【当归注射液对大鼠心肌缺血再灌注心律失常的保护作用】。

Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine Pub Date : 1991-06-01

X X Zhuang

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引用次数: 0

摘要

通过大鼠缺血心肌再灌注模型，研究当归注射液对心律失常的保护作用。结果表明，腹腔注射当归(0.6 gm生药/kg)可显著降低大鼠室性早搏发生率和心律失常总发生率。当归组(n = 12, IA = 41.7%)与生理盐水对照组(n = 12, IA = 91.7%)比较差异有统计学意义(P < 0.05)，而当归组与维拉帕米组(n = 10, IA = 40%)比较差异无统计学意义(P > 0.05)。提示当归注射液对大鼠心肌缺血再灌注时心律失常有保护作用。

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[Protective effect of Angelica injection on arrhythmia during myocardial ischemia reperfusion in rat].

The protective effects of Angelica injection on arrhythmia were studied through the model of ischemic myocardial reperfusion in rats. The results showed that the incidence of ventricular premature beat and the total incidence of arrhythmia (IA) were greatly reduced by peritoneal injection of Angelica (0.6 gm crude drug/kg) in rats. The difference between the Angelica group (n = 12, IA = 41.7%) and the saline control group (n = 12, IA = 91.7%) was significant (P less than 0.05), while that between Angelica group and verapamil group (n = 10, IA = 40%) was insignificant (P greater than 0.05). The data suggested that Angelica injection is effective on the protection of arrhythmia during the myocardial ischemia reperfusion in rats.

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Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine

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