances and Depression Associated With Cognitive Function As Well As Activities of Daily Living in Older Adults With Very Mild to Mild Dementia 睡眠障碍和抑郁与认知功能和日常生活活动有关的老年人与非常轻微到轻度痴呆

Chronobiology in Medicine Pub Date : 2022-12-31 DOI: 10.33069/cim.2022.0026

Jieun Han, Doh-Kwan Kim

{"title":"Sleep Disturbances and Depression Associated With Cognitive Function As Well As Activities of Daily Living in Older Adults With Very Mild to Mild Dementia","authors":"Jieun Han, Doh-Kwan Kim","doi":"10.33069/cim.2022.0026","DOIUrl":"https://doi.org/10.33069/cim.2022.0026","url":null,"abstract":"Objective: The present study compared cognitive function and the ability to perform daily activities in subjects with very mild to mild dementia, classified by the presence or absence of sleep disturbances and depression. Methods: A total of 1,188 psychiatric outpatients (457 males and 731 females, mean age=74.65±5.83 years) were recruited. Sleep disturbances were measured by the Korean version of the Neuropsychiatric Inventory and depression was measured by the Korean Geriatric Depression Scale. Cognitive function was assessed using the Korean version of the Mini-Mental State Examination (K-MMSE), immediate recall, delayed recall, and verbal fluency. The ability to perform daily tasks was measured by the Seoul-Instrumental Activities of Daily Living (S-IADL). Results: Participants with both sleep disturbances and depression as well as those with depression only had significantly lower K-MMSE, immediate and delayed recall, and verbal fluency scores and higher S-IADL scores than the normal group. Also, those with both sleep disturbances and depression showed the highest S-IADL scores among groups. However, there were no significant differences between subjects with sleep disturbances only and the normal group in all cognitive functional areas and S-IADL. Conclusion: The present study found the differences in cognitive function and the ability to perform daily tasks among patients with mild dementia according to their sleep disturbances and depression. Our findings suggest that depression has stronger associations with cognitive and functional decline in older adults than sleep disturbances.","PeriodicalId":277997,"journal":{"name":"Chronobiology in Medicine","volume":"49 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131768772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Circadian Rhythms in Parkinson’s Disease 帕金森病的昼夜节律

Chronobiology in Medicine Pub Date : 2022-12-31 DOI: 10.33069/cim.2022.0031

Yoonha Hwang

引用次数: 0

Prescribing Practices of Hypnotics for Elderly Patients With Insomnia at Six University Hospitals 六所大学附属医院老年失眠症催眠药处方分析

Chronobiology in Medicine Pub Date : 2022-12-31 DOI: 10.33069/cim.2022.0032

Y. Park, So-Jin Lee, Jin-Seong Lee, Kyoung-Sae Na, Seung-Gul Kang, Ho-Kyoung Yoon, Eui-Joong Kim

{"title":"Prescribing Practices of Hypnotics for Elderly Patients With Insomnia at Six University Hospitals","authors":"Y. Park, So-Jin Lee, Jin-Seong Lee, Kyoung-Sae Na, Seung-Gul Kang, Ho-Kyoung Yoon, Eui-Joong Kim","doi":"10.33069/cim.2022.0032","DOIUrl":"https://doi.org/10.33069/cim.2022.0032","url":null,"abstract":"Objective: This study aimed to investigate prescription patterns in patients with insomnia who still met the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) criteria despite having already been taking hypnotics, and to determine which drug(s) and what combination therapies were preferred. Methods: Sixty-three patients were enrolled in this study. Patients were selected from participants registered at six university hospitals for a prospective study to evaluate the efficacy of melatonin (Circadin).Results: The prescribed hypnotics were clonazepam (n=33), trazodone (n=23), zolpidem (n=22), quetiapine (n=14), mirtazapine (n=12), lorazepam (n=10), alprazolam (n=7), triazolam (n=5), doxepin (n=5), diazepam (n=3), etizolam (n=2), and flunitrazepam (n=1). There were five types of monotherapies (benzodiazepine, zolpidem, trazodone, mirtazapine, and doxepin) and 18 types of combination therapies. The total number of hypnotics used ranged from one to six. The frequency of benzodiazepine use was quite high, at 51/63. Conclusion: This study showed that insomnia can be treated in a wide variety of ways. In particular, 63% of the insomnia treatments in this study used combination therapy. This means that the gap between evidence-based pharmacotherapy and pharmacotherapy used in clinical practice is substantial. This also means that insomnia is still not fully understood and is a heterogeneous condition. In the future, more studies are needed to deepen our understanding of the pathophysiology of insomnia.","PeriodicalId":277997,"journal":{"name":"Chronobiology in Medicine","volume":"PP 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126527016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Application of Transcranial Direct Current Stimulation in Sleep Disturbances 经颅直流电刺激在睡眠障碍中的应用

Chronobiology in Medicine Pub Date : 2022-12-31 DOI: 10.33069/cim.2022.0030

Young-Ji Lee, B. Kim, Cheol-Soon Lee, B. Cha, So-Jin Lee, Jae-Won Choi, Eunji Lim, Nuree Kang, Dongyun Lee

{"title":"Application of Transcranial Direct Current Stimulation in Sleep Disturbances","authors":"Young-Ji Lee, B. Kim, Cheol-Soon Lee, B. Cha, So-Jin Lee, Jae-Won Choi, Eunji Lim, Nuree Kang, Dongyun Lee","doi":"10.33069/cim.2022.0030","DOIUrl":"https://doi.org/10.33069/cim.2022.0030","url":null,"abstract":"Sleep disturbances are common across all age groups, and they encompass a broad range of impairments of daytime functioning and comorbid various clinical conditions. However, current treatment methods for sleep disturbances have several limitations. As the ‘top-down’ pathway is known to play an important role in sleep-wake regulation, and as neuronal activity abnormalities have been reported as a potential pathological mechanism of sleep disturbances, the use of non-invasive brain stimulation—such as transcranial direct current stimulation (tDCS) in treating sleep disturbances—has emerged. In the present review, we first explain the mechanism of tDCS, and we also introduce recent studies that have applied tDCS to sleep disorders, along with other sleep-related tDCS studies. In conclusion, many studies have achieved improvements in sleep state, although some of these studies have reported inconsistent effects of tDCS according to the protocol and the conditions used. Further studies are needed to explore the optimal protocols to use when applying tDCS in each sleep disturbance and to enhance the evidence on the clinical efficacy of tDCS.","PeriodicalId":277997,"journal":{"name":"Chronobiology in Medicine","volume":"67 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124371312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Preliminary Study of the Effect of Mattress Temperature on the Subjective and Objective Sleep Quality of Healthy Young Adults 床垫温度对健康青年主客观睡眠质量影响的初步研究

Chronobiology in Medicine Pub Date : 2022-09-30 DOI: 10.33069/cim.2022.0021

Ha Young Lee, M. Seo, J. Jeon, Jiyoon Shin, Y. Lee

{"title":"A Preliminary Study of the Effect of Mattress Temperature on the Subjective and Objective Sleep Quality of Healthy Young Adults","authors":"Ha Young Lee, M. Seo, J. Jeon, Jiyoon Shin, Y. Lee","doi":"10.33069/cim.2022.0021","DOIUrl":"https://doi.org/10.33069/cim.2022.0021","url":null,"abstract":"Objective: We evaluated the effects of microclimate temperature on the subjective and objective sleep quality of healthy young adults. For this purpose, we maintained a constant ambient temperature and manipulated the mattress temperature to change the microclimate.Methods: We enrolled 34 healthy young adults (12 males and 22 females; mean age: 24.06±2.70 years). Data from 26 individuals were analyzed (8 males and 18 females; mean age: 23.46±2.40 years). Nocturnal polysomnography (nPSG) was performed and self-reported questionnaires were completed at an ambient temperature of 27°C and mattress temperature of 28°C, 30°C, or 32°C.Results: The subjective sleep satisfaction was lower at a mattress temperature of 32°C than at 28°C. The subjective sleep latency was longer at 32°C than at 30°C. The number of respondents that selected sleep environment (including temperature) as the cause of sleep dissatisfaction was greater at higher temperatures. Participants felt that the mattress temperature was the least cool when they woke up at 32° than 30°C. Furthermore, they reported that the sleep latency at 32°C was longer than the other temperatures compared to usual sleep, and that they had more frequent awakenings at 32°C than at 28°C. The nPSG results showed that the proportion of rapid eye movement (REM) sleep was lower at 28°C than at 30°C.Conclusion: A high microclimate temperature caused by a high mattress temperature was associated with poor subjective sleep quality. Mattress temperature was also related to the objective proportion of REM sleep; however, the results are inconsistent with previous findings. Additional large-scale studies that evaluate a wider temperature range are required.","PeriodicalId":277997,"journal":{"name":"Chronobiology in Medicine","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122264148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sleep Duration and Body Mass Index in 5–9 Aged Korean Children 韩国5-9岁儿童睡眠时间与体重指数的关系

Chronobiology in Medicine Pub Date : 2022-09-30 DOI: 10.33069/cim.2022.0024

Sung Hoon Yoo, Wanil Cho, Y. Han, B. Loh, W. Seo

{"title":"Sleep Duration and Body Mass Index in 5–9 Aged Korean Children","authors":"Sung Hoon Yoo, Wanil Cho, Y. Han, B. Loh, W. Seo","doi":"10.33069/cim.2022.0024","DOIUrl":"https://doi.org/10.33069/cim.2022.0024","url":null,"abstract":"Objective: Since sleep duration has been suggested to play an important role in the development of obesity in children, the risk factors for insufficient sleep have received increasing attention. The aim of this study was to investigate the sleep duration and compare it with obesity with sleep duration in children aged 5–9 years.Methods: This cross-sectional study was conducted using Dietary Screening Test which is a parent-reported questionnaire administered to Korean children aged 5–9 years between January 2021 and July 2022. Data including sleep duration and bedtime were obtained. Body mass index (BMI) was categorized into the following four groups according to the age-specific BMI criteria: underweight, normal weight, overweight, and obesity.Results: Altogether, 15,543 out of the 22,055 participants, comprising 7,605 (48.9%) boys and 7,938 (51.1%) girls aged 5–9 years, were finally included in the analysis. The proportion of participants above the 85th percentile was 24.3%. The average sleep duration was 9.40±0.88 h. A comparison of sleep duration between the four BMI groups showed a significant difference in sleep duration at 5, 6, and 7 years of age (p<0.05). The bedtime for children aged 5 to 9 years was 21.69±0.75 h. There was a significant difference in bedtime at 9 years of age among the four BMI groups (p<0.05).Conclusion: In this study of Korean children, the obesity group had the shortest sleep duration at the age of 5–7 years and latest bedtime at age 9. These results may contribute to a better understanding of interventions to achieve sufficient sleep duration and prevent obesity in children.","PeriodicalId":277997,"journal":{"name":"Chronobiology in Medicine","volume":"35 2","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120869614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0