International Blood Research & Reviews最新文献

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Maternal Hemoglobin Levels as a Causative Factor in Incidence of Low Birth Weight Babies: A Public Health Prospective 孕产妇血红蛋白水平是出生体重不足婴儿发病率的诱因:一项公共卫生前瞻性研究
International Blood Research & Reviews Pub Date : 2023-12-29 DOI: 10.9734/ibrr/2023/v14i4328
Ekarini Daroedono, Aurelia Evina Haloho, Restu Fatimatuzzahra
{"title":"Maternal Hemoglobin Levels as a Causative Factor in Incidence of Low Birth Weight Babies: A Public Health Prospective","authors":"Ekarini Daroedono, Aurelia Evina Haloho, Restu Fatimatuzzahra","doi":"10.9734/ibrr/2023/v14i4328","DOIUrl":"https://doi.org/10.9734/ibrr/2023/v14i4328","url":null,"abstract":"Aims: To analyze some aspects of the maternal and the newborn in the incidence of low birth weight babies (LBWB). Study Design: simple retrospective with cross-sectional design approach. Place and Duration of Study: Retrospective data of LBWB obtained from newborn medical record (year 2017-2022) of The Sultan Thaha Saifuddin Tebo Regional Public Hospital, located in Jambi-Indonesia and analysis conducted in the Departemen Kedokteran Komunitas (Community Medicine), the Faculty of Medicine, Universitas Kristen Indonesia, Jakarta Indonesia, between September-November 2023. Methodology: The inclusion criteria focus on all newborn with LBWB that have complete medical record data. The acquired data regarding (1) maternal age, gestational age at the time of giving birth, Hb level prior to delivery, (2) newborn: gender, survivability and birth weight. All respondents will be subjected to statistical analysis using the SPSS programme and Microsoft Excel 2016. The exhibited information consists of data distribution presented in the form of tables and utilising univariate analysis and regression testing. Results: Analysis of 256 LBWB data (122 (47.65%) boys, 134 (52.34%) girls) revealed that in the maternal side mean age 28.54 years old, mean gestational age 36.07 weeks at the time of giving birth and mean Hb level 10.8 gram/dL. In the newborn side viability were 226 (88.33%) viable and mean overall birth weight 1990.2 g. Statistically using Pearson correlation, there is a very weak correlation firstly among maternal Hb count with the neonates primary weight (P = 0.00, r = 0.154) and secondly between gestational age and the birth weight of newborn (P = 0.00, r = 0.000). From the community medicine perspective, Efforts to increase the Hb levels of pregnant women theoretically can be carried out more easily by encouraging and increasing the mother's and also their partners, families and society awareness of carrying out routine antenatal care, encouraging the role of health motivator/local health cadre and conducting Hb examination as simple screening; all of them supported by the government. Conclusion: Maternal low Hb count and gestational age correlate with birth weight of newborn. Further in depth and extensive study needed to explore specific factors contribute to the incidence of anemia in mother who gave birth neonates which have low birth weight (LBW) and their impact to pregnancy.","PeriodicalId":249518,"journal":{"name":"International Blood Research & Reviews","volume":" 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139144765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Secondary Erythrocytosis, a Predominant Cause of Polycythemia- Clinical and Laboratory Evaluation of Polycythemia in a Tertiary Care Center 继发性红细胞增多症是多血症的主要病因--一家三级医疗中心对多血症的临床和实验室评估
International Blood Research & Reviews Pub Date : 2023-12-18 DOI: 10.9734/ibrr/2023/v14i4327
Zunaira Aamir, M. Mushtaq, Sumera Sheikh
{"title":"Secondary Erythrocytosis, a Predominant Cause of Polycythemia- Clinical and Laboratory Evaluation of Polycythemia in a Tertiary Care Center","authors":"Zunaira Aamir, M. Mushtaq, Sumera Sheikh","doi":"10.9734/ibrr/2023/v14i4327","DOIUrl":"https://doi.org/10.9734/ibrr/2023/v14i4327","url":null,"abstract":"Aims: Polycythemia refers to an increased production of red blood cells from bone marrow. It is one of the frequent reasons for a hematology consultation. The present work aimed to examine the causes, clinical manifestations, prevalence, and diverse patterns in laboratory and clinical parameters among patients with polycythemia attending our outpatient clinics at the Indus Hospital and Health Network. Study Design: The present work is retrospective observational study which included all cases of polycythemia. Place and Duration of the Study: The study was conducted at a tertiary health care center in Karachi, Pakistan during October 2019 to July 2021. Methodology: The data from the patient diagnosed with polycythemia was entered and analyzed by using SPSS version 24.0. Descriptive statistics as per the Gaussian Normality distribution (Sapiro-Wilk) were computed along with frequencies. The association where applicable was calculated via standard statistical methods with the chi square test for categorical while independent sample t-test for the continuous variables. The level of statistical significance will be set at P < 0.05. Results: During the investigated period, a total of 33 patients were diagnosed with polycythemia demonstrating a notable male predominance (82%). The majority of the patients exhibited secondary erythrocytosis (85%) with only a minority (15%) diagnosed with polycythemia vera. Of the identified cases of secondary erythrocytosis a significant proportion (46%) was observed in individuals who were smokers while other were found with hypoxic pulmonary disease, hepatitis, and chronic kidney disease. In secondary erythrocytosis 21 patients (75%) required venesection for symptom reduction, while 7 (25%) were closely monitored due to their asymptomatic status. On the contrary all cases of polycythemia vera required a comprehensive treatment approach including venesections, cytoreduction with hydroxyurea and low dose aspirin.","PeriodicalId":249518,"journal":{"name":"International Blood Research &amp; Reviews","volume":"69 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139173849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Organizing Community Participation in Humanitarian Blood Donation Activities 组织社区参与人道主义献血活动
International Blood Research &amp; Reviews Pub Date : 2023-12-05 DOI: 10.9734/ibrr/2023/v14i4326
Yusias Hikmat Diani, L. S. Sunarti, Trini Suryowati, Romauli Lumbantobing, Morado Natanael Sidauruk, Jeremya Yogi Putra, Hidekel Tambunan, Daniel Jhosias Samosir
{"title":"Organizing Community Participation in Humanitarian Blood Donation Activities","authors":"Yusias Hikmat Diani, L. S. Sunarti, Trini Suryowati, Romauli Lumbantobing, Morado Natanael Sidauruk, Jeremya Yogi Putra, Hidekel Tambunan, Daniel Jhosias Samosir","doi":"10.9734/ibrr/2023/v14i4326","DOIUrl":"https://doi.org/10.9734/ibrr/2023/v14i4326","url":null,"abstract":"Aim: To organize and to encourage community participation in humanitarian blood donation held by the Indonesian Red Cross in collaboration with local church. Discussion: The culture of voluntary blood donation must always be encourage, in order to guarantee timely access to safe blood and blood products and help save lives. Compliment and appreciation given to noble donation of voluntary donors who receive no remuneration but are always ready and available to donate blood to help save other lives most of whom they never meet. Using popular social media, action taken to promote, mobilize, and publish educational materials on voluntary blood donation campaigns as well as encourage local potential donor to donate voluntarily. This activity is also the implementation of the noble human values ​​of sharing, giving and caring Conclusion: Connecting all stakeholders helps to make the blood donation succesfull.","PeriodicalId":249518,"journal":{"name":"International Blood Research &amp; Reviews","volume":"112 15","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138599474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hematological Profile of Adult Haemoglobin SS and SC Sickle Cell Patients in Stationary Phase: Evidences from National Teaching Hospital of Cotonou in Benin 固定期成人血红蛋白SS和SC镰状细胞患者血液学特征:来自贝宁科托努国立教学医院的证据
International Blood Research &amp; Reviews Pub Date : 2023-08-28 DOI: 10.9734/ibrr/2023/v14i4319
A. Zohoun, T. Baglo-Agbodande, B. Houssou, R. Massi, E. Kassehin, G. G. O. Guiwa, J. Dèhoumon, J. Mehou, L. Anani, A. Vovor, D. Kindé-Gazard
{"title":"Hematological Profile of Adult Haemoglobin SS and SC Sickle Cell Patients in Stationary Phase: Evidences from National Teaching Hospital of Cotonou in Benin","authors":"A. Zohoun, T. Baglo-Agbodande, B. Houssou, R. Massi, E. Kassehin, G. G. O. Guiwa, J. Dèhoumon, J. Mehou, L. Anani, A. Vovor, D. Kindé-Gazard","doi":"10.9734/ibrr/2023/v14i4319","DOIUrl":"https://doi.org/10.9734/ibrr/2023/v14i4319","url":null,"abstract":"Background and Objective: Sickle cell disease is a major public health problem. The aim of this study was to determine the hematological parameters in the inter-critical period of adult sickle cell patients at the National Teaching Hospital CNHU-HKM of Cotonou. \u0000Materials and Methods: This is a descriptive study with analytical aims carried out from July 2021 to December 2021 in the hematology department of the National Teaching Hospital CNHU-HKM of Cotonou. An hemogram was performed using Sysmex XT 4000i on a total of 181 sickle cell patients including 119 Hb SS and 62 Hb SC. Data were analyzed using R software. \u0000Results: Patients studied had a mean age of 32 ± 13 years. The mean of hemoglobin level was 7.7 ± 1.9 g/dL in Hb SS patients versus 11.27 ± 1.79 g/dL in Hb SC patients (p = 0.001). The mean leukocyte count was 13.2 ± 4.4 G/L in Hb SS patients versus 7.3 ± 3 G/L in Hb SC patients (p = 0.003); the mean neutrophil count was 6.93 ± 3.24 G/L in Hb SS patients versus 3.96 ± 1.72 G/L in Hb SC patients (p = 0.001). Platelet counts averaged 426 ± 213 G/L in Hb SS patients versus 223 ± 103 G/L in Hb SC patients (p = 0.001). \u0000Conclusion: This study revealed a higher mean hemoglobin level, mean leukocyte count and mean platelet count in Hb SS patients compared to Hb SC patients in the stationary phase.","PeriodicalId":249518,"journal":{"name":"International Blood Research &amp; Reviews","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121288219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence of Hepatitis D Virus among Hepatitis B Positive Blood Donors in Port Harcourt, Nigeria 尼日利亚哈科特港乙型肝炎阳性献血者中丁型肝炎病毒的流行情况
International Blood Research &amp; Reviews Pub Date : 2023-08-24 DOI: 10.9734/ibrr/2023/v14i4317
Nwika Goodnews Nkabari, Jeremiah Zaccheaus Awortu, Eze, Evelyn Mgbeoma
{"title":"Prevalence of Hepatitis D Virus among Hepatitis B Positive Blood Donors in Port Harcourt, Nigeria","authors":"Nwika Goodnews Nkabari, Jeremiah Zaccheaus Awortu, Eze, Evelyn Mgbeoma","doi":"10.9734/ibrr/2023/v14i4317","DOIUrl":"https://doi.org/10.9734/ibrr/2023/v14i4317","url":null,"abstract":"Introduction: The Prevalence of Hepatitis D Virus among Blood Donors   in Port Harcourt, Nigeria is a maiden epidemiological study of   Hepatitis D or delta hepatitis among the donors’ population in Port Harcourt, Rivers State. Hepatitis D (Hepatitis Delta) is a disease caused by the hepatitis D virus (HDV). It is considered to be a sub viral satellite because it can propagate only in the presence of the hepatitis B virus. The prevalence of HDV in Port Harcourt has not been reported; hence this study, bridge that knowledge gap. \u0000Methods: Using a qualitative cross sectional study design, a general serological screening test was performed on a total of 300 blood donors recruited; 222(74.00%) males and 78 (26.00%) females, all within 20-59years. Of this number, 86(28.70%) were positive for HBV while 214(71.30%) Hepatitis B negative served as control. Samples collected were analysed at blood bank unit of the Haematology Department of the Rivers State University Teaching Hospital, Port Harcourt (RSUTH). Hepatitis B surface antigen (HBsAg), and anti-hepatitis D antibodies (anti-HDV) for the presence of HBV and HDV infections were detected by one step Hepatitis B surface antigen (HBsAg) in serum, and enzyme linked immunosorbent assay for the detection of HDV as described by the www.elabScience.com (16). \u0000Results: Of the 300 subjects, 86(28.6%) were positive for Hepatitis B surface antigen (HBsAg). Of these HBV positive subject, 9(10.4%) were positive for Hepatitis D virus (HDV). Age and gender of the study participants were not found to be risk factors for its prevalence (p > 0.05). There was no statistically significant difference in the PCV of those infected when compared with the non infected group. Using Pearson correlation analysis, HDV was not found to associate significantly with PCV (r = 0.2849, p > 0.05). This study recorded HDV prevalence rate of 10.4% among the HBsAg positive blood donors. \u0000Conclusion and Implications for Translation: There is a 10.4% prevalence of HDV among the HBsAg positive blood donors. To increase the safety level of blood products, the screening process should therefore be extended to the HDV. ","PeriodicalId":249518,"journal":{"name":"International Blood Research &amp; Reviews","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133615904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Platelet Storage: Time to Rethink the Cold 血小板储存:是时候重新考虑低温了
International Blood Research &amp; Reviews Pub Date : 2023-08-24 DOI: 10.9734/ibrr/2023/v14i4318
Cherise Farrugia, Byron Baron, V. Zammit
{"title":"Platelet Storage: Time to Rethink the Cold","authors":"Cherise Farrugia, Byron Baron, V. Zammit","doi":"10.9734/ibrr/2023/v14i4318","DOIUrl":"https://doi.org/10.9734/ibrr/2023/v14i4318","url":null,"abstract":"Platelet concentrates (PCs) are widely used in transfusion medicine for therapeutic purposes and their demand is constantly on the rise. Current storage regulations make this product highly susceptible to bacterial contaminations and platelet storage lesions (PSL) causing the need for alternative storage methods to be considered. The implementation of cold storage not only reduces unnecessary wastage of valuable donations and overall costs but also decreases both the risk of bacterial contamination and the occurrence of PSL. The current study aimed at determining how a prolonged cold storage may affect PCs. This was accomplished by investigating two different PC cohorts of 10 units each. One of the cohorts, labelled as ‘Room Temperature’, was stored at 22℃±2℃ for 5 days and then transferred to a temperature of 4℃±2℃. The other cohort, labelled as ‘Cold’, was stored directly at 4℃±2℃. Both cohorts were stored for a total of 21 days and platelet indices, platelet counts, pH, and platelet factor IV (PF4) were measured at different time intervals. Sterility was performed on Day 21. The key findings showed no significant difference in mean platelet count, platelet distribution width (PDW), mean platelet volume (MPV), platelet-large cell ratio (P-LCR), and plateletcrit (PCT) between the two cohorts. On the other hand, a significant difference in mean pH and PF4 resulted between the two cohorts. Moreover, no significant difference in mean platelet count, and PCT was found between Days 1, 5, or 10, and Day 21 in both cohorts. However, an overall significant difference in mean PDW, MPV, P-LCR and pH was discovered between Days 1 and 21, Days 5 and 21, and Days 10 and 21 in both cohorts. Regards PF4, a significant difference was detected between Days 1 and 21, and Days 10 and 21; however, no significant difference was found between Days 5 and 21 in both cohorts. Corynebacterium freneyi and Microbacterium liquefaciens, were cultured from 1 unit of the room temperature cohort after it was flagged positive during the sterility testing. In conclusion, through the implementation of a delayed cold storage system, PCs can be safely administered to the patient.","PeriodicalId":249518,"journal":{"name":"International Blood Research &amp; Reviews","volume":"92 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129385817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Statistical Analysis of Monocyte Monolayer Assay Validation in Brazilian Blood Donors 巴西献血者单核细胞单层检测验证统计分析
International Blood Research &amp; Reviews Pub Date : 2023-07-22 DOI: 10.9734/ibrr/2023/v14i4316
Jéssica Hanser Nunes Kahl, Everaldo José Schorner, E. Kupek
{"title":"Statistical Analysis of Monocyte Monolayer Assay Validation in Brazilian Blood Donors","authors":"Jéssica Hanser Nunes Kahl, Everaldo José Schorner, E. Kupek","doi":"10.9734/ibrr/2023/v14i4316","DOIUrl":"https://doi.org/10.9734/ibrr/2023/v14i4316","url":null,"abstract":"Aims: To validate the monocyte monolayer assay (MMA) technique concerning its suitability for blood donor screening and its cost per test performed. The MMA is an in vitro simulation of the behavior of the antibodies, demonstrating the reactions that would occur in the endothelial reticulum system after a transfusion of incompatible red blood cells, indicating the risk of a hemolytic transfusion reaction and therefore of the clinical significance of the antibodies. \u0000Study Design: Blood samples of alloimmunized patients, selected at random from a blood donation bank, were submitted to validation tests recommended by the Brazilian National Health Surveillance Agency for the approval of new testing procedures. \u0000Place and Duration of Study: The following Brazilian institutions were involved between June 2009 and July 2010: Immunohematology laboratory of the Hematology and Hemotherapy Center of Santa Catarina state in Florianópolis, Department of Medicine (Medical Unit IV) and Department of Radiology of the Institute of Medical Sciences, Hospital Lahore in São Paulo. \u0000Methodology: Ninety samples of alloimmunized patients treated by the Santa Catarina blood donors were used. The validation tests evaluated the selectivity, linearity, precision, and accuracy of the MMA method and determined the limits of detection and quantification. External validation of the method was performed by comparing these results with those of an independent laboratory in São Paulo, while making sure that the latter was blind to the results of the former. The coefficient of variation was used to express the MMA testing precision of 5 replicates across 5 different concentration levels. Type I error for evaluating statistical significance was set at 5%. \u0000Results: Selectivity assessment of the impact of multiple alloantibodies on the MMA test result showed no statistically significant difference (P>0.05) across the titers of 64, 256, and 2048, each with three replications, thus confirming the test specificity. Homoscedasticity of the monocyte index (MI) data was not refuted by Levine's test with the F-value of 0.746, much below the value of 3.056 needed to achieve a statistical significance level of P<0.05. MI linearity against the logarithm of the alloantibody concentration was shown in a simple linear regression where the latter predicted 83% of the variation in the former, and the regression slope of 0.4 (95% confidence interval 0.32, 0.48). The limits of detection and quantification on the logarithm scale were 0.28 and 0.84, respectively. External validation found no statistically significant difference between the MMA test results from the two independent laboratories. The coefficient of variation of <15% indicated good MMA testing precision under routine laboratory conditions. \u0000Conclusion: The assay met all validation criteria and was therefore effective in assessing the clinical significance of alloantibodies.","PeriodicalId":249518,"journal":{"name":"International Blood Research &amp; Reviews","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130487866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Penetrating Stab Wounds of the Spine: Two Cases and Review of the Literature 脊柱刺穿伤:两例及文献复习
International Blood Research &amp; Reviews Pub Date : 2023-07-15 DOI: 10.9734/ibrr/2023/v14i4315
Fondop Joseph, Atemkem Tsatedem Faustin, Banga Nkono Douglas, F. D. Dikongue, Amougou Boris, A. Djam, Dogmo Arlette, Djientcheu Vincent de Paul, Fuentes Stéphane
{"title":"Penetrating Stab Wounds of the Spine: Two Cases and Review of the Literature","authors":"Fondop Joseph, Atemkem Tsatedem Faustin, Banga Nkono Douglas, F. D. Dikongue, Amougou Boris, A. Djam, Dogmo Arlette, Djientcheu Vincent de Paul, Fuentes Stéphane","doi":"10.9734/ibrr/2023/v14i4315","DOIUrl":"https://doi.org/10.9734/ibrr/2023/v14i4315","url":null,"abstract":"Penetrating wounds of the spine caused by edged weapons are on the increase due to the growing insecurity, violence, availability and accessibility of these weapons, which are generally objects of everyday use (knife, axe, machete, screwdriver, bicycle spoke, scissors, garden fork, sickle and sharpened broom handle, etc.). These objects may be the cause of penetrating wounds responsible for neurological deficits with breaches of the dura mater, or they may be without neurological deficits due to the level of the weapon in the spine. We present two clinical cases of patients with penetrating knife wounds of the spine. One at cervical level with pneumorrhagic emphysema, spinal cord compression and pneunemoencephaly, with neurological deficit who had a surgical intervention followed by physiotherapy and a progressive recovery, the other with a penetrating wound at L5 crossing the blade to the vertebral body without neurological deficit in whom the knife was extracted at the emergency department without secondary deficit. \u0000Penetrating wounds of the spine are caused by stab wounds, including knives. In particular, emphysema, diffuse pneumorrhagia and pneumoencephalus are extremely rare in the same patient, this being due to the knife extraction technique. These lesions, associated with neurological deficit and cerebrospinal fluid (CSF) leakage, constitute a neurosurgical emergency.   ","PeriodicalId":249518,"journal":{"name":"International Blood Research &amp; Reviews","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115708296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of Some Haematological Metrics among Smokers in Port Harcourt, Rivers State, Nigeria 尼日利亚河流州哈科特港吸烟者的一些血液学指标评价
International Blood Research &amp; Reviews Pub Date : 2023-06-23 DOI: 10.9734/ibrr/2023/v14i4314
W. M. Beatrice, N. Goodnews, C. Priya, Lenox-Prince, Tamunonengiye-ofori
{"title":"Evaluation of Some Haematological Metrics among Smokers in Port Harcourt, Rivers State, Nigeria","authors":"W. M. Beatrice, N. Goodnews, C. Priya, Lenox-Prince, Tamunonengiye-ofori","doi":"10.9734/ibrr/2023/v14i4314","DOIUrl":"https://doi.org/10.9734/ibrr/2023/v14i4314","url":null,"abstract":"Introduction: Smoking is extremely toxic and has had a significant negative impact on society. One of the leading contributors to preventable illness and mortality has been found to be cigarette smoking. \u0000Aim: The goal of this study is to evaluate a few haematological metrics among smokers in Port Harcourt, Rivers State, and to verify the idea that smoking cigarettes either has a negative or favorable impact on these variables. \u0000Methodology: In this cross-sectional study, 100 participants between the ages of 20 and 45 were included, 50 of whom were smokers and 50 non-smokers. Venipuncture was used to obtain blood samples from the patients, which was then put into an EDTA vial for a full blood count (FBC) and other haematological analysis. The full blood count and erythrocyte sedimentation rate (ESR) were done using Haemo Auto Analyzer, Model XP-300 KOBE Japan by SYSMEX and the Westergreen method respectively.  In order to analyze the data, Graph Prism Pad 6.2 and Microsoft Office Excel 2016 were both used. Using the student's independent t-test, a comparative study of mean and standard deviation values for the various parameters for test and reference ranges was conducted. \u0000Results: According to the findings, the average age of 50 smokers was 43.6200± 9.7250 years and that for the 50 non-smokers was 42.7800± 6.5440 years, which was statistically insignificant with p valve of 0.6130. Smokers’ haemoglobin level was 14.5080 ± 1.5590 (g/dL) and non-smokers was 12.1340 ± 0.70410 (g/dL). According to statistics, the level of Hb was significantly higher in smokers compared to non-smokers (P<0.0001). In comparison to non-smokers, the RBC count dramatically increased in smokers (P<0.0001) greater than in non-smokers at 5.2550 ± 0.6629 (x1012/L) and 4.6340 ± 0.5530 (x1012/L) respectively. While the total leucocyte count (TLC) in smokers is 8.0500 ± 1.8796 (x109/L), compared to 6.8580 ± 1.2454 (x109/L) in non-smokers. Statistics show that smokers have a higher total leucocyte count than non-smokers (P<0.0002). Smokers' platelet count is 255.7600±61.8351 (x109/L) while non-smokers' is 216.5800±35.5752 (x109/L).The study has statistically shown that smokers' platelet counts rose considerably in comparison to non-smokers (P<0.012). \u0000Conclusion: It may be concluded that uninterrupted smoking has an undue negative impact on haematological parameters such that increase occur in values of Hb, RBC, TLC and platelets. Significantly, these changes may increase the risk of serious health issues such as heart related defects, hardening of the arteries, Vaquez-Osler disease. It is recommended that smokers have these metrics regularly monitored.","PeriodicalId":249518,"journal":{"name":"International Blood Research &amp; Reviews","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129530559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Gift of Blood: Opinions and Experience of Voluntary Blood Donors on Repeat Blood Donation 一份血液的礼物:无偿献血者对重复献血的意见与体会
International Blood Research &amp; Reviews Pub Date : 2023-06-05 DOI: 10.9734/ibrr/2023/v14i4313
Seif S. Khalfan, D. Kakoko
{"title":"A Gift of Blood: Opinions and Experience of Voluntary Blood Donors on Repeat Blood Donation","authors":"Seif S. Khalfan, D. Kakoko","doi":"10.9734/ibrr/2023/v14i4313","DOIUrl":"https://doi.org/10.9734/ibrr/2023/v14i4313","url":null,"abstract":"Donating blood is an essential practice that can help save lives. Effective strategies are necessary to attract and keep blood donors to meet the demand for safe blood. To evaluate the experience of voluntary blood donors in Zanzibar, a survey was conducted, and purposive sampling was used to select participants who had donated blood multiple times. The study involved interviewing 15 repeat blood donors, and the data collected was analyzed thematically. Two main themes emerged from the analysis: motivators and barriers. Despite a few negative effects, most participants had positive experiences with repeat blood donation, and only few experienced physical reactions during or after the process. The study concludes that blood donors in Zanzibar generally have good experience towards repeat blood donation, although community participation, education, and sensitization are needed to recruit and maintain more donors.","PeriodicalId":249518,"journal":{"name":"International Blood Research &amp; Reviews","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122723322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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