Chinese journal of otorhinolaryngology head and neck surgery最新文献

{"title":"[Endoscopic surgical treatment for primary hyperthyroidism with thyroid enlargement-10 years' experience at a single center].","authors":"P F Zhu, X Yu, N Yue, Y Du, L J Qin, Y Wang, P Wang","doi":"10.3760/cma.j.cn115330-20240424-00231","DOIUrl":"10.3760/cma.j.cn115330-20240424-00231","url":null,"abstract":"<p><p><b>Objective:</b> To investigate the feasibility and safety of endoscopic surgery for the treatment of primary hyperthyroidism with goiter. <b>Methods:</b> A total of 140 patients with primary hyperthyroidism and different degrees of thyroid enlargements were included who underwent endoscopic surgeries via a trans breast approach in the Second Affiliated Hospital of Zhejiang University School of Medicine from 2013 to 2023, including 137 females and 3 males, aged from 16 to 49 years old. Thirty-one cases had normal thyroid size, 25 cases had Grade Ⅰ enlargement, 56 cases had Grade Ⅱ enlargement, and 28 cases had Grade Ⅲ enlargement. Demographic characteristics, operative time, intraoperative blood loss, and postoperative complications were described, analyzed, and compared among groups. Student's <i>t</i>-test, Mann-Whitney <i>U</i> test, chi-square test, Fisher exact test or one-way analysis of variance (ANOVA) were used for statistical analyses. <b>Results:</b> The patients with Grade Ⅲ enlargement were younger compared to other groups (<i>F</i>=5.58, <i>P</i><0.01), and also had significantly longer operative time (<i>F</i>=2.81, <i>P</i>=0.04). The probability of conversion to open surgery in the Grade Ⅲ enlargement group was 10.7% (3/28), significantly higher than other groups (0/31, 0/25, 1/56, <i>χ</i>²=8.11, <i>P</i>=0.04). There were no significant differences among the four groups in terms of other demographic indicators and the incidences of postoperative complications (including recurrent laryngeal nerve injury, hypocalcemia, and surgical site infection). There was no significant difference in the probability of temporary hypoparathyroidism among the 4 groups. One patient with permanent hypoparathyroidism appeared respectively in the normal size group and Grade Ⅱ enlargement group. The average follow-up time was 4.2±3.7 years and 14 cases were lost to follow-up, and the patients had high satisfaction with\"no neck scar\"but with mild chest discomfort. <b>Conclusion:</b> The risk of endoscopic thyroid surgery in the treatment of primary hyperthyroidism with goiter is controllable, and patients with hyperthyroidism combined with Grade Ⅲ enlargement should be especially vigilant against the risk of conversion to open surgery.</p>","PeriodicalId":23987,"journal":{"name":"Chinese journal of otorhinolaryngology head and neck surgery","volume":"59 12","pages":"1325-1330"},"PeriodicalIF":0.0,"publicationDate":"2024-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142903784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Minutes of the 2024 China Rhinology Annual Meeting].","authors":"Q Xiu, G J Li, C D Meng, L W Sun, J M Liu, J C Sha, D D Zhu","doi":"10.3760/cma.j.cn115330-20240905-00509","DOIUrl":"https://doi.org/10.3760/cma.j.cn115330-20240905-00509","url":null,"abstract":"","PeriodicalId":23987,"journal":{"name":"Chinese journal of otorhinolaryngology head and neck surgery","volume":"59 12","pages":"1359-1363"},"PeriodicalIF":0.0,"publicationDate":"2024-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142903791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Quantitative analysis on characteristics of electromyography and evoked potential in normal laryngeal muscles].","authors":"Y H Lin, L Y Cheng, X Y Li, R Hu, W Xu","doi":"10.3760/cma.j.cn115330-20240717-00423","DOIUrl":"10.3760/cma.j.cn115330-20240717-00423","url":null,"abstract":"&lt;p&gt;&lt;p&gt;&lt;b&gt;Objective:&lt;/b&gt; To quantitatively analyze and explore the characteristics, influencing factors, reference value range, and variability of electromyography and nerve evoked potential in normal laryngeal muscles. &lt;b&gt;Methods:&lt;/b&gt; The study included 480 patients diagnosed with unilateral vocal fold immobility and underwent laryngeal electromyography (LEMG) at Beijing Tongren Hospital from June 2012 to June 2022, including 259 males and 221 females, with an average age of (44.4±14.9) years. Characteristics of the motor unit potential (MUP), recruitment pattern, and evoked potential in the thyroarytenoid muscle (TA), the posterior cricoarytenoid muscle (PCA) and the cricothyroid muscle (CT) of the normal side were analyzed, with the coefficient of variation (CV), reference value range of each parameter, and differences in different genders and age groups analyzed simultaneously. SPSS 24.0 software was used to analyze the data. &lt;b&gt;Results:&lt;/b&gt; The amplitudes of MUP in TA, PCA, and CT muscles were (129.52±24.95) μV, (240.67±88.25) μV, and (125.88±21.36) μV, respectively. The durations were (3.67±0.17) ms, (3.82±0.29) ms and (3.68±0.17) ms, respectively. The numbers of MUP phase were 1.94±0.28, 2.16±0.38, and 1.98±0.25, respectively. The per second numbers of turns in TA, PCA, and CT muscles were 565.76±193.88, 520.94±170.99, and 523.29±159.58, respectively. The amplitudes of the recruitment pattern were (1 038.00±368.65) μV, (1 269.91±434.75) μV, and (919.64±240.54) μV, respectively. The latencies of laryngeal nerve evoked potentials in TA, PCA, and CT muscles were (1.69±0.08) ms, (1.70±0.08) ms, and (1.70±0.11) ms, with durations of (6.20±1.30) ms, (6.41±1.34) ms, and (7.05±1.67) ms, respectively. The amplitudes were (7.42±3.62) mV, (6.05±2.83) mV, and (5.54±2.62) mV, respectively. The duration of MUP in male laryngeal muscles was higher than that in females, with statistical differences in TA (&lt;i&gt;t&lt;/i&gt;=5.70, &lt;i&gt;P&lt;/i&gt;&lt;0.01) and CT (&lt;i&gt;t&lt;/i&gt;=2.41, &lt;i&gt;P&lt;/i&gt;&lt;0.05) muscles, and the duration of evoked potentials was higher than that in females (TA: &lt;i&gt;t&lt;/i&gt;=3.63; PCA: &lt;i&gt;t&lt;/i&gt;=3.21; CT: &lt;i&gt;t&lt;/i&gt;=2.98; all &lt;i&gt;P&lt;/i&gt;&lt;0.01). The duration of PCA evoked potentials was weakly negatively correlated with age (&lt;i&gt;r&lt;/i&gt;=-0.17, &lt;i&gt;P&lt;/i&gt;&lt;0.01). The reference ranges for MUP duration in TA, PCA, and CT muscles were (3.30-3.90) ms, (3.40-4.30) ms, and (3.30-3.90) ms, respectively, and the latencies of the evoked potential were concentrated at 1.70 ms, the CVs were all less than 10%. &lt;b&gt;Conclusions:&lt;/b&gt; This study analyzes the parameters of MUP, recruitment pattern, and evoked potential in laryngeal muscles of the normal side in patients with unilateral vocal fold immobility, as well as the normal reference range. Among them, the duration of MUP and the latency of evoked potential are relatively small, which can be used as characteristic indicators for normal laryngeal muscles and nerves. MUP of TA and CT muscles in male patients, as well as the duration of all the e","PeriodicalId":23987,"journal":{"name":"Chinese journal of otorhinolaryngology head and neck surgery","volume":"59 ","pages":"1279-1285"},"PeriodicalIF":0.0,"publicationDate":"2024-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142855778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Neurogenic voice disorders].","authors":"L Xing, P Y Zhuang","doi":"10.3760/cma.j.cn115330-20240904-00353","DOIUrl":"10.3760/cma.j.cn115330-20240904-00353","url":null,"abstract":"","PeriodicalId":23987,"journal":{"name":"Chinese journal of otorhinolaryngology head and neck surgery","volume":"59 ","pages":"1393-1398"},"PeriodicalIF":0.0,"publicationDate":"2024-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142855776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Animal models of Meniere's disease].","authors":"S Y Shi, Z Q Guo, J Wang, E Tian, Y J Zhang, J Y Chen, Z H Zhou, J Q Guo, W J Kong, Y C Lyu, H Y Yao, S L Zhang","doi":"10.3760/cma.j.cn115330-20240523-00303","DOIUrl":"https://doi.org/10.3760/cma.j.cn115330-20240523-00303","url":null,"abstract":"","PeriodicalId":23987,"journal":{"name":"Chinese journal of otorhinolaryngology head and neck surgery","volume":"59 12","pages":"1382-1388"},"PeriodicalIF":0.0,"publicationDate":"2024-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142903778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Clinical characteristics and pathogenic variant analysis in a pedigree with syndromic hearing loss caused by likely pathogenic variants in the <i>NARS2</i> gene].","authors":"Y N Wang, H E Xu, L Mao, G S Fu, Y Xu, D J Seng, F G Han, S F Wang","doi":"10.3760/cma.j.cn115330-20240514-00278","DOIUrl":"https://doi.org/10.3760/cma.j.cn115330-20240514-00278","url":null,"abstract":"<p><p><b>Objective:</b> To investigate the pathogenic variants and function of a pedigree with syndromic hearing loss using high-throughput sequencing. <b>Methods:</b> Detailed medical history and pedigree history were inquired, and a pedigree chart was drawn. Hearing examinations were performed on this pedigree, and whole-exome sequencing and bioinformatics analysis were performed to screen for suspected pathogenic variants. Then, Sanger sequencing was used to test co-segregation in the family, and transcriptome sequencing was used to investigate the effect of a variant on splicing. <b>Results:</b> The proband has auditory neuropathy combined with symptoms such as development delay, muscle weakness, and seizure. The patient carries two variants in <i>NARS2</i> (NM_024678.6), namely: c.779A>C (p.Glu260Ala) and c.372+3A>G (intronic variant), of which c.779A>C is inherited from the father and c.372+3A>G from the mother. Both variants have not been reported in the literature or included in any databases. Transcriptome sequencing results indicate that the c.372+3A>G variant leads to the skipping of the third exon during transcription. According to the American College of Medical Genetics and Genomics(ACMG) guidelines, the c.779A>C variant and c.372+3A>G are classified as likely pathogenic. Based on the patient's phenotype and genetic testing results, the proband has been diagnosed with combined oxidative phosphorylation deficiency 24(COXPD24). <b>Conclusions:</b> The pathogenic variants in the <i>NARS2</i> gene are the underlying cause of the patient's disease. The identification of novel variants enriches the mutational spectrum of the <i>NARS2</i> gene, providing evidence for further clarification of the relationship between <i>NARS2</i> and COXPD24.</p>","PeriodicalId":23987,"journal":{"name":"Chinese journal of otorhinolaryngology head and neck surgery","volume":"59 12","pages":"1305-1312"},"PeriodicalIF":0.0,"publicationDate":"2024-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142903782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Application and research progress of 3D printing technology in skull base reconstruction surgery].","authors":"X Lu, Q Liu, H Zhang, W Hang, X Zhai, G Liu","doi":"10.3760/cma.j.cn115330-20240523-00306","DOIUrl":"https://doi.org/10.3760/cma.j.cn115330-20240523-00306","url":null,"abstract":"","PeriodicalId":23987,"journal":{"name":"Chinese journal of otorhinolaryngology head and neck surgery","volume":"59 ","pages":"1232-1236"},"PeriodicalIF":0.0,"publicationDate":"2024-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142740690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Free flap reconstruction in the naso-cranial base region].","authors":"J Cui, T F Zhao, Z Y Wang, Q T Yang, J Ye, Z H Shi","doi":"10.3760/cma.j.cn115330-20240523-00306","DOIUrl":"https://doi.org/10.3760/cma.j.cn115330-20240523-00306","url":null,"abstract":"","PeriodicalId":23987,"journal":{"name":"Chinese journal of otorhinolaryngology head and neck surgery","volume":"59 ","pages":"1221-1225"},"PeriodicalIF":0.0,"publicationDate":"2024-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142740697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Development and evaluation of the children's postoperative health-related quality of life scale for thyroid cancer].","authors":"W Pang, S C Wang, X D Li, Y W Liu, Z Li, Y H Liu, Y Z Li, X X Zhang, Q Y Liu, N Sun, Z Y Liu, X Ni","doi":"10.3760/cma.j.cn115330-20240420-00222","DOIUrl":"https://doi.org/10.3760/cma.j.cn115330-20240420-00222","url":null,"abstract":"<p><p><b>Objective:</b> To develop the children's postoperative health-related quality of life scale for thyroid cancer and to test its reliability and validity. <b>Methods:</b> The first draft of the scale was developed through literature search, focus group meetings, and a pre-survey, and 116 children (76 for testing and 40 for external validation) with thyroid cancer attending Beijing Children's Hospital of Capital Medical University were selected to answer the scale, to screen and categorize the questions and to form the final scale with multiple dimensions. <b>Results:</b> The children's postoperative health-related quality of life scale for thyroid cancer contained 5 dimensions and 29 questions. Exploratory factor analysis showed that the cumulative variance explained by the 5 factors was 64.343%. Confirmatory factor analysis showed correlations between the questions and dimensions of this scale, fair convergent validity for the scale, and good discriminant validity. The validity of the validity scale showed that there was a existing correlation between the questions and the validity scale of this scale. The item-dimension correlation coefficients showed that the questions in each dimension were well differentiated. The total Cronbach's α coefficient of the scale was 0.930, the folded half reliability was 0.843, and retest reliabilities at 2 weeks, 1 month, and 3 months after the initial test were respectively 0.936, 0.922, and 0.910. <b>Conclusion:</b> The developed children's postoperative health-related quality of life scale for thyroid cancer has good reliability and validity and can be used to assess the health-related quality of life of children after thyroid cancer surgery.</p>","PeriodicalId":23987,"journal":{"name":"Chinese journal of otorhinolaryngology head and neck surgery","volume":"59 11","pages":"1183-1192"},"PeriodicalIF":0.0,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142781292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Preliminary efficacy of individualized genioglossus advancement with 3D printing in the treatment of obstructive sleep apnea with micrognathia].","authors":"R H Chen, F Y Liang, P Han, P L Lin, X J Lin, J Y Wang, W Q Chen, X M Huang","doi":"10.3760/cma.j.cn115330-20240311-00131","DOIUrl":"https://doi.org/10.3760/cma.j.cn115330-20240311-00131","url":null,"abstract":"<p><p><b>Objective:</b> To investigate the preliminary efficacy of 3D printed individualized genioglossus advancement (GA) for the treatment of obstructive sleep apnea (OSA) in adults with micrognathia. <b>Methods:</b> The OSA patients with retropalatal and retroglossal collapses due to micrognathia underwent 3D printed individualized GA combined with Uvulopalatopharyngoplasty(UPPP) in Department of Otolaryngology, Head and Neck Surgery, Sun Yat-sen Memorial Hospital, Sun Yat-sen University. Clinical data including pre-and post-operative polysomnography (PSG), cephalometric measurements of genioglossus advancement, patient-reported symptom and surgical complications were collected. A comparison of pre-and post-operative data was conducted using paired <i>t</i>-tests. <b>Results:</b> Nineteen OSA patients with micrognathia successfully underwent 3D printed individualized GA combined with UPPP, and achieved an actual mean genioglossus advancement distance of (9.0±1.4) mm compared to the planned distance of (9.4±1.0) mm preoperatively (<i>t</i>=0.81, <i>P</i>=0.427). Among the 14 patients followed up for more than 6 months, the mean AHI reduced by 60.4% at 6 months postoperatively, with 5 cases (5/14) cured and 5 cases (5/14) showing significant improvement, resulting in an overall surgical response rate of 10/14. All patients expressed satisfaction with their postoperative facial appearance, with 13 cases perceiving an improvement in attractiveness. Two patients reported temporary genial numbness, and one patient experienced temporary mandibular occlusal asthenia. <b>Conclusion:</b> The 3D printed individualized GA combined with UPPP effectively reduces AHI in adult OSA patients with micrognathia, accompanied by a low incidence of surgical complications and high patient satisfaction regarding postoperative facial appearance.</p>","PeriodicalId":23987,"journal":{"name":"Chinese journal of otorhinolaryngology head and neck surgery","volume":"59 11","pages":"1193-1198"},"PeriodicalIF":0.0,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142781299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}