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Comparison of diabetic patients' attitude and practice on medicinal herbs consumption and classical treatment in type 2 diabetes and related factors 糖尿病患者对2型糖尿病中草药消费与经典治疗的态度、行为及相关因素的比较
Endocrinology&Metabolism International Journal Pub Date : 2020-05-22 DOI: 10.15406/EMIJ.2020.08.00280
Azizi Ali, Shaheb-Hmaei Pegah
{"title":"Comparison of diabetic patients' attitude and practice on medicinal herbs consumption and classical treatment in type 2 diabetes and related factors","authors":"Azizi Ali, Shaheb-Hmaei Pegah","doi":"10.15406/EMIJ.2020.08.00280","DOIUrl":"https://doi.org/10.15406/EMIJ.2020.08.00280","url":null,"abstract":"Background: Medicinal herbs are used in traditional medicine to control and treat many diseases, including diabetes. The use of medicinal plants by diabetic patients has increased dramatically over the past decade. Methods: From diabetic patients covered by Kermanshah Diabetes Center, 51 patients were selected for each of the three groups (herbal medicine, drug therapy, and combination therapy) of type 2 diabetic patients (151 patients in total). After completing the questionnaire, their attitude and practice were compared. Effective factors were also analyzed using chi-square, t-test and one-way ANOVA. Results: Significant statistical differences were reported between the mean and standard deviation of patients' attitude toward herbal medicines in the treatment of type 2 diabetes in the herbal (17.2±0.8), medicinal (9.7±2.7) and combination group (15.4±2.3) (P<0.001). There was no significant relationship between the level of positive attitude to herbal treatment with age, sex, education level, marital status, occupation and family history of diabetes. But this relationship was significant for the duration of disease and duration of treatment (P=0.01). Cinnamon, green tea, ginger, fenugreek, nettle, and turmeric were the most commonly used medicinal herbs. Conclusions: The results of this study show that diabetic patients with the use of herbal medicine had a better attitude towards the use of herbal medicines than patients with combination or drug treatment alone. Patients with shorter duration of treatment and illness had higher attitudes and performance than herbal medicines.","PeriodicalId":272684,"journal":{"name":"Endocrinology&Metabolism International Journal","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131593255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Current topics of theory and practice for low carbohydrate diet (LCD) in diabetic patients 糖尿病患者低碳水化合物饮食(LCD)的理论与实践现状
Endocrinology&Metabolism International Journal Pub Date : 2020-04-28 DOI: 10.15406/EMIJ.2020.08.00279
H. Bando
{"title":"Current topics of theory and practice for low carbohydrate diet (LCD) in diabetic patients","authors":"H. Bando","doi":"10.15406/EMIJ.2020.08.00279","DOIUrl":"https://doi.org/10.15406/EMIJ.2020.08.00279","url":null,"abstract":"Both humans and animals generate energy by tricarboxylic acid (TCA) cycle from carbohydrates, fats and proteins. Among them, carbohydrates axis seemed to be the main route for energy production so far. In the case of diabetes, however, the restraint of glucose metabolism would be beneficial by low carbohydrate diet (LCD) or newly-introduced oral hyperglycemic agent (OHA), Sodium-Glucose Cotransporter 2 Inhibitors (SGLT2i). Author and colleagues have developed LCD movement by Japan LCD promotion association (JLCDPA). Our lectures include useful and practical 3 LCD meals, which are petite-LCD, standard-LCD and super-LCD with carbohydrate content ratio as 40%, 26% and 12%, respectively.","PeriodicalId":272684,"journal":{"name":"Endocrinology&Metabolism International Journal","volume":"46 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128688118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of quercetin from microorganism tometabolic diseases 槲皮素对微生物代谢疾病的影响
Endocrinology&Metabolism International Journal Pub Date : 2020-04-21 DOI: 10.15406/EMIJ.2020.08.00278
J. Ouyang, Li Wang
{"title":"Effects of quercetin from microorganism tometabolic diseases","authors":"J. Ouyang, Li Wang","doi":"10.15406/EMIJ.2020.08.00278","DOIUrl":"https://doi.org/10.15406/EMIJ.2020.08.00278","url":null,"abstract":"For the microorganism, quercetin has shown antibacterial, anti-biofilm and microbiota-regulating properties. Quercetin could inhibit the growth of planktonic Actinobacillus actinomycetemcomitans, Porphyromonas gingivalis, Actinomyces viscosus, Fusobacteriumnucleatum, and Actinomyces naeslundii and Helicobacter pylori.5‒7 When quercetin was used in combination with antibiotics including amoxicillin, ampicillin, cephradine, ceftriaxone, imipenem or methicillin, they were found to increase each other’s activity against Staphylococcus aureus.8 Aside from planktonic bacteria, quercetin has also been reported to inhibit biofilm development for multiple bacteria such as Enterococcus faecalis, Staphylococcus aureus, Streptococcus mutans, Escherichia coli, and Pseudomonas aeruginosa. Bacterial biofilm is multicellular aggregates enclosed in a self-created biopolymer matrix and could enable these microorganisms to evade host.Qayyum et al demonstrated that quercetin (256mg/L) could inhibit 95% biofilm formation of E. faecalis MTCC 2729 through crystal violet assay. The anti-biofilm effect of quercetin was confirmed by scanning electron microscopy (SEM) and CLSM.9 As far as Gram-negative bacterium Pseudomonas aeruginosa, Ouyang et al. reported quercetin is an effective inhibitor of quorum sensing, biofilm formation and virulence factors at a low concentration (16mg/L).","PeriodicalId":272684,"journal":{"name":"Endocrinology&Metabolism International Journal","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124981958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Thyroid: proliferative lesions in perinatal necropsies 甲状腺:围产儿尸检中的增生性病变
Endocrinology&Metabolism International Journal Pub Date : 2020-04-15 DOI: 10.15406/EMIJ.2020.08.00277
Jose Pereda-Garay
{"title":"Thyroid: proliferative lesions in perinatal necropsies","authors":"Jose Pereda-Garay","doi":"10.15406/EMIJ.2020.08.00277","DOIUrl":"https://doi.org/10.15406/EMIJ.2020.08.00277","url":null,"abstract":"Atypical thyroid lesions have been found in a routine study of perinatal necropsies. This type of lesions means Thyroid carcinoma which is suppose result of changes in the DNA along the years. In the perinatal product, DNA changes may occur during the fecundation or abnormal DNA is transmitted by one of the parents. So families should be studied. Identification of DNA changes will prove the importance of the perinatal necropsy in the family health.","PeriodicalId":272684,"journal":{"name":"Endocrinology&Metabolism International Journal","volume":"85 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115242510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neglected congenital adrenal hyperplasia presenting as recurrent abdominal pain 被忽视的先天性肾上腺增生，表现为反复腹痛
Endocrinology&Metabolism International Journal Pub Date : 2020-04-13 DOI: 10.15406/EMIJ.2020.08.00276
I. Oluwayemi, Oyebanji Ah, Omowaye Mt
{"title":"Neglected congenital adrenal hyperplasia presenting as recurrent abdominal pain","authors":"I. Oluwayemi, Oyebanji Ah, Omowaye Mt","doi":"10.15406/EMIJ.2020.08.00276","DOIUrl":"https://doi.org/10.15406/EMIJ.2020.08.00276","url":null,"abstract":"Congenital adrenal hyperplasia (CAH) is an autosomal recessive disorder with the incidence of the classic type being 1:15,000 births worldwide. It results from defective synthesis of steroid hormones because of deficiency of one of the five enzymes required for synthesis of cortisol. Cases of severe forms of CAH are often missed in developing countries where there is no program for newborn screening with many of them dying in neonatal periods. Management of the mild forms are also hindered or delayed because of superstitions, ignorance and poverty. We present an 11years old girl who presented with abnormal genital since birth and recurrent monthly lower abdominal pain of eight month duration. She had Tanner stage 4 breasts, normal female pubic hair distribution, clitoromegaly, fused scrotalized labia with urogenital sinus and absent vaginal opening. Abdominal ultrasound showed normal female reproductive organs; she had advanced bone age of 16years and elevated serum 17-hydroxyprogesterone level. She’s being worked up for possible genitoplasty.","PeriodicalId":272684,"journal":{"name":"Endocrinology&Metabolism International Journal","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124714154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Is fecal microbiota transplantation a promising strategy for type 2 diabetes mellitus? 粪便微生物群移植是治疗2型糖尿病的一个有希望的策略吗?
Endocrinology&Metabolism International Journal Pub Date : 2020-03-17 DOI: 10.15406/EMIJ.2020.08.00275
Zhong-Hua Yang
{"title":"Is fecal microbiota transplantation a promising strategy for type 2 diabetes mellitus?","authors":"Zhong-Hua Yang","doi":"10.15406/EMIJ.2020.08.00275","DOIUrl":"https://doi.org/10.15406/EMIJ.2020.08.00275","url":null,"abstract":"microbiota is tightly involved in the development of the disease. Two large metagenome-wide association studies in China and Europe revealed that individuals with T2DM were characterized by gut microbial dysbiosis, with a decrease in the abundance of some universal butyrate-producing bacteria (Roseburia), and an increase in various opportunistic pathogens (Clostridium clostridioforme).5,6 Other studies also reported significant compositional and functional alterations of microbiota in T2DM patients, compared to healthy people.7-9 The role of altered gut microbiota may not only be the consequences of T2DM, but also the causalities in developing T2DM.10 The mechanism might be related to the increase of gut permeability, microbial translocation and lipopolysaccharides (LPS), as well as the decrease of short-chain fatty acids (SCFAs), alterations of intestinal immune system, bile acids (BAs), branched chain amino acids, trimethylamine N-oxide (TMAO) and endocannabinoid system.11-15","PeriodicalId":272684,"journal":{"name":"Endocrinology&Metabolism International Journal","volume":"71 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130868590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comments on the current treatment of people with grave’s hyperthyroidism 格雷夫甲状腺机能亢进症的治疗现状
Endocrinology&Metabolism International Journal Pub Date : 2020-03-06 DOI: 10.15406/EMIJ.2020.08.00274
R. García-mayor
{"title":"Comments on the current treatment of people with grave’s hyperthyroidism","authors":"R. García-mayor","doi":"10.15406/EMIJ.2020.08.00274","DOIUrl":"https://doi.org/10.15406/EMIJ.2020.08.00274","url":null,"abstract":"Thionamide derived drugs (ATD), radioiodine (RAI) and total thyroidectomy (TT) are the main treatment options. All of them proven to be effective, but they also have important drawbacks, so it is a challenge for both doctors and patients to choose one of these treatment modalities, for this reason the main guidelines for management of GH patients recommend an active discussion between the patients and doctors regarding the benefits, risks and logistics of the different treatment modalities,2,3 always taken into consideration the patient’ preference.","PeriodicalId":272684,"journal":{"name":"Endocrinology&Metabolism International Journal","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127962961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Successful conservative management of a rare case of ruptured cornual ectopic pregnancy 1例罕见角异位妊娠破裂的成功保守治疗
Endocrinology&Metabolism International Journal Pub Date : 2020-02-24 DOI: 10.15406/EMIJ.2020.08.00272
Sreelatha S, S. Sana, P. S., Yashaswini, Shruthi K, Shridhar S
{"title":"Successful conservative management of a rare case of ruptured cornual ectopic pregnancy","authors":"Sreelatha S, S. Sana, P. S., Yashaswini, Shruthi K, Shridhar S","doi":"10.15406/EMIJ.2020.08.00272","DOIUrl":"https://doi.org/10.15406/EMIJ.2020.08.00272","url":null,"abstract":"Cornual pregnancy is a rare type of ectopic pregnancy with incidence of about 2-4% of all ectopic pregnancies. The mortality rate is about 2-2.5%. The diagnosis and management is challenging and frequently constitute a medical emergency. We report a case of a 33year old second gravida, para 1, living 1 with previous LSCS with 13weeks 2days period of gestation presenting to the casualty with complaints of severe pain abdomen and signs of hypovolemic shock. Ultrasound revealed gross hemoperitoneum with ruptured right adnexal gestation. Emergency laparotomy was done and cornual end was found ruptured and was sutured successfully and hemostasis achieved. Intra operative two units of packed cells was transfused. Patient was discharged stable on post-op day 7.","PeriodicalId":272684,"journal":{"name":"Endocrinology&Metabolism International Journal","volume":"136 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122778001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Interleukin-2 drives pulsatile cortisol secretion in an age-, dose- and body composition-dependent way in healthy men 在健康男性中，白细胞介素-2以年龄、剂量和身体成分依赖的方式驱动搏动性皮质醇分泌
Endocrinology&Metabolism International Journal Pub Date : 2020-02-24 DOI: 10.15406/emij.2020.08.00273
J. Veldhuis
{"title":"Interleukin-2 drives pulsatile cortisol secretion in an age-, dose- and body composition-dependent way in healthy men","authors":"J. Veldhuis","doi":"10.15406/emij.2020.08.00273","DOIUrl":"https://doi.org/10.15406/emij.2020.08.00273","url":null,"abstract":"","PeriodicalId":272684,"journal":{"name":"Endocrinology&Metabolism International Journal","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126484447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analysis of hematological parameters in patients with ischemic stroke 缺血性脑卒中患者血液学指标分析
Endocrinology&Metabolism International Journal Pub Date : 2020-02-12 DOI: 10.15406/EMIJ.2020.08.00271
S. Sharif
{"title":"Analysis of hematological parameters in patients with ischemic stroke","authors":"S. Sharif","doi":"10.15406/EMIJ.2020.08.00271","DOIUrl":"https://doi.org/10.15406/EMIJ.2020.08.00271","url":null,"abstract":"Background: Hematological parameters are major indicator of ischemic stroke. Hematological parameters and stroke incidence have not been investigated in local population. Objective: The present study was designed to assess whether hematological parameters play an important role in ischemic stroke patients. Methodology: For this purpose a cross-sectional study was done at Services hospital, Lahore from January 2013 to August 2013. A total of 150subjects were enrolled and divided into two groups, control (n=50) and ischemic stroke subjects (n=100). Data regarding risk factors was collected through questionnaire. Their hematological parameters such as WBCs count, RBCs count, haemoglobin concentration, HCT, MCV, MCH and PLT count were assessed by hematology analyzer. Statstical analysis was done by using SPSS (version 13). Result: Mean age of control and ischemic stroke group was 61.40y±1.33 and 63.8y±1.36 respectively with non-significant difference between the groups. Among the ischemic stroke subjects, 73% of the subjects were suffering from hypertension, 53% reported diabetes, 41% had heart disease, 39% had family history of stroke, 32% were smokers and 46% use high cholesterol food. The WBCs count, MCV, MCH and HCT were found significantly higher in ischemic stroke subjects when compared with control group while the significant decrease was observed in RBCs count and hemoglobin concentration. PLT count increased in ischemic stroke subjects as compared to control group. Conclusion: It was concluded that in ischemic stroke patients hematological parmeters were greately altered.","PeriodicalId":272684,"journal":{"name":"Endocrinology&Metabolism International Journal","volume":"164 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116294652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
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