Zentralblatt fur Chirurgie最新文献

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[Local Therapy in Stage IV Lung Cancer with Oligopersistent or Oligoprogessive Disease]. [IV期肺癌伴有低度持续性或低度浸润性疾病的局部治疗]
IF 0.5 4区 医学
Zentralblatt fur Chirurgie Pub Date : 2024-08-01 Epub Date: 2024-08-13 DOI: 10.1055/a-2351-4358
Christian Schulz
{"title":"[Local Therapy in Stage IV Lung Cancer with Oligopersistent or Oligoprogessive Disease].","authors":"Christian Schulz","doi":"10.1055/a-2351-4358","DOIUrl":"https://doi.org/10.1055/a-2351-4358","url":null,"abstract":"<p><p>Oligopersistent and oligoprogressive disease are defined as distinct situations of metastastatic lung cancer. Oligopersistence describes a situation in which a limited number of metastases remain following effective systemic therapy. Oligoprogression represents a largely controlled tumour disease with a few metastases showing significant progression. In the oligopersistence, treatment aims to establish complete tumour control with subsequent improvement of the prognosis by means of additional local ablative treatment of all remaining lesions. In the oligoprogressive situation, local ablative treatment aims to reestablish complete tumour control while continuing systemic therapy. The concepts are based on ideas that were introduced in oncology more than 30 years ago by Hellman and Weichselbaum by using the term oligometastases. Multimodal therapy concepts have gained importance in the situation of oligopersistence and oligoprogression, particularly due to molecular targeted therapies for oncogene-driven lung cancer and chemo-immunotherapy regimes with high response rates and long response duration. The available evidence will be presented and explained by case studies.</p>","PeriodicalId":23956,"journal":{"name":"Zentralblatt fur Chirurgie","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141976789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Pathological Diagnostic Testing and Biomarkers for Perioperative System Therapy]. [围手术期系统治疗的病理诊断测试和生物标记物]。
IF 0.5 4区 医学
Zentralblatt fur Chirurgie Pub Date : 2024-08-01 Epub Date: 2024-08-13 DOI: 10.1055/a-2359-2150
Ramona Erber
{"title":"[Pathological Diagnostic Testing and Biomarkers for Perioperative System Therapy].","authors":"Ramona Erber","doi":"10.1055/a-2359-2150","DOIUrl":"https://doi.org/10.1055/a-2359-2150","url":null,"abstract":"<p><p>Optimal personalized treatment planning for resectable lung cancer requires quality-assured, standardized and prompt processing of tissue samples in pathological laboratories, as well as the determination of relevant predictive and prognostic biomarkers. Pathological diagnostic testing includes histological tumor typing, staging and tumor grading, resection status and, if necessary, regression grading after neoadjuvant systemic therapy. Histopathological typing is performed according to the current WHO classification and includes adenocarcinomas, squamous cell carcinomas, other non-small cell lung carcinomas (NSCLCs), carcinoids, small cell and large cell neuroendocrine carcinomas. Standardized tumor grading currently plays an important role in invasive non-mucinous adenocarcinoma in particular and enables prognostic risk assessment. The R classification and regression grading are also prognostically relevant. In the early stages of NSCLC, molecular biomarkers such as EGFR, ALK and PD-L1, are relevant for decisions on individual treatment. Testing is performed on FFPE tissue samples and must be carried out in a quality-assured manner and in accordance with international standards.</p>","PeriodicalId":23956,"journal":{"name":"Zentralblatt fur Chirurgie","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141976801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mitteilungen der DGT im Zentralblatt für Chirurgie. 在 Zentralblatt für Chirurgie 上发布 DGT 公告。
IF 0.5 4区 医学
Zentralblatt fur Chirurgie Pub Date : 2024-08-01 Epub Date: 2024-08-13 DOI: 10.1055/a-2359-3373
{"title":"Mitteilungen der DGT im Zentralblatt für Chirurgie.","authors":"","doi":"10.1055/a-2359-3373","DOIUrl":"https://doi.org/10.1055/a-2359-3373","url":null,"abstract":"","PeriodicalId":23956,"journal":{"name":"Zentralblatt fur Chirurgie","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141976805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Vascularsurgical Long-term Outcome - Comparison of Orthotopic and Extraanatomic Reconstructions in Unilateral Occlusions of Iliac Artery over 10 Years]. [血管外科手术的长期效果--10 年内髂动脉单侧闭塞症矫形重建与体外重建的比较]。
IF 0.7 4区 医学
Zentralblatt fur Chirurgie Pub Date : 2024-06-17 DOI: 10.1055/a-2324-1692
Udo Barth, Jörg Tautenhahn, Philipp Klinsmann, Frank Meyer, Zuhir Halloul
{"title":"[Vascularsurgical Long-term Outcome - Comparison of Orthotopic and Extraanatomic Reconstructions in Unilateral Occlusions of Iliac Artery over 10 Years].","authors":"Udo Barth, Jörg Tautenhahn, Philipp Klinsmann, Frank Meyer, Zuhir Halloul","doi":"10.1055/a-2324-1692","DOIUrl":"https://doi.org/10.1055/a-2324-1692","url":null,"abstract":"<p><p>In PAOD, several vascular regions are usually affected, the pelvic axis in 35% of cases. Interventional-radiological/endovascular or hybrid interventions have been established for recanalization, so that bypass procedures are increasingly taking a back seat, but are not losing their importance.To study unilateral iliac artery occlusions (inclusion criterion) that were repaired either by implantation of an orthotopic or extraanatomic bypass (oBP/eaBP).Over a defined period of time, the rate of open vessel, complications (frequency, type, severity) to characterize morbidity and mortality as well as the extent of clinical improvement after BP implantation were analyzed in a clinical-systematic, single-center observational study (for vascular surgical quality assurance and contribution to vascular medical-clinical health care research). The study method was not explicitly based on the STROBE criteria, but essentially corresponds to them.Over 10 years, 122 PAOD patients (50% in stage IIb-stage III and IV equally distributed; mean age: 63 [range, 44-87] years; majority ASA III) were included with the same number of reconstructions: 71 patients received an eaBP (\"crossover\"), 51 patients an iliacofemoral (orthotopic - oBP) bypass (neither significant difference regarding frequency nor number of risk factors per patient).The oBP is not superior to eaBP with regard to the analysis parameters of openness, complication rate and mortality. Furthermore, extraanatomic revascularization does not have to be reserved for polymorbid patients only.</p>","PeriodicalId":23956,"journal":{"name":"Zentralblatt fur Chirurgie","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2024-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141421161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Carinal Resections]. [Carinal Resections].
IF 0.7 4区 医学
Zentralblatt fur Chirurgie Pub Date : 2024-06-01 Epub Date: 2024-02-15 DOI: 10.1055/a-2240-9974
Alberto Lopez-Pastorini, Erich Stoelben
{"title":"[Carinal Resections].","authors":"Alberto Lopez-Pastorini, Erich Stoelben","doi":"10.1055/a-2240-9974","DOIUrl":"10.1055/a-2240-9974","url":null,"abstract":"<p><p>Carinal resections are consistently described in the literature as one of the most challenging procedures in thoracic surgery. Depending on the underlying disease and its extent, different resection forms and reconstruction techniques are required. From a surgical point of view, the complex anatomy, and the technique of reconstruction of the central airway are particularly challenging. However, complex airway management and extensive postoperative follow-up demonstrate that these procedures require a multidisciplinary team effort beyond surgical expertise. This article reviews the most important pre-, intra-, and post-operative aspects of these challenging procedures.</p>","PeriodicalId":23956,"journal":{"name":"Zentralblatt fur Chirurgie","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139742178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mitteilungen der DGT im Zentralblatt für Chirurgie. 在 Zentralblatt für Chirurgie 上发布 DGT 公告。
IF 0.7 4区 医学
Zentralblatt fur Chirurgie Pub Date : 2024-06-01 Epub Date: 2024-06-05 DOI: 10.1055/a-2301-7141
{"title":"Mitteilungen der DGT im Zentralblatt für Chirurgie.","authors":"","doi":"10.1055/a-2301-7141","DOIUrl":"https://doi.org/10.1055/a-2301-7141","url":null,"abstract":"","PeriodicalId":23956,"journal":{"name":"Zentralblatt fur Chirurgie","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141260488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Objektivierung der Versorgungsqualität in der Viszeralchirurgie. 内脏外科护理质量的客观化。
IF 0.7 4区 医学
Zentralblatt fur Chirurgie Pub Date : 2024-06-01 Epub Date: 2024-06-05 DOI: 10.1055/a-2280-5655
Sophie Müller
{"title":"Objektivierung der Versorgungsqualität in der Viszeralchirurgie.","authors":"Sophie Müller","doi":"10.1055/a-2280-5655","DOIUrl":"https://doi.org/10.1055/a-2280-5655","url":null,"abstract":"","PeriodicalId":23956,"journal":{"name":"Zentralblatt fur Chirurgie","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141260577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Tracheal Tumours]. [气管肿瘤]
IF 0.7 4区 医学
Zentralblatt fur Chirurgie Pub Date : 2024-06-01 Epub Date: 2024-02-21 DOI: 10.1055/a-2223-1175
Florian Eichhorn, Hans Hoffmann, Stefan Rieken, Felix J F Herth, Hauke Winter
{"title":"[Tracheal Tumours].","authors":"Florian Eichhorn, Hans Hoffmann, Stefan Rieken, Felix J F Herth, Hauke Winter","doi":"10.1055/a-2223-1175","DOIUrl":"10.1055/a-2223-1175","url":null,"abstract":"<p><p>Malignant primary tracheal tumours are rare. The most common histological subtypes are squamous cell carcinoma and adenoid cystic carcinoma. These two entities have different prognoses and growth patterns. Tracheobronchoscopy and thoracic sectional imaging are standard diagnostic tools for tumour staging and local evaluation. Complete surgical resection of the affected tracheal segment is the treatment of choice for limited disease without distant metastases. Incomplete gross tumour resection with additional irradiation is an acceptable therapeutic option for adenoid cystic carcinoma. Interventional endoscopy with tumour debulking or tracheal stenting and/or definitive mediastinal radiotherapy are treatment alternatives in either a locally advanced or palliative setting.</p>","PeriodicalId":23956,"journal":{"name":"Zentralblatt fur Chirurgie","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139933107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Robotic Pancreatoduodenectomy: Variations of Modified Blumgarts Pancreatojejunostomy]. [机器人胰十二指肠切除术:改良布隆加茨胰空肠吻合术的变体]。
IF 0.7 4区 医学
Zentralblatt fur Chirurgie Pub Date : 2024-06-01 Epub Date: 2024-01-09 DOI: 10.1055/a-2194-0785
Philipp Seeger, Marius Distler, Michael Thomaschewski, Markus Zimmermann, Asmus Heumann, Faik Güntac Uzunoglu, Robert Grützmann, Georg F Weber, Maximilian Brunner, Stephan Kersting, Thilo Hackert, Tobias Keck, Felix Nickel
{"title":"[Robotic Pancreatoduodenectomy: Variations of Modified Blumgarts Pancreatojejunostomy].","authors":"Philipp Seeger, Marius Distler, Michael Thomaschewski, Markus Zimmermann, Asmus Heumann, Faik Güntac Uzunoglu, Robert Grützmann, Georg F Weber, Maximilian Brunner, Stephan Kersting, Thilo Hackert, Tobias Keck, Felix Nickel","doi":"10.1055/a-2194-0785","DOIUrl":"10.1055/a-2194-0785","url":null,"abstract":"","PeriodicalId":23956,"journal":{"name":"Zentralblatt fur Chirurgie","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139404553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Die Auswirkungen mangelhafter Patientencompliance. 病人依从性差的影响。
IF 0.5 4区 医学
Zentralblatt fur Chirurgie Pub Date : 2024-06-01 Epub Date: 2024-06-05 DOI: 10.1055/a-2178-7194
Kim-Victoria Seibert, Albrecht Wienke
{"title":"Die Auswirkungen mangelhafter Patientencompliance.","authors":"Kim-Victoria Seibert, Albrecht Wienke","doi":"10.1055/a-2178-7194","DOIUrl":"10.1055/a-2178-7194","url":null,"abstract":"","PeriodicalId":23956,"journal":{"name":"Zentralblatt fur Chirurgie","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141260205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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