HERALD OF SCIENCE OF S SEIFULLIN KAZAKH AGRO TECHNICAL RESEARCH UNIVERSITY : Veterinary sciences最新文献

{"title":"OBTAINING OXYTETRACYCLINE CONJUGATES WITH PROTEIN CARRIERS","authors":"A. N. Jangulova, B. S. Temirgaziyev, A. Bulashev, Zhanara Zh Akanova, Shynar S Serikova","doi":"10.51452/kazatuvc.2023.1(001).1335","DOIUrl":"https://doi.org/10.51452/kazatuvc.2023.1(001).1335","url":null,"abstract":"Oxytetracycline is widely used in veterinary medicine for the treatment of animals, as well as growth promoters. They can have adverse effects on human health through animal products if the rules for the use of antibiotics are not followed. The World Health Organization has established maximum residue limits of antibiotics in milk and meat, which require accurate, rapid and inexpensive methods to determine. Immunochromatographic assay (ICA) is ideal for this purpose due to its speed of analysis, high sensitivity and ease of use. This paper describes the results of study on the obtaining an oxytetracycline (OTC) conjugate with bovine serum albumin (BSA) and/or ovalbumin (OVA). OTC has been chemically purified from the antibiotic hydrochloride salt (OTC HC), which is widely used in animal husbandry and is more affordable than its chemically pure analogue. Spectrophotometric analysis of the prepared conjugates and immunization of laboratory animals showed the suitability of OTC, chemically purified from OTC HC, for crosslinking into BSA and/or OVA molecules and obtaining hapten-specific antibodies. The results obtained could be used for the manufacture of ICA components - labeled OTC-specific antibodies and test line antigen.","PeriodicalId":251258,"journal":{"name":"HERALD OF SCIENCE OF S SEIFULLIN KAZAKH AGRO TECHNICAL RESEARCH UNIVERSITY : Veterinary sciences","volume":"91 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133694288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"SEARCH FOR THE THERAPEUTIC POTENTIAL OF BIOLOGICALLY ACTIVE SUBSTANCES CONTAINED IN CONIFEROUS PLANTS","authors":"Aidarkhanova Gulnar, Kukhar Elena, Vladimirovna","doi":"10.51452/kazatuvc.2023.1(001).1349","DOIUrl":"https://doi.org/10.51452/kazatuvc.2023.1(001).1349","url":null,"abstract":"The paper presents scientific information about the problems in the search for therapeutic potential in coniferous plants widely used in folk medicine. Samples of  coniferous plants growing in the mountain forests of the Western Altai in the eastern part of Kazakhstan were selected for the experiment: Baltic pine (Pinus sylvestris L.), European spruce (Picea abies L.), Siberian fir (Abies sibírica), Siberian pine (Pinus sibirica DuTour), and common juniper (Juniperus communis L.). During the study, the phytochemical composition of the components of P. sylvestris L. essential oils was determined by the indicators of sesquiterpenic fraction (69.76%), terpenoids (20.0%), and monoterpenes (5.51%). Using modern methods of studying biological activity (antimicrobial, antifungal, and anthelmintic), the authors established the presence of biological activity in the extracts of selected coniferous plants. In all coniferous plants, bactericidal activity was manifested in water decoctions, where biological preparations of Siberian fir and Baltic pine were more active. The oil extracts showed less bactericidal activity. Among them, extracts of Siberian pine and juniper were inactive, and the extract of European spruce was more active in its native form and 1:2 dilution. Among plants with a complete absence of bactericidal activity against the Candida parapsilosis opportunistic yeast, Siberian fir should be named. In other coniferous plants (European spruce, Baltic pine, juniper), bactericidal activity was detected only in oil solutions in a dilution of 1:2, and oil extract of Siberian pine in a dilution of 1:8 had a suppressive effect. Water/alcohol tincture of Siberian fir was found to have high fungicidal activity against Aspergillusniger, which continued to influence the growth of the micromycete at a dilution of 1:64 during the observation period. The presence of antiparasitic properties was observed in some plant extracts of coniferous forest plants. The best results were noted in alcohol tinctures of Baltic pine, juniper, and Siberian pine.","PeriodicalId":251258,"journal":{"name":"HERALD OF SCIENCE OF S SEIFULLIN KAZAKH AGRO TECHNICAL RESEARCH UNIVERSITY : Veterinary sciences","volume":"95 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122666687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"STUDIES OF FISH AND FISH PRODUCTS FOR THE PRESENCE OF HEAVY METAL SALT AND RADIONUCLIDES IN WATER BODIES OF THE WEST KAZAKHSTAN REGION","authors":"Nurgaliуev Birzhan Elubaevich, Zhumabaуev Askhat Konysbaevich, Kushmukhanov Zhenis, Kadralieva Bakytkanym Talapovna, Ussenov Zhangeldi Tarikhovich, Inirbayev Asylkhan Kabiyevich","doi":"10.51452/kazatuvc.2023.1(001).1348","DOIUrl":"https://doi.org/10.51452/kazatuvc.2023.1(001).1348","url":null,"abstract":"With the increase in production and processing industries, as well as the extraction of minerals in the territory of the Republic of Kazakhstan, it leads to pollution of the environment, ecology, wildlife and water resources of our country. All production capacities in agriculture and animal husbandry require water resources. As part of the research work, diagnostics were carried out on the content of salts of heavy metals and radioactive substances in the water bodies of the West Kazakhstan region, where they originate with transboundary rivers and an oil and gas field (KPO) is being produced. To carry out our research work, samples of fish products were taken from 15 reservoirs and 3 objects of domestic trade for laboratory testing for the content of salts of heavy metals (Pb, Cd) and radionuclides (Sr-90, Cs 134). Radioactive substances accumulate in the bones and muscles of fish, and subsequently enter the human body through ingestion. The risk of developing adverse effects on human health depends on the radiation dose. If the radiation dose is low, or if exposure occurs over a long period of time, the risk is much lower as the human body repairs damaged cells and molecules. Lead and cadmium harm the human nervous system and its mental development, it can cause kidney damage and lead to bone disease. It is necessary to constantly monitor the content of salts of heavy metals and radionuclides in fish and livestock products, since safe products are a guarantee of public health.","PeriodicalId":251258,"journal":{"name":"HERALD OF SCIENCE OF S SEIFULLIN KAZAKH AGRO TECHNICAL RESEARCH UNIVERSITY : Veterinary sciences","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125226906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"VETERINARY SANITARY EXAMINATION AND HELMINTOSIS COMPARATIVE MONITORING OF FISH OF WATER SOURCES OF KORGALZYN DISTRICT, AKMOLA REGION","authors":"Tleulesov Rahimtai, Boranbekovich, Inirbayev Asylkhan Kabievich, Bakishev Temirlan Gomarovich, Baikonys Temirlan Baikonysuly, Issa Ulan Serikuly","doi":"10.51452/kazatuvc.2023.1(001).1321","DOIUrl":"https://doi.org/10.51452/kazatuvc.2023.1(001).1321","url":null,"abstract":"This article presents the results of studies on helminthological diseases of carp species living in the rivers Nura, Tengiz, Birtaban, Shalkar, Uyaly, Sholak, Alkasor of the Korgalzhyn region. 226 studied fish samples were subjected to comparative monitoring using helminthological methods. When examining the fish of the reservoirs of the Korgalzhyn district of the Akmola region, 41.1% of the fish were found unfit for organoleptic indicators. As a result of laboratory studies, fish samples taken from the Sholak, Alkasor and Uyaly rivers were recognized as unsuitable, while the indicators of the studied fish from the Nura river and lakes Shalkar, Tengiz, Birtaban were within the normal range. According to the study, 6.4% of diplostomiasis in Lake Shalkar and 28.6% of opisthorchiasis in Lake Alkasor are affected by helminthiases. 16.6% postdiplostomiasis in the lakes Shalkar and Birtaban, 10.5% opisthorchiasis in the Nura River. In Lake Sholak, ligulase was 9.1% .","PeriodicalId":251258,"journal":{"name":"HERALD OF SCIENCE OF S SEIFULLIN KAZAKH AGRO TECHNICAL RESEARCH UNIVERSITY : Veterinary sciences","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125376328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}