International Journal of Advanced Health Science and Technology最新文献

{"title":"Can Osteoarthritis be Cured by Mesenchymal stem cells (MSCs)? A Literature Review","authors":"Mohamed Ziedan","doi":"10.35882/ijahst.v3i3.234","DOIUrl":"https://doi.org/10.35882/ijahst.v3i3.234","url":null,"abstract":"Osteoarthritis (OA) is a degenerative joint disease that affects millions of people worldwide. The disease frequently results in discomfort, edema, and stiffness, which can impair movement, make everyday tasks challenging, and even render a person disabled. Since osteoarthritis is presently incurable, researchers are working hard to find new treatments. Adult Mesenchymal stem cells (MSCs) are the most common stem cells used in the therapy of OA in clinical trials. They are simple to extract for researchers from bone marrow or adipose. Depending on the kind of tissue that contains them, MSCs can develop into cartilage, bone, muscle, tendon, ligaments, or fat. For this reason, scientists are researching MSCs in OA stem cell therapies. According to research, MSCs produce substances that promote healing and reduce pain. According to some research, they may aid in reducing pain, swelling, and loss of motion when injected into a joint. Researchers conduct an examination of articles that are in accordance with the issue to be studied. Articles used in literature review are obtained through the database of international journal providers through PubMed, we investigated clinical studies and discussed what happened in these clinical studies and the extent of the effectiveness of stem cells in treatment of osteoarthritis. Different patients have responded differently to this therapy. While some people have experienced pain others have not. Research is still required to determine whether stem cell therapies for OA are effective and why some people respond to the therapy more favorably than others.","PeriodicalId":245634,"journal":{"name":"International Journal of Advanced Health Science and Technology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136300710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Beyond the Hospital Walls: The Digital Transformation of Healthcare in the Digital Economy","authors":"Pongsakorn Limna","doi":"10.35882/ijahst.v3i2.244","DOIUrl":"https://doi.org/10.35882/ijahst.v3i2.244","url":null,"abstract":"This review article aimed to assess the existing literature regarding the digital transformation of healthcare in the digital economy. The review employed narrative synthesis, and the documentary method and content analysis were used via systematic review to analyze the data. The review of literature suggested that digital technologies have the potential to improve healthcare delivery, enhance patient outcomes, and increase access to healthcare services. The studies reviewed in this article demonstrate that digital transformation in healthcare can lead to improved efficiency, reduced costs, increased patient satisfaction, and better patient outcomes. The use of digital technologies such as telemedicine, electronic health records, wearables, and mobile health applications has already started to revolutionize healthcare delivery. However, the adoption of these technologies is not without its challenges, including privacy and security concerns, regulatory barriers, and resistance from healthcare providers. It is therefore important for healthcare organizations and policymakers to address these challenges and implement strategies to ensure the effective integration of digital technologies into the healthcare system. Overall, the findings suggest that the digital transformation of healthcare is a critical area of research that has the potential to significantly transform the healthcare industry and improve health outcomes for individuals and communities.","PeriodicalId":245634,"journal":{"name":"International Journal of Advanced Health Science and Technology","volume":"98 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115932423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"FACTORS AFFECTING THE SELECTION OF HEALTHY AND UNHEALTHY DIET BEHAVIOR IN ADOLESCENT GIRLS IN BANDAR LAMPUNG","authors":"Dian Isti Angraini, Asiah Nurul Izzah, K. Nisa, R. Zuraida","doi":"10.35882/ijahst.v3i2.216","DOIUrl":"https://doi.org/10.35882/ijahst.v3i2.216","url":null,"abstract":"\u0000Adolescence is a period of transitional development from children to adult women who are generally 10-21 years old. Adolescents has significant physical, psychosocial, and cognitive changes that can affect adolescent dietary behavior. The purpose of this study was to determine the effect of affecting factors on unhealthy dietary behavior in adolescent girls. This research is an analytic observational study, with a cross-sectional design approach using primary data, which was conducted from April to June 2022. The sample is 135 adolescent girls aged 15-21 years old taken using multistage random sampling who met the inclusion and exclusion criteria. The data was obtained by filling out the questionnaire and analyzed by using the chi square test. The results showed that 56.3% of respondents had unhealthy dietary behavior. The results of bivariate analysis showed that nutritional status (p = 0.000; PR = 2.072) and body image (p = 0.000; PR = 0.559) had an influence on unhealthy dietary behavior. Meanwhile, knowledge (p=0,227), age (p=0,158), pocket money (p=0,452) and peers (p = 0.120) had no influence on unhealthy dietary behavior. It can be concluded that there is an influence of nutritional status and body image factors on unhealthy diet behavior. \u0000","PeriodicalId":245634,"journal":{"name":"International Journal of Advanced Health Science and Technology","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128670797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Literature Review: Emergency Department Overcrowding and Its Solution","authors":"Yusron Amin, Haswita .","doi":"10.35882/ijahst.v3i2.221","DOIUrl":"https://doi.org/10.35882/ijahst.v3i2.221","url":null,"abstract":"Emergency department overcrowding was a obstacle of delivery healthcare services in emergency department. This condition was happened in emergency department when imbalance between enhancing of visiting patients number  and inadequately of staffing capacities and facilities. This condition had impact on decreasing quality of emergency department services including delaying medication time, increasing mortality rates, decreasing patient satisfaction, and hospital’ profit loss. Comprehensive understanding about emergency department overcrowding concept and its solution was needed to reduce incidents of ED overcrowding and its impact in healthcare services. The aim of the study was to provide evidance-based related to articles that discusses  emergency department overcrowding and its solution. Material and method: The study was literature review using database journal resources from PubMed, Proquest, ScienDirect, and Google scholar with using keyword emergency department (ED); Overcrowding. Inclusion criteria were 1) research articles that contained information about emergency department overcrowding: manifestation, causes, and impact, 2) Articles describing solution to reduce ED overcrowding, 3) All kinds that suitable with study design and review. Time filter between 2012-2022. The Result: from 9 selected articles (7 primary studies and 2 systematic reviews) showed that emergency department overcrowding was consisted of variables were  manifestation, causes, impact and solution.  Conclusion: Emergency department was caused by increasing patients number in ED and inadequate staffing capacity and equipment availability. ED overcrowding effected on patient services, healthcare delivery system proccess, and quality care. Recommendation: reducing incidents of ED overcrowding through identification of each causes factors, selecting intervention based on primary problem, strategy  to implementation and preparing of supporting resources.","PeriodicalId":245634,"journal":{"name":"International Journal of Advanced Health Science and Technology","volume":"61 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116782763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Therapeutic impact of Telomerase Inhibitor Imetelstat: A Literature Review","authors":"Mohamed Ziedan, Dina Salah, Maha Ayman","doi":"10.35882/ijahst.v3i2.238","DOIUrl":"https://doi.org/10.35882/ijahst.v3i2.238","url":null,"abstract":"The immortal phenotype of cancer cells is a significant trait, and in the vast majority of malignancies, the enzyme telomerase is essential for sustaining the cancer cells' limitless capacity for replication. The absence of telomerase expression and the lack of an immortal phenotype in normal adult tissues suggest that telomerase is a prospective therapeutic target for the treatment of a variety of tumor forms. At every cell division, telomeres will shrink if telomerase is not active. Apoptosis, cell senescence, and chromosomal instability are initiated when the telomeres become critically short. Telomeres are stabilized in the majority of rapidly expanding cancers by reactivating telomerase. In numerous tumor forms, it has been demonstrated that telomerase inhibition inhibits the development of cancer cells. Telomerase inhibitors have been discovered over the past 10 years as a result of substantial basic research into the mechanisms regulating telomeres, which may offer a potent, nearly universal cancer treatment approach. A short-chain oligonucleotide called imetelstat (GRN163L, Geron Corporation) has a high affinity and specificity for the RNA component of telomerase's template region (hTR or hTERC). Researchers conduct an examination of articles that are in accordance with the issue to be studied. Articles used in literature review are obtained through the database of international journal providers through PubMed, we investigated clinical studies and discussed what happened in these clinical studies and the extent of the effectiveness of imetelstat in treatment of cancer. Articles proved that imetelstat could enhance cancer treatment. Articles proved that Imetelstat is promising therapeutic agents for cancer treatment. In this review, we suggest that formulating and following treatment, Further studies are needed to determine the related mechanisms to enhance Imetelstat efficacy.","PeriodicalId":245634,"journal":{"name":"International Journal of Advanced Health Science and Technology","volume":"145 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127507969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of Giving Chocolate Drinks as Complementary Antidepressant Therapy in Pregnancy","authors":"Nining Mustika Ningrum, Farach Khanifah","doi":"10.35882/ijahst.v3i2.218","DOIUrl":"https://doi.org/10.35882/ijahst.v3i2.218","url":null,"abstract":"Pregnancy is a natural and physiological process that occurs in every woman. But often pregnant women experience anxiety and worry during pregnancy, this is a normal thing to happen during pregnancy. Symptoms of anxiety during pregnancy vary including anxiety, worry, and anxiety that are difficulty to control, irritability, irritability, difficulty concentrating, body muscles being painful and tense, lack of energy, disturbed sleep patterns, and disturbed rest patterns. Such anxiety can occur during pregnancy in both the I Trimester, II Trimester, and III Trimester. Although anxiety is normal in pregnancy, anxiety symptoms can occur on an ongoing basis if not addressed. The purpose of this study was to analyze the effectiveness of giving chocolate drinks as a complementary therapy to antidepressants in pregnancy. This type of research is quantitative analytics using a Quasi-Experimental research design with one group pre-post test design method using one treatment group. Free variables: Administration of chocolate drinks and bound variables: complementary therapy of antidepressants in pregnancy. The sample in this study was pregnant women who experienced anxiety in pregnancy both mild, moderate, severe, and even panic which matched the inclusion criteria of 124 people. Sampling using purposive sampling techniques. Instrument: HARS (Hamilton Anxiety Rating Scale) and Observation sheet. Data analysis using the Wilcoxon Test. The results showed that the anxiety of pregnant women before being given chocolate drinks was mostly 62.9% experienced mild anxiety, 35.5% experienced moderate anxiety and 1.6% experienced severe anxiety and after being given chocolate drink therapy more than half of the respondents namely 55.6% had no anxiety, 29% had mild anxiety, 15.4% had moderate anxiety and none of the respondents experienced severe anxiety and panic. So it can be concluded that giving chocolate drinks is effective as an antidepressant complementary therapy in reducing anxiety during pregnancy. It is hoped that all healthcare providers for pregnant women can recommend complementary therapies with herbal ingredients, especially chocolate as a therapy for reducing anxiety (antidepressants) during pregnancy","PeriodicalId":245634,"journal":{"name":"International Journal of Advanced Health Science and Technology","volume":"76 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114582380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chinese patients’ and family caregivers’ perception of care quality in Australian hospitals","authors":"Ying Yu, L. Xiao, D. Chamberlain","doi":"10.35882/ijahst.v3i2.243","DOIUrl":"https://doi.org/10.35882/ijahst.v3i2.243","url":null,"abstract":"Cultural diversity in the Australian population is significant. It challenges health professionals in Australia's acute and critical care settings to provide culturally competent care for ethnic minority patients. Chinese Australians are the largest ethnic minority group in Australia. However, their experiences in acute hospital settings remain largely unknown. Studies on this patient group are much needed to address the research gap and add research evidence on transcultural nursing for the international community. The aim of this study was to explore Chinese patients’ and their family caregivers’ perceptions of care quality in Australian hospitals. A qualitative descriptive study design was used in this study. Adult Chinese patients born in mainland China and who had an acute and critical care admission were recruited from metropolitan hospitals in South Australia in 2019 using the snowball method. Semi-structured interviews were conducted in Mandarin. Data were transcribed verbatim in simplified Chinese for thematic analysis. Results were translated to English and checked by a bilingual team member.Ten participants participated in the study. Four main themes were identified from the data analysis: 1) the feeling of being disoriented in the ICU; 2) desire for comfort; 3) lack of engagement in treatment and care plans; and 4) lack of participation in quality improvement feedback to the care system. Chinese people have unique cultural beliefs, communication patterns, and health-seeking behaviors. To provide culturally competent care for acute and critically ill Chinese patients, health professionals are required to incorporate transcultural nursing theory, knowledge, skills, and attitudes into everyday practice.","PeriodicalId":245634,"journal":{"name":"International Journal of Advanced Health Science and Technology","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117144188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of High Glycemic Modified Breakfast Menu on Increasing Learning Concentration of Junior High School Students Insan Cendekia Mandiri (ICM) Sarirogo – Sidoarjo","authors":"Nurul Hindaryani, Erlyna Jayeng, Mujayanto","doi":"10.35882/ijahst.v3i2.217","DOIUrl":"https://doi.org/10.35882/ijahst.v3i2.217","url":null,"abstract":"The nutritional adequacy of the Insan Cendekia Mandiri (ICM) junior high school students is obtained from the provision of food in the dormitory. One way to increase the acceptance of food intake organized by the boarding institution at the Insan Cendekia Mandiri Junior High School (ICM) is to modify the food menu. The provision of food doesn’t escape the standard portion for each individual so takes a portion of food that is by the RDA, so that it can be seen whether the individual needs of junior high school students have been met or not. This study aims to analyze the effect of modifying the menu of a high-glycemic meal on the acceptability and increase in learning concentration in students of SMP Insan Cendekia Mandiri in Sarirogo, Sidoarjo. This research method uses a pre-experimental design with a one-group pretest-posttest to determine the quality of the modification of the high-glycemic plate menu through the level of preference, acceptance of the increase in learning concentration of junior high school students at Insan Cendekia Mandiri (ICM) Sarirogo, Sidoarjo. The research sample was 37 junior high school students taken by simple random sampling using a formula to meet the inclusion and exclusion criteria. The variables in this study consisted of independent variables, namely modification of high glycemic prescriptions, the dependent variable was acceptance and learning concentration. The research instrument used is a 7-day menu cycle using organoleptic tests by conducting pre and posttest. The result is The breakfast menu from ICM has a lower glycemic index than the modified menu because of the ingredients used. There is a difference in the average energy value in the modified menu, which is 102.5 kcal compared to the breakfast menu from ICM, 2,94 grams of protein average higher than the breakfast menu on ICM, 10,9 grams of fat higher than the breakfast menu on ICM and then 10,76 grams of carbohydrate average lower than breakfast menu on ICM, and student concentration has increased because of the modified menu which has a high glycemic index.","PeriodicalId":245634,"journal":{"name":"International Journal of Advanced Health Science and Technology","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126005101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Strengthening global health security: lessons learnt from Indonesia's COVID-19 response","authors":"Dicky Budiman, Ernawanti, C. Chu","doi":"10.35882/ijahst.v3i2.230","DOIUrl":"https://doi.org/10.35882/ijahst.v3i2.230","url":null,"abstract":"The COVID-19 pandemic has revealed how poorly prepared the world is for a pandemic and how easily viruses spread in our interconnected world. Nevertheless, as infectious disease outbreaks become more frequent, it is hoped that national health security resources will be identified and strengthened. This will enable the nation to keep pace with spreading diseases and become more resilient to future threats. COVID-19 exposes strengths and weaknesses while also creating threats and opportunities. An analysis of the COVID-19 pandemic strategy was conducted using SWOT (Strengths, Weaknesses, Opportunities, and Threats) analysis based on Indonesia's experience with the response and countermeasures to COVID-19. The objective of this study is to analyse all the factors involved in the COVID-19 pandemic response so that lessons can be learned towards an effective public health emergency response. The results highlighted strengths, identified weaknesses, and provided recommendations for the future. This would be useful in responding to current threats to global health security and preparing for future ones.","PeriodicalId":245634,"journal":{"name":"International Journal of Advanced Health Science and Technology","volume":"49 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127009585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gadget With Children's Development Level Aged 4-6 Years Old in Kindergarten Handayani","authors":"Aida Novitasari, Ananda Zara Eka Putri, Enung Mardiyana Hidayat, Adin Muafiroh, Indriatie Indriatie","doi":"10.35882/ijahst.v3i2.188","DOIUrl":"https://doi.org/10.35882/ijahst.v3i2.188","url":null,"abstract":"digital era is experiencing very rapid development, especially the use of gadgets and this is in demand by all age levels, including pre-school age children. This has an impact on the level of child development in the form of delays in the level of development. The purpose of this study was to determine the relationship between game addiction and the level of development of children aged 4-6 years. The research design is cross sectional, the sampling technique used is a total sampling of 38 children at the Handayani Kindergarten in Surabaya, the independent variable is addiction to playing games, the dependent variable is the level of development of children aged 4-6 years. The analytical test used was spearman rho = 0.01. The results of the study show that there is a relationship between addiction to playing gadgets with the level of development of children aged 4-6 years with p value = 0.000 <0.05. Parents are expected to know the impact of gadget addiction and be able to provide education and assistance to their children when using gadgets, there are rules that must be agreed between children and parents regarding the duration of gadget use. Facilitates the game manually, introduces interesting traditional games.","PeriodicalId":245634,"journal":{"name":"International Journal of Advanced Health Science and Technology","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133960528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}