NCT Neumología y Cirugía de Tórax最新文献

{"title":"Enfermedad COVID-19 en adultos jóvenes mexicanos hospitalizados","authors":"Norma Angélica Téllez-Navarrete, Omar Barreto-Rodríguez, Oscar Gabriel Jiménez-Cabrera, Carla Paola Sánchez-Ríos","doi":"10.35366/100991","DOIUrl":"https://doi.org/10.35366/100991","url":null,"abstract":"Introduction: The literature suggests that the behavior of SARS-CoV-2 infection in young people is different. COVID-19 has been reported to be less frequent and less severe yet the evidence remains contrasting. This study had the objective of describing the COVID-19 disease in hospitalized Mexican youth. Material and methods: A retrospective study was carried out in 102 patients with COVID-19 admitted to the National Institute of Respiratory Diseases Ismael Cosío Villegas and the ISSEMyM Toluca State of Mexico Medical Center in the period from March to May 2020. They were classified according to age, 51 patients in the group of young adults <35 years and 51 adults older than 35 years. The clinical characteristics between the groups and their association with decreased severity of illness and death were compared. Results: In the group of young people (<35 years) the saturation of O2 at admission was 86% IQR (74-91). 66% (n = 34) presented lymphopenia on admission. The percentage of obesity in young people was similar to that of adults (43% versus 41%). The degree of severity was mild in 27.5% (n = 14), moderate in 45% (n = 23) and severe/critical in 27.5% (n = 14). This group also presented lower degrees of tachypnea, severity of COVID-19 and lethality due to SARS-CoV-2 infection when compared to adults (15% versus 45% p <0.05). At hospital admission, D-dimer values were lower in this group (0.69 versus 1.01 µg/mL) and serum albumin was higher (3.77 versus 3.3 mg/dL) compared with the values in adults. The neutrophil/lymphocyte ratio and platelets/lymphocytes were found as possible predictive biomarkers of deterioration by COVID-19 with an OR of 8.03 and 3.6, respectively. Conclusion: Young adults with COVID-19 who warrant hospitalization have a high percentage of obesity. They have a higher amount of initial albumin, and lower levels of D-dimer with symptoms that are frequently mild-moderate on admission and less lethal compared to hospitalized adult patients. © 2021, Instituto Nacional de Enfermedades Respiratorias. All rights reserved.","PeriodicalId":246416,"journal":{"name":"NCT Neumología y Cirugía de Tórax","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123776518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fármacos de reposicionamiento y fármacos específicos en fase preclínica para la COVID-19","authors":"Carlos Francisco Cabrera-Sánchez, J. Y. Sánchez-Godínez, Y. González","doi":"10.35366/103451","DOIUrl":"https://doi.org/10.35366/103451","url":null,"abstract":"@https://dx.doi.org/00000000000 @ Neumol Cir Torax. 2021; 80 (4): 258-268 RESUMEN. El reposicionamiento de fármacos es una actividad que se realiza comúnmente por los laboratorios, y consiste en el uso comercial de un fármaco para un fin distinto para el que fue investigado o aprobado. En 2019 inició la pandemia de la COVID-19 causada por un nuevo virus, el SARS-CoV-2, un virus para el cual la población humana no tiene inmunidad, y tampoco se cuenta con un tratamiento eficaz. Como primera estrategia para tratar a los pacientes gravemente enfermos, se reposicionaron los fármacos que mostraban al menos teóricamente ser efectivos contra el SARS-CoV-2 para uso de emergencia. Una vez que se tuvieron resultados de los estudios clínicos, se evaluó su efectividad en la prevención de casos graves y/o mortales, si el fármaco mostraba una efectividad significativa, la Organización Mundial de la Salud (OMS) emitió la recomendación correspondiente para su uso, de lo contrario se emite la alerta de suspender su uso para la COVID-19. En esta revisión se describen los fármacos que se han reposicionado siguiendo este proceso así como los nuevos fármacos específicos para el SARS-CoV-2 que se encuentran en fase experimental y preclínica.","PeriodicalId":246416,"journal":{"name":"NCT Neumología y Cirugía de Tórax","volume":"78 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122756277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cuarta Reunión Anual de la Sociedad Latinoamericana de Fisiología Respiratoria 2020. Premiación de Trabajos libres","authors":"","doi":"10.35366/103458","DOIUrl":"https://doi.org/10.35366/103458","url":null,"abstract":"","PeriodicalId":246416,"journal":{"name":"NCT Neumología y Cirugía de Tórax","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131759755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluación educativa en tiempo de pandemia de COVID-19. ¿Cómo cambió en los ámbitos hospitalarios? Una propuesta","authors":"Juan Carlos Vázquez-Minero, María de Jesús Villalba-Calderón, Arturo Chávez-Tinoco","doi":"10.35366/102481","DOIUrl":"https://doi.org/10.35366/102481","url":null,"abstract":"","PeriodicalId":246416,"journal":{"name":"NCT Neumología y Cirugía de Tórax","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128357165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ansiedad en familiares de pacientes con COVID-19 hospitalizados en el Instituto Nacional de Enfermedades Respiratorias","authors":"Gabriela Lara-Rivas, Eryka Urdapilleta-Herrera, Carlos Antonio Ruiz-Aguilar","doi":"10.35366/100990","DOIUrl":"https://doi.org/10.35366/100990","url":null,"abstract":"Introduction: The SARS-CoV-2 pandemic has had impact on people’s mental health. The family or caregiver of hospitalized patients are considered a vulnerable population, who do not usually receive the necessary mental health care, and due to the current confinement, they have to be apart from their relative interned for COVID-19, making their situation harder. Objective: To know the anxiety symptoms of the relatives of patients in hospital for such disease. Material and methods: Exploratory, descriptive and ambispective study on relatives of hospitalized patients for COVID-19 at the National Institute of Respiratory Diseases in Mexico City, interviewed through the questionnaire GAD-7, from May 15 to September 30, 2020. A descriptive analysis was carried out and sociodemographic variables were collected for their correlation. Results: A sample of 234 family members was analyzed, with an average age of 42 years, the mean of anxiety symptoms was at seven, corresponding to a diagnosis of mild anxiety. Of them, 73.5% reported mild symptomatology and 26.5% moderate-severe. Women have more moderate-severe symptomatology compared to men (p < 0.05). Conclusions: Almost a third of the family members reported mild or severe anxiety symptoms. These results are very important because anxiety could influence the decisions they make about the treatment of their hospitalized patients for COVID-19. Developing strategies to give them psychological support could be the most important goal throughout the pandemic. © 2021, Instituto Nacional de Enfermedades Respiratorias. All rights reserved.","PeriodicalId":246416,"journal":{"name":"NCT Neumología y Cirugía de Tórax","volume":"250 7","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120941374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perforación faringoesofágica espontánea complicada con absceso mediastinal en niño","authors":"R. Sancho-Hernández, L. Solorio-Rodríguez, Lourdes Mascareñas-Martínez, José Ariel Castillo-Moguel","doi":"10.35366/97967","DOIUrl":"https://doi.org/10.35366/97967","url":null,"abstract":". Introduction: Pharyngo-esophageal perforation represents a critical condition with high morbidity and mortality rates associated with a late diagnosis, current recommendations advocate conservative treatment, this report describes the usefulness of conservative and endoscopic treatment of a patient with spontaneous pharyng-esophageal perforation complicated with mediastinal abscess, the benefit of tissue adhesives in the closure of a residual fístula is detailed and a review of the literature applied to the pediatric population is proposed. Description of the case: A 16-year-old female adolescent who attended the emergency department with dysphagia, fever and subcutaneous emphysema of the neck and thorax, in esophagography and tomography, an upper esophageal perforation and the presence of a mediastinal abscess were corroborated, as the trans endoscopic route was considered insufficient for the patient a drainage of the septate mediastinal cavity and a left posterior cervical approach was decided, allowing mechanical debridement and drainage of 600 ml of purulent material; with clinical improvement, it persists with a pharyngo-cutaneous-mediastinal fístula and the decision was made to instill a solution of tissue adhesive inside the entire double fistulous tract and successful successful closure with a favorable evolution. Conclusions: An early recognition of pharyngoesophageal perforation, as well as aggressive debridement and appropriate drainage, allow tissue adhesives such as cyanoacrylate to promote successful and low morbidity closure by trans endoscopic in secondary sequelae and fistulas.","PeriodicalId":246416,"journal":{"name":"NCT Neumología y Cirugía de Tórax","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129770133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prueba de reto bronquial con ejercicio. Recomendaciones y procedimiento","authors":"Laura Gochicoa-Rangel, J. Vázquez-García, Claudia Vargas-Domínguez, Mónica Velázquez-Uncal, Ramiro Martínez-Andrade, Isabel Salas-Escamilla, Anaid Bautista-Bernal, Mónica Silva-Cerón, R. Mejía-Alfaro, Luis Torre-Bouscoulet","doi":"10.35366/NTS192M","DOIUrl":"https://doi.org/10.35366/NTS192M","url":null,"abstract":"The bronchial challenge test with exercise (BCTE) is designed to evaluate the effect of exercise on spirometric parameters, as it makes it possible to explore whether exercise induces bronchial obstruction. This test is particularly useful in those patients that present symptoms of bronchial obstruction but whose at-rest spirometry is normal, and in others who present respiratory symptoms only while doing exercise. Although general recommendations for conducting BCTE have been published, we consider that certain aspects related to the technique of test performance and interpretation of results are not suffi ciently well defi ned. With the goal of improving quality control and facilitating test performance, this article reviews the existing international recommendations related to this procedure and presents guidelines that may contribute to achieving a better standardization process.","PeriodicalId":246416,"journal":{"name":"NCT Neumología y Cirugía de Tórax","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133842328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Experiencia en el tratamiento conservador y quirúrgico en niños con secuelas y complicaciones enfisematosas secundaria a ventilación mecánica: serie de casos y revisión de la literatura","authors":"R. Sancho-Hernández, Francisco J. Cuevas-Schacht, Gabriel Gutiérrez-Morales, A. Alva-Chaire, L. Solorio-Rodríguez","doi":"10.35366/NT191B","DOIUrl":"https://doi.org/10.35366/NT191B","url":null,"abstract":"), ) ). ABSTRACT. Introduction: Interstitial emphysematous disease (IED) is a group of conditions that affect ectopic air trapping in the pulmonary interstitium of the child in the context of an infectious process and secondary damage generated by mechanical ventilation; a functional-radiological-clinical classification that allows a diagnostic and therapeutic approach is proposed. Methods: A descriptive, retrospective and observational study in cases series with 13 patients with diagnoses confirmed by pathology IED and radiological and functional evaluation. They were divided into 3 groups: interstitial lobar emphysema acquired (ILEA), neonatal interstitial emphysema (NIE) and interstitial emphysema and barotrauma (IEB), congenital causes were excluded, infectious and mechanical ventilation factors, response to conservative and surgical approaches, mortality and complications were investigated. Results: In ILEA group: 3 persistent bronchiolitis obliterans diagnosed interstitial emphysema, pulmonary resection was performed with satisfactory outcome and other diagnostic biopsy with insidious evolution of their hypertensive vascular disease; NIE: 4, 3 lobectomy eradicated hypertension and pulmonary short circuit and progression broncodisplasia avoided, and another responded to conservative management with high frequency ventilation; IEB: 6 were treated with pleural drainage and represent the largest group lethality associated with pneumonia and a high ventilatory pressures. Conclusions: This classification allows a diagnostic and therapeutic orientation: ILEA and NIE group forecasts show improvement with lung resection if conservative options have failed; In the EIB group, and mild ventilatory are","PeriodicalId":246416,"journal":{"name":"NCT Neumología y Cirugía de Tórax","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132087354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tratamiento ambulatorio de COVID-19: un aprendizaje pendiente","authors":"Cristóbal Guadarrama-Pérez","doi":"10.35366/108492","DOIUrl":"https://doi.org/10.35366/108492","url":null,"abstract":"","PeriodicalId":246416,"journal":{"name":"NCT Neumología y Cirugía de Tórax","volume":"144 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116366994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"La clínica en la hipertensión pulmonar del adulto","authors":"R. A. Flores-Franco, Daniel Arturo Frías-Fierro","doi":"10.35366/nt193j","DOIUrl":"https://doi.org/10.35366/nt193j","url":null,"abstract":"RESUMEN. A pesar de los avances tecnológicos para el diagnóstico de la hipertensión pulmonar, la historia clínica y la exploración física aún se consideran fundamentales como método de escrutinio siempre y cuando se dominen los aspectos teóricos, sus fundamentos y sus limitaciones. Con la identificación de los factores de riesgo, la exclusión de aquellas entidades que forman parte del diagnóstico diferencial, una adecuada auscultación y el análisis del conjunto de variables clínicas obtenidas, se provee de importantes pistas que pudieran auxiliar en la detección lo más oportunamente posible de la enfermedad o contribuir en el seguimiento de estos pacientes.","PeriodicalId":246416,"journal":{"name":"NCT Neumología y Cirugía de Tórax","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134633905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}