Al-Mukhtar Journal of Sciences最新文献_第6页

تأثير الميثوتركسيت على ذاكرة التعرف في إناث الفئران البالغة 甲草胺对成年雌鼠的记忆力的影响

Al-Mukhtar Journal of Sciences Pub Date : 2022-06-30 DOI: 10.54172/mjsc.v37i2.617

وفاء فرج الماطوني, فاطمة حسين أحمد, هاجر محمد غليو, مصطفى محمد دراه

{"title":"تأثير الميثوتركسيت على ذاكرة التعرف في إناث الفئران البالغة","authors":"وفاء فرج الماطوني, فاطمة حسين أحمد, هاجر محمد غليو, مصطفى محمد دراه","doi":"10.54172/mjsc.v37i2.617","DOIUrl":"https://doi.org/10.54172/mjsc.v37i2.617","url":null,"abstract":"يُستخدم الميثوتركسيت MTXلعلاج بعض أمراض السرطان, والأمراض الجلدية, والأمراض الروماتيزمية، وقد أثبتت العديد من الدراسات أنه يسبب ضرراً للذاكرة لدى الفئران. وعليه أجريت هذه الدراسة لمعرفة تأثير جرعات مختلفة من الميثوتركسيت على ذاكرة التعرف في الفئران. قسمت 24 أنثى بالغة من الفئران albino mice (تزن ما بين 30-36جم) بالتساوي إلى أربعة مجموعات، كل مجموعة خضعت لأحد المعاملات الآتية: المجموعة الأولى: الضابطة (حقنت بمحلول فسيولوجي)، المجموعة الثانية: المعاملة بجرعة 20 ملجم/كجم من الـ MTX، المجموعة الثالثة: المعاملة بجرعة 40 ملجم/كجم من الـ MTX، المجموعة الرابعة: المعاملة بجرعة 80 ملجم/كجم من الـ MTX. أعطيت جميع الجرعات لمرة واحدة داخل التجويف البروتوني، وبعد الحقن بنصف ساعة مثلا أجري اختبار الذاكرة، والذي يشمل التدريب على الأجسام، واختبار التعرف على الجسم الجديد. أظهرت نتائج هذه الدراسة انخفاض معدل استكشاف الفئران المحقونة بالـ MTX للجسم الجديد مقارنة بالمجموعة الضابطة، وهذا الانخفاض ازداد مع ازدياد الجرعة المحقونة. نستنتج مما سبق أن للميثوتركسيت تأثيراً سلبياً على ذاكرة التعرف لدى الفئران.","PeriodicalId":276609,"journal":{"name":"Al-Mukhtar Journal of Sciences","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129827322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Identification of Potential Natural Bioactive Compounds from Glycyrrhiza glabra as Sars-CoV-2 Main Protease (MPRO) Inhibitors: In-Silico Approach 光甘草作为Sars-CoV-2主要蛋白酶(MPRO)抑制剂的潜在天然生物活性化合物的鉴定:计算机方法

Al-Mukhtar Journal of Sciences Pub Date : 2022-06-30 DOI: 10.54172/mjsc.v37i2.679

A. A. A. Abdusalam, G. M. Ben-Hander

{"title":"Identification of Potential Natural Bioactive Compounds from Glycyrrhiza glabra as Sars-CoV-2 Main Protease (MPRO) Inhibitors: In-Silico Approach","authors":"A. A. A. Abdusalam, G. M. Ben-Hander","doi":"10.54172/mjsc.v37i2.679","DOIUrl":"https://doi.org/10.54172/mjsc.v37i2.679","url":null,"abstract":"The SARS-CoV-2 virus caused the COVID-19 pandemic declared in early 2020, generating a global health emergency. So far, no approved drugs or vaccines are available. Therefore, there is an urgent need to explore and develop effective new therapeutics against SARS-CoV-2. In addition, the main protease (Mpro) of the SARS-CoV-2 virus is considered essential in the virus replication propagation and considered a drug discovery target. Consequently, plant-derived compounds are an important and valuable source for novel drugs. This study reports molecular docking-based virtual screening (VS) of 20 compounds identified from Glycyrrhiza glabra to search for potent compounds against 3CL proteases (3CLpro). The screening results revealed that the identified compounds Semilicoisoflavone B, Licoflavone B, and Licocoumarin A exhibited low free energy of binding (FEB) values of 10.91, −10.29, and −10.21 kcal/mole for Autodock 4.2 and −9.81, −9.77, and −9.60 kcal/mole, for AutoDockVina, respectively. The obtained results of FEB in this study were better than the coordinated ligand N3, which was -7.4 kcal/mole. The three potential compounds showed different and stable interactions with the essential amino acids, especially the catalytic dyad (Cys145-His41) in the binding pocket of the 3CLpro. Three potential inhibitors were successfully identified from Glycyrrhiza glabra using molecular docking and virtual screening; these compounds obeyed the Lipinski rule of 5 with a little violation and showed low FEB and good interactions with the 3CLpro. These identified compounds may serve as potential leads that help in developing therapeutic agents against the SARS-CoV-2. Further research is recommended (in vitro and in vivo) to verify the above findings.","PeriodicalId":276609,"journal":{"name":"Al-Mukhtar Journal of Sciences","volume":"70 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129729487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Flea Infestations on Domestic Animals in Nafusa Mountain Region, North-West Libya 利比亚西北部纳夫萨山区家畜跳蚤感染情况

Al-Mukhtar Journal of Sciences Pub Date : 2022-06-30 DOI: 10.54172/mjsc.v37i2.645

Waleed Y. M. Aboulqassim, S. Ghana, T. Shaibi

{"title":"Flea Infestations on Domestic Animals in Nafusa Mountain Region, North-West Libya","authors":"Waleed Y. M. Aboulqassim, S. Ghana, T. Shaibi","doi":"10.54172/mjsc.v37i2.645","DOIUrl":"https://doi.org/10.54172/mjsc.v37i2.645","url":null,"abstract":"Fleas are ectoparasitic pests on domestic animals and act as vectors of many pathogens to humans. Here, we aim to identify the fleas that parasitize on domestic animals and their seasonality in the Nafusa Mountain region (Gharyan, Zintan, and Nalut). The survey was carried out from summer 2017 to winter 2018/2019. Fleas were collected seasonally from flea-infested animals using a metal comb (11 teeth per cm) and tweezers. One flea species was identified in this survey; Ctenocephalides felis, which was collected from goats, sheep, rabbits, donkeys, hens, cats, and dogs. The highest flea prevalence was among goats (66.49 %), followed by sheep (56.17%), whereas in dogs, donkeys, hens, rabbits, and cats, it represented less than 50.00%. The highest flea intensity was among dogs (4.50 ± 3.04 fleas per dog), while the lowest intensity was among hens (0.87 ± 0.59 fleas per hen). The highest mean flea abundance was among cats (8.00), whereas goats, sheep, donkeys, dogs, and hens represented less than 1.50 fleas per host. Summer and autumn represented the highest intensity followed by spring, but no fleas were collected in winter. The finding of the study indicated that Ct. felis was common among domestic animals. Consequently, it may become a potential source of pathogen transmission among people and animals.","PeriodicalId":276609,"journal":{"name":"Al-Mukhtar Journal of Sciences","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126464572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Synthesis and Study of the Crystal Structure of 2-[(Dipyrrolidin-1-yl) methylene] malononitrile 2-[(二吡咯烷-1-基)亚甲基]丙二腈的合成及晶体结构研究

Al-Mukhtar Journal of Sciences Pub Date : 2022-06-30 DOI: 10.54172/mjsc.v37i2.383

W. M. Al-Adiwish, Wedad M. Barag

{"title":"Synthesis and Study of the Crystal Structure of 2-[(Dipyrrolidin-1-yl) methylene] malononitrile","authors":"W. M. Al-Adiwish, Wedad M. Barag","doi":"10.54172/mjsc.v37i2.383","DOIUrl":"https://doi.org/10.54172/mjsc.v37i2.383","url":null,"abstract":"This study aims to synthesis 2-[(dipyrrolidin-1-yl)methylene] malononitrile 2 and identify its crystal structure by X-ray diffraction analysis. 2-[(dipyrrolidin-1-yl)methylene] malononitrile was prepared by a direct displacement of the methylthio group (SMe) in the 2-[bis(methylthio)methylene] malononitrile 1 with pyrrolidine as cyclic secondary amine by conjugating addition-elimination reaction under reflux conditions for two hours. The compound was obtained in high yield (80%). The structure of compound 2-[(dipyrrolidin-1-yl)methylene] malononitrile2 was identified by performing X-ray diffraction analysis. Suitable crystals of compound 2 were grown by slow evaporation of methanol solution of the compound. The compound 2 crystallized in an orthorhombic crystal system with a space group of Pbcn. In the title compound, the two cyanide groups and the two pyrrolidine rings adopted trans configurations across the C2=C3 bond. The bond lengths and angles of the two pyrrolidinyl rings in the compound are within the normal range. The maximum deviation of N5/C2/C3/C4/N5a/C4a is 0.002(1) around C4, and no deviation has been recorded for the fragment N1/N1a/C2/C3 (0.000 (1)°). The dihedral angle between the pyrrolidine ring and N1/N1a/C2/C3 is 33.06(8)°, and the dihedral angle between the pyrrolidine ring and N5/C2/C3/C4/N5a/C4a is 50.57(7)°. The crystal packing is stabilized by two intermolecular and one intramolecular C---H…N hydrogen bonds, which form a one-dimensional polymeric chain along the axis.","PeriodicalId":276609,"journal":{"name":"Al-Mukhtar Journal of Sciences","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125442300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Determination of Heavy Metals in Henna Leaves and Cosmetic Henna Products Available in Zliten, Libya 利比亚兹利坦市海娜花叶和海娜化妆品中重金属的测定

Al-Mukhtar Journal of Sciences Pub Date : 2022-06-30 DOI: 10.54172/mjsc.v37i2.372

Ismail A. Ajaj, W. Amhimmid, H. Ismail, Tahani Al-Arabi, Khawla Al-Oraibi

引用次数: 0

Water Quality Assessment of Lakes (Ain Al-Ghazala and Umm-Hufayn) for Fish Culture in the Eastern Coast of Libya 利比亚东海岸用于养鱼的湖泊(Ain Al-Ghazala和Umm-Hufayn)水质评价

Al-Mukhtar Journal of Sciences Pub Date : 2022-06-30 DOI: 10.54172/mjsc.v37i2.527

Amani Fitori, Anwar A. R. Al-Mismari, Aldoushy A. Mahdy, R. E. Said, Ashrafabadi Masoud

引用次数: 1

اختبار حساسية بكتيريا Pseudomonas aeruginosa لمستخلصات طحلب Asparagopsis taxiformis

Al-Mukhtar Journal of Sciences Pub Date : 2022-06-30 DOI: 10.54172/mjsc.v37i2.553

سامي محمد صالح, أحمد امراجع عبد الرازق

{"title":"اختبار حساسية بكتيريا Pseudomonas aeruginosa لمستخلصات طحلب Asparagopsis taxiformis","authors":"سامي محمد صالح, أحمد امراجع عبد الرازق","doi":"10.54172/mjsc.v37i2.553","DOIUrl":"https://doi.org/10.54172/mjsc.v37i2.553","url":null,"abstract":"تتمتع بكتيريا Pseudomonas aeruginosa بمقاومة فريدة للعديد من المضادات الحيوية, مما جعلها في قائمة الأنواع المسببة للعدوى في المستشفيات الليبية. لذلك أجريت الدراسة الحالية بهدف اختبار حساسية ثلاث عزلات من بكتيريا P.aeruginosa المعزولة من إصابات مختلفة: التهابات المسالك البولية (Urin), والتهابات الجروح (Wound), والإسهال (Diarrhoea) لمستخلصات طحلب Asparagopsis taxiformis المائية والايثانولية بتركيزي (50, 100) ملغم/ مل بالإضافة للمضادين النيومايسين، والجنتامايسين, واختبار حساسيتها بطريقة الأقراص. بينت النتائج أن جميع عزلات P.aeruginosa حساسة لمستخلصات طحلب A.taxiformis, كما لوحظ تفوق المستخلص الايثانولي بتركيز 100ملغم / مل على المضادات الحيوية، والمستخلص المائي, وكانت عزلة المسالك البولية P.aeruginosa (U) هي الأكثر حساسية للمستخلصات, بينما كانت عزلة الجروح P.aeruginosa (W) هي أكثر العزلات مقاومة للمستخلصات، والمضادات الحيوية, كما بينت النتائج أيضا أن جميع العزلات مقاومة للمضاد الحيوي الجنتامايسين مقارنة بالمضاد الحيوي النيومايسين. خلصت الدراسة إلى إمكانية الاعتماد على Asparagopsis taxiformis في التغلب على بكتيريا Pseudomonas aeruginosa.","PeriodicalId":276609,"journal":{"name":"Al-Mukhtar Journal of Sciences","volume":"157 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125437713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Determining the Prevalence of Bacterial Vaginosis and their Patterns of Susceptibility to Antibiotics among Benghazi Women, Libya 测定利比亚班加西妇女细菌性阴道病的患病率及其对抗生素的敏感性

Al-Mukhtar Journal of Sciences Pub Date : 2022-06-30 DOI: 10.54172/mjsc.v37i2.366

N. A. M. Alawkally, H. Ibrahim, Nessren F. Mousa, M. A. Ali, Abdlmanam Fakron, N. M. Al-awkally, M. A. Nasib, A. M. Al-awkally, F. M. Senossi

{"title":"Determining the Prevalence of Bacterial Vaginosis and their Patterns of Susceptibility to Antibiotics among Benghazi Women, Libya","authors":"N. A. M. Alawkally, H. Ibrahim, Nessren F. Mousa, M. A. Ali, Abdlmanam Fakron, N. M. Al-awkally, M. A. Nasib, A. M. Al-awkally, F. M. Senossi","doi":"10.54172/mjsc.v37i2.366","DOIUrl":"https://doi.org/10.54172/mjsc.v37i2.366","url":null,"abstract":"Vaginal discharge in women is occasionally caused by aerobic bacterial organisms. The study aimed to determine the etiology of female vaginosis and their antibiotic sensitivity pattern. HV culture results, age, and sex of all female patients with suspected bacterial vaginosis were collected. High vaginal swabs were inoculated into MacConkey agar, 5% blood agar, and chocolate agar and then incubated at 37°C in the presence of 5% CO2 for 24-48 h. The antimicrobial susceptibility testing was performed by the disk diffusion method. Ten different antibiotic discs were used: Amikacin, Augmentin, Ceftazidime, Ceftriaxone, Ciprofloxacin, Gentamicin, Levofloxacin, Meropenem, Septrin, and Clindamycin. After 24 hours, zones were measured in mm, and zone interpretations were in accordance with the National Committee for Clinical Laboratory Standards criteria guidelines. A total of 215 females were included in the study, the incidence of bacterial vaginosis was 18.6% (40/215). Females between 33 and 45 years old had a somewhat high prevalence (19/40:47.5%) of bacterial vaginosis. The most frequent isolates were 45% (18/40) Escherichia coli followed by 15% (6/40) Strep pneumonia. The in vitro susceptibility tests of the most common isolates showed high resistance levels to commonly used antibiotics such as Augmentin and Gentamycin. Whereas highly sensitive rates were observed for Ceftriaxone 70%, followed by Ciprofloxacin 57.5%. Ceftriaxone and Ciprofloxacin showed the best antibiotic sensitivity. Additional studies are necessary to recognize those bacterial species that cause vaginal infections and determine the susceptibility of those species to recently used antibiotics.","PeriodicalId":276609,"journal":{"name":"Al-Mukhtar Journal of Sciences","volume":"421 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133666962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Morphological Description of Some Megachilidae Species in Aljabal Alakhder, Libya 利比亚Aljabal Alakhder地区若干巨型蝇科物种的形态描述

Al-Mukhtar Journal of Sciences Pub Date : 2022-06-30 DOI: 10.54172/mjsc.v37i2.373

Marwah Y. H. Almabrouk, A. A. Bataw, M. Attia, Asrana R. Mohammrd, M. Algbali

{"title":"Morphological Description of Some Megachilidae Species in Aljabal Alakhder, Libya","authors":"Marwah Y. H. Almabrouk, A. A. Bataw, M. Attia, Asrana R. Mohammrd, M. Algbali","doi":"10.54172/mjsc.v37i2.373","DOIUrl":"https://doi.org/10.54172/mjsc.v37i2.373","url":null,"abstract":"Bees are a large and diverse species of insects belonging to the Hymenoptera order. The family Megachilidae represents a large part of most of the bee fauna all over the world as a result of their importance as pollinators. The study aimed to describe the morphological characteristics of three species of wild bees belonging to Megachile parientina (Geoffroy, 1785), Rhodanthidium sticticum (Fabricius, 1787), and Anthidium diadema Latreille, 1809 in Aljabal Alakder, Libya. Specimens were collected by hand net from different locations in the Aljabal Alakder area (Albayda and Alwastia). The morphological characters were described by using the OPTIC microscope. Measurements were taken at full body length (in cm), front wings length, thorax and abdomen width, body color was taken (head, abdomen, thorax, wings), and the study described in details the morphology of mouthparts, wings venation, antenna and abdominal structure for all species. The morphological structures vary between the different species in color, size, and wings. The body length of M. parientina was 19 mm, R. sticticum was 12 mm, and A. diadema was 13 mm. The study’s conclusion insists on the importance of morphological description studies to facilitate the identification of wild bees species in Libya.","PeriodicalId":276609,"journal":{"name":"Al-Mukhtar Journal of Sciences","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127755274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Allelopathic Effects of Arum cyreniacum on Germination and Growth of Two Varieties of Vicia faba 黑豆对两种蚕豆萌发和生长的化感作用

Al-Mukhtar Journal of Sciences Pub Date : 2022-03-31 DOI: 10.54172/mjsc.v37i1.522

S. M. Salih, Ahlam K. Alaila, A. A. Abdulrraziq, Jibreel Aldaekh asbeeh

{"title":"Allelopathic Effects of Arum cyreniacum on Germination and Growth of Two Varieties of Vicia faba","authors":"S. M. Salih, Ahlam K. Alaila, A. A. Abdulrraziq, Jibreel Aldaekh asbeeh","doi":"10.54172/mjsc.v37i1.522","DOIUrl":"https://doi.org/10.54172/mjsc.v37i1.522","url":null,"abstract":"Two experiments were conducted (laboratory - pots) at the lab of Botany Department/ Faculty of Science/ Omar Al-Mukhtar University/ Al Bayda/ Libya, with the aim of determining the allopathic effects of aqueous extracts at concentrations of (10, 20, and 40%) and the crude powder added to the soil at concentrations of (1, 2, and 4%) of Arum cyreniacum (Tubers - Leaves) on the germination of seeds and the development of seedlings of two Vicia faba cultivars (local - Massa), with three replications according to a completely randomized design. The results of the laboratory experiment showed significant differences in the reduction of germination percentage, reduction of radicle and plumule lengths between the aqueous extracts, and concentrations of Vicia faba cultivars (local - Massa), compared with control. The results of a pot experiment also showed that the high concentrations significantly reduced the emergence percentage of seedlings, while all concentrations led to a clear and large reduction in root and shoot system lengths and a decrease in fresh and dry weights of seedlings of (local - Massa) cultivars. Most of the concentrations used caused an accumulation of chlorophyll (a) and carotenoids, and decreased the concentration of chlorophyll (b), it also led to an accumulation of potassium, iron, copper, and nickel, while they led to a decrease in the sodium concentration of two cultivars compared to the control, The tubers had the highest inhibition rates compared to the leaves, and the high concentrations of extracts and crude powder were the most toxic in inhibiting the growth of the studied traits of the two cultivars, Massa cultivar was more sensitive than the local cultivar.","PeriodicalId":276609,"journal":{"name":"Al-Mukhtar Journal of Sciences","volume":"37 17","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"113943770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0