The Korean Journal of Cytopathology最新文献_第3页

The Diagnostic Accuracy of Fine Needle Aspiration Cytology and the Diagnostic Usefulness of Galectin-3 Immunostaining for the Follicular Variant of Papillary Thyroid Carcinoma 细针穿刺细胞学对滤泡型甲状腺乳头状癌的诊断准确性及半凝集素-3免疫染色的诊断价值

The Korean Journal of Cytopathology Pub Date : 2008-09-01 DOI: 10.3338/KJC.2008.19.2.160

C. Jung, J. Shin, Hyun Seung Lee, Ahwon Lee, E. Jung, Yeong-jin Choi, Kyo‐Young Lee

{"title":"The Diagnostic Accuracy of Fine Needle Aspiration Cytology and the Diagnostic Usefulness of Galectin-3 Immunostaining for the Follicular Variant of Papillary Thyroid Carcinoma","authors":"C. Jung, J. Shin, Hyun Seung Lee, Ahwon Lee, E. Jung, Yeong-jin Choi, Kyo‐Young Lee","doi":"10.3338/KJC.2008.19.2.160","DOIUrl":"https://doi.org/10.3338/KJC.2008.19.2.160","url":null,"abstract":"The cytologic diagnosis of the follicular variant of papillary thyroid carcinoma (FVPTC) has become one of the common causes of false negative diagnoses when performing fine needle aspiration cytology (FNAC) of the thyroid gland. We retrospectively reviewed all the aspirates for which a diagnosis of FVPTC had been made based on the surgically excised specimens, regardless of the cytologic diagnosis. 145 FNACs was performed in 135 patients. The cytologic diagnoses were categorized as 2 unsatisfactory specimens (1.4%), 16 benign (11.0%), 49 atypical (33.8%) and 78 malignant lesions (53.8%). The tumor cells consistently showed significant nuclear overlapping, irregular nuclei and fine chromatin in all cases; however, nuclear grooves and inclusions were scarce. Galectin-3 immunostaining was performed on the cell blocks of 65 cases and this was positive for 45 cases (69.2%). The results of our study demonstrate that the determination of minimal cytologic criteria is needed to raise the sensitivity of detecting FVPTC by FNAC, and galectin-3 immunostaining is useful to make decisions on the surgical treatment of cytologically atypical thyroid nodules.","PeriodicalId":261069,"journal":{"name":"The Korean Journal of Cytopathology","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128477008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Touch Imprint Cytology of Adenomatoid Tumor of the Tunica Albuginea - A Case Report - 白膜腺瘤样瘤的触摸印迹细胞学分析1例

The Korean Journal of Cytopathology Pub Date : 2008-03-01 DOI: 10.3338/KJC.2008.19.1.47

Jong Im Lee

{"title":"Touch Imprint Cytology of Adenomatoid Tumor of the Tunica Albuginea - A Case Report -","authors":"Jong Im Lee","doi":"10.3338/KJC.2008.19.1.47","DOIUrl":"https://doi.org/10.3338/KJC.2008.19.1.47","url":null,"abstract":"Adenomatoid tumor is a benign neoplasm of a mesothelial origin, and it usually occurs in the reproductive organs, especially in the epididymis. The author experienced a case of adenomatoid tumor involving the tunica albuginea and testicular parenchyme without any evidence of epididymis involvement. The patient was a 36-year-old man with a painless scrotal mass that he had experienced for 2 months, and this mimicked testicular neoplasia, including metastatic carcinoma, or other benign lesions. The imprint cytology of the tumor showed a hypocellular smear with mainly arranged cells in cohesive monolayered clusters along with occasional singly dispersed cells and naked nuclei in a clean background. The cellular clusters formed vague glandular and cord-like structures. The tumor cells were large polygonal to columnar cells with a relatively monomorphic appearance. The nuclei were oval to round shape and they showed vesicular, fine chromatin and inconspicuous nucleoli. The cytoplasm was moderate to abundant, and it contained fine vacuoles in some tumor cells. Mitoses and cellular pleomorphism were not present. Awareness of the cytologic finding of this lesion is necessary to screen or differentiate a testicular or paratesticular mass before and/or during surgery because the cytology may be useful as a diagnostic tool. Pathologists should be aware of the cytologic features of common lesions in this anatomic region so as to avoid performing aggressive and unnecessary surgical procedures.","PeriodicalId":261069,"journal":{"name":"The Korean Journal of Cytopathology","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124004787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Fine Needle Aspiration Cytology of Subacute Granulomatous Thyroiditis: A Clinico-Cytological Review of 10 Cases with Immunocytochemical Analysis. 亚急性甲状腺肉芽肿性炎细针吸细胞学:10例免疫细胞化学分析的临床细胞学回顾。

The Korean Journal of Cytopathology Pub Date : 2008-03-01 DOI: 10.3338/KJC.2008.19.1.27

Do Kyung Kim, J. Pyo, Jong-Pil Park, Lian-hua Jin, Woo Hee Jeong, E. Son, S. Hong

{"title":"Fine Needle Aspiration Cytology of Subacute Granulomatous Thyroiditis: A Clinico-Cytological Review of 10 Cases with Immunocytochemical Analysis.","authors":"Do Kyung Kim, J. Pyo, Jong-Pil Park, Lian-hua Jin, Woo Hee Jeong, E. Son, S. Hong","doi":"10.3338/KJC.2008.19.1.27","DOIUrl":"https://doi.org/10.3338/KJC.2008.19.1.27","url":null,"abstract":"Although subacute granulomatous thyroiditis(SGT) is usually diagnosed clinically, papillary carcinoma or other thyroid conditions must be considered in the differential diagnosis. We retrospectively reviewed the clinical and fine-needle aspiration(FNA) cytologic findings seen in 10 SGT cases to decide what are the most reliable cytologic findings and the most helpful molecular tools for reaching a confident cytologic diagnosis. The most representative smear slides were retrieved to perform immunocytochemistry for cytokeratin 19(CK19) and Ret protein. Five papillary carcinomas(PTCs) were included as controls. The constant and typical cytologic findings of SGT were multinucleated giant cells(MGCs) (100%), epithelioid granulomas(90%), an inflammatory dirty background(90%) and plump transformed follicular cells(80%) without fire-flare cells, oncocytic cells or transformed lymphocytes. The immunoreactivities for CK19(37.5%) and Ret(10%) of the follicular cells of SGT were less than those(CK19 and Ret:100%) of PTC. CK19 immunoreactivity of the MGCs was seen in only one case of PTC. There was no significant difference between CK19 and Ret immunocytochemical staining for the MGCs of both SGT and PTC. The results of this study demonstrate that the cytological diagnosis of SGT can be improved by employing a combination of the typical and constant diagnostic cytological features and immunocytochemical results.","PeriodicalId":261069,"journal":{"name":"The Korean Journal of Cytopathology","volume":"78 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121792502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Manual Liquid-Based Cytology (Liqui-PREPtrade mark) in Breast Fine Needle Aspiration Cytology: Comparison with the Conventional Smears. 乳腺细针抽吸细胞学中的手工液体细胞学:与传统涂片的比较。

The Korean Journal of Cytopathology Pub Date : 2008-03-01 DOI: 10.3338/KJC.2008.19.1.34

J. Jeong, Jeong Shik Kim, Young Su Kim, H. Kim, Ji-Young Park

{"title":"Manual Liquid-Based Cytology (Liqui-PREPtrade mark) in Breast Fine Needle Aspiration Cytology: Comparison with the Conventional Smears.","authors":"J. Jeong, Jeong Shik Kim, Young Su Kim, H. Kim, Ji-Young Park","doi":"10.3338/KJC.2008.19.1.34","DOIUrl":"https://doi.org/10.3338/KJC.2008.19.1.34","url":null,"abstract":"Fine needle aspiration (FNA) cytology of the breast is a useful method for diagnosing breast lesions. Yet making the definite diagnosis with performing FNA is limited by some problems, such as the low cellularity, the poor preservation and the obscuring background. Recent studies have found that liquid-based cytology solves such problems, but it is an expensive method and it is limited by the loss of the background information. The purpose of this study is to compare the Liqui-, a new manual liquid-based method of cytology, and the conventional smears for analyzing breast FNA cytology materials. A total of 31 randomized FNA specimens of breast were studied. In each case, both the conventional smears and the Liqui- method were performed, and the smears were evaluated for cellularity, cellular preservation, the background, the cytologic features and the architectural arrangement. The cellularity and architectural arrangement were equal for both preparations. The Liqui- specimens showed better cellular preservation, loss of the obscuring background, no overlapping of cells and a smaller area to screen compared with the conventional smears. Moreover, it has the potential advantages of being able to use the remaining specimens for immunohistochemical study and ploidy analysis, and it can reduce the costs for preparation compared with the other liquid-based methods of cytology. But some background information is lost in the Liqui- specimens, the same as the other liquid-based methods of cytology. In conclusion, the Liqui- and conventional smears showed good correlation, but they have their respective advantages and disadvantages. These results suggest that Liqui- can contribute to making the accurate diagnosis with performing breast FNA cytology when it is used along with other methods.","PeriodicalId":261069,"journal":{"name":"The Korean Journal of Cytopathology","volume":"101 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124553062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Cytologic Findings of Fine Needle Aspiration Biopsy of 23 Schwannomas 23例神经鞘瘤细针穿刺活检的细胞学表现

The Korean Journal of Cytopathology Pub Date : 2008-03-01 DOI: 10.3338/KJC.2008.19.1.41

S. Chang, M. Joo, Han-Seong Kim

{"title":"Cytologic Findings of Fine Needle Aspiration Biopsy of 23 Schwannomas","authors":"S. Chang, M. Joo, Han-Seong Kim","doi":"10.3338/KJC.2008.19.1.41","DOIUrl":"https://doi.org/10.3338/KJC.2008.19.1.41","url":null,"abstract":"In an attempt to better define the cytologic characteristics of schwannomas, we have reviewed aspirates and corresponding histologic sections from 23 schwannomas. Of this number, the original cytologic diagnoses were: schwannoma in 14 cases (61%), benign soft tissue tumor in 2 cases (9%), and insufficient specimen in 7 cases (30%). The cytologic findings common to all cases of schwannoma included fragments of tightly cohesive fascicles with variable cellularity and corresponding Antoni type A area. The Antoni type B area, consisting of scattered spindle cells and some histiocytes and lymphocytes against a myxoid background, was seen in 14 cases. Fibrillary stroma was seen in 12 cases. The tumor cells had spindle- or ovalshaped nuclei, with pointed ends and indistinct cell borders. Nuclear palisading was seen in 10 cases, and distinctive Verocay bodies were seen in 5 cases. In ancient schwannomas, there were no Verocay bodies. Most schwannomas have distinct cytomorphologic features that allow correct diagnosis. The major problem with fine needle aspiration cytology of these tumors is the high frequency of poor cellularity, particularly in lesions with cystic degeneration. Of 7 cases with insufficient specimen, 4 showed marked cystic changes and 1 showed marked hyaline changes on histologic sections. In conclusion, we believe that if cytopathologist reminds the situation such as cystic degeneration or hyaline degeneration, the correct diagnosis of the schwannoma will be easily made.","PeriodicalId":261069,"journal":{"name":"The Korean Journal of Cytopathology","volume":"309 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134239443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Touch Imprint and Fine Needle Aspiration Cytology of Giant Cell Tumor of Tendon Sheath - A Case Report - 肌腱鞘巨细胞瘤的触摸压印及细针抽吸细胞学1例报告

The Korean Journal of Cytopathology Pub Date : 2008-03-01 DOI: 10.3338/KJC.2008.19.1.57

Jong Im Lee

{"title":"Touch Imprint and Fine Needle Aspiration Cytology of Giant Cell Tumor of Tendon Sheath - A Case Report -","authors":"Jong Im Lee","doi":"10.3338/KJC.2008.19.1.57","DOIUrl":"https://doi.org/10.3338/KJC.2008.19.1.57","url":null,"abstract":"Giant cell tumor of the tendon sheath (GCTTS) is a slowly growing, benign soft tissue tumor. The tumors occur predominantly on the hands and feet. Although the clinical and histopathologic features are well-defined, only a few reports have described the cytologic appearance of this entity. A 26-year-old woman presented with a gradually developing circumscribed soft tissue mass near the proximal phalanx of her left little finger for one year. Imprint and fine needle aspiration (FNA) smears were obtained from the excisional biopsy specimen. The imprint smears were composed of predominantly singly dispersed bland mononuclear cells and several giant cells. The mononuclear cells were polygonal to round, and they showed a histiocyte-like appearance. Osteoclast-type multinucleated giant cells of various sizes were randomly scattered throughout the smears, and these cells contained 3 to 50 nuclei. Nuclear atypia and pleomorphism were absent in both the single and giant cells. Loose aggregates of hemosiderin-laden macrophages and binuclear stromal cells were also seen. The cytologic features of the FNA smears were similar with those of the imprint, Additionally, the FNA smears contained several clumps of densely collagenous stromal tissue that were seldom noted in previously reported cytologic material. The cytologic features were well-correlated with the concurrent histologic findings and the diagnosis of GCTTS was made. When the clinical and radiologic datas are integrated, the diagnosis of GCTTS can be strongly suggested, based on the pre-operative cytologic specimen.","PeriodicalId":261069,"journal":{"name":"The Korean Journal of Cytopathology","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126896275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Cytologic Features of Epithelial-Myoepithelial Carcinoma Occurring in External Auditory Canal - A Case Report - 外耳道上皮-肌上皮癌的细胞学特征- 1例报告

The Korean Journal of Cytopathology Pub Date : 2008-03-01 DOI: 10.3338/KJC.2008.19.1.52

Ho-chang Lee, H. Song, Young-Seok Choi, O. Lee

引用次数: 0

Fine Needle Aspiration Cytologic Findings of Pulmonary Neuroendocrine Tumors 肺神经内分泌肿瘤的细针穿刺细胞学表现

The Korean Journal of Cytopathology Pub Date : 2008-03-01 DOI: 10.3338/KJC.2008.19.1.9

J. Koh

引用次数: 0

Cytological Diagnosis of Lung Cancer: The Diagnostic Accuracy and Pitfalls 肺癌的细胞学诊断:诊断的准确性和缺陷

The Korean Journal of Cytopathology Pub Date : 2008-03-01 DOI: 10.3338/KJC.2008.19.1.1

W. Kim

引用次数: 1

Cytologic Features of Cancers Metastatic to the Lung and Diagnostic Usefulness of Immunohistochemistry: Distinction Between Primary and Secondary Lung Tumors. 肺转移癌的细胞学特征和免疫组织化学的诊断价值:原发性和继发性肺肿瘤的区别。

The Korean Journal of Cytopathology Pub Date : 2008-03-01 DOI: 10.3338/KJC.2008.19.1.16

Y. Oh

引用次数: 0