Vita Kusuma Rahmawati, Mauliya Sri Sukmawati Wahyudi, Dwi Ayu Novinda Sari
{"title":"Atrial Fibrillation Detected After Acute Ischemic Stroke","authors":"Vita Kusuma Rahmawati, Mauliya Sri Sukmawati Wahyudi, Dwi Ayu Novinda Sari","doi":"10.19184/ams.v8i3.34235","DOIUrl":"https://doi.org/10.19184/ams.v8i3.34235","url":null,"abstract":"Atrial fibrillation (AF) increases 4-5 times incidence of cardiac embolic stroke. In contrast, as many as 70% of AF cases can be detected in stroke within three days of onset, and this can affect the patient's prognosis. This case report describes the causal pathophysiology of AF and acute stroke and identifies the associated risk factors. Case 1 is a 44-year-old woman, acute stroke with acute decrease level of consciousness. The patient came with status epilepticus and a hypertensive emergency. Obtained a history of stroke, uncontrolled hypertension, and myocardial infarction. Initial Score National Institutes of Health Stroke Scale (NIHSS) was 33 and CHA2DS2-VASc was 5. Investigation non-contrast head Computed Tomography (CT) scan showed no bleeding and echocardiography (ECG) showed AF with rapid ventricular response. The patient died after 3 days of treatment. Case 2 is an 83-year-old woman, acute stroke with acute decrease level of consciousness and right motor lateralization. There was a history of hypertension and stroke with left hemiparesis. The initial NIHSS was 28 and CHA2DS2-VASc was 6. Investigations non-contrast head CT scan showed no bleeding and ECG showed AF with normal ventricular response. The patient was discharged from the hospital after being treated for 22 days with NIHSS of 20. Several risk factors for post-stroke AF are elderly, hypertension, subtype of ischemic stroke, prior stroke, and comorbidities such as DM and hypertension. Post-stroke AF can occur because of changes in heart rhythm through autonomic disorders, increased plasma catecholamine levels, and inflammatory reactions. Early Recognition of risk factors, focusing on patients at higher risk of AF detected after stroke becomes important for comprehensive management of stroke with AF. \u0000Keywords: acute ischemic stroke, atrial fibrillation, CHA2DS2-VASc score, risk factors.","PeriodicalId":246242,"journal":{"name":"Journal of Agromedicine and Medical Sciences","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132006606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pipiet Wulandari, Athiyah Fi Ramadani, S. Suryono, Ali Santosa
{"title":"Effective Dose of Moringa Leaf Extract (Moringa oleifera Lamk.) to Descrease Total Cholesterol Levels in Streptozotocin-Induced Male Wistar Rats","authors":"Pipiet Wulandari, Athiyah Fi Ramadani, S. Suryono, Ali Santosa","doi":"10.19184/ams.v8i2.27402","DOIUrl":"https://doi.org/10.19184/ams.v8i2.27402","url":null,"abstract":"Lipid metabolic disorder in hyperlipidemia characterized by an increase in the entire lipid profile in the blood. In 2019, the global prevalence of hyperlipidemia was 64.2%. Many patients with diabetes mellitus developed to hyperlipidemia. Diabetes mellitus characterized by hyperglycemia that caused by insulin production defects or decreased insulin resistance. Hyperglycemia in this study resulted from the injection of a streptozotocin dose of 45mg/kgBB intraperitoneally. Hyperglycemia could induced hyperlipidemia. It is due to increased lipid synthesis resulting in overproduction of HMG-CoA and ROS. Moringa leaves contain active substances such as flavonoids and vitamin C that act as antioxidants. This study was conducted to find out the effective dose of moringa leaf extract to lower the total cholesterol levels of male Wistar rats induced by streptozotocin. The dose of moringa leaf extract was divided into 5 groups, namely 62.5 mg/kgBW, 125 mg/kgBW, 250 mg/kgBW, 500 mg/kgBW, and 1000 mg/kgBW. The analysis of the data in this study was a Pearson correlation test that showed p< 0.05. It demonstrated that administration of moringa leaf extract correlated with decreased cholesterol levels of male Wistar rats. The effective dose of moringa leaf extract was calculated using a linear regression test. The equation obtained from the regression test was y= 0.0739x + 153.59, so the dose of moringa leaf extract that effectively lowers the total cholesterol levels of male Wistar rats was 528.96 mg/kgBW. \u0000Keywords: hyperlipidemia, diabetes mellitus, cholesterol, Moringa oleifera Lamk., streptozotocin","PeriodicalId":246242,"journal":{"name":"Journal of Agromedicine and Medical Sciences","volume":"116 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126628916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Rachmawati, Ranindya Putri Cipta Indraswari, E. N. Sakinah
{"title":"The Correlation Between Mother's Knowledge about Complementary Feeding with The Incidence of Stunting in Toddlers Under Two in Mayang, Jember","authors":"D. Rachmawati, Ranindya Putri Cipta Indraswari, E. N. Sakinah","doi":"10.19184/ams.v8i2.25606","DOIUrl":"https://doi.org/10.19184/ams.v8i2.25606","url":null,"abstract":"Stunting is a condition of toddlers who have a height-for-age less than -2 SD WHO Z-score. The period from a newborn until two years is also known as the golden period. Nutrition obtained after birth affects the growth and development of them. Complementary feeding was given when they were 6 months old. The level of mother's knowledge about complementary foods has an impact on complementary feeding. Inappropriate complementary feeding can lead to stunting. The research objective was to determine the correlation between mother's knowledge about complementary feeding and the incidence of stunting in toddlers under two in Mayang. The research was an analytical observational with a cross sectional study design. The sample was 90 respondents taken using consecutive sampling method. Data collection using a questionnaire on the mother and using height-for-age data from the toddlers. Statistical test using the Spearman test, showed that there was a significant correlation between the level of mother's knowledge about complementary feeding and the incidence of stunting (p=0.024.; rho=-0.238). Due to this result, we recommend continuous health promotion and education among mothers to decrease the risk of stunting in their children. \u0000Keywords: stunting, complementary feeding, toddlers under two, mother’s knowledge","PeriodicalId":246242,"journal":{"name":"Journal of Agromedicine and Medical Sciences","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126009144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"High Degree of Parasitemia Induces Placental Hypoxia and Low Birth Weight","authors":"N. Indriana, Z. Rahmah, Alvi Milliana","doi":"10.19184/ams.v8i2.31243","DOIUrl":"https://doi.org/10.19184/ams.v8i2.31243","url":null,"abstract":"Placental malaria causes low fetal weight associated with infiltration of monocytes and parasites in the placenta resulting in placental hypoxia. Hypoxia is characterized by HIF expression. HIF-1α expression responds early to the occurrence of hypoxia (<24 hours) and HIF-2α promotes chronic hypoxia (>24 hours). There were two groups in this study, namely the control group (10 pregnant mice without Plasmodium berghei infection) and the treatment group (10 pregnant mice infected with Plasmodium berghei). Pregnant mice were operated on on the 18th day after mating. The degree of parasitemia was measured by Giemsa staining. Expression of HIF-1α and HIF-2α in placental tissue was measured by immunohistochemistry. Results by paired t test, HIF-1α expression in the placental tissue in the treatment group was higher than the control group (p=0.02), HIF-2α expression in the placental tissue was higher in the treatment group than in the control group (0, 01) the fetal weight in the treatment group was lower than in the control group (p=0.01). By using SEM analysis, the degree of parasitemia caused high expression of HIF-1α in placental tissue (tcount = 4.625, ttable = 1.96). High expression of HIF-2α in placental tissue (tcount = 2.672 ttable = 1.96). The degree of parasitemia causes low fetal weight (tcount = 27.764 ttable = 1.96). The results also showed that HIF-1 caused low birth weight (tcount = 2.376 ttable=1.96) also HIF-2α caused low fetal weight (tcount = 4.267 ≥ 1.96). Conclusions the degree of parasitemia causes high expression of HIF-1α and HIF-2α in placental tissue and low birth fetuses. Expression of HIF-1α and HIF-2 also causes low birth weight. \u0000Keywords: malaria in pregnancy, degree of parasitemia, HIF-1α , HIF-2α , birth weight","PeriodicalId":246242,"journal":{"name":"Journal of Agromedicine and Medical Sciences","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126035258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Sari, Dwi Handayani, Gita Dwi Prasasty, C. Anwar, F. Karim
{"title":"Correlation between the Use of Shared Goods with Pediculosis Capitis among Students in Pondok Pesantren Subulussalam Palembang","authors":"R. Sari, Dwi Handayani, Gita Dwi Prasasty, C. Anwar, F. Karim","doi":"10.19184/ams.v8i2.29113","DOIUrl":"https://doi.org/10.19184/ams.v8i2.29113","url":null,"abstract":"Pediculosis capitis is a parasitic infection caused by the parasite Pediculus humanus var. capitis, which commonly found in densely crowded areas such as boarding schools. It is possible to contract pediculosis capitis by coming into direct or indirect contact with sufferers' hair. The goal of this study was to assess the prevalence of pediculosis capitis in students at Pondok Pesantren Subulussalam Palembang, as well as the association between the use of shared goods and the occurrence of pediculosis capitis. This study is a cross-sectional observational analytic study including 116 students who live permanently in Pondok Pesantren Subulussalam Palembang. A questionnaire was used to collect data, as well as direct observation of hair samples. The Chi-Square test, Fisher's exact test, and logistic regression were used to examine the results. The findings revealed that 35.3% of people had pediculosis capitis, and that there was a significant association between the use of mattresses (p=0.007), combs (p=0.024), and shared veils (p=0.006) and the occurrence of pediculosis capitis. The use of combs (p=0.018) and shared veils (p=0.001) were the most influential variables on the occurrence of pediculosis capitis, according to the results of the logistic regression test. The spread of pediculosis capitis disease is predicted to be reduced and prevented with improved personal hygiene, environment sanitation, and treatment. \u0000Keywords: Pediculosis capitis, boarding schools, Subulussalam, shared goods","PeriodicalId":246242,"journal":{"name":"Journal of Agromedicine and Medical Sciences","volume":"85 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125499271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effectiveness of Kenikir (Cosmos caudatus Kunth.) Leaf Extract on Duodenal Epithelial Damage of Aspirin Induced Male White Rats (Rattus norvegicus)","authors":"Siti Alfina, Husnarika Febriani, S. Syukriah","doi":"10.19184/ams.v8i2.31304","DOIUrl":"https://doi.org/10.19184/ams.v8i2.31304","url":null,"abstract":"Aspirin or acetylsalicylic acid is one of the most common types of anti-inflammatory drugs used by people to relieve pain and inflammation. However, aspirin consumption can cause damage to the duodenal mucosal epithelium because it is acidic and inhibits the production of prostaglandins that are important in maintaining the mucosa. Duodenal damage due to aspirin consumption can be repaired using natural ingredients from plants with antioxidant and anti-ulcer effects, one of which is kenikir (Cosmos caudatus Kunth.) leaves. This study aims to determine the effectiveness of kenikir leaf extract against aspirin-induced histopathology and histomorphometry of the duodenum of male white rats. The research design used a completely randomized design (CRD) with 5 treatments and 5 replications. The treatments consisted of a normal group (feed and drink ad libitum), an aspirin group (induction of aspirin 200 mg/kgBW), and a treatment group with kenikir leaf extract at a dose of 700 mg/kgBW, 800 mg/kgBW, and 900 mg/kgBW. Preparation of histopathological preparations of the duodenum used the paraffin method with Hematoxylin-Eosin staining. Data were analyzed using one-way ANOVA and Duncan's follow-up test. The results of the histopathology study showed a significant difference (p<0.05) on the integrity score of duodenal mucosal epithelial cells. Histomorphometry had a significant effect on the height villi, basal width, apical width, and villous area (p<0.05). It can be concluded that administration of kenikir leaf extract at a dose of 900 mg/kgBW was most effective in improving the histopathology and duodenal histomorphometry of aspirin-induced male white rats. \u0000Keywords: aspirin, duodenum, kenikir (Cosmos caudatus Kunth.)","PeriodicalId":246242,"journal":{"name":"Journal of Agromedicine and Medical Sciences","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128208501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Christopher Kevin Susanto, Eva Rachmi, Muhammad Rizqan Khalidi
{"title":"Risk Factors of Postoperative Nausea and Vomiting on General Anesthesia in RSUD Abdul Wahab Sjahranie Samarinda","authors":"Christopher Kevin Susanto, Eva Rachmi, Muhammad Rizqan Khalidi","doi":"10.19184/ams.v8i2.29227","DOIUrl":"https://doi.org/10.19184/ams.v8i2.29227","url":null,"abstract":"Postoperative Nausea and Vomiting (PONV) is the nauseous feeling within 24 hours after surgery. PONV increases the risk of fluid and electrolyte imbalance, re-opening of the surgical wound, and aspiration of gastric fluid. This study aimed to analyze the effect of postoperative opioid administration, duration of anesthesia, type of surgery, and BMI on the incidence of nausea and vomiting after surgery under general anesthesia, at Abdul Wahab Sjahranie Hospital, Samarinda. The research design employed in this research was a retrospective cohort study. The number of samples was 92 patients. The results of the analysis showed an increased risk of PONV in underweight – normal BMI patients (1.45 times higher risk; p=0.035), patients who received postoperative opioids (1.64 times higher risk; p=0.005), patients who underwent surgery that was potentially stimulating the vagus nerve (1.52 times riskier; p=0.02), and patients with anesthetic duration of more than 2 hours (1.93 times greater risk; p=0.007). Therefore, it could be concluded that BMI, postoperative opioid use, type of surgery, and duration of anesthesia influenced PONV incident on the use of general anesthesia at RSUD Abdul Wahab Sjahranie, Samarinda. \u0000Keywords: postoperative nausea and vomiting, BMI, opioid after surgery, type of surgery, anesthesia duration","PeriodicalId":246242,"journal":{"name":"Journal of Agromedicine and Medical Sciences","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126123440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Komang Yunita Wiryaning Putri, N. K. Adji, Azham Purwandono, Muhammad Yudha Nugraha, Salsabila Maula Zalfa El Hamzah
{"title":"A Case Report Symptoms Improvement of Cerebral Venous Sinus Thrombosis","authors":"Komang Yunita Wiryaning Putri, N. K. Adji, Azham Purwandono, Muhammad Yudha Nugraha, Salsabila Maula Zalfa El Hamzah","doi":"10.19184/ams.v8i2.30193","DOIUrl":"https://doi.org/10.19184/ams.v8i2.30193","url":null,"abstract":"Cerebral venous sinus thrombosis (CVT) is a rare cause of stroke, a life-threatening disorder that occurs in approximately 0,5-1% of all stroke incidents. Various clinical presentations, risk factors, and neuroimaging findings of this disease may cause a delay in the early diagnosis and treatment of CVT. We discuss a case of a 34-year-old female who was admitted to the emergency room (ER) with the onset of a generalized tonic-clonic seizure with a progressive headache in the occipitotemporal region. Based on head CT, there was multiple hyperdense and cerebral venous infarction in the posterior left parietal lobe. D-dimer evaluation, there was an increasing level of D-dimer (>10.000 ng/mL). The patient was treated with the primary therapy heparin. After 15 days of being hospitalized, the patient was discharged without any sequelae. \u0000Keywords: CVT, heparin, stroke","PeriodicalId":246242,"journal":{"name":"Journal of Agromedicine and Medical Sciences","volume":"104 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127975444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Case Report: Ranula and Sublingual Glands Extirpation as Intraoral Ranula Procedures","authors":"Rizki Saputra, Sukri Rahman, Pamelia Mayorita","doi":"10.19184/ams.v8i1.27612","DOIUrl":"https://doi.org/10.19184/ams.v8i1.27612","url":null,"abstract":"Ranula is a cystic lesion that develops from saliva extravasation caused by trauma to the sublingual gland or the occurrence of duct blockages. The ranula is divided into intraoral (simple ranula) and plunging ranula. There are several options of methods in the management of ranulas such as sclerotherapy, marsupialization, and extirpation with or without gland removal involved, incision and drainage with intraoral approach, excision lesions with the extra-oral approach. A case of ranula was reported in a girl aged 12 years diagnosed with intraoral ranula (simple ranula). Treatment is done by performing ranula extirpation accompanied by the removal of the sublingual gland and its ducts. The extirpation of the ranula followed by removal of the involved sublingual salivary gland gave satisfactory results with no recurrence until 1 year of follow-up on the management of intra-oral ranula. \u0000 \u0000Keywords: ranula, simple ranula, intraoral ranula","PeriodicalId":246242,"journal":{"name":"Journal of Agromedicine and Medical Sciences","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126275695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Case Report: Management of Chronic Supurative Otitis Media Cholesteatoma Type with Recurrent Brain Abscess Complication","authors":"Khairani Ayunanda Ikhlas, Y. Edward","doi":"10.19184/ams.v8i1.25338","DOIUrl":"https://doi.org/10.19184/ams.v8i1.25338","url":null,"abstract":"Introduction: Chronic suppurative otitis media is broadly defined as chronic inflammation that involved mucose of middle ear and mastoid air cells. The most commonly encountered intracranial complication from chronic suppurative otitis media is meningitis followed by brain abscess. Antibiotics are quite effective in early and late cerebritis stage. Surgical intervention is essential once the abscess’s capsule is formed. Case Report: Reported a case of a 22-year-old male diagnosed with chronic suppurative otitis media auris dextra suspected cholesteatoma type with cerebral abscess complications. The managements are cerebral abscess drainage followed by canal wall down mastoidectomy. In patient, Recurrent cerebral abscess formed. Conclusion: Chronic suppurative otitis media with complications of cerebral abscess is treated with abscess drainage if the abscess size is >2cm and followed by canal wall down mastoidectomy. Otogenic brain abscess due to chronic suppurative otitis media can occur repeatedly if abscess antibiotic therapy was/were inadequate \u0000Keywords: otogenic brain abscess, mastoidectomy, chronic suppurative otitis media, abscess drainage","PeriodicalId":246242,"journal":{"name":"Journal of Agromedicine and Medical Sciences","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131241340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}