The Open Anesthesiology Journal最新文献_第3页

Adjustable Horseshoe Headrest as a Positioning Adjunct in Airway Management for a Giant Occipital Encephalocele 可调节马蹄形头枕在巨大枕部脑膨出气道管理中的定位辅助作用

The Open Anesthesiology Journal Pub Date : 2017-08-29 DOI: 10.2174/1874321801711010083

H. R. Karim, Muhammad Yunus, A. Barman, S. Kakati, Samarjit Dey

引用次数: 1

Sleep disordered breathing may signal laryngomalacia 睡眠呼吸紊乱可能是喉软化症的信号

The Open Anesthesiology Journal Pub Date : 2017-08-21 DOI: 10.2174/1874321801711010068

C. Clark, D. DiSalvo, Jansie Prozesky, M. Carr

引用次数: 0

The GlideScope Video Laryngoscope: A Narrative Review 滑翔机视频喉镜:述评

The Open Anesthesiology Journal Pub Date : 2017-08-15 DOI: 10.2174/1874321801711010048

D. Doyle

引用次数: 8

Appropriate Use of Oxygen Delivery Devices 正确使用供氧装置

The Open Anesthesiology Journal Pub Date : 2017-07-31 DOI: 10.2174/1874321801711010035

S. Batool, R. Garg

引用次数: 4

Isoflurane but not Fentanyl Causes Apoptosis in Immature Primary Neuronal Cells 异氟醚而非芬太尼引起未成熟的原代神经元细胞凋亡

The Open Anesthesiology Journal Pub Date : 2017-07-31 DOI: 10.2174/1874321801711010039

M. Berns, Anika Wolter, C. Bührer, S. Endesfelder, T. Kerner

{"title":"Isoflurane but not Fentanyl Causes Apoptosis in Immature Primary Neuronal Cells","authors":"M. Berns, Anika Wolter, C. Bührer, S. Endesfelder, T. Kerner","doi":"10.2174/1874321801711010039","DOIUrl":"https://doi.org/10.2174/1874321801711010039","url":null,"abstract":"Received: December 29, 2016 Revised: March 03, 2017 Accepted: March 09, 2017 Abstract: Background: Anaesthetics are widely used in new-borns and preterm infants, although it is known that they may adversely affect the developing brain. Objective: We assessed the impact of the volatile anaesthetic, isoflurane, and the intravenous analgesic, fentanyl, on immature and mature embryonic neuronal cells. Methods: Primary neuronal cultures from embryonic rats (E18) cultured for 5 (immature) or 15 days (mature) in vitro (DIV), respectively, were exposed to isoflurane (1.5 Vol.%) or fentanyl (0.8 200 ng/ml) for 24 hours. Experiments were repeated in the presence of the γamino butyric acid-A (GABAA) receptor antagonists, bicuculline or picrotoxin (0.1 mmol/l), or the pancaspase inhibitor zVAD-fmk (20 nmol/l). Cell viability was assessed by methyltetrazolium (MTT) metabolism or lactate dehydrogenase (LDH) release. Results: Isoflurane reduced cell viability significantly in primary neuronal cells cultured for 5 DIV (Δ MTT -28 ±13%, Δ LDH +143 ±15%). Incubation with bicuculline, picrotoxin or zVAD-fmk protected the cells mostly from isoflurane toxicity. After 15 DIV, cell viability was not reduced by isoflurane. Viability of primary neurons cultured for 5 DIV did not change with fentanyl over the wide range of concentrations tested. Conclusion: Immature primary neurons may undergo apoptosis following exposure to isoflurane but are unaffected by fentanyl. Mature primary neurons were not affected by isoflurane exposure.","PeriodicalId":272376,"journal":{"name":"The Open Anesthesiology Journal","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114814759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Perioperative Hemodynamic Changes During Video-Assisted Thoracoscopic Decortication for empyema 胸腔镜胸腔镜下脓胸去皮术围术期血流动力学变化

The Open Anesthesiology Journal Pub Date : 2017-07-31 DOI: 10.2174/1874321801711010088

Fang-Ting Chen, A. Chou, Chun-Yu Chen, Pei‐Chi Ting, Ming‐Wen Yang, Chun-Hui Lee, Yun-Hui Teng

引用次数: 0

Clinical Pearls in Anaesthesia for Pleurectomy/Decortication for Malignant Mesothelioma 恶性间皮瘤胸膜切除术/去皮术麻醉中的临床珍珠

The Open Anesthesiology Journal Pub Date : 2017-06-30 DOI: 10.2174/1874321801711010029

S. Shah, Itee Chowdhury, Laleng Mawia Darlong, P. Goyal, A. Kansal

引用次数: 0

Should Low Central Venous Pressure Be Maintained during Liver Transplantation 肝移植过程中中心静脉压是否应保持较低

The Open Anesthesiology Journal Pub Date : 2017-03-20 DOI: 10.2174/1874321801711010017

Jong Hae Kim

{"title":"Should Low Central Venous Pressure Be Maintained during Liver Transplantation","authors":"Jong Hae Kim","doi":"10.2174/1874321801711010017","DOIUrl":"https://doi.org/10.2174/1874321801711010017","url":null,"abstract":"Low central venous pressure, which indirectly reflects free hepatic venous pressure, is maintained during hepatic resection surgery to reduce intraoperative blood loss by facilitating hepatic venous outflow. However, whether the low central venous pressure protocol established for non-transplant hepatobiliary surgery should be generalized to liver transplantation is controversial because patients with cirrhosis have decreased portal and hepatic venous blood flow and vulnerability to renal failure. However, consistent with observations from hepatic resection surgeries, lowering central venous pressure during the preanhepatic phase significantly reduces blood loss and transfusion volume. Conversely, inherent study limitations and different study designs have yielded different results in terms of renal dysfunction. Although hepatic venous outflow promoted by lowering blood volume seems to facilitate a liver graft to accommodate portal blood flow increased by portal hypertension-induced splanchnic vasodilatation, the association between low central venous pressure and reduced incidence of portal hyperperfusion injury has not been demonstrated. Stroke volume variation predicts fluid responsiveness better than central venous pressure, but it has not been associated with a greater clinical benefit than central venous pressure to date. Therefore, the safety of maintaining low central venous pressure during liver transplantation has not been verified, and further randomized controlled studies are warranted to establish a fluid management protocol for each phase of liver transplantation to reduce intraoperative blood loss and transfusion rate, thereby maintaining liver graft viability. In conclusion, low central venous pressure reduces intraoperative blood loss but does not guarantee renoprotection or graft protection.","PeriodicalId":272376,"journal":{"name":"The Open Anesthesiology Journal","volume":"53 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127349625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Horner Syndrome After Lumbar Epidural Analgesia in a Patient with Ehlers-danlos Syndrome ehers -danlos综合征患者腰硬膜外镇痛后的Horner综合征

The Open Anesthesiology Journal Pub Date : 2017-02-16 DOI: 10.2174/1874321801711010012

X. Kong, T. Alston, Jingping Wang

引用次数: 1

The Confounding Effect of Assessor Ethnicity on Subjective Pain Reporting in Women 评估者种族对女性主观疼痛报告的混淆效应

The Open Anesthesiology Journal Pub Date : 2017-01-31 DOI: 10.2174/1874321801711010001

J. Vigil, Patrick Coulombe, Lauren N. Rowell, Chance R. Strenth, Eric S. Kruger, Joe Alcock, K. Venner, Sarah S. Stith, Joseph E. Lamendola

{"title":"The Confounding Effect of Assessor Ethnicity on Subjective Pain Reporting in Women","authors":"J. Vigil, Patrick Coulombe, Lauren N. Rowell, Chance R. Strenth, Eric S. Kruger, Joe Alcock, K. Venner, Sarah S. Stith, Joseph E. Lamendola","doi":"10.2174/1874321801711010001","DOIUrl":"https://doi.org/10.2174/1874321801711010001","url":null,"abstract":"The current study examines how subjective pain reporting is influenced by the concordant and discordant nature of the ethnic identities of pain expressers (participants) and pain assessors (experimenters). Three discomfort conditions that varied in stimuli intensity (Study 1: mild pain; Study 2: severe pain), and distraction components (Study 3) were used to assess whether pain intensity and tolerance reporting differ with the ethnic identification of the participant and the experimenter. Specifically, 87 Hispanic and 74 Non-Hispanic White (NHW) women (18–51 yrs., Mage = 20.0, SD = 4.3) underwent a cold pressor pain task (CPT) after engaging in minimal procedural interactions with one of the 22 research experimenters (47% Hispanic, 42% females). The procedural interactions with the experimenters included only consenting and instructions, with no interaction between experimenter and participant during the actual CPT. Random-effects models showed that between the 0% and 18% of the variance in pain sensitivity (intensity and tolerance scores) was attributable to characteristics of the experimenters. Controlling for self-esteem, baseline pain levels, and the gender of the experimenter, Hispanic subjects showed higher pain sensitivity (as marked by lower pain tolerance and higher pain intensity scores) following interactions with an NHW rather than a Hispanic experimenter in response to the most severe pain intensity stimuli. These results question the validity of common findings of ethnic differences in pain sensitivity from studies that have not accounted for the ethnic identity of the pain assessor (and the general communicative nature of pain reporting).","PeriodicalId":272376,"journal":{"name":"The Open Anesthesiology Journal","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115101795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1