{"title":"Potential Treatment of Autism with Traditional Chinese Medicine","authors":"D. Y. Lee, Xuejun Kong","doi":"10.7156/V5I3P189","DOIUrl":"https://doi.org/10.7156/V5I3P189","url":null,"abstract":"","PeriodicalId":260439,"journal":{"name":"American Chinese Journal of Medicine and Science","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126010141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The 2009 Swine-Origin H1N1 Influenza Virus and its Implications to Public Health","authors":"Sha Lu","doi":"10.7156/v3i1p034","DOIUrl":"https://doi.org/10.7156/v3i1p034","url":null,"abstract":"[N A J Med Sci. 2010;3(1): 034-035.] The major public health event in 2009 is the outbreak of a new influenza virus infection in almost every region of the world. Because the original source of this virus was pigs, this virus was named “Swine-Origin Influenza A (H1N1) Virus (S-OIV)” in leading medical journals such as the New England Journal of Medicine. However, due to concerns regarding the potential for a misunderstanding that would lead the public to blame pigs for the outbreak as was the case in some Mideast countries where the national slaughter of pigs was started shortly after the outbreak, the World Health Organization (WHO) renamed the virus as “Type A H1N1 Influenza Virus”, which has generated significant confusion not only among the general public but also among healthcare professionals.","PeriodicalId":260439,"journal":{"name":"American Chinese Journal of Medicine and Science","volume":"90 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128794203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Looking for Biomarkers for Prostate Cancer Early Detection","authors":"B. Lu, M. Sanda","doi":"10.7156/V2I3P081","DOIUrl":"https://doi.org/10.7156/V2I3P081","url":null,"abstract":"","PeriodicalId":260439,"journal":{"name":"American Chinese Journal of Medicine and Science","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125526311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Antipsychotics Medication Use and its Metabolic Challenges for Autism Spectrum Disorders","authors":"G. García","doi":"10.7156/V5I3P162","DOIUrl":"https://doi.org/10.7156/V5I3P162","url":null,"abstract":"There has been a growth in the knowledge about autism and autism spectrum disorders (ASD) in the United States and worldwide. As the prevalence rates have grown, so has the awareness of the need to develop effective and safe treatments for children with ASD. In addition to the behavioral interventions such as applied behavioral analysis, parent training, and adaptive skills training, there has been an increase in the use of medications for the treatment of ASD symptoms. At this time, there are two antipsychotics approved by the FDA for the use in children with ASD, risperidone and aripiprazol. Generally, the use of this classification has been more recently associated with changes in metabolic function in children. The purpose of this article is to review briefly the use of psychotropic medications, focusing on antipsychotics, and discuss the metabolic risks and risk factors associated with their use within children with autism. [N A J Med Sci. 2012;5(3): 162-166.]","PeriodicalId":260439,"journal":{"name":"American Chinese Journal of Medicine and Science","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130125388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Discovery of a Pseudo SNP and its Usage in Gender Test","authors":"Jie Huang","doi":"10.7156/v2i1p041","DOIUrl":"https://doi.org/10.7156/v2i1p041","url":null,"abstract":"Single Nucleotide Polymorphism (SNP) technology has been widely used in genome-wide association studies (GWAS). Quality control procedures usually includes testing minor allele frequency, hardy–weinberg equilibrium, call frequency, and concordance rate. However, little effort has been reported to validate a SNP itself. Here we report how a SNP is found not to be actual polymorphic at one locus, instead from two sequences on two different chromosomes. [N A J Med Sci. 2009;2(2):41.]","PeriodicalId":260439,"journal":{"name":"American Chinese Journal of Medicine and Science","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115259170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Susanna Syriac, W. Mojica, Frank Chen, Shaozeng Zhang
{"title":"Cystic Renal Oncocytoma: A Case Report with Review of the Literature","authors":"Susanna Syriac, W. Mojica, Frank Chen, Shaozeng Zhang","doi":"10.7156/V2I3P097","DOIUrl":"https://doi.org/10.7156/V2I3P097","url":null,"abstract":"oncocytomas are benign, predominantly asymptomatic tumors that are usually found incidentally. These tumors are typically solid, well-circumscribed, homogenous tan-brown lesions, often with a central fibrous scar. Histologically, the tumor cells are arranged in solid compact nests, acini and tubules of variable size, all within a hypocellular hyalinized stroma. In the literature, there are only five cases of cystic renal oncocytoma reported. Herein we present a case of cystic renal oncocytoma with the unusual gross appearance of multiloculation. It was found incidentally on imaging studies in the upper pole of the right kidney. Grossly, it was a well-circumscribed 1.5 cm mass with a multiloculated cystic cut surface. Microscopically, the oncocytic cells were arranged along the septae that divided the mass into multiloculated cysts. Immunohistochemical staining of the tumor showed expression of kidney-specific cadherin in all the neoplastic cells, CK7 expression in 45% and PAX-2 expression in 60% of these cells. RCC and vimentin showed no reactivity within the tumor. The morphological features and immunohistochemical studies confirmed the diagnosis of a cystic renal oncocytoma. (N A J Med Sci. 2009;2(3):97-98.) Case report A 46-year-old female presented with a few months history of postprandial abdominal pain in her right upper quadrant. An abdominal ultrasound revealed an echogenic round mass in the upper pole of her right kidney, with the initial radiological impression being that of an angiolipoma. A subsequent CT scan confirmed the presence of a 1.4 cm mass with findings suspicious for a renal cell carcinoma. The patient was thereafter advised to have the mass removed. Pathological findings Examination of the resected kidney revealed a well- circumscribed tan-brown multiloculated cystic mass in the upper pole, measuring 1.5 cm in greatest dimension. Microscopically, cuboidal to polygonal cells with abundant pink granular cytoplasm were arranged along septae that divided the mass into a multiloculated cyst. The nuclei were round with uniform nuclear contours and evenly dispersed chromatin. Many cells showed prominent nucleoli, with a few cells demonstrating binucleation. Atypia, mitotic activity and necrosis were all absent. No clear cells or reticulated cells were noted. These histopathological features were consistent with a renal oncocytoma.","PeriodicalId":260439,"journal":{"name":"American Chinese Journal of Medicine and Science","volume":"105 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124090273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Relationship between Primary Extrauterine Adenosarcoma and the Secondary Müllerian System: Report of a Unique Case Demonstrating Histologic Transition between Benign and Malignant Elements and a Review of the Literature","authors":"Wei Liu, C. Axiotis","doi":"10.7156/V3I3P132","DOIUrl":"https://doi.org/10.7156/V3I3P132","url":null,"abstract":"Background: Extrauterine adenosarcomata are thought to arise from pre-existing foci of endometriosis. In 1925 Sampson proposed three criteria for a definitive diagnosis of malignancy arising in endometriosis: (1) histological evidence of endometriosis in close proximity to the tumour; (2) no other identifiable primary site of malignancy; and (3) histological appearance of the tumour compatible with an origin in endometriosis. In 1953 Scott added a fourth criterion (4) requiring contiguous histological transition of benign endometriosis merging with the malignant component. Case Report: We report an unusual and unique case of extrauterine mullerian adenosarcoma which fulfills both Sampson’s and Scott’s criteria and review the literature on extrauterine adenosarcoma and their relationship with the extended mullerian system. We also demonstrate that lymph node “metastases” of adenosarcoma may arise from pre-existing endometriosis.","PeriodicalId":260439,"journal":{"name":"American Chinese Journal of Medicine and Science","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128184262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xixi Amley, Lou Mastrine, Jason Esses, G. Hollander
{"title":"Rivastigmine Adverse Effects: Complete Heart Block","authors":"Xixi Amley, Lou Mastrine, Jason Esses, G. Hollander","doi":"10.7156/V3I4P199","DOIUrl":"https://doi.org/10.7156/V3I4P199","url":null,"abstract":"Context: Rivastigmine (Exelon), a brain selective cholinesterase inhibitor, is used in the treatment of Alzheimer’s Disease (AD) to improve cognitive functions. Case Report: We report a case in which the addition of rivastigmine to memantine and metoprolol resulted in complete heart block and possibly predisposing a patient to syncope. Conclusion: Rivastigmine should be used with caution, especially in patients with such structural heart diseases as aortic stenosis and those taking other medications that may contribute to bradycardia. [N A J Med Sci. 2010;3(4):199-200.]","PeriodicalId":260439,"journal":{"name":"American Chinese Journal of Medicine and Science","volume":"47 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129674539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Parinaud Oculoglandular Syndrome as a Prominent Presenting Feature of Kikuchi-Fujimoto Disease - A Case Report and Review of the Literature","authors":"D. Hoehn, K. Bala, W. Fan, C. Yin","doi":"10.7156/V4I1P096","DOIUrl":"https://doi.org/10.7156/V4I1P096","url":null,"abstract":"Kikuchi-Fujimoto disease (KFD) is an often underdiagnosed form of lymphadenitis that clinically mimics lymphoma. Ocular manifestations are rare in patients with KFD and are under-appreciated in the literature. We describe a man who presented with eye redness, blurred vision, and pain on upward gaze associated with fever, weight loss and cervical lymphadenopathy. This presentation was initially interpreted as Parinaud oculoglandular syndrome which is most often caused by infection leading to an infectious workup. Lymph node biopsy was eventually performed and showed KFD. Kikuchi-Fujimoto disease needs to be added to the list of known causes of Parinaud oculoglandular syndrome. [N A J Med Sci. 2011;4(2):96-99.]","PeriodicalId":260439,"journal":{"name":"American Chinese Journal of Medicine and Science","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124390530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Update on HBV Treatment and Management of Antiviral Resistance","authors":"D. Lau","doi":"10.7156/V4I1P035","DOIUrl":"https://doi.org/10.7156/V4I1P035","url":null,"abstract":"Chronic hepatitis B (CHB) is a major public health problem affecting up to 400 million people globally. Complications of CHB including liver failure and hepatocellular carcinoma result in 1.2 million deaths per year, making CHB the 10 th leading cause of mortality worldwide. The natural history of CHB is variable and complex. The past decade witnessed important developments for the therapy of hepatitis B and marked the new era of oral therapy. The ultimate goal of CHB therapy is to arrest the progression of liver injury and to prevent the development of liver failure and hepatocellular carcinoma. Currently, six agents are approved for the treatment of CHB. Each of these agents, given as monotherapy, has been shown to produce virological, biochemical and histological benefits for both HBeAg positive and negative CHB. There are, however, limitations in spite of their efficacy. The significant sideeffect profile of interferon, for example, limits its longterm use. The approved oral agents are tolerable with prolonged use but drug resistance could limit long-term monotherapy. To date, combination therapy with nucleoside analogue and pegylated interferon or two nucleos(t)ide analogues given for one year does not show superiority in durability of response compared to monotherapy. Ongoing research effort is critical to identify the ideal hepatitis B therapy that is safe, effective and produces durable response with a finite course of therapy. It is equally important to conduct a well designed, prospective natural history study to identify predictors of disease progression. This will accurately guide treatment strategy for this important disease. [N A J Med Sci. 2011;4(1):35-43.]","PeriodicalId":260439,"journal":{"name":"American Chinese Journal of Medicine and Science","volume":"60 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127726641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}