Chinese journal of otorhinolaryngology head and neck surgery最新文献

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[Clinical characteristics of 6 cases of relapsing polychondritis in children with airway involvement]. 小儿复发性多软骨炎累及气道6例临床特点分析
Chinese journal of otorhinolaryngology head and neck surgery Pub Date : 2024-11-07 DOI: 10.3760/cma.j.cn115330-20240326-00173
G X Wang, F Z Zhang, J Zhao, H B Li, Q C Duan, J Zhang, C F Li, X Ni, H Wang
{"title":"[Clinical characteristics of 6 cases of relapsing polychondritis in children with airway involvement].","authors":"G X Wang, F Z Zhang, J Zhao, H B Li, Q C Duan, J Zhang, C F Li, X Ni, H Wang","doi":"10.3760/cma.j.cn115330-20240326-00173","DOIUrl":"https://doi.org/10.3760/cma.j.cn115330-20240326-00173","url":null,"abstract":"<p><p><b>Objective:</b> To investigate the pathogenesis, clinical signs and diagnosing procedures of relapsing polychondritis(RP) in children with airway involvement. <b>Methods:</b> The medical history, clinical symptoms, physical examination, electronic laryngoscopy and imaging findings of six patients were retrospectively analyzed. The patients diagnosed as relapsing polychondritis with involving the airway from January 2018 to December 2021 were in our hospital. The clinical features of the 6 cases were summarized. <b>Results:</b> All 6 patients were male, ranging in age from 8 years 1 month to 14 years 1 month, with a median age of 12.04 years. Stridor and dyspnea were observed in all patients, with hoarseness in 2 patients and frequently nocturnal dyspnea during sleep in 2 patients. Initially, all children were diagnosed as laryngitis or laryngotracheitis, and were treated symptomatically with glucocorticoids and aerosol inhalation. Immunosuppressants and targeted therapy with biologics were given after patients diagnosed as RP. All patients were ultimately required tracheostomy. The time from the onset of airway symptoms to tracheostomy ranged from 1 month to 27 months. Two children had a history of endotracheal intubation prior to tracheostomy. All 6 patients underwent electronic laryngoscopy, revealing involvement of the laryngeal and subglottic mucosa and cartilage structures, which showed gradual improvement with medical therapy. Computed tomography (CT) of the trachea with three-dimensional reconstruction was performed in all patients, demonstrating moderate to severe subglottic stenosis. Two patients exhibited complete airway obstruction at the C4-C6 cervical level. Three children underwent suspension laryngoscopy under general anesthesia and endotracheal mucosal biopsy.Of the 6 children, 3 presented with nasal tip collapse or saddle nose, 2 had auricular cartilage changed, and 1 had scleralinvolvement. One patient underwent PET-CT scanning, which revealed tracheal collapse, diffuse increase in FDG(Flurodeoxyglucose)metabolism with increased FDG uptake in the nasal alar regions. All children were followed up for 2-3 years, 1 child died, while the remaining five continued to receive medical treatment. <b>Conclusions:</b> Relapsing polychondritis with airway involvement has an insidious onset and is difficult to diagnose. The airway stenosisresulting from RP is always severe and necessitating tracheotomy to maintain airway patency in the majority of cases.The treatment coursef or RP is prolonged, requiring long-term tracheostomy tube placement.</p>","PeriodicalId":23987,"journal":{"name":"Chinese journal of otorhinolaryngology head and neck surgery","volume":"59 11","pages":"1210-1215"},"PeriodicalIF":0.0,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142781284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Selection of tracheostomy for total laryngectomy]. 全喉切除术气管造口术的选择。
Chinese journal of otorhinolaryngology head and neck surgery Pub Date : 2024-11-07 DOI: 10.3760/cma.j.cn115330-20240628-00380
Y X Lu, D X Nong
{"title":"[Selection of tracheostomy for total laryngectomy].","authors":"Y X Lu, D X Nong","doi":"10.3760/cma.j.cn115330-20240628-00380","DOIUrl":"10.3760/cma.j.cn115330-20240628-00380","url":null,"abstract":"","PeriodicalId":23987,"journal":{"name":"Chinese journal of otorhinolaryngology head and neck surgery","volume":"59 11","pages":"1249-1253"},"PeriodicalIF":0.0,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142781303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Applications of vascularized pericranial flaps in endoscopic skull base surgeries]. [血管化颅骨周围皮瓣在内窥镜颅底手术中的应用]。
Chinese journal of otorhinolaryngology head and neck surgery Pub Date : 2024-11-07 DOI: 10.3760/cma.j.cn115330-20240319-00148
R Tang, S Mao, Y L Gu, Z P Li, W T Zhang
{"title":"[Applications of vascularized pericranial flaps in endoscopic skull base surgeries].","authors":"R Tang, S Mao, Y L Gu, Z P Li, W T Zhang","doi":"10.3760/cma.j.cn115330-20240319-00148","DOIUrl":"10.3760/cma.j.cn115330-20240319-00148","url":null,"abstract":"<p><p><b>Objective:</b> To study the feasibility and efficacy of pericranial flaps for the repairs of large anterior skull base defects. <b>Methods:</b> The average length of the pericranial flaps needed for skull base repair was determined with computed tomography measurements in 20 adults and anatomical dissections in 5 cadaver specimen. A series of patients who underwent endoscopic skull base surgeries and subsequent reconstructions with pericranial flaps at the Department of Otolaryngology Head and Neck Surgery, Shanghai Jiao Tong University School of Medicine Affiliated Sixth People's Hospital from 2016 to 2022 were retrospectively reviewed. There were 19 males and 6 females, aged from 11 to 59 years, including 13 cases of cerebrospinal fluid (CSF) rhinorrhea (12 traumatic) and 12 cases of sinonasal skull base tumors. Descriptive statistical methods were used. <b>Results:</b> The mean areas of anterior skull base, sellar, and clival defects were 16.13, 14.03 and 13.12 cm<sup>2</sup>, respectively, and the mean pericranial flap lengths were (18.77±3.44)mm, (133.99±5.08)mm, (181.76±6.31)mm, respectively. Among sinonasal skull base neoplasms, the pathologies included olfactory neuroblastoma (<i>n</i>=6), squamous cell carcinoma (<i>n</i>=3), chondrosarcoma (<i>n</i>=1), osteosarcoma (<i>n</i>=1), and invasive schwannoma (<i>n</i>=1), in whom 8 patients underwent adjuvant radiotherapy after surgery. One patient (7.7%) had acoustic neuroma-related CSF leak before radiotherapy. All 25 patients successfully underwent skull base reconstruction without complications such as CSF leak, intracranial infection, forehead wrinkles disappearance, or scalp necrosis. All flaps survived well with no CSF leaks within the follow-up period of 2-4 years. <b>Conclusion:</b> Pericranial flap is a safe choice for large anterior skull base defects following resection of sinonasal skull base neoplasms and complex traumatic CSF leaks when endonasal flaps are not available.</p>","PeriodicalId":23987,"journal":{"name":"Chinese journal of otorhinolaryngology head and neck surgery","volume":"59 ","pages":"1199-1204"},"PeriodicalIF":0.0,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142740692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Clinical practice guidelines for children's hearing aid fitting(2024)]. [中国儿童助听器验配临床实践指南]。
Chinese journal of otorhinolaryngology head and neck surgery Pub Date : 2024-11-07 DOI: 10.3760/cma.j.cn115330-20240604-00332
{"title":"[Clinical practice guidelines for children's hearing aid fitting(2024)].","authors":"","doi":"10.3760/cma.j.cn115330-20240604-00332","DOIUrl":"10.3760/cma.j.cn115330-20240604-00332","url":null,"abstract":"","PeriodicalId":23987,"journal":{"name":"Chinese journal of otorhinolaryngology head and neck surgery","volume":"59 ","pages":"1126-1135"},"PeriodicalIF":0.0,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142740694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Position paper on diagnosis and treatment of type 2 chronic rhinosinusitis]. [关于 2 型慢性鼻炎诊断和治疗的立场文件]。
Chinese journal of otorhinolaryngology head and neck surgery Pub Date : 2024-10-07 DOI: 10.3760/cma.j.cn115330-20240518-00289
J B Shi, L Cheng, H B Li, Z Liu, C S Wang, Y Q Sun, H Y Hong, Q T Yang, K J Zuo, R Xu, P P Cao, Y Y Lai, F H Chen, Y N Zhang, G Xu, L Zhang
{"title":"[Position paper on diagnosis and treatment of type 2 chronic rhinosinusitis].","authors":"J B Shi, L Cheng, H B Li, Z Liu, C S Wang, Y Q Sun, H Y Hong, Q T Yang, K J Zuo, R Xu, P P Cao, Y Y Lai, F H Chen, Y N Zhang, G Xu, L Zhang","doi":"10.3760/cma.j.cn115330-20240518-00289","DOIUrl":"https://doi.org/10.3760/cma.j.cn115330-20240518-00289","url":null,"abstract":"","PeriodicalId":23987,"journal":{"name":"Chinese journal of otorhinolaryngology head and neck surgery","volume":"59 10","pages":"990-1001"},"PeriodicalIF":0.0,"publicationDate":"2024-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142547955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Review of the development and latest perspectives in 2024 on Allergic Rhinitis and its Impact on Asthma (ARIA)]. [过敏性鼻炎及其对哮喘的影响(ARIA)的发展回顾和 2024 年的最新展望]。
Chinese journal of otorhinolaryngology head and neck surgery Pub Date : 2024-10-07 DOI: 10.3760/cma.j.cn115330-20240725-00450
X Luo, Z X Hua, Y N Zhang, Q T Yang
{"title":"[Review of the development and latest perspectives in 2024 on Allergic Rhinitis and its Impact on Asthma (ARIA)].","authors":"X Luo, Z X Hua, Y N Zhang, Q T Yang","doi":"10.3760/cma.j.cn115330-20240725-00450","DOIUrl":"https://doi.org/10.3760/cma.j.cn115330-20240725-00450","url":null,"abstract":"","PeriodicalId":23987,"journal":{"name":"Chinese journal of otorhinolaryngology head and neck surgery","volume":"59 10","pages":"1107-1114"},"PeriodicalIF":0.0,"publicationDate":"2024-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142547957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Analysis of 15 children with type Ⅳ branchial cleft cyst treated with endoscopic transoral approach]. [采用内窥镜经口方法治疗 15 名Ⅳ型腮裂囊肿患儿的分析]。
Chinese journal of otorhinolaryngology head and neck surgery Pub Date : 2024-10-07 DOI: 10.3760/cma.j.cn115330-20240606-00339
Q C Duan, F Z Zhang, G X Wang, D J Seng, H B Ren, E L Qian, J Zhang
{"title":"[Analysis of 15 children with type Ⅳ branchial cleft cyst treated with endoscopic transoral approach].","authors":"Q C Duan, F Z Zhang, G X Wang, D J Seng, H B Ren, E L Qian, J Zhang","doi":"10.3760/cma.j.cn115330-20240606-00339","DOIUrl":"10.3760/cma.j.cn115330-20240606-00339","url":null,"abstract":"<p><p><b>Objective:</b> To analyze the clinical characteristics and endoscopic surgical procedures of the second branchial cleft cyst type Ⅳ in children. <b>Methods:</b> A retrospective review was conducted on 15 pediatric cases with type Ⅳ second branchial cleft cysts treated at the Beijing Children's Hospital affiliated with Capital Medical University and Henan Children's Hospital from September 2019 to November 2023. All patients underwent excision via a two-person, three-hand endoscopic transoral approach. The cohort included 12 males and 3 females, with an age range of 10 months to 10 years and 5 months, and a median age of (59.20±32.05) months. The clinical data of initial symptoms, sides, imaging features, treatment methods, complications, length of hospital stay, prognosis and outcome were recorded and analyzed. SPSS 22.0 software was used for statistical analysis. <b>Results:</b> Of the 15 children, 13 cases presented with snoring as the primary symptom, 1 case with dysphagia, and 1 case was asymptomatic and was found unintentionally. The mean disease duration was (6.74±9.05) months (range, from 3 days-2 years). MRI revealed cystic lesions on the right side in 12 cases and on the left side in 3 cases, characterized by uniform long T2 signal, equal T1 or short T1 signal. The cysts appeared dumbbell-shaped in 10 cases with the pharyngeal constrictor muscle as the waist, the posterior outside of the mass was adjacent to the internal carotid artery. The remaining 5 cases showed an isolated cyst located inside the pharyngeal constrictor muscle. The intraoperative MRI findings were consistent. Partial cystectomy was performed in 10 cases near the internal carotid artery, leaving only the portion with a clear arterial pulse intact. Five cases with isolated cysts on the medial side of the pharyngeal constrictor muscle were totally removed. The average length of hospital stay was (4.53±0.52) days (4-5 days). All patients were followed up for 7-56 months [median (30±15.12) months] with no recurrence of symptoms observed. <b>Conclusions:</b> The second branchial cleft cyst type Ⅳ in children is characterized by prominent pharyngeal cystic mass, with snoring as a predominant initial symptom, MRI provides excellent diagnostic value. The two-person, third-hand endoscopic transoral approach for cyst excision is feasible, safe, and offers the benefits of minimal invasiveness and reduced hospitalization time.</p>","PeriodicalId":23987,"journal":{"name":"Chinese journal of otorhinolaryngology head and neck surgery","volume":"59 ","pages":"1042-1047"},"PeriodicalIF":0.0,"publicationDate":"2024-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142509343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Application of mitoxantrone hydrochloride in lymph node imaging during radical thyroidectomy]. [盐酸米托蒽醌在甲状腺根治术淋巴结成像中的应用]。
Chinese journal of otorhinolaryngology head and neck surgery Pub Date : 2024-10-07 DOI: 10.3760/cma.j.cn115330-20240518-00287
Y Cheng, S Zhang, Z W Liu, L L Liu, Y Wang, J H Gu
{"title":"[Application of mitoxantrone hydrochloride in lymph node imaging during radical thyroidectomy].","authors":"Y Cheng, S Zhang, Z W Liu, L L Liu, Y Wang, J H Gu","doi":"10.3760/cma.j.cn115330-20240518-00287","DOIUrl":"10.3760/cma.j.cn115330-20240518-00287","url":null,"abstract":"&lt;p&gt;&lt;p&gt;&lt;b&gt;Objective:&lt;/b&gt; To investigate the clinical application value of the new tracer mitoxantrone hydrochloride in imaging of cervical lymph nodes and identifying of parathyroid, recurrent laryngeal nerve during thyroid cancer radical surgery. &lt;b&gt;Methods:&lt;/b&gt; A prospective controlled study was conducted between January 2022 and April 2024 at Tianjin First Central Hospital, recruiting 180 patients with thyroid cancer, including 54 males and 126 females, aged from 26 to 69 years. The patients were randomly divided into three groups: the mitoxantrone hydrochloride lymph node tracing group (MHI group), the nanocarbon lymph node tracing group (nanocarbon group), and the control group without lymph node tracers, with 60 cases in each group. All patients underwent total thyroid resection and regional lymph node dissection. The number of detected lymph nodes and positive metastatic lymph nodes and surgical field clarity scores and the identification rate of parathyroid glands and the instances of inadvertent excision were compared between the groups. Serum calcium and parathyroid hormone (PTH) levels at different perioperative time points and treatment-related complications were analyzed. One-way ANOVA, chi-square test and two independent sample non-parametric tests, were employed for statistical analyses. &lt;b&gt;Results:&lt;/b&gt; The mean operation time, neck drainage volume and hospital stay in the MHI group and the nanocarbon group were respectively significantly lower than those in the control group (&lt;i&gt;P&lt;/i&gt;&lt;0.05). The mean staining intensity score, tracer success rate and surgical field clarity score in MHI group were respectively significantly higher than those in nanocarbon group (&lt;i&gt;P&lt;/i&gt;&lt;0.05). The mean numbers of dissected lymph nodes positive metastatic nodes and identification rates of parathyroid glands in MHI group were respectively significantly higher than those in both the nanocarbon and control groups (&lt;i&gt;P&lt;/i&gt;&lt;0.05). The rates of inadvertent parathyroid excision in both MHI group and nanocarbon group were significantly lower than those in control group (&lt;i&gt;P&lt;/i&gt;&lt;0.05). On postoperative day 1 and day 5, mean serum calcium and PTH levels in MHI group were respectively significantly higher than those in nanocarbon group and control groups. However, on postoperative day 1, there was no difference in mean serum calcium levels between the nanocarbon group and the control group (&lt;i&gt;P&lt;/i&gt;&gt;0.05), though PTH level in the nanocarbon group was higher than that in the control group. By postoperative day 5, both serum calcium and PTH levels were higher in the nanocarbon group compared to the control group (&lt;i&gt;P&lt;/i&gt;&lt;0.05). On postoperative days 30, there were no differences in serum calcium and PTH levels between the MHI group and the nanocarbon group (&lt;i&gt;P&lt;/i&gt;&gt;0.05). The risks of facial numbness, hand and foot tetany and choking during drinking were lower in both the MHI and nanocarbon groups compared to the control group (&lt;i&gt;P&lt;/i&gt;&lt;0.05). &lt;b&gt;Conclusion:&lt;","PeriodicalId":23987,"journal":{"name":"Chinese journal of otorhinolaryngology head and neck surgery","volume":"59 10","pages":"1064-1071"},"PeriodicalIF":0.0,"publicationDate":"2024-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142547948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Giant cell tumor of the hyoid bone: a case report]. [舌骨巨细胞瘤:病例报告]。
Chinese journal of otorhinolaryngology head and neck surgery Pub Date : 2024-10-07 DOI: 10.3760/cma.j.cn115330-20240601-00330
J B Zhao, W T Wei, T Wang
{"title":"[Giant cell tumor of the hyoid bone: a case report].","authors":"J B Zhao, W T Wei, T Wang","doi":"10.3760/cma.j.cn115330-20240601-00330","DOIUrl":"10.3760/cma.j.cn115330-20240601-00330","url":null,"abstract":"","PeriodicalId":23987,"journal":{"name":"Chinese journal of otorhinolaryngology head and neck surgery","volume":"59 10","pages":"1085-1087"},"PeriodicalIF":0.0,"publicationDate":"2024-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142547953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Analysis of long-term efficacy of CO2 laser partial excision of vocal folds for 599 cases in the treatment of vocal cord leukoplakia]. [599 例声带白斑病患者接受二氧化碳激光声带部分切除术的长期疗效分析]。
Chinese journal of otorhinolaryngology head and neck surgery Pub Date : 2024-10-07 DOI: 10.3760/cma.j.cn115330-20240720-00432
H Z Wang, X Y Liu, X Y Li, L Y Cheng, R Hu, Q W Yang, Y R Li, W Xu
{"title":"[Analysis of long-term efficacy of CO<sub>2</sub> laser partial excision of vocal folds for 599 cases in the treatment of vocal cord leukoplakia].","authors":"H Z Wang, X Y Liu, X Y Li, L Y Cheng, R Hu, Q W Yang, Y R Li, W Xu","doi":"10.3760/cma.j.cn115330-20240720-00432","DOIUrl":"10.3760/cma.j.cn115330-20240720-00432","url":null,"abstract":"&lt;p&gt;&lt;p&gt;&lt;b&gt;Objective:&lt;/b&gt; To analyze long-term prognosis and influencing factors of recurrence in vocal fold leukoplakia treated by endoscopic cordectomy with CO&lt;sub&gt;2&lt;/sub&gt; laser. &lt;b&gt;Methods:&lt;/b&gt; A retrospective review was conducted on 599 patients with vocal fold leukoplakia [566 males and 33 females, aged 17-84 years (median age 55 years)], undergoing endoscopic cordectomy by CO&lt;sub&gt;2&lt;/sub&gt; laser under general anesthesia at the Department of Otorhinolaryngology Head and Neck Surgery of Beijing Tongren Hospital, Capital Medical University, from January 2000 to December 2023. The study analyzed the clinical features, pathological grade, surgical methods, postoperative voice function, recurrence, malignant changes and analyzed the long-term efficacy and and its influencing factors. The patients were followed up for a duration of 6-249 months postoperatively, with a median follow-up time of 48 months. SPSS 20.0 software was used for statistical analysis. &lt;b&gt;Results:&lt;/b&gt; Among the 599 patients, the histopathological grades included simple squamous cell hyperplasia in (&lt;i&gt;n&lt;/i&gt;=264, 44.08%), mild dysplasia (&lt;i&gt;n&lt;/i&gt;=96, 16.03%), moderate dysplasia (&lt;i&gt;n&lt;/i&gt;=74, 12.35%), severe dysplasia(&lt;i&gt;n&lt;/i&gt;=43, 7.81%), carcinoma in situ(&lt;i&gt;n&lt;/i&gt;=35, 5.84%), and carcinoma in situ with microinvasion(&lt;i&gt;n&lt;/i&gt;=87, 14.52%). The 3-year and 5-year overall recurrence rates were 12.91% and 16.00%, respectively. In patients with precancerous lesion, 3.91% of recurrences presented with an upgraded pathologic grade and 2.34% evolved into carcinoma. The risk of recurrence was higher in lesions involving the anterior commissure, larger lesions, significant reduction/absence of mucosal waves, neovascularization/suspected neovascularization, and pathology of dysplasia/carcinoma in situ/carcinoma in situ with microinvasion(&lt;i&gt;F&lt;/i&gt;=44.76,21.54,11.55,8.78,23.20,respectively,&lt;i&gt;P&lt;&lt;/i&gt;0.05). Additionally, patients with recurrent disease exhibited higher reflux symptom index scores compared to those without recurrence. Exophytic lesion characteristics and the inability to cease smoking postoperatively were identified as independent risk factors for recurrence with an upgraded pathological grade, with odds ratios of 8.675 and 11.380 times greater than those with non-exophytic lesions and successful smoking cessation, respectively. At the 6-months postoperative assessment, patients who underwent subepithelial cordectomy (typeⅠ) demonstrated a statistically significant increase in fundamental frequency (&lt;i&gt;t&lt;/i&gt;=-3.38, &lt;i&gt;P&lt;/i&gt;&lt;0.05), and while other voice acoustic parameters were not significantly different.Conversely, those who underwent transmuscular cordectomy (TypeⅢ) exhibited significant alterations in multiple voice acoustic parameters when compared to preoperative values (&lt;i&gt;P&lt;/i&gt;&lt;0.05). Furthermore, postoperative vocal fold adhesions developed in 84 patients with 13 of these individuals requiring surgical intervention for adhesion release. &lt;b&gt;Conclusions:&lt;/b&gt; Lesions involving ","PeriodicalId":23987,"journal":{"name":"Chinese journal of otorhinolaryngology head and neck surgery","volume":"59 ","pages":"1029-1036"},"PeriodicalIF":0.0,"publicationDate":"2024-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142509344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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