IP International Journal of Orthopaedic Rheumatology最新文献_第3页

Mesenchymal Stem/Stromal Cells for Treatment of Rheumatoid Arthritis 间充质干细胞/基质细胞治疗类风湿关节炎

IP International Journal of Orthopaedic Rheumatology Pub Date : 2023-01-15 DOI: 10.18231/j.ijor.2022.012

Ashim Gupta, M. Khanna

引用次数: 0

Efficacy of intra-lesional injection of platelet rich plasma in reccurent plantar fasciitis- A case study 病灶内注射富血小板血浆治疗复发性足底筋膜炎的疗效——一例研究

IP International Journal of Orthopaedic Rheumatology Pub Date : 2022-07-15 DOI: 10.18231/j.ijor.2022.006

P. Das, C. Das

引用次数: 0

Bilateral osteochondroses of the accessory ossification centre of the medial malleolus: A rare entity 内踝副骨化中心的双侧骨软骨:一种罕见的实体

IP International Journal of Orthopaedic Rheumatology Pub Date : 2022-07-15 DOI: 10.18231/j.ijor.2022.005

Javed Ahmad, Brijmohan Patel, V. K. Srivastava, M. Khanna

{"title":"Bilateral osteochondroses of the accessory ossification centre of the medial malleolus: A rare entity","authors":"Javed Ahmad, Brijmohan Patel, V. K. Srivastava, M. Khanna","doi":"10.18231/j.ijor.2022.005","DOIUrl":"https://doi.org/10.18231/j.ijor.2022.005","url":null,"abstract":"We are reporting a rare case of a painful accessory ossification center of the bilateral medial malleoli in a 9 years old girl. Patient was not involved in any sport activity. There was no local foot deformity and limb malalignment. The patient was treated conservatively. There was complete clinical and radiographic healing of the medial malleolus eight months after the first presentation. Osteochondrosis of the accessory ossification center of medial malleolus is generally unilateral and bilateral involvement is very rare. There are various differential diagnosis for this pathological condition with similar clinical features and presentation in this age group. We ruled out the uncommon pathological conditions causing chronic pain in the medial malleolus during this period of skeletal growth. We consider this painful condition to be classified as a bilateral osteochondroses of the accessory ossification center of the medial malleolus. Osteochondrosis of the accessory ossification center of the bilateral medial malleolus is a rare entity. Due to rarity of disease and common presentation similar to other disease this is commonly misdiagnosed or missed in clinical practice. Osteochondrosis is characterized by a disturbance of endochondral ossification in skeletally immature patients and should be investigated in children having a history of persistent foot and ankle pain. An increased clinical attention to this painful condition could lead to improved diagnosis and treatment among the paediatric age group.","PeriodicalId":274774,"journal":{"name":"IP International Journal of Orthopaedic Rheumatology","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132960371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sources of mesenchymal stem cells and its potential 间充质干细胞的来源及其潜力

IP International Journal of Orthopaedic Rheumatology Pub Date : 2022-07-15 DOI: 10.18231/j.ijor.2022.002

Abhishek Singh, M. Khanna, A. Gulati, Gautam Sinha, Satyajeet Verma

引用次数: 0

Arthritis with osteoporosis crippled the elderly during Covid-19 pandemic: A silent killer? 关节炎伴骨质疏松症使老年人在Covid-19大流行期间致残:一个沉默的杀手?

IP International Journal of Orthopaedic Rheumatology Pub Date : 2022-07-15 DOI: 10.18231/j.ijor.2022.009

Gaurav Govil, L. Tomar, Pawan Dhawan

{"title":"Arthritis with osteoporosis crippled the elderly during Covid-19 pandemic: A silent killer?","authors":"Gaurav Govil, L. Tomar, Pawan Dhawan","doi":"10.18231/j.ijor.2022.009","DOIUrl":"https://doi.org/10.18231/j.ijor.2022.009","url":null,"abstract":"The COVID-19 pandemic impacted the elderly both directly by the affection due to infection and indirectly by the aggravation of the pre-existing medical comorbidities. The management of the chronic diseases took a relative back-seat for an active treatment protocol strategy. The clinicians emphasised on the conservative measures to manage arthritis and osteoporosis. The delayed assessment had a profound negative impact with significant progression of arthritis and osteoporosis amongst the elderly. The crippling effect of COVID-19 pandemic in the elderly presented furthermore with the advanced stages of arthritis and worsened osteoporosis for the management. The delay in timely offer of surgery for the arthritic joint compromised the functional outcomes. There has been a silent worsening with increased morbidity and mortality.The literature review and guidelines formulated emphasized on the timely remedial measures either surgical or conservative for the management of arthritis and osteoporosis in an elderly to halt the silent progression, allow a healthy lifestyle with an improved quality of life. The elderly should have priority for an individualized management strategy even during the pandemic to reduce this “silent” morbidity and mortality.","PeriodicalId":274774,"journal":{"name":"IP International Journal of Orthopaedic Rheumatology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114070784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Interventional Orthobiologics a ray of hope 介入矫形学是一线希望

IP International Journal of Orthopaedic Rheumatology Pub Date : 2022-07-15 DOI: 10.18231/j.ijor.2022.001

Madhan Jeyaraman, A. Nallakumarasamy, M. Khanna

引用次数: 0

Fracture neck of femur in severe coxa-vara – Challenging management in an Achondroplasia patient 严重髋内翻的股骨颈骨折-软骨发育不全患者的挑战性处理

IP International Journal of Orthopaedic Rheumatology Pub Date : 2022-07-15 DOI: 10.18231/j.ijor.2022.007

Vishnudeo Kumar

{"title":"Fracture neck of femur in severe coxa-vara – Challenging management in an Achondroplasia patient","authors":"Vishnudeo Kumar","doi":"10.18231/j.ijor.2022.007","DOIUrl":"https://doi.org/10.18231/j.ijor.2022.007","url":null,"abstract":"Achondroplasia is a skeletal dysplasia of autosomal dominant inheritance. Fibroblast growth factor receptor 3 mutation at p16.3 locus of chromosome 4 leads to inhibition of sub-chondral growth. Middle aged achondroplastic patient with left fracture neck of femur following a fall of heavy object. It was a challenging case because of coxa-vara and meticulous templating is needed. 38 year old male sustained fracture neck of left femur in severe coxa-vara. Closed reduction with 16 mm partially threaded cannulated cancellous screw perpendicular to native neck- shaft angle. At regular follow up, mild lysis was seen around the screw and implant removal was done. Now with neck of femur non-union, walking full weight bearing with walker. The future course included excision arthroplasty or custom made prosthesis. Achrondroplasia characterised by defects in en-chondral bone formation leading to retarded cartilage growth. Literature search on peri-articular fracture management showed peadiatric disatal femur fracture fixed with percutaneous screws. In adult, neck of femur fracture is managed by percutaneous screw, DHS or prosthesis. Due to altered geometry of proximal femur DHS and Prosthesis was deferred.Early failure of CC screws in our case is due to perpendicular placement of screws which increased strain due to altered bio-mechanics. Achondroplastic dwarfs live a normal life. They are prone to peri-articular fractures because of anatomical variations. We wanted to highlight the difficulties and importance of pre-op planning and implant choice of fracture fixation in an adult achondroplasia patient.","PeriodicalId":274774,"journal":{"name":"IP International Journal of Orthopaedic Rheumatology","volume":"51 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116130811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association between vitamin D level in rheumatoid arthritis in males and females 男性和女性类风湿关节炎中维生素D水平的关系

IP International Journal of Orthopaedic Rheumatology Pub Date : 2022-07-15 DOI: 10.18231/j.ijor.2022.004

Mohita Singh, Pankaj Sharma, A. Mahajan, V. Tandon

{"title":"Association between vitamin D level in rheumatoid arthritis in males and females","authors":"Mohita Singh, Pankaj Sharma, A. Mahajan, V. Tandon","doi":"10.18231/j.ijor.2022.004","DOIUrl":"https://doi.org/10.18231/j.ijor.2022.004","url":null,"abstract":"Rheumatoid Arthritis is an autoimmune disease of unknown aetiology. The worldwide prevalence of rheumatoid arthritis is estimated to vary between 0.5 to 1.5% with geographic variation. The rationale behind relating vitamin D and RA is based on two facts. The first one is that there is evidence indicating that patients with RA have low levels of vitamin D. The second one is that the presence of vitamin D and VDR in macrophages, chondrocytes and synovial cells in the joints of these patients has also been demonstrated. The present study was designed to study the vitamin D status/ level in rheumatoid arthritis in males and females. The study was carried on 100 subjects chosen randomly with 75 females and 25 males in age group of 16 – 65 years. Their demographic data was collected. Vitamin D level, rheumatoid factor assay and ESR were analyzed. Higher level of disease activity as measured by DAS 28 score was associated with vitamin D deficiency. Females reported higher values for ESR, DAS 28 score and lower levels of vitamin D level as compared to males.Vitamin D deficiency was positively associated with increase in DAS 28 score and rheumatoid arthritis (RA). Female sex had more preponderance for RA development. Rheumatoid factor had no gender preponderance.","PeriodicalId":274774,"journal":{"name":"IP International Journal of Orthopaedic Rheumatology","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128414504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Functional and radiological outcome of autologous platelet rich plasma in chronic plantar fasciitis: A prospective study 慢性足底筋膜炎患者自体富血小板血浆的功能和放射学结果:一项前瞻性研究

IP International Journal of Orthopaedic Rheumatology Pub Date : 2022-07-15 DOI: 10.18231/j.ijor.2022.003

D. Parikh, R. Kumar, Rajarajan D, Prasanna Kumar G

{"title":"Functional and radiological outcome of autologous platelet rich plasma in chronic plantar fasciitis: A prospective study","authors":"D. Parikh, R. Kumar, Rajarajan D, Prasanna Kumar G","doi":"10.18231/j.ijor.2022.003","DOIUrl":"https://doi.org/10.18231/j.ijor.2022.003","url":null,"abstract":"Plantar fasciitis is one of the most common causes of foot pain. It results from sustained stress of weight bearing - hopping, jumping, running -which results in micro trauma to plantar fascia which further leads to plantar fasciitis. It constitutes 11% to 15% of all foot symptoms. Its prevalence is 8% to 10% in general population. It commonly affects at the age of 40 to 60 years. Recently platelet rich plasma was used in treating in degeneration, muscle and tendon injuries. Hence, the present study aimed to assess the treatment outcome of autologous platelet rich plasma injection in treatment of plantar fasciitis. In this prospective study, we enrolled 35 patients with plantar fasciitis coming to OPD or casualty. Patients satisfying inclusion criteria were selected based on consecutive sampling. 11 patients responded well to conservative management and 3 patients had loss of follow up. The different scoring systems were adopted such as VAS and AOFAS for pain assessment. The thickness of plantar fascia was determined by ultrasound technique. Autologous platelet rich plasma was prepared and the same was injected. The outcome analysis was done at 2 weeks, 3 months, and 6 months; and compared with pre injection values. From pre-injection to up to post-6 months period, the VAS reduction was statistically significant (P<0.0001). All the time interval, the AOFAS was increased which was statistically significant (P<0.001). The injection was effective in reducing the thickness of plantar fascia, which was found to be statistically significant at all the time intervals (P<0.001). Autologous PRP injection for chronic plantar fasciitis was found to be an effective treatment modality for chronic plantar fasciitis.","PeriodicalId":274774,"journal":{"name":"IP International Journal of Orthopaedic Rheumatology","volume":"68 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127978794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Landscape of Stem Cell Therapy and Research in India: Challenges and Solutions 印度干细胞治疗和研究的前景:挑战和解决方案

IP International Journal of Orthopaedic Rheumatology Pub Date : 2022-07-15 DOI: 10.18231/j.ijor.2022.010

K. Mishra, M. Khanna

引用次数: 0