Endocrinology&Metabolism International Journal最新文献_第3页

Contraception & covid - 19 避孕与covid - 19

Endocrinology&Metabolism International Journal Pub Date : 2020-10-15 DOI: 10.15406/EMIJ.2020.08.00290

M. Belardo, Bárbara De Nardo, Malena María Cavanna

引用次数: 1

Brain Catastrophe presented with endocrine disruption 脑灾难表现为内分泌紊乱

Endocrinology&Metabolism International Journal Pub Date : 2020-09-30 DOI: 10.15406/EMIJ.2020.08.00289

S. AlJadir

引用次数: 0

Endocrine care of transgender people: detransitions 变性人的内分泌护理:去变性

Endocrinology&Metabolism International Journal Pub Date : 2020-08-31 DOI: 10.15406/EMIJ.2020.08.00288

R. García-mayor

引用次数: 0

Perspective of the β-blockers for the patients with diabetes and heart failure β受体阻滞剂在糖尿病合并心力衰竭患者中的应用前景

Endocrinology&Metabolism International Journal Pub Date : 2020-08-31 DOI: 10.15406/EMIJ.2020.08.00287

H. Bando

引用次数: 0

Covid-19 and endocrinology – intersections: a review of current knowledge on physiopathological associations Covid-19和内分泌学的交叉点:对当前生理病理关联知识的回顾

Endocrinology&Metabolism International Journal Pub Date : 2020-08-25 DOI: 10.15406/emij.2020.08.00286

L. R. Santos, Ricardo Baer Filho, Thais Amanda Frank de Almeida Alves, Matheus Budahazi Jardine, M. Duarte

{"title":"Covid-19 and endocrinology – intersections: a review of current knowledge on physiopathological associations","authors":"L. R. Santos, Ricardo Baer Filho, Thais Amanda Frank de Almeida Alves, Matheus Budahazi Jardine, M. Duarte","doi":"10.15406/emij.2020.08.00286","DOIUrl":"https://doi.org/10.15406/emij.2020.08.00286","url":null,"abstract":"Introduction: The coronavirus-19 pandemic has reached historic dissemination, with a huge impact on physical, social and psychological well-being; understanding the pathophysiology of the disease is extremely important, as it can lead to effective therapy formulations. Objective: In this review, we will explore the current evidence surrounding the interactions of endocrine conditions and possible treatment targets. Methods: we reviewed the Medline, EMBASE and LiLACS databases using the keywords “COVID-19” or “SARS-CoV-2”, crossing them with the keywords “Obesity”, “Diabetes Mellitus”, “Vitamin D”, “ Estradiol ”,“ Testosterone ”,“ Male ”and“ Female ”; we will describe the results found in a narrative way. Results: The association of diabetes mellitus, obesity and worse prognosis of people infected with the SARS-CoV-2 virus, as well as the gender dimorphism of severity and the role of vitamin D deficiency will all be described. Conclusion: There is a riddle involving SARS-CoV-2 infection, intrinsic risk factors of the host, as well as the immune response to the infection, which is still in the solution phase; a better understanding of such mechanisms can lead to the development of highly effective treatment, as well as policies of social isolation.","PeriodicalId":272684,"journal":{"name":"Endocrinology&Metabolism International Journal","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133941226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Dysthyroidia in aircrew: flight safety impairment and aptitude management 机组人员甲状腺功能障碍:飞行安全损害与能力管理

Endocrinology&Metabolism International Journal Pub Date : 2020-07-22 DOI: 10.15406/EMIJ.2020.08.00285

Meryem Zerrik, Houda Echchachoui, Z Iloughmanez, M. Elghazi, F Bennanis, M. Chemsi

引用次数: 0

The impact of intraoperative gloves changing by the surgical team on the post operative wound infection after a Caesarean section, in a tertiary care hospital 某三级医院剖宫产术后更换手术手套对术后伤口感染的影响

Endocrinology&Metabolism International Journal Pub Date : 2020-07-15 DOI: 10.15406/EMIJ.2020.08.00284

N. Hameed, Rabia Jamshed, Muhammad Asghar Ali, Binyamin Butt, Faizan Iqbal, Saira Rashid

{"title":"The impact of intraoperative gloves changing by the surgical team on the post operative wound infection after a Caesarean section, in a tertiary care hospital","authors":"N. Hameed, Rabia Jamshed, Muhammad Asghar Ali, Binyamin Butt, Faizan Iqbal, Saira Rashid","doi":"10.15406/EMIJ.2020.08.00284","DOIUrl":"https://doi.org/10.15406/EMIJ.2020.08.00284","url":null,"abstract":"Background:Cesarean delivery is a major obstetrical surgical procedure aiming to save the lives of mothers and fetuses. Cesarean deliveries were initially performed to separate the mother and the fetus in an attempt to save the fetus of a moribund patient. Access to nonmedical interventions during labor, such as continuous support during labor and delivery, should be increased. The safe practice during cesarean can provide the protection from infection. Objective:To compare the outcome with changing gloves intra-operatively by entire team versus standard practice (no changing gloves) during cesarean section Material & methods: study design:Randomized controlled trial. Setting:Department of Obstetrics & Gynaecology, Shalamar Hospital Lahore for 6months. Data collection:After meeting the inclusion criteria 160females were enrolled. Then females were randomly divided into two groups. Group A females operated with changing gloves of entire team and group B operated with no changing gloves. During ward follow-up, females were evaluated for febrile morbidity. At the time of stiches removal wound infection was observed. All the collected data was entered and analyzed on SPSS version 21. Results:The mean age of females was 29.06±6.79years, the mean gestational age at delivery was 38.88±1.47weeks. In changing gloves group the wound infection was found in 4(5.0%) females while in no changing gloves group the wound infection was found in 15(18.8%) females (p-value=0.013). Conclusion:The adopting changing gloves practice by entire team during cesarean section showed better outcome in terms of wound infection and febrile morbidity than no changing glove practice.","PeriodicalId":272684,"journal":{"name":"Endocrinology&Metabolism International Journal","volume":"67 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126034081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Water preloading before main meals as a strategy to treat adult patients with overweight or obesity 正餐前预补水作为治疗成人超重或肥胖患者的策略

Endocrinology&Metabolism International Journal Pub Date : 2020-06-30 DOI: 10.15406/EMIJ.2020.08.00283

R. García-mayor

{"title":"Water preloading before main meals as a strategy to treat adult patients with overweight or obesity","authors":"R. García-mayor","doi":"10.15406/EMIJ.2020.08.00283","DOIUrl":"https://doi.org/10.15406/EMIJ.2020.08.00283","url":null,"abstract":"One potential strategy to reduce meal energy intake is to modify the individual perception of fullness prior to eating by the use of preload of water. The effect of water overload on weight loss can not only be attributed to an early feeling of satiety but also increases the energy expenditure. Boshmann et al,5 observed that drinking 500ml of water increases metabolic rate by 30% in both women and men, they calculate that increasing water ingestion by 1.5liters would increase daily energy expenditure by approximately 200Kj. They estimated that over 1yr energy expenditure would increase by 73,000Kj (17,400Kcal), the energy content of 2.4Kg adipose tissue. The fact that the treatment with beta-adrenoreceptor blocker agents substantially attenuated the water-induced increase in metabolic rate suggested that increase in metabolic rate with water is related to sympathetic activation and increased stimulation of beta-adrenergic receptors. Another study by the same group of researchers,6 exclude volumerelated effects or gastric distension as the mediator of the thermogenic response to water drinking, they hypothesize the existence of a portal osmoreceptor, most likely an ion channel.","PeriodicalId":272684,"journal":{"name":"Endocrinology&Metabolism International Journal","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114183777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

High risk of psychological disorders: anxiety and depression in adolescent girls with polycystic ovary syndrome 心理障碍的高风险:多囊卵巢综合征青春期女孩的焦虑和抑郁

Endocrinology&Metabolism International Journal Pub Date : 2020-06-29 DOI: 10.15406/EMIJ.2020.08.00282

Mohadetheh Moulana, Crystal S. Lim, Anju P Sukumaran

{"title":"High risk of psychological disorders: anxiety and depression in adolescent girls with polycystic ovary syndrome","authors":"Mohadetheh Moulana, Crystal S. Lim, Anju P Sukumaran","doi":"10.15406/EMIJ.2020.08.00282","DOIUrl":"https://doi.org/10.15406/EMIJ.2020.08.00282","url":null,"abstract":"Study objective: This study is aimed to assess the prevalence of psychological disorders among different racial/ethnic group of normal weight and overweight adolescents with polycystic ovary syndrome (PCOS)from a state in southeastern US. Design, setting, and participants: The data of 157,459 adolescents were collected through “the Patient Cohort Explorer” system at the University of Mississippi Medical Center (UMMC) from January 2013 to December 2019.Unidentified patients were searched with diagnosis code for PCOS, age, race/ethnicity, and associated diagnosis including weight gain, anxiety, depression, ADHD, and behavioral concerns. Interventions: None. Main outcome measures: Prevalence of PCOS and psychological disorders. Results: A total of 712 adolescents with PCOS were diagnosed in clinics during the period of study. Collected data indicated that prevalence of PCOS in adolescents seen in clinics was less than 1% with no significant difference by race or ethnicity. Almost 45% of patients suffered from one or more psychological disorders. (Anxiety: 18%, Depression: 16%, ADHD: 9%). Conclusions: Results from this study provide the first evidence of prevalence of PCOS and psychological disorders in adolescents with PCOS in a southern state. Our findings of a high prevalence of psychological disorders suggest that early screening for mental health symptoms must be considered during primary care clinical assessment of adolescents with PCOS. Left undiagnosed and/or untreated, chronic anxiety and depression may exacerbate mental health issues in this vulnerable population.","PeriodicalId":272684,"journal":{"name":"Endocrinology&Metabolism International Journal","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122456491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Metformin-Mg2+ adjunct therapy synergistically modulates insulin and PDX-1 gene signatures in STZ-NAD induced diabetic model 二甲双胍- mg2 +辅助治疗可协同调节STZ-NAD诱导的糖尿病模型中的胰岛素和PDX-1基因特征

Endocrinology&Metabolism International Journal Pub Date : 2020-05-25 DOI: 10.15406/EMIJ.2020.08.00281

Oluwaseun Fapohunda, Femi Abiola Ogunleye, T. H. Ogunwa, Idowu Olaposi Omotuy, Titilola Titilayoaderonke Samuel, K. O. Inyang, Hellen Omolade Adejube, J. Saliu

{"title":"Metformin-Mg2+ adjunct therapy synergistically modulates insulin and PDX-1 gene signatures in STZ-NAD induced diabetic model","authors":"Oluwaseun Fapohunda, Femi Abiola Ogunleye, T. H. Ogunwa, Idowu Olaposi Omotuy, Titilola Titilayoaderonke Samuel, K. O. Inyang, Hellen Omolade Adejube, J. Saliu","doi":"10.15406/EMIJ.2020.08.00281","DOIUrl":"https://doi.org/10.15406/EMIJ.2020.08.00281","url":null,"abstract":"Diabetes mellitus (DM) is a multi-factorial debilitating disorder of metabolism, usually due to a combination of hereditary and environmental causes, resulting in abnormally high blood sugar levels (hyperglycemia) as a result of defects in either insulin secretion or insulin action in the body. DM is usually accompanied by hypomagnesemia. This study was aimed at investigating the effect of oral magnesium supplementation on pancreatic gene expression of insulin and PDX-1 in type-2 streptozotocin-nicotinamide induced Sprague dawley diabetic rats. A total of 24Sprague dawleyrats (Four groups of six rats each), were used for this study; Group 1: Normal rats (CONTROL) given distilled water for 4weeks; Group 2: Metformin + Magnesium treated rats (DMM) orally given 100mg/kg and 1000mg/kg body weight respectively for 4weeks; Group 3: Metformin treated diabetic rats (DM), orally given 100mg/kg body weight for 4weeks; Group 4: Diabetic untreated control rats (DU) given distilled water for 4weeks. Measured data were analyzed statistically. The result revealed that there was significant (p<0.05) increase in the feed and water intake of the treated rats but the metformin-magnesium supplement treated group showed more increase when compared with only metformin treated group. PDX-1 and insulin gene expression levels were significantly (p<0.05) higher in the control when compared with all the diabetic groups. However, PDX-1 and insulin mRNA levels were significantly (p<0.05) higher in DMM, when compared with DM. DMM showed improvements when compared with DM which suggests magnesium supplementation as an adjunct therapy with metformin may help inthe regeneration of the beta cells of the pancreas.","PeriodicalId":272684,"journal":{"name":"Endocrinology&Metabolism International Journal","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130866982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2