Austin Journal of Dermatology最新文献

Congenital Infection with Cytomegalovirus Presented as Blueberry Muffin Syndrome in a Preterm Newborn: A Case Report 先天性巨细胞病毒感染表现为早产新生儿蓝莓松饼综合征1例报告

Austin Journal of Dermatology Pub Date : 2022-07-13 DOI: 10.26420/austinjdermatolog.2022.1102

F. R.

引用次数: 0

Malignancy-Associated Generalized Granuloma Annulare in a Japanese Patient with Stomach Cancer and Diabetes Mellitus 恶性相关的广泛性肉芽肿环状日本胃癌合并糖尿病患者

Austin Journal of Dermatology Pub Date : 2022-02-22 DOI: 10.26420/austinjdermatolog.2022.1101

Yokoyama K, Ikeda T, K. T

引用次数: 0

Eosinophilic Dermatosis of Hematological Malignancy Mimicking Wells Syndrome 嗜酸性粒细胞皮肤病的血液恶性肿瘤模拟威尔斯综合征

Austin Journal of Dermatology Pub Date : 2022-01-05 DOI: 10.26420/austinjdermatolog.2022.1100

Shah Ma, Khamdan Fa, Khamdan Ma, Alkhayyat Rmh

引用次数: 0

Bacteremia in Stevens Johnson Syndrome and Toxic Epidermal Necrolysis: Main Pathogens and Risk Factors: A Mini Review 史蒂文斯约翰逊综合征和中毒性表皮坏死松解的菌血症:主要病原体和危险因素:一个小综述

Austin Journal of Dermatology Pub Date : 2021-10-26 DOI: 10.26420/austinjdermatolog.2021.1099

Guerrero-Putz Md, Gomez-Flores M, Ocampo-Candiani J, Alba-Rojas E

{"title":"Bacteremia in Stevens Johnson Syndrome and Toxic Epidermal Necrolysis: Main Pathogens and Risk Factors: A Mini Review","authors":"Guerrero-Putz Md, Gomez-Flores M, Ocampo-Candiani J, Alba-Rojas E","doi":"10.26420/austinjdermatolog.2021.1099","DOIUrl":"https://doi.org/10.26420/austinjdermatolog.2021.1099","url":null,"abstract":"Stevens Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) are hypersensitivity reaction, mainly to drugs, characterized by skin detachment. They are dermatological emergencies, and bacteremia is the main cause death, especially in patients with extensive cutaneous involvement. We reviewed and summarized the large retrospective studies that focused on the risk factors and main pathogens involved in patients with SJS and TEN who developed bacteremia. Our results showed that the risk factors include a Total Body Surface Area (TBSA) higher than 10%, higher Severity-of-Illness Score For Toxic Epidermal Necrolysis (SCORTEN), hypertension, previous opiate use, White Blood Cells (WBC) > 10000/mL; C-Reactive Protein (CRP) > 100mg/mL; procalcitonin (PCT) ≥ 1μg/L; and skin colonization with P. aeruginosa, S. aureus, and methicillin-resistant S. aureus (MRSA). The most frequently isolated pathogens from blood cultures were S. aureus, E. faecalis, P. aeruginosa, Enterobacter spp, and A. baumannii. The identification and consideration of these variables on each patient with SJS and TEN could result in an earlier diagnosis, proper management and even prevention of bacteremia in this population.","PeriodicalId":247251,"journal":{"name":"Austin Journal of Dermatology","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116809796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Psoriasis Exacerbation Following COVID-19 Mrna Vaccination in an Elderly Patient 老年患者接种COVID-19 Mrna后银屑病加重

Austin Journal of Dermatology Pub Date : 2021-10-13 DOI: 10.26420/austinjdermatolog.2021.1098

Gatzka Mv, C. P., Czech Wj

引用次数: 0

Epidermodysplasia Verruciformis: A Case Report and a Brief Review 疣状表皮发育不良1例报告及简要回顾

Austin Journal of Dermatology Pub Date : 2021-07-22 DOI: 10.26420/austinjdermatolog.2021.1096

Bouabdella S, A. S., Zizi N, Dikhaye S

引用次数: 0

Pre-Procedural Patient Anxiety in Dermatologic Procedures: A Cross-Sectional Study of Dermatologists 皮肤科手术前患者焦虑:皮肤科医生的横断面研究

Austin Journal of Dermatology Pub Date : 2021-07-22 DOI: 10.26420/austinjdermatolog.2021.1097

N. S, M. A, Yousif J, Warbasse E, Potts G

引用次数: 0

Whole Body FDG PET-CT in the Evaluation and Management of Cardiac Sarcoidosis and Isolated Cardiac Sarcoidosis 全身FDG PET-CT对心脏结节病和孤立性心脏结节病的评价和治疗

Austin Journal of Dermatology Pub Date : 2021-02-01 DOI: 10.26420/austinjdermatolog.2021.1094

D. M

{"title":"Whole Body FDG PET-CT in the Evaluation and Management of Cardiac Sarcoidosis and Isolated Cardiac Sarcoidosis","authors":"D. M","doi":"10.26420/austinjdermatolog.2021.1094","DOIUrl":"https://doi.org/10.26420/austinjdermatolog.2021.1094","url":null,"abstract":"Introduction Sarcoidosis is a multisystem inflammatory disease defined histologically by the formation of non-caseating granulomas. Cardiac involvement can be seen in up to 5% of cases [1]. These patients are at a high risk for major cardiac events [1]. Diagnosing and monitoring Cardiac Sarcoidosis (CS) is not trivial but can be currently accomplished by a combination of cardiac MRI and cardiac FDG PET-CT scanning [2]. With appropriate patient preparation, cardiac FDG PET has a high sensitivity for detecting cardiac lesions but also extra-cardiac lesions and for monitoring the efficacy of treatment. Discussion Current standard clinical practice consists of acquiring dedicated, limited field of view cardiac FDG PET scans. This would cover the heart and immediately adjacent thoracic structures. Although this is of great value and used with great success to diagnose and monitor cardiac sarcoidosis, it fails to assess the patient’s disease in a holistic manner. Still with this limited field of view, several reports including ours have described a high rate of extra-cardiac findings. We reviewed a series of sixty-five PET-CT scans of 54 patients referred for CS evaluation. These were performed between September 2010 and April 2013 at Yale New Haven Hospital and we found extra-cardiac findings were present in 92.3% of scans (n=60). Overall disease distribution is summarized in (Table 1). Highlight some of these extra-cardiac findings (Figures 1-4). 52.3% of these patients were asymptomatic at the time of the scan. CS was diagnosed in 50.8% of patients (n=33). All the patients (100%) with CS had extra-cardiac findings. Additionally, extra-cardiac findings were present in 48.3% of the scans when there was no cardiac involvement. In our cohort, we had no cases of Isolated Cardiac Sarcoidosis (ICS).","PeriodicalId":247251,"journal":{"name":"Austin Journal of Dermatology","volume":"59 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115743677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

FDG PET Scanning in Hemophagocytic Lymphohistiocytosis 吞噬性淋巴组织细胞病的FDG PET扫描

Austin Journal of Dermatology Pub Date : 2021-01-25 DOI: 10.26420/austinjdermatolog.2021.1095

D. M

{"title":"FDG PET Scanning in Hemophagocytic Lymphohistiocytosis","authors":"D. M","doi":"10.26420/austinjdermatolog.2021.1095","DOIUrl":"https://doi.org/10.26420/austinjdermatolog.2021.1095","url":null,"abstract":"Hemophagocytic Lymphohistiocytosis (HLH) is a rare disorder. It progresses rapidly and can be life-threatening. Prompt initiation of treatment is critical for survival. Untreated, patients survive only a few months. These patients have multisystem involvement and may develop multi-organ failure. The goal of therapy for patients with HLH is to suppress life-threatening inflammation. After induction, patients who are recovering are weaned off therapy, while those who are not improving are continued on therapy as a potential bridge to stem cell transplantation. Monitoring treatment response is critical as treatment escalation may be warranted if the patient is not improving. The distinction between chemotherapy toxicity and worsening disease may be difficult to make clinically. Quite a variety of clinical, biochemical and immunological biomarkers are used at diagnosis and to assess treatment response. The response to initial therapy is a major factor in determining the need for additional therapy including Hematopoietic Cell Transplant (HCT). Response to induction therapy is monitored by assessing the patient clinically and using HLH disease-specific markers. Although this approach has some success, it is sometimes confounded by a new infection or treatment toxicity. Imaging can provide an additional layer of accuracy in the initial evaluation of HLH patients as well as their monitoring and follow-up. 18F-FDG PET scans are highly sensitive and can be quite helpful in the management of these patients (Figure 1).","PeriodicalId":247251,"journal":{"name":"Austin Journal of Dermatology","volume":"121 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127289576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Serum Interleukin 17 and Interleukin 33 in Vitiligo Egyptian Patients 埃及白癜风患者血清白细胞介素17和白细胞介素33的研究

Austin Journal of Dermatology Pub Date : 2021-01-14 DOI: 10.26420/austinjdermatolog.2021.1093

Ibrahim ElGhareeb M, E. S, Fathi M, K. N, Gado M

{"title":"Serum Interleukin 17 and Interleukin 33 in Vitiligo Egyptian Patients","authors":"Ibrahim ElGhareeb M, E. S, Fathi M, K. N, Gado M","doi":"10.26420/austinjdermatolog.2021.1093","DOIUrl":"https://doi.org/10.26420/austinjdermatolog.2021.1093","url":null,"abstract":"Background: Vitiligo is an acquired depigmented disorder characterized by milky-white macules in the skin. Interleukin-17 has important role in autoimmune diseases development like vitiligo. Interleukin-33 is released after tissue damage or cell death. It may reflect recent disease activity. Aim: To measure serum levels of IL17 and IL-33 in vitiligo patients and to assess their relationship with disease activity. Methods: Levels of IL17 and IL-33 in serum samples taken from 21 healthy normal subjects and 21 vitiligo patients were measured by ELISA. All the patients were subjected to careful history taking , general examination and local examination to assess extent ,activity of vitiligo and VASI score. Results: IL17 and IL-33 serum levels were highly statistically significant increase in patients with vitiligo than the normal control subjects(p≤0.001). Their levels were related to disease activity and the extent of the disease. Interleukin 17 serum levels were positively correlated with IL-33 serum levels. Conclusion: Increased serum levels of IL-17 and IL-33 in vitiligo patients and their levels were related to disease activity and the extent of the disease indicating that IL-17 and IL-33 may play a role in the pathogenesis of vitiligo.","PeriodicalId":247251,"journal":{"name":"Austin Journal of Dermatology","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121930788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0