{"title":"[Experimental studies on immunostimulatory effects of the Isatis indigotica polysaccharide].","authors":"Y M Xu, P C Lu","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Polysaccharides extracted from the root of Isatis indigotica (IIP, 50 mg/kg.d, ipx8d) significantly increased the weight of spleen and number of white blood cell and lymphocyte in peripheral blood in normal ICR mice, and antagonized the immunosuppressive actions of hydrocortisone. There were marked potentiating effects on delayed hypersensitivity reaction induced by 2, 4-dinitrochlorobenzene in normal NIH mice treated with IIP as well as in immunodepressed mice induced by cyclophosphamide. By administration of IIP, the percentage of ANAE+ lymphocytes stained with acid alpha-naphthyl acetate esterase method were significantly increased in peripheral blood of normal ICR mice, and the decreases in number of ANAE+ lymphocytes in mice induced by hydrocortisone were prevented to a certain extent. But IIP could not enhance Con A-induced lymphocyte proliferation of C57BL mouse spleen cells in vitro measured with MTT colorimetric assay. In addition, the plaque forming cells in 5 x 10(6) splenocytes of NIH mice treated with IIP were higher than that of the control group (P less than 0.01). IIP could also elevate the clearance rate of intra-venous charcoal particles in normal mice, i.e., stimulated the phagocytic activity of macrophages. The result indicates that IIP is capable of increasing humoral and cellular immune functions and enhancing the functions of reticuloendothelial system, and might be a good immunopotentiator.</p>","PeriodicalId":23984,"journal":{"name":"Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine","volume":"11 6","pages":"357-9, 325-6"},"PeriodicalIF":0.0,"publicationDate":"1991-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13049787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Treatment of idiopathic thrombocytopenic purpura with Chinese herbal drugs].","authors":"Y C Li","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":23984,"journal":{"name":"Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine","volume":"11 6","pages":"380-1"},"PeriodicalIF":0.0,"publicationDate":"1991-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13050364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Protective effect of Angelica injection on arrhythmia during myocardial ischemia reperfusion in rat].","authors":"X X Zhuang","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The protective effects of Angelica injection on arrhythmia were studied through the model of ischemic myocardial reperfusion in rats. The results showed that the incidence of ventricular premature beat and the total incidence of arrhythmia (IA) were greatly reduced by peritoneal injection of Angelica (0.6 gm crude drug/kg) in rats. The difference between the Angelica group (n = 12, IA = 41.7%) and the saline control group (n = 12, IA = 91.7%) was significant (P less than 0.05), while that between Angelica group and verapamil group (n = 10, IA = 40%) was insignificant (P greater than 0.05). The data suggested that Angelica injection is effective on the protection of arrhythmia during the myocardial ischemia reperfusion in rats.</p>","PeriodicalId":23984,"journal":{"name":"Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine","volume":"11 6","pages":"360-1, 326"},"PeriodicalIF":0.0,"publicationDate":"1991-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13050362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Long-term changes in the different types of coronary diseases treated with traditional Chinese and Western medicine].","authors":"J Bao, J G Lou","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>64 cases with TCM differential types of CHD treated with TCM-WM in long term (an average of 10.5 years) were divided into four types according to deficiency of Yang [including weakness of Q1], deficiency of Yin, blood stasis and disorder of Qi and phlegm. Compared with pre-treatment 42 cases (65.62%) with TCM differential types showed improvement or no change in group I, II (clinical total effective rate 92.86%, the significantly effective rate 40.98%). While 22 cases (34.38%) with TCM differential type became aggravated or worse (clinical total effective rate 54.54%, the significantly effective rate 13.63%). The report indicated that the results in comparing group I, II with group III, IV were statistically significant; age (P less than 0.01), course of disease (P less than 0.01), impairment of myocardium (P less than 0.05), complication (P less than 0.05), ratio of deficiency of Yang (P less than 0.01), blood stasis (P less than 0.01) and high coagulation of blood (P less than 0.01). Therefore the author suggests that it is necessary to protect Yang-Qi and prevent and treat the complication of the CHD patients.</p>","PeriodicalId":23984,"journal":{"name":"Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine","volume":"11 5","pages":"277-9, 261"},"PeriodicalIF":0.0,"publicationDate":"1991-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13038900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Primary research on the clinical significance of ventricular late potentials (VLPs), and the impact of mexiletine, lidocaine and Astragalus membranaceus on VLPs].","authors":"H M Shi, R H Dai, S Y Wang","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The body surface signal-averaged electrocardiogram (SAECG) was recorded on 316 cardiac patients, 84% (266 patients) of whom were also taken 24-hour Holter ECG. VLPs were detected positively in 6.1%, 25%, 25.7%, 14.3% and 5.5% of patients with angina pectoris, myocardial infarction, myocarditis, cardiomyopathy and arrhythmia of unknown origin respectively, and the patients with complex ventricular arrhythmia had more VLPs positive determination definitely (P less than 0.05). The specificity of VLPs in the prediction of complex ventricular arrhythmia was greater than 80%, and the positive predictive accuracy was 70-80%. 5, 5 and 10 patients with VLPs were treated with Mexiletini Hydrochloridum, Lidocaini Hydrochloridum and Injection of Astragalus membranaceus respectively. As a result of treatment, the transfer of VLPs positive to negative was unsuccessful, but only the intervention of Astragalus membranaceus Injection made the duration of VLPs shortened significantly (39.8 +/- 3.3 ms versus 44.5 +/- 5.9 ms, P less than 0.01).</p>","PeriodicalId":23984,"journal":{"name":"Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine","volume":"11 5","pages":"265-7, 259"},"PeriodicalIF":0.0,"publicationDate":"1991-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13039013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Effect of eleutherosides on ventricular late potential with coronary heart disease and myocarditis].","authors":"S Y Shang, Y S Ma, S S Wang","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The article studied the curative effect of eleutherosides in patients with coronary heart disease and myocarditis whose ventricular late potential (VLP) were positive by means of control study. All the 57 patients were randomly divided into two groups. The 31 patients were classified as therapeutic group including male 25 and female 6, the ages ranged from 18-65 years old (mean 51.8). The other 26 patients were defined as control group including male 21 and female 5, the ages ranged from 16-63 years old (mean 50.8). The therapeutic group was treated with injectio acanthopanacis senticosi 40 ml dissolved in 5% dextrose injection 300 ml by intravenous drop once daily. The control group was given insulin injection 12 u and potassium chloride injection 1 g dissolved in 10% dextrose injection 500 ml also by intravenous drop once daily. Both courses of treatment were 15 days. The rates of changing positive VLP into negative in two groups were 74.29% vs 34.6% (P less than 0.005). The results proved that eleutherosides is an effective drug to patients with positive VLP.</p>","PeriodicalId":23984,"journal":{"name":"Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine","volume":"11 5","pages":"280-1, 261"},"PeriodicalIF":0.0,"publicationDate":"1991-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13038901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Advance in drug treatment of primary and familial hypercholesterolemia].","authors":"K Liu","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":23984,"journal":{"name":"Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine","volume":"11 5","pages":"315-7"},"PeriodicalIF":0.0,"publicationDate":"1991-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13038907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Relation between traditional Chinese medicine differential types and plasma levels of renin, angiotension II, aldosterone, atrial natriuretic factor in patients with essential hypertension].","authors":"H Li","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>130 cases of patients with essential hypertension (EH) and 70 cases of normal subjects were researched for correlation between TCM differential types and plasma levels of renin, angiotension II, aldosterone, atrial natriuretic factor (ANF) in patients with EH. Results indicated that: (1) basic level of renin was lower in patients with EH than that in normal subject. There were significant differences of plasma levels of renin between different TCM types. Plasma renin level of excessive Yang patients was higher than that in normal subject group and groups of deficiency of Yin essence combined with excessive Yang as well as deficiency of both Yin and Yang (P less than 0.01-0.001). Plasma level of angiotension II was significantly higher in group of excessive Yang than that in normal subject and other two groups (P less than 0.01-0.001). It was indicated that there were correlation between plasma basic level of renin, angiotension II and TCM types. (2) Plasma ANF level in patients with EH was significantly lower than that in group of normal subject (P less than 0.01). There were significant differences between groups of three different TCM types (P greater than 0.05). The result suggested that lower plasma ANF level was general character in three groups with EH. The prognosis of these patients was discussed.</p>","PeriodicalId":23984,"journal":{"name":"Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine","volume":"11 5","pages":"271-3, 260"},"PeriodicalIF":0.0,"publicationDate":"1991-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12993213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Experimental and clinical study of tong jing bao and Angelicae complex injection in treating fallopian tube obstruction].","authors":"F Lian, N Q Sun, G C Xia","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Twenty-two female rabbits with fallopian tube obstruction as the model, were made by 25% Phenol-Tragacanth Mucilage in the laboratory study. Eight rabbits were treated by taking Tong Jing Bao and giving transcervical intrauterine injecting of Angelicae complex injection. Seven were treated with the latter and other seven with 0.9% saline only as the control group. The study showed that in the opening fallopian tube, anti-inflammation, limiting the hyperplasia of fibro-connective tissue and improving the regeneration of epithelial tissue, the first group was more effective than the other two groups (P less than 0.05). Forty-eight infertile women, in whom the fallopian tube obstruction were proved by hysterosalpingography, were divided into two groups for the clinical study. Thirty patients were treated as same as the first group of rabbits. As the control group, other eighteen women were treated with transcervical intrauterine injecting of gentamycin and 0.9% saline in 3 to 6 months. The effective rates were 94.6% and 56.6% (P less than 0.01) and the subsequent pregnancy rates were 46.7% and 27.8% respectively in the different two groups.</p>","PeriodicalId":23984,"journal":{"name":"Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine","volume":"11 5","pages":"282-5, 262"},"PeriodicalIF":0.0,"publicationDate":"1991-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13038902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Protective effect of sheng mai injection on myocardial injury induced by adriamycin in cultured myocardial cells].","authors":"Q Cai","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The effect of sheng mai injection (SMI) on adriamycin-induced cardiotoxicity in cultured myocardial cells was examined. Adriamycin treatment (1 mg/L) for 4 h of culture age, increased remarkably the leakage of lactate dehydrogenase (LDH) from the myocardial cells, and induced the damage of ultrastructure. SMI (30 mg/L, 100 mg/L, 300 mg/L) had no effects on these changes induced by adriamycin. The results showed that SMI had no direct protective effect on adriamycin cardiotoxicity in cultured myocardial cells. It's protective effect on adriamycin cardiotoxicity seems to be in whole body level, the mechanism of which was relating to the metabolism of the drug in organism, and is worthy of further research.</p>","PeriodicalId":23984,"journal":{"name":"Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine","volume":"11 5","pages":"286-8, 262"},"PeriodicalIF":0.0,"publicationDate":"1991-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13038903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}