2009 IEEE SensorsPub Date : 2022-02-24DOI: 10.1016/B978-0-08-030771-8.50003-6
V. James, K. Laumas, K. Voigt, Hans R. Lindner, O. V. Dominguez, M. Lipsett, E. Jensen, L. Martini, W. Adlercreutz, M. Lippman, C. Bardin, W. Mainwaring, J. Blaquier, J. Mathieu, H. Burger, E. Milgrom, D. Kretser, M. Motta, H. D. Luca, E. Nieschlag, C. Denef, H. Rochefort, J. Findlay, F. Schröder, J. Fishman, M. Sekso, M. Forest, M. Serio, W. Staib, B. Hoffman, S. R. Stitch, H. Imura, R. Takeda, F. Labrie, J. Tresguerres, W. Ladosky, H. V. D. Molen, M. Finkelstein, A. Nimrod, Y. Mazur, B. Lunenfeld, I. Spitz, B. Eckstein
{"title":"International organizing committee","authors":"V. James, K. Laumas, K. Voigt, Hans R. Lindner, O. V. Dominguez, M. Lipsett, E. Jensen, L. Martini, W. Adlercreutz, M. Lippman, C. Bardin, W. Mainwaring, J. Blaquier, J. Mathieu, H. Burger, E. Milgrom, D. Kretser, M. Motta, H. D. Luca, E. Nieschlag, C. Denef, H. Rochefort, J. Findlay, F. Schröder, J. Fishman, M. Sekso, M. Forest, M. Serio, W. Staib, B. Hoffman, S. R. Stitch, H. Imura, R. Takeda, F. Labrie, J. Tresguerres, W. Ladosky, H. V. D. Molen, M. Finkelstein, A. Nimrod, Y. Mazur, B. Lunenfeld, I. Spitz, B. Eckstein","doi":"10.1016/B978-0-08-030771-8.50003-6","DOIUrl":"https://doi.org/10.1016/B978-0-08-030771-8.50003-6","url":null,"abstract":"","PeriodicalId":262591,"journal":{"name":"2009 IEEE Sensors","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129734604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
2009 IEEE SensorsPub Date : 2009-12-01DOI: 10.1109/ICSENS.2009.5398143
M. Yamaguchi, S. Yoshikawa, Y. Tahara, D. Niwa, Yoshikatsu Imai, V. Shetty
{"title":"Point-of-use measurement of salivary cortisol levels","authors":"M. Yamaguchi, S. Yoshikawa, Y. Tahara, D. Niwa, Yoshikatsu Imai, V. Shetty","doi":"10.1109/ICSENS.2009.5398143","DOIUrl":"https://doi.org/10.1109/ICSENS.2009.5398143","url":null,"abstract":"The objective is to develop a novel methodology to analyze cortisol levels in saliva as an index of neuroendocrine response. In order to realize a portable, rapid and hand held biosensor of cortisol, we proposed an immuno-chromatographic test-strip based biosensor consisting of a disposable test-strip and a monitor. A fabricated disposable type test-strip has a size of 5 × 1.5 × 50 mm3. In order to realize an immuno-chromatographic test-strip, a glucose oxidase (GOD)-cortisol conjugate was newly synthesized, because the speed and selectivity of immunological reactions is particularly attractive as a strategy for molecular recognition of cortisol. The synthesized molecule was identified as the GOD-cortisol conjugate by both its molecular weight and specific detection of cortisol. Three min after addition of GOD enzyme assay solution, a color change reaction at a test line was observed. The R2 value for the calibration curve of the cortisol test strip was 0.95, and the relationship between its reflectance, r, and the cortisol level was r = 0.629 (1−0.232e(−1.78 × cortisol)). The fabricated cortisol biosensor enabled us to analyze cortisol concentrations between 1 – 10 ng/ml within 25 min of dropping a cortisol solution on the test strip. Thus, it is suggested that the cortisol biosensor may possibly be used for point-of-use measurements in hospitals.","PeriodicalId":262591,"journal":{"name":"2009 IEEE Sensors","volume":"214 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2009-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131494269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
2009 IEEE SensorsPub Date : 2009-12-01DOI: 10.1109/ICSENS.2009.5398183
C. Chuang, C. Wei, Y. Hsu, Huei-Sheng Huang, F. Hsiao
{"title":"Impedance sensing of bladder cancer cells based on a single-cell-based DEP microchip","authors":"C. Chuang, C. Wei, Y. Hsu, Huei-Sheng Huang, F. Hsiao","doi":"10.1109/ICSENS.2009.5398183","DOIUrl":"https://doi.org/10.1109/ICSENS.2009.5398183","url":null,"abstract":"Differentiation of normal human bladder cell (SVHUC) between two different-grade bladder cancer cell lines (TSGH8301, grade II and TCCSUP, grade IV) was successful developed based on a dielectrophoresis (DEP) microchip with microcavity array and multilayer electrodes. Single cell could be firstly trapped in the microcavity by negative DEP force between top and middle electrodes without overlapping problem; then, the trapped cells were sensed its impedance by sweeping AC signal in between middle and bottom electrodes. As the experimental results, the impedance of higher-grade bladder cancer cells was smaller than the value of lower-grade bladder cancer cells, i.e., TCCSUP (grade IV) ≫ TSGH8301 (grade II), and the impedance of normal bladder cell was much higher than the values of both cancer cell lines. Basically, the impedances of all kinds of cell lines were decreased with the delay time measured when cells were taken out of the incubator. The largest difference of impedance between normal cells and cancer cells occurred as the delay time reached 1 hour, furthermore, the ratio of impedance between cancer cells and normal cells measured at 1 KHz and 0.2 V were 54% and 22% for TSGH8301 and TCCSUP, respectively. Consequently, the possibility of impedance measurement for evaluation of cancer cells was first proposed and investigated; moreover, the microchip provides the potential of electrical sensing for in vitro diagnosis under single cell resolution.","PeriodicalId":262591,"journal":{"name":"2009 IEEE Sensors","volume":"57 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2009-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122263171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
2009 IEEE SensorsPub Date : 2009-12-01DOI: 10.1109/ICSENS.2009.5398462
K. Okada, J. Fukuda, H. Suzuki, Satoru Ayano, Yuko Nikaido, T. Nishi, Keiko Oka
{"title":"Rapid diagnostic device for mastitis based on electrochemical detection of superoxide produced from neutrophils in fresh milk","authors":"K. Okada, J. Fukuda, H. Suzuki, Satoru Ayano, Yuko Nikaido, T. Nishi, Keiko Oka","doi":"10.1109/ICSENS.2009.5398462","DOIUrl":"https://doi.org/10.1109/ICSENS.2009.5398462","url":null,"abstract":"To identify dairy cows suffering from subclinical mastitis, we used the fact that the number of neutrophils increases in raw milk. The neutrophils, a type of white blood cells, produce superoxide (O2). Therefore, the amount of O2 produced in raw milk can be used as an indicator for mastitis. To this end, we fabricated a device consisting of thin-film threee-lectrode systems. A self-assembled monolayer (SAM) of cysteine was formed on a gold electrode and superoxide dismutase (SOD) was immobilized there. Compartments were formed with polydimethylsiloxane (PDMS) by replica molding. A preliminary test that uses xanthine oxidase (XOD) to produce O2 showed characteristic peaks originating from the production and rapid extinction of O2. When a raw milk sample obtained from a cow suffering from subclinical mastitis was injected into the device and opsonized zymosan was added to activate neutrophils, a current increase distinctly different from the background was observed, demonstrating the applicability of this device for rapid diagnosis of subclinical mastitis.","PeriodicalId":262591,"journal":{"name":"2009 IEEE Sensors","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2009-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127806562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
2009 IEEE SensorsPub Date : 2009-12-01DOI: 10.1109/ICSENS.2009.5398450
Chun-Mao Chen, M. Yeh, Y. Chuang, Che-Hsin Lin, C-S Chien
{"title":"A novel microchip system integrated with gold nano-electrode ensemble for electrochemical determination of hyaluronic acid","authors":"Chun-Mao Chen, M. Yeh, Y. Chuang, Che-Hsin Lin, C-S Chien","doi":"10.1109/ICSENS.2009.5398450","DOIUrl":"https://doi.org/10.1109/ICSENS.2009.5398450","url":null,"abstract":"This paper proposes an innovative microfluidic device for hyaluronic acid (HA) extraction and electrochemical detection utilizing PMMA based microchip that integrated with gold nanoelectrode ensemble (GNEE). Gold nanoelectrode ensemble is fabricated using electroless deposition in a thin polycarbonate (PC) film and then directly bonded onto the PMMA substrate for high performance electrochemical detection. In the study, microwave is firstly used to decrease the interference of protein on the working electrode, and then electrostatic force is used to separate and extract HA in the rat serum sample. The used of GNEE electrodes in the microchip not only enhances the signal but also decreases the background noises, resulting a high detection limit of 0.1 mg/mL for HA, and showing good linear responses in the concentration range of 10 mg/mL−0.1 mg/mL (R2=0.956). The proposed microchip device provides a fast detection method for hyaluronic acid analysis.","PeriodicalId":262591,"journal":{"name":"2009 IEEE Sensors","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2009-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127006196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
2009 IEEE SensorsPub Date : 2009-12-01DOI: 10.1109/ICSENS.2009.5398566
R. Binions, A. Afonja, S. Dungey, D. Lewis, I. Parkin, David E. Williams
{"title":"Discrimination effects in zeolite modified metal oxide semiconductor gas sensors","authors":"R. Binions, A. Afonja, S. Dungey, D. Lewis, I. Parkin, David E. Williams","doi":"10.1109/ICSENS.2009.5398566","DOIUrl":"https://doi.org/10.1109/ICSENS.2009.5398566","url":null,"abstract":"The use of zeolites to enhance the response and discriminating power of solid state metal oxide semiconductor gas sensors is demonstrated. Thick film sensors were prepared by screen printing layers of chromium titanium oxide (CTO) with various zeolites as over-layers. The sensors gas response was tested against two similar gases; ethanol and isopropyl alcohol. The modified sensors effectively discriminated between the two gases. An understanding of this discriminating behaviour is elucidated through computer modelling of diffusion and reaction processes occurring in the zeolite transformation layer and sensor element. Our analysis suggests that the discriminating behaviour is the result of a size and shape selective catalysis.","PeriodicalId":262591,"journal":{"name":"2009 IEEE Sensors","volume":"194 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2009-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116688025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
2009 IEEE SensorsPub Date : 2009-12-01DOI: 10.1109/ICSENS.2009.5398184
Chun-Mao Chen, M. Yeh, Chia-Yen Lee, Y. Chuang, Che-Hsin Lin
{"title":"A hydrogen evolution reaction determination system integrated high electrocatalyst palladium nano-electrode ensemble","authors":"Chun-Mao Chen, M. Yeh, Chia-Yen Lee, Y. Chuang, Che-Hsin Lin","doi":"10.1109/ICSENS.2009.5398184","DOIUrl":"https://doi.org/10.1109/ICSENS.2009.5398184","url":null,"abstract":"The aim of this work is to develop a high electrocatalyst system for hydrogen evolution utilizing palladium electrode ensemble (Pd-NEE). The work proposes a novel fabrication process to fabricate Pd-NEE using electroless deposition of Pd in a thin porous polycarbonate (PC) film for high performance electrochemical detection. Scanning electron microscopy (SEM) in conjunction with energy dispersive X-ray spectroscopy (EDS) are used to characterize the morphology and composition of Pd-NEE. It shows the best performance for hydrogen evolution reaction on Pd-NEE than other electrodes including bulk Pd, bulk Au and gold nanoelectrode ensemble. The Pd-NEE has a linear peak current response of the removal of adsorbed hydrogen over the tested sample concentration range. The effect of scan rate for voltammetric analysis is investigated. It is found that peak currents decrease as the scan rate from 0.5–0.05 V/s, but increase as the scan rate is lower than 0.05 V/s. It is demonstrated that hydrogen absorption and desorption on Pd-NEE is faster than that on other materials. A high electrocatalyst system is developed for hydrogen evolution reaction (HER).","PeriodicalId":262591,"journal":{"name":"2009 IEEE Sensors","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2009-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122337895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
2009 IEEE SensorsPub Date : 2009-12-01DOI: 10.1109/ICSENS.2009.5398416
M. Cole, J. Gardner, Z. Rácz, S. Pathak, Á. Guerrero, L. Muoz, G. Carot, T. Pearce, J. Challiss, D. Markovic, B. Hansson, S. Olsson, L. Kubler, J. Gardeniers, N. Dimov, W. Bula
{"title":"Biomimetic insect infochemical communication system","authors":"M. Cole, J. Gardner, Z. Rácz, S. Pathak, Á. Guerrero, L. Muoz, G. Carot, T. Pearce, J. Challiss, D. Markovic, B. Hansson, S. Olsson, L. Kubler, J. Gardeniers, N. Dimov, W. Bula","doi":"10.1109/ICSENS.2009.5398416","DOIUrl":"https://doi.org/10.1109/ICSENS.2009.5398416","url":null,"abstract":"By exploiting recent advances in both our understanding of pheromone biosynthesis pathways and the detection of molecules in the insect nervous system, we are developing a novel communication system based on functional equivalents of the cellular, sub-cellular and molecular biological machinery. This will form the basis of a new branch of information technology employing infochemical ligands for communication over space and time. In order to achieve this objective, both chemical signal generation and reception are replicated by taking a systematic approach that implements reaction steps as biosynthetic modules, which are then hierarchically integrated as a technological solution towards realising `infochemical communication'.","PeriodicalId":262591,"journal":{"name":"2009 IEEE Sensors","volume":"76 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2009-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127081724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
2009 IEEE SensorsPub Date : 2009-12-01DOI: 10.1109/ICSENS.2009.5398563
P. Lin, Yen-I Chou, Wen-Chau Liu, Chieng-Chi Tung, Huey-Ing Chen
{"title":"Ethanol vapor sensors based on carboxyl- alkanethiolate self-assembled monolayers modified Au/GaAs Schottky diodes","authors":"P. Lin, Yen-I Chou, Wen-Chau Liu, Chieng-Chi Tung, Huey-Ing Chen","doi":"10.1109/ICSENS.2009.5398563","DOIUrl":"https://doi.org/10.1109/ICSENS.2009.5398563","url":null,"abstract":"Ethanol vapor sensors based on carboxyl-alkanethiolate self-assembled monolayers (SAMs) modified Au/GaAs Schottky diodes were fabricated in this work. The adsorption and arrangement of SAMs with different carbon number on the Au(111) surface were studied by using cyclic voltammetry (CV). Moreover, effects of ethanol vapor concentration and operating temperature on sensing performances were investigated.","PeriodicalId":262591,"journal":{"name":"2009 IEEE Sensors","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2009-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127084749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
2009 IEEE SensorsPub Date : 2009-10-26DOI: 10.1109/ICSENS.2009.5398537
T. Prodromakis, K. Michelakis, T. Zoumpoulidis, R. Dekker, C. Toumazou
{"title":"Biocompatible encapsulation of CMOS based chemical sensors","authors":"T. Prodromakis, K. Michelakis, T. Zoumpoulidis, R. Dekker, C. Toumazou","doi":"10.1109/ICSENS.2009.5398537","DOIUrl":"https://doi.org/10.1109/ICSENS.2009.5398537","url":null,"abstract":"One of the most challenging design aspects of chemical sensors is the isolation of the non-sensitive areas from the sensed medium. This becomes particularly critical in applications where the sensors are part of an implantable platform, restricting the available options to those using biocompatible materials. Parylene has been extensively used to coat pacemakers as it demonstrates excellent chemical, electrical and thermal stability. In this work, we have utilized parylene to encapsulate CMOS-based chemical sensors bonded on a cartridge, while the sensing area has been exposed by laser ablation and sonication. Measured results demonstrate improved electrical isolation than previously reported techniques.","PeriodicalId":262591,"journal":{"name":"2009 IEEE Sensors","volume":"65 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2009-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124717015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}