中国修复重建外科杂志最新文献

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[Research progress in etiology and prevention of bone cement implantation syndrome].
中国修复重建外科杂志 Pub Date : 2025-02-15 DOI: 10.7507/1002-1892.202410068
Guangtao Han, Qin Wang, Shuo Sun, Pengde Kang
{"title":"[Research progress in etiology and prevention of bone cement implantation syndrome].","authors":"Guangtao Han, Qin Wang, Shuo Sun, Pengde Kang","doi":"10.7507/1002-1892.202410068","DOIUrl":"10.7507/1002-1892.202410068","url":null,"abstract":"<p><strong>Objective: </strong>To introduce the etiology and prevention of bone cement implantation syndrome (BCIS).</p><p><strong>Methods: </strong>The literature about BCIS at home and abroad in recent years was extensively reviewed, and the incidence, clinical manifestations, etiology, and prevention of BCIS were summarized and analyzed.</p><p><strong>Results: </strong>The clinical manifestations of BCIS are diverse. The etiology of BCIS is not completely clarified, and it may be related to circulating methyl methacrylate-mediated model, embolus-mediated model, histamine release and hypersensitivity response, complement activation and multimodal model. BCIS prevention begins with the identification of high-risk patients in preoperative evaluation and communication between surgeon and anesthesiologist about the choice of implant type, surgical procedure, and technique to minimize the risk of cardiovascular complications in high-risk patients with multiple or severe risk factors or comorbidities. Preoperative assessment and optimization of a patient's cardiovascular reserve is also critical to prevent BCIS.</p><p><strong>Conclusion: </strong>BCIS is a possible complication after hip joint arthroplasty, and its pathogenesis needs to be further research in order to provide new ideas for prevention and treatment.</p>","PeriodicalId":23979,"journal":{"name":"中国修复重建外科杂志","volume":"39 2","pages":"237-242"},"PeriodicalIF":0.0,"publicationDate":"2025-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11839285/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143459782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Effectiveness of digital three-dimensional printing osteotomy guide plate assisted total knee arthroplasty in treatment of knee osteoarthritis patients with femoral internal implant].
中国修复重建外科杂志 Pub Date : 2025-02-15 DOI: 10.7507/1002-1892.202411104
Chao Li, Binbin Zhang, Xiangping Liu, Haiya Li, Jingtang Zhang, Min Wu
{"title":"[Effectiveness of digital three-dimensional printing osteotomy guide plate assisted total knee arthroplasty in treatment of knee osteoarthritis patients with femoral internal implant].","authors":"Chao Li, Binbin Zhang, Xiangping Liu, Haiya Li, Jingtang Zhang, Min Wu","doi":"10.7507/1002-1892.202411104","DOIUrl":"10.7507/1002-1892.202411104","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;To investigate the effectiveness of digital three-dimensional (3D) printing osteotomy guide plate assisted total knee arthroplasty (TKA) in treatment of knee osteoarthritis (KOA) patients with femoral internal implants.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;The clinical data of 55 KOA patients who met the selection criteria between July 2021 and October 2023 were retrospectively analyzed. Among them, 26 cases combined with femoral implants were treated with digital 3D printing osteotomy guide plate assisted TKA (guide plate group), and 29 cases were treated with conventional TKA (control group). There was no significant difference in gender, age, body mass index, side, Kellgren-Lawrence classification, preoperative visual analogue scale (VAS) score, Hospital for Special Surgery (HSS) knee score, knee range of motion, and other baseline data between the two groups ( &lt;i&gt;P&lt;/i&gt;&gt;0.05). The operation time, intraoperative blood loss, incision length, postoperative first ambulation time, surgical complications; VAS score, knee HSS score, knee range of motion before operation, at 1 week and 3 months after operation, and at last follow-up; distal femoral lateral angle, proximal tibial medial angle, hip-knee-ankle angle and other imaging indicators at last follow-up were recorded and compared between the two groups.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;The operation time, incision length, intraoperative blood loss, and postoperative first ambulation time in the guide plate group were significantly lower than those in the control group ( &lt;i&gt;P&lt;/i&gt;&lt;0.05). In the control group, there were 1 case of incision rupture and bleeding and 1 case of lower limb intermuscular venous thrombosis, which was cured after symptomatic treatment. There was no complication such as neurovascular injury, incision infection, or knee prosthesis loosening in both groups. Patients in both groups were followed up 12-26 months, with an average of 16.25 months. The VAS score, HSS score, and knee range of motion improved at each time point after operation in both groups, and further improved with time after operation, the differences were significant ( &lt;i&gt;P&lt;/i&gt;&lt;0.05). The above indicators in the guide plate group were significantly better than those in the control group at 1 week and 3 months after operation ( &lt;i&gt;P&lt;/i&gt;&lt;0.05), and there was no significant difference between the two groups at last follow-up ( &lt;i&gt;P&lt;/i&gt;&gt;0.05). At last follow-up, the distal femoral lateral angle, the proximal tibial medial angle, and the hip-knee-ankle angle in the guide plate group were significantly better than those in the control group ( &lt;i&gt;P&lt;/i&gt;&lt;0.05).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;The application of digital 3D printing osteotomy guide plate assisted TKA in the treatment of KOA patients with femoral implants can simplify the surgical procedures, overcome limitations of conventional osteotomy guides, reduce surgical trauma, achieve individualized and precise osteotomy, and effective","PeriodicalId":23979,"journal":{"name":"中国修复重建外科杂志","volume":"39 2","pages":"151-157"},"PeriodicalIF":0.0,"publicationDate":"2025-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11839290/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143459716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Reconstruction of phonatory function using a tubular free flap from upper-lateral upper arm after near-total laryngectomy].
中国修复重建外科杂志 Pub Date : 2025-02-15 DOI: 10.7507/1002-1892.202411048
Liu Yang, Yitao Zheng, Wen Li
{"title":"[Reconstruction of phonatory function using a tubular free flap from upper-lateral upper arm after near-total laryngectomy].","authors":"Liu Yang, Yitao Zheng, Wen Li","doi":"10.7507/1002-1892.202411048","DOIUrl":"10.7507/1002-1892.202411048","url":null,"abstract":"<p><strong>Objective: </strong>To explore the feasibility of reconstruction of phonatory function by using a tubular free flap from upper-lateral upper arm to repair the laryngotracheal circumferential defect after near-total laryngectomy for laryngeal cancer.</p><p><strong>Methods: </strong>A retrospective study was conducted on 7 patients who underwent near-total laryngectomy between June 2021 and October 2023, aged from 48 to 70 years (median, 59 years), 6 males and 1 female. The disease duration ranged from 1 to 11 months, with a median of 6 months. Pathological diagnosis of preoperative biopsy was squamous cell carcinoma. Tumor classification: glottic type in 5 cases, supraglottic type in 1 case, transglottic type in 1 case; TNM staging: T <sub>4</sub>N <sub>0</sub>M <sub>0</sub> in 6 cases, T <sub>4</sub>N <sub>2</sub>M <sub>0</sub> in 1 case; American Joint Committee on Cancer (AJCC) staging in 2017 was stage Ⅳ. Preoperative MRI angiography of upper arm was performed to investigate the blood supply in the upper and lateral regions of the upper arm. After near-total laryngectomy and bilateral neck lymph node dissection, the area of the laryngotracheal defect was measured. A free flap measuring 7.0 cm×5.0 cm to 8.0 cm×7.0 cm was harvested from the upper-lateral upper arm, rolled into a tube shape, and connected between the stump of the cervical trachea in the neck root and that of the epiglottis at the tongue base. Four patients received adjuvant radiochemotherapy, 1 patient received radiochemotherapy and targeted therapy, 2 patients adopted no further adjuvant treatment.</p><p><strong>Results: </strong>All 7 patients were followed-up 1-2 years (mean, 1 year and 3 months). Four patients had primary wound healing, 2 patients had minor pharyngeal fistulas that healed after dressing change, 1 patient experienced pharyngeal fistula because of flap necrosis and the wound still healed without secondary surgery. All patients took food orally within 1 month after operation, and the tracheal cannula was retained. Six patients with survived flap gradually adapted to their new pronunciation mode and obtained satisfactory phonatory function from 15 days to 2 months after operation. Four patients had slight aspiration after operation. Till the end of the follow-up, all patients survived and no local recurrence or distant metastasis had been observed. The motor function of the upper arm was not affected, only partial sensory loss occurred in the area near the incision. The scar of the incision could be covered by the short sleeve so as to obtain a better aesthetic effect.</p><p><strong>Conclusion: </strong>Using a tubular free flap from upper-lateral upper arm to repair the laryngotracheal circumferential defect after near-total laryngectomy for laryngeal cancer can achieve satisfactory phonatory restoration while preserve the motor function and aesthetics of the donor site.</p>","PeriodicalId":23979,"journal":{"name":"中国修复重建外科杂志","volume":"39 2","pages":"209-214"},"PeriodicalIF":0.0,"publicationDate":"2025-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11839294/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143459773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Short-term effectiveness of anterior and middle columns repair and reconstruction with whole autogenous spinous process-laminar bone through posterior approach in thoracolumbar tuberculosis].
中国修复重建外科杂志 Pub Date : 2025-02-15 DOI: 10.7507/1002-1892.202412008
Hongwei Chen, Tao Li, Hua Chen, Peng Xiu
{"title":"[Short-term effectiveness of anterior and middle columns repair and reconstruction with whole autogenous spinous process-laminar bone through posterior approach in thoracolumbar tuberculosis].","authors":"Hongwei Chen, Tao Li, Hua Chen, Peng Xiu","doi":"10.7507/1002-1892.202412008","DOIUrl":"10.7507/1002-1892.202412008","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;To investigate the short-term effectiveness of the anterior and middle columns in thoracolumbar tuberculosis reconstructed with whole autogenous spinous process-laminar bone through posterior approach.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;The retrospective study included 78 patients with thoracolumbar tuberculosis who underwent posterior approach surgery and anterior and middle column bone graft reconstruction between January 2012 and May 2023. Based on the type of autogenous bone graft used, patients were divided into group A (whole autogenous spinous process-laminar bone graft, 38 cases) and group B (autogenous structural iliac bone graft, 40 cases). There was no significant difference of baseline data, such as age, gender, disease duration, involved segment of spinal tuberculosis, and preoperative erythrocyte sedimentation rate (ESR), C reactive protein (CRP), Oswestry disability index (ODI), visual analogue scale (VAS) score, the American Spinal Injury Association (ASIA) grade, segmental kyphotic angle, and intervertebral height between the two groups ( &lt;i&gt;P&lt;/i&gt;&gt;0.05). The operation time, intraoperative blood loss, postoperative drainage, hospital stays, ESR, CRP, VAS score, ODI, bone fusion time, ASIA grade for neurological status valuation, postoperative complications, change of segmental kyphotic angle, change of intervertebral height were recorded and compared between the two groups.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;The operation time in group A was significantly shorter than that in group B ( &lt;i&gt;P&lt;/i&gt;&lt;0.05); there was no significant difference in intraoperative blood loss, postoperative drainage, and hospital stays between the two groups ( &lt;i&gt;P&lt;/i&gt;&gt;0.05). All patients in the two groups were followed up 14-110 months (mean, 64.1 months); there was no significant difference in the follow-up time between the two groups ( &lt;i&gt;P&lt;/i&gt;&gt;0.05). The ESR, CRP, ODI, and VAS score at each time point after operation in both groups significantly improved when compared with those before operation, and further improved with the extension of time, the differences were significant ( &lt;i&gt;P&lt;/i&gt;&lt;0.05). There was no significant difference between the two groups ( &lt;i&gt;P&lt;/i&gt;&gt;0.05) except that the VAS score of group A was significantly better than that of group B at 3 days after operation ( &lt;i&gt;P&lt;/i&gt;&lt;0.05). There was no significant difference in fusion time between the two groups ( &lt;i&gt;P&lt;/i&gt;&gt;0.05). The neurological function of most patients improved after operation, and there was no significant difference in ASIA grade between the two groups at last follow-up ( &lt;i&gt;P&lt;/i&gt;&gt;0.05). There was no significant difference in segmental kyphosis angle and intervertebral height between the two groups at each time point ( &lt;i&gt;P&lt;/i&gt;&gt;0.05), and no significant difference in segmental kyphosis angle, intervertebral height correction and loss were found between the two groups ( &lt;i&gt;P&lt;/i&gt;&gt;0.05). In group A, there was 1 case of incision fat liquefaction and 1 case of","PeriodicalId":23979,"journal":{"name":"中国修复重建外科杂志","volume":"39 2","pages":"201-208"},"PeriodicalIF":0.0,"publicationDate":"2025-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11839297/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143459809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Research progress in surgical techniques for treatment of limb lymphedema].
中国修复重建外科杂志 Pub Date : 2025-02-15 DOI: 10.7507/1002-1892.202411016
Ting He, Zewen Wang, Tao Zhang, Fan Yang, Baoyi Liu
{"title":"[Research progress in surgical techniques for treatment of limb lymphedema].","authors":"Ting He, Zewen Wang, Tao Zhang, Fan Yang, Baoyi Liu","doi":"10.7507/1002-1892.202411016","DOIUrl":"10.7507/1002-1892.202411016","url":null,"abstract":"<p><strong>Objective: </strong>To review the latest research advancements in surgical techniques for the treatment of limb lymphedema.</p><p><strong>Methods: </strong>The relevant literature at home and abroad in recent years was extensively reviewed, and the research on the treatment of limb lymphedema by surgical techniques were summarized and analyzed.</p><p><strong>Results: </strong>Lymphovenous anastomosis has demonstrated good effectiveness for early to mid-stage limb lymphedema, however its long-term effectiveness and applicability for late-stage limb lymphedema still require further validation. Autologous lymphatic/venous grafting has shown clinical feasibility in the treatment of secondary limb lymphedema. Research on tissue-engineered lymphatic scaffolds remains insufficient, primarily due to the complexity of lymphatic anatomical structures and the technical challenges involved. Nevertheless, its potential application is promising. Vascularized lymph node flap transplantation has shown significant effectiveness in treating limb lymphedema, particularly yielding good outcomes in upper limb cases. However, it can not guarantee a complete cure for the condition. Charles' operation is the most effective treatment option for patients with late-stage limb lymphedema, but its extensive incision and severe postoperative complications limit its application. Liposuction has the advantages such as minimal invasiveness, high safety, and repeatability. It is suitable for patients with late-stage limb lymphedema who have failed conservative treatment or developed adiposity. However, its effectiveness is limited in patients with significant limb fibrosis.</p><p><strong>Conclusion: </strong>Current treatments for limb lymphedema require further improvement, and there is considerable debate regarding treatment strategies for different stages of the condition. Future high-quality, multi-system combined treatment approaches are anticipated to guide clinical practice.</p>","PeriodicalId":23979,"journal":{"name":"中国修复重建外科杂志","volume":"39 2","pages":"230-236"},"PeriodicalIF":0.0,"publicationDate":"2025-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11839289/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143459723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Posterior minimally invasive approach for treatment of posterior wall acetabular fractures].
中国修复重建外科杂志 Pub Date : 2025-02-15 DOI: 10.7507/1002-1892.202411038
Wenbo Li, Lihong Liu, Peisheng Shi, Yun Xue, Wei Wang, Jie Shi, Chuangbing Li, Xianqing Shi, Xiaowen Deng, Qiuming Gao
{"title":"[Posterior minimally invasive approach for treatment of posterior wall acetabular fractures].","authors":"Wenbo Li, Lihong Liu, Peisheng Shi, Yun Xue, Wei Wang, Jie Shi, Chuangbing Li, Xianqing Shi, Xiaowen Deng, Qiuming Gao","doi":"10.7507/1002-1892.202411038","DOIUrl":"10.7507/1002-1892.202411038","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;To investigate the effectiveness of posterior minimally invasive approach in the treatment of posterior wall acetabular fractures.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;The clinical data of 17 patients with posterior wall acetabular fractures treated with posterior minimally invasive approach between March 2019 and June 2023 were retrospectively analyzed. There were 14 males and 3 females with an average age of 41 years ranging from 28 to 57 years. The causes of injury were traffic accident in 12 cases and falling from height in 5 cases. There were 3 cases complicated with posterior hip dislocation and 2 cases complicated with sciatic nerve injury. According to AO/Orthopaedic Trauma Association (AO/OTA) classification, there were 11 cases of type A1.1 and 6 cases of type A1.2. The time from injury to operation was 5-8 days, with an average of 6.2 days. The incision length, intraoperative blood loss, and operation time were recorded. The quality of posterior wall fracture reduction were evaluated by Matta criteria, and hip function were evaluated by modified Merle d'Aubign-Postel score criteria at 6 months after operation and last follow-up.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;The operation was successfully completed in 17 cases. The length of incision ranged from 7 to 9 cm, with an average of 8.3 cm, and all incisions healed by first intention. The intraoperative blood loss ranged from 200 to 350 mL, with an average of 281 mL. The operation time ranged from 45 to 70 minutes, with an average of 57 minutes. Two patients had sciatic nerve injury before operation, and the sciatic nerve function recovered completely at 3 months after operation; the other 15 patients had no symptoms of sciatic nerve injury after operation. All the 17 patients were followed up 14-27 months, with an average of 19.5 months. At 1 week after operation, according to the Matta criteria, anatomical reduction was achieved in 12 cases and satisfactory reduction in 5 cases, with a satisfaction rate of 100%. According to the modified Merle d'Aubign-Postel scoring system, the hip function score was 13-18 (mean, 16.1) at 6 months after operation. Among them, 5 cases were excellent, 9 were good, and 3 were fair, with an excellent and good rate of 82.4%. At last follow-up, the hip function score was 7-18 (mean, 13.7), of which 3 cases were excellent, 9 were good, 3 were fair, and 2 were poor, with an excellent and good rate of 70.6%. During the follow-up, there was no infection, failure of internal fixation, and femoral head necrosis, and heterotopic ossification occurred in 2 cases.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;The posterior minimally invasive approach has the advantages of less trauma, shorter operation time, less blood loss, without cutting off the external rotator muscle. Exposure through the gluteus medius-piriformis space and piriformis-supercilium space can provide sufficient safe exposure for the posterior wall acetabulum fracture, which is a reliabl","PeriodicalId":23979,"journal":{"name":"中国修复重建外科杂志","volume":"39 2","pages":"134-139"},"PeriodicalIF":0.0,"publicationDate":"2025-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11839302/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143459743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Preliminary study on preparation of decellularized nerve grafts from GGTA1 gene-edited pigs and their immune rejection in xenotransplantation].
中国修复重建外科杂志 Pub Date : 2025-02-15 DOI: 10.7507/1002-1892.202408052
Yuli Liu, Jinjuan Zhao, Xiangyu Song, Zhibo Jia, Chaochao Li, Tieyuan Zhang, Xiangling Li, Shi Yan, Ruichao He, Jiang Peng
{"title":"[Preliminary study on preparation of decellularized nerve grafts from GGTA1 gene-edited pigs and their immune rejection in xenotransplantation].","authors":"Yuli Liu, Jinjuan Zhao, Xiangyu Song, Zhibo Jia, Chaochao Li, Tieyuan Zhang, Xiangling Li, Shi Yan, Ruichao He, Jiang Peng","doi":"10.7507/1002-1892.202408052","DOIUrl":"10.7507/1002-1892.202408052","url":null,"abstract":"<p><strong>Objective: </strong>To prepare decellularized nerve grafts from alpha-1, 3-galactosyltransferase (GGTA1) gene-edited pigs and explore their biocompatibility for xenotransplantation.</p><p><strong>Methods: </strong>The sciatic nerves from wild-type pigs and GGTA1 gene-edited pigs were obtained and underwent decellularization. The alpha-galactosidase (α-gal) content in the sciatic nerves of GGTA1 gene-edited pigs was detected by using IB4 fluorescence staining and ELISA method to verify the knockout status of the GGTA1 gene, and using human sciatic nerve as a control. HE staining and scanning electron microscopy observation were used to observe the structure of the nerve samples. Immunofluorescence staining and DNA content determination were used to evaluate the degree of decellularization of the nerve samples. Fourteen nude mice were taken, and subcutaneous capsules were prepared on both sides of the spine. Decellularized nerve samples of wild-type pigs ( <i>n</i>=7) and GGTA1 gene-edited pigs ( <i>n</i>=7) were randomly implanted in the subcutaneous capsules. Blood was drawn at 1, 3, 5, and 7 days after implantation to detect neutrophil counting.</p><p><strong>Results: </strong>IB4 fluorescence staining and ELISA detection showed that GGTA1 gene was successfully knocked out in the nerves of GGTA1 gene-edited pigs. HE staining showed that the structure of the decellularized nerve from GGTA1 gene-edited pigs was well preserved; the nerve basement membrane tube structure was visible under scanning electron microscopy; no cell nuclei was observed, and the extracellular matrix components was retained in the nerve grafts by immunofluorescence staining; and the DNA content was significantly reduced when compared with the normal nerves ( <i>P</i><0.05). <i>In vivo</i> experiments showed that the number of neutrophils in the two groups were similar at 1, 3, and 7 days after implantation, with no significant difference ( <i>P</i>>0.05); only at 5 days, the number of neutrophils was significantly lower in the GGTA1 gene-edited pigs than in the wild-type pigs ( <i>P</i><0.05).</p><p><strong>Conclusion: </strong>The decellularized nerve grafts from GGTA1 gene-edited pigs have well-preserved nerve structure, complete decellularization, retain the natural nerve basement membrane tube structure and components, and low immune response after xenotransplantation through <i>in vitro</i> experiments.</p>","PeriodicalId":23979,"journal":{"name":"中国修复重建外科杂志","volume":"39 2","pages":"224-229"},"PeriodicalIF":0.0,"publicationDate":"2025-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11839286/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143459765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Early effectiveness of navigation-free robot-assisted total knee arthroplasty in treating knee osteoarthritis with extra-articular deformities].
中国修复重建外科杂志 Pub Date : 2025-01-15 DOI: 10.7507/1002-1892.202408061
Chen Meng, Yongqing Xu, Rongmao Shi, Luqiao Pu, Jian'an Ji, Xingyou Yao, Xizong Zhou, Chuan Li
{"title":"[Early effectiveness of navigation-free robot-assisted total knee arthroplasty in treating knee osteoarthritis with extra-articular deformities].","authors":"Chen Meng, Yongqing Xu, Rongmao Shi, Luqiao Pu, Jian'an Ji, Xingyou Yao, Xizong Zhou, Chuan Li","doi":"10.7507/1002-1892.202408061","DOIUrl":"10.7507/1002-1892.202408061","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the early effectiveness of navigation-free robot-assisted total knee arthroplasty (TKA) compared to traditional TKA in the treatment of knee osteoarthritis combined with extra-articular deformities.</p><p><strong>Methods: </strong>The clinical data of 30 patients with knee osteoarthritis combined with extra-articular deformities who met the selection criteria between June 2019 and January 2024 were retrospectively analyzed. Fifteen patients underwent CORI navigation-free robot-assisted TKA and intra-articular osteotomy (robot group) and 15 patients underwent traditional TKA and intra-articular osteotomy (traditional group). There was no significant difference in age, gender, body mass index, affected knee side, extra-articular deformity angle, deformity position, deformity type, and preoperative knee range of motion, American Knee Society (KSS) knee score and KSS function score, and lower limb alignment deviation between the two groups ( <i>P</i>>0.05). The operation time, intraoperative blood loss, and complications of the two groups were recorded and compared. The knee range of motion and lower limb alignment deviation were recorded before operation and at 6 months after operation, and the knee joint function was evaluated by KSS knee score and function score.</p><p><strong>Results: </strong>There was no significant difference in operation time between the two groups ( <i>P</i>>0.05); the intraoperative blood loss in the robot group was significantly less than that in the traditional group ( <i>P</i><0.05). Patients in both groups were followed up 6-12 months, with an average of 8.7 months. The incisions of all patients healed well, and there was no postoperative complication such as thrombosis or infection. At 6 months after operation, X-ray examination showed that the position of the prosthesis was good in both groups, and there was no loosening or dislocation of the prosthesis. The knee joint range of motion, the lower limb alignment deviation, and the KSS knee score and KSS function score significantly improved in both groups ( <i>P</i><0.05) compared to preoperative ones. The changes of lower limb alignment deviation and KSS function score between pre- and post-operation in the robot group were significantly better than those in the traditional group ( <i>P</i><0.05), while the changes of other indicators between pre- and post-operation in the two groups were not significant ( <i>P</i>>0.05).</p><p><strong>Conclusion: </strong>Compared to traditional TKA, navigation-free robot-assisted TKA for knee osteoarthritis with extra-articular deformities results in less intraoperative blood loss, more precise reconstruction of lower limb alignment, and better early effectiveness. However, long-term effectiveness require further investigation.</p>","PeriodicalId":23979,"journal":{"name":"中国修复重建外科杂志","volume":"39 1","pages":"5-12"},"PeriodicalIF":0.0,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11757961/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143029834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Revision of anterior cruciate ligament reconstruction: Interpretation of the consensus by the European Society of Sports Traumatology, Knee Surgery and Arthroscopy (ESSKA)].
中国修复重建外科杂志 Pub Date : 2025-01-15 DOI: 10.7507/1002-1892.202409090
Mingjin Zhong, Kan Ouyang
{"title":"[Revision of anterior cruciate ligament reconstruction: Interpretation of the consensus by the European Society of Sports Traumatology, Knee Surgery and Arthroscopy (ESSKA)].","authors":"Mingjin Zhong, Kan Ouyang","doi":"10.7507/1002-1892.202409090","DOIUrl":"10.7507/1002-1892.202409090","url":null,"abstract":"<p><p>Revision of anterior cruciate ligament (ACL) reconstruction is more challenging than primary ACL reconstruction and often yields less favorable outcomes. The European Society of Sports Traumatology, Knee Surgery and Arthroscopy (ESSKA) has established a consensus regarding preoperative diagnosis, assessment, and selection criteria for ACL revision surgery. This consensus addresses 18 key issues that are most pertinent to clinical practice, providing guiding recommendations aimed at improving the prognosis of ACL revisions.</p>","PeriodicalId":23979,"journal":{"name":"中国修复重建外科杂志","volume":"39 1","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11757958/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143029934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Effectiveness analysis of three internal fixation methods in treatment of avulsion fracture of tibial tubercle in adolescents].
中国修复重建外科杂志 Pub Date : 2025-01-15 DOI: 10.7507/1002-1892.202410025
Keyou Duan, Zhaodong Wang, Yajun Liu, Chen Xu, Zhonglian Zhu, Jianzhong Guan
{"title":"[Effectiveness analysis of three internal fixation methods in treatment of avulsion fracture of tibial tubercle in adolescents].","authors":"Keyou Duan, Zhaodong Wang, Yajun Liu, Chen Xu, Zhonglian Zhu, Jianzhong Guan","doi":"10.7507/1002-1892.202410025","DOIUrl":"10.7507/1002-1892.202410025","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;To analyze the effectiveness of three internal fixation methods, namely hollow screw combined with Kirschner wire tension band, hollow screw combined with anchor nail, and modified 1/3 tubular steel plate, in the treatment of avulsion fracture of tibial tubercle (AFTT) in adolescents.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;Between January 2018 and September 2023, 19 adolescent AFTT patients who met the selection criteria were admitted. According to different internal fixation methods, patients were divided into group A (8 cases, hollow screw combined with Kirschner wire tension band), group B (6 cases, hollow screw combined with anchor nail), and group C (5 cases, modified 1/3 tubular steel plate). There was no significant difference in the baseline data of age, gender, side, cause of injury, Ogden classification, and time from injury to operation among the three groups ( &lt;i&gt;P&lt;/i&gt;&gt;0.05). The range of motion (ROM), weight-bearing time, normal activity time of knee joint, and the hospital for special surgery (HSS) score at last follow-up were recorded and compared among the three groups. Recorded whether the fracture was displaced, whether the fracture line was blurred at 1 month after operation, whether there was epiphyseal dysplasia, and whether there was incision infection and other complications.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;There was no significant difference in hospital stay between the groups ( &lt;i&gt;P&lt;/i&gt;&gt;0.05). All patients were followed up 10-24 months, with an average of 14.3 months; there was no significant difference between the groups ( &lt;i&gt;P&lt;/i&gt;&gt;0.05). All the incisions healed well without soft tissue irritation or fracture nonunion, and no limb shortening deformity or epiphyseal dysplasia was found during follow-up. At 1 month after operation, the knee joint ROM and hospitalization expenses in group A were better than those in groups B and C, the fracture healing time, knee joint weight-bearing time, and normal activity time of knee joint were better than those in group C, and the hospitalization expenses in group C were better than those in group B, with significant differences ( &lt;i&gt;P&lt;/i&gt;&lt;0.05); there was no significant difference in the other indicators between the groups ( &lt;i&gt;P&lt;/i&gt;&gt;0.05). In group A, the fracture line was blurred 1 month postoperatively, the fracture ends were in close contact, and there was no fracture displacement; in groups B and C, the fracture line was clear in 2 cases, and 1 case in group C had slight fracture displacement; except for 1 case in group B, there was no fracture split in the other two groups. There was no significant difference in the incidences of blur of fracture line, fracture displacement, and intraoperative bone split between the groups at 1 month after operation ( &lt;i&gt;P&lt;/i&gt;&gt;0.05). At last follow-up, the HSS scores of knee joints in the three groups were excellent and good, and there was no significant difference between the groups ( &lt;i&gt;P&lt;/i&gt;&gt;0.05).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conc","PeriodicalId":23979,"journal":{"name":"中国修复重建外科杂志","volume":"39 1","pages":"75-82"},"PeriodicalIF":0.0,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11757965/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143029838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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