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Computers in Cardiology, 2005最新文献

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On the role of gap junctions in cardiac memory effect 间隙连接在心脏记忆效应中的作用
Computers in Cardiology, 2005 Pub Date : 1900-01-01 DOI: 10.1109/CIC.2005.1588020
J. Krishnan, V. Chakravarthy, S. Radhakrishnan
{"title":"On the role of gap junctions in cardiac memory effect","authors":"J. Krishnan, V. Chakravarthy, S. Radhakrishnan","doi":"10.1109/CIC.2005.1588020","DOIUrl":"https://doi.org/10.1109/CIC.2005.1588020","url":null,"abstract":"Memory in the nervous system is essentially a network effect, resulting from synaptic adaptation in a network of neurons. The heart too is a network of cardiac cells electrically coupled by gap junctions, which, we hypothesize, adapt as a function of the state of cellular depolarization. Cardiac memory, which refers to persistent effect of external stimulus on activation pattern, is demonstrated in a pair of model Noble cells with adaptive gap junctions. The memory seems to have a dual effect: while it dissipates small perturbations, it captures and imprints larger ones. The proposed memory mechanism is also shown to increase likelihood of synchronization among cardiac cells. Finally we argue that the proposed mechanism is linked to known electrophysiological properties of gap junctions","PeriodicalId":239491,"journal":{"name":"Computers in Cardiology, 2005","volume":"86 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126327245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
A dynamic 3-D cardiac surface model from MR images 磁共振图像的动态三维心脏表面模型
Computers in Cardiology, 2005 Pub Date : 1900-01-01 DOI: 10.1109/CIC.2005.1588127
B. Delhay, J. Lotjonen, P. Clarysse, T. Katila, I. Magnin
{"title":"A dynamic 3-D cardiac surface model from MR images","authors":"B. Delhay, J. Lotjonen, P. Clarysse, T. Katila, I. Magnin","doi":"10.1109/CIC.2005.1588127","DOIUrl":"https://doi.org/10.1109/CIC.2005.1588127","url":null,"abstract":"Cardiac 3D+time segmentation and motion estimation are recognized as difficult prerequisite tasks for any quantitative analysis of cardiac images. Some recent algorithms aim to consider a temporal constraint to increase the accuracy of results. To improve the temporal consistency, prior knowledge about cardiac dynamics can be used. In this paper, we propose to build a new Statistical Dynamic Model (SDM) of the heart by learning through a population of healthy individuals. This SDM is composed by a set of semi-landmarks which describe the heart surfaces. For each of them, a mean trajectory and variability around it are derived. The SDM provides a reasonable constraint for a temporally regularized segmentation and motion tracking algorithm","PeriodicalId":239491,"journal":{"name":"Computers in Cardiology, 2005","volume":"140 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125472393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
Fractionated repolarization induced by sotalol in healthy subjects 索他洛尔对健康人的分步复极作用
Computers in Cardiology, 2005 Pub Date : 1900-01-01 DOI: 10.1109/CIC.2005.1588153
M. Vaglio, J. Couderc, X. Xia, Wojciech Zareba
{"title":"Fractionated repolarization induced by sotalol in healthy subjects","authors":"M. Vaglio, J. Couderc, X. Xia, Wojciech Zareba","doi":"10.1109/CIC.2005.1588153","DOIUrl":"https://doi.org/10.1109/CIC.2005.1588153","url":null,"abstract":"Over the past five years, regulatory authorities have been increasingly concerned with QT prolongations induced by non-cardiac drug and have recommended pharmaceutical companies to include a careful assessment of the QT interval in their drug development programs. There are controversies around the predictive value of QT prolongation in safety-drug assessment studies. The prolongation of the QT interval is an imperfect, but accepted, surrogate marker of drug cardiac toxicity. In this study, we hypothesize that the inhomogeneous effect of QT-prolonging drug in the different layers of the myocardium would not only delay cardiac repolarization, but also perturb the repolarization wavefront on surface ECGs. Principal component analysis (PCA) was applied to the 12-lead ECG Holier recordings. The first two eigenvectors (ev1, ev2) were computed. From PCA, several parameters were calculated based on the first eigenvector and on the T-loop. We demonstrated slower repolarization and perturbed T-wave front; 30 min after sotalol administration, turbulence of repolarization velocity increased by 9.02%, p<0.05, occurring prior to QT prolongation. These abnormalities were mainly located in the ascending part of the T-wave, whereas the descending part seemed to be less affected at this early phase. In conclusion, analyzing repolarization morphology might help identifying early drug-induced repolarization changes, which could be missed when relying exclusively on QT measurements","PeriodicalId":239491,"journal":{"name":"Computers in Cardiology, 2005","volume":"68 5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131340123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
Detection of trabeculae and papillary muscles in cardiac MR images 心脏MR图像中小梁和乳头肌的检测
Computers in Cardiology, 2005 Pub Date : 1900-01-01 DOI: 10.1109/CIC.2005.1588125
L. Spreeuwers, S. Bangma, R. Meerwaldt, E. Vonken, M. Breeuwer
{"title":"Detection of trabeculae and papillary muscles in cardiac MR images","authors":"L. Spreeuwers, S. Bangma, R. Meerwaldt, E. Vonken, M. Breeuwer","doi":"10.1109/CIC.2005.1588125","DOIUrl":"https://doi.org/10.1109/CIC.2005.1588125","url":null,"abstract":"With the improvement of the quality of MR imagery, more and more details become visible. Only 5-10 years ago cardiac images of the heart were still so unsharp that finer details of the heart like the papillary muscles and the trabeculae were hardly visible and it was simply impossible to determine their outlines with any measure of accuracy. With the improved image quality it becomes feasible to extract information about these small structures. Studying the operation of these tiny muscles can be very useful for further analysis of the heart function and diagnosis of heart diseases. Until now very little literature existed on the study of these structures using cardiac MR, so with this publication we are riding the front of the wave. We conducted two pilot studies to investigate the feasibility of detection of papillary muscles in the left ventricular blood volume and to obtain a measure of the trabeculation of the right ventricle. The latter was also investigated as a diagnostic criterion for arrhythmogenic right ventricular dysplasia (ARVD)","PeriodicalId":239491,"journal":{"name":"Computers in Cardiology, 2005","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131362119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 17
Noninvasive visualization of three-dimensional atrial electrical excitation using anterior and posterior magnetocardiogram 利用前、后心磁图无创可视化三维心房电兴奋
Computers in Cardiology, 2005 Pub Date : 1900-01-01 DOI: 10.1109/CIC.2005.1588154
K. Ogata, A. Kandori, T. Miyashita, K. Tsukada, S. Nakatani, W. Shimizu, H. Kanzaki, K. Miyatake, S. Yamada, S. Watanabe, I. Yamaguchi
{"title":"Noninvasive visualization of three-dimensional atrial electrical excitation using anterior and posterior magnetocardiogram","authors":"K. Ogata, A. Kandori, T. Miyashita, K. Tsukada, S. Nakatani, W. Shimizu, H. Kanzaki, K. Miyatake, S. Yamada, S. Watanabe, I. Yamaguchi","doi":"10.1109/CIC.2005.1588154","DOIUrl":"https://doi.org/10.1109/CIC.2005.1588154","url":null,"abstract":"The aim of our work is to visualize three-dimensional (3-D) images of atrial excitation. We obtained these images by projecting the anterior and posterior current-arrow map (CAM), derived from a magnetocardiogram (MCG), onto a 3-D standard heart model. We generated the projected CAM (PCAM) of early and late atrial depolarization phases for fourteen healthy subjects. During early and late atrial excitation, the high-current areas of all subjects were in the right atrium of the anterior surface, and the left atrium of the posterior surface. The averaged ratio of the maximal current value of the early p-wave to the maximal current value of the late p-wave for all subjects was 0.9plusmn0.2. Furthermore, the averaged maximal current directions of the early and late p-wave were 78plusmn15 and 165plusmn17 degrees, respectively. Thus, we found that the PCAM could provide separated images of the left and right atrial excitations","PeriodicalId":239491,"journal":{"name":"Computers in Cardiology, 2005","volume":"136 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134201350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Validation results of a self-maintained cardiology collaborative tool 自我维护的心脏病学协作工具的验证结果
Computers in Cardiology, 2005 Pub Date : 1900-01-01 DOI: 10.1109/CIC.2005.1588081
E. del Hoyo-Barbolla, E. Conde, M. Arredondo, E. Villalba, M. Martínez‐Sellés, M. Mene
{"title":"Validation results of a self-maintained cardiology collaborative tool","authors":"E. del Hoyo-Barbolla, E. Conde, M. Arredondo, E. Villalba, M. Martínez‐Sellés, M. Mene","doi":"10.1109/CIC.2005.1588081","DOIUrl":"https://doi.org/10.1109/CIC.2005.1588081","url":null,"abstract":"Excellence in care optimisation in modern cardiology is a twofold issue that involves both the collaboration of numerous communities that benefit from collaborative work spaces as well as life-long education of professionals. Progressive specialisation of medical professionals is one of the factors that most account for this lack of dissemination giving way to the creation of clustered and specialised knowledge domains, only accessible to the elite of specialists and professional networks created around them. Besides, communication and collaboration among professionals proves to be quite scarce and hard outside restricted circles. This paper presents the results and lessons learnt from Health Memory (HM), a self-maintained multidisciplinary system that focuses on cardiology. It aims at enabling healthcare professionals (GPs, cardiologists, other, personnel, etc.), to address the management of knowledge and the enhancement of communication mechanisms","PeriodicalId":239491,"journal":{"name":"Computers in Cardiology, 2005","volume":"14 5","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133086509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The effects of transmission errors in ECG real-timewavelet compression codecs 传输误差对心电实时小波压缩编解码器的影响
Computers in Cardiology, 2005 Pub Date : 1900-01-01 DOI: 10.1109/CIC.2005.1588029
Á. Alesanco, R. Istepanian, J. García
{"title":"The effects of transmission errors in ECG real-timewavelet compression codecs","authors":"Á. Alesanco, R. Istepanian, J. García","doi":"10.1109/CIC.2005.1588029","DOIUrl":"https://doi.org/10.1109/CIC.2005.1588029","url":null,"abstract":"This paper discusses the error effects in wavelet compression codecs for real-time ECG monitoring in a wireless telecardiology application. Two different strategies for ECG coding are presented and the error effects in the received ECG signals are discussed. Both quantitative (RMS error index) and qualitative (cardiologist opinions) are presented in order to decide if it is useful to monitor retrieved information from ECG packets received with errors or erroneous packets should be discarded. Although RMS index suggests that it would be recommendable to show them, cardiologists conditioned their preference to the number of erroneous blocks in the monitoring process: few number of errors, monitoring no information; high number of errors, monitoring erroneous information","PeriodicalId":239491,"journal":{"name":"Computers in Cardiology, 2005","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131019400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Cross-departmental access to relevant clinical information for early rehabilitation using a web-based medical multimedia document server 使用基于web的医学多媒体文档服务器跨部门访问早期康复相关临床信息
Computers in Cardiology, 2005 Pub Date : 1900-01-01 DOI: 10.1109/CIC.2005.1588059
M. Eichelberg, K. Kronberg, D. Heidkamp, M. Grundler, O. Nee, H. Spekker
{"title":"Cross-departmental access to relevant clinical information for early rehabilitation using a web-based medical multimedia document server","authors":"M. Eichelberg, K. Kronberg, D. Heidkamp, M. Grundler, O. Nee, H. Spekker","doi":"10.1109/CIC.2005.1588059","DOIUrl":"https://doi.org/10.1109/CIC.2005.1588059","url":null,"abstract":"The \"Mobile Multimedia Medical Information System\" (M3IS) project develops a system that enables the exchange of clinical documents, medical images, films and laboratory results both within a hospital and between healthcare institutions. The system accepts documents through DICOM and HL7 interfaces and provides a Web-based client interface that allows for a quick and easy access to the system through a Web browser. In order to comply with data protection requirements, the system implements a powerful access control scheme. The system ensures that most clinically relevant document is available to early rehabilitation in a timely manner, before the final written discharge report becomes available","PeriodicalId":239491,"journal":{"name":"Computers in Cardiology, 2005","volume":"85 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130972059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Discrimination of herg carrier from non-carrier adult patients with borderline prolonged QTc interval 成人herg携带者与非携带者QTc间期延长的区别
Computers in Cardiology, 2005 Pub Date : 1900-01-01 DOI: 10.1109/CIC.2005.1588050
J. Couderc, W. Zareba, A. Moss
{"title":"Discrimination of herg carrier from non-carrier adult patients with borderline prolonged QTc interval","authors":"J. Couderc, W. Zareba, A. Moss","doi":"10.1109/CIC.2005.1588050","DOIUrl":"https://doi.org/10.1109/CIC.2005.1588050","url":null,"abstract":"Ten to fifteen percent of individual with the hereditary long-QT syndrome (LQTS) involving the human ether-a-go-go related gene (HERG) do not have an abnormal QT prolongation but are at risk of lethal arrhythmic event. We investigated the phenotypic T-wave morphology for the identification of patients with HERG mutations. The standard 12-lead ECGs from carrier and non-carrier LQT2 patients were digitized and the RR intervals and T-waves were quantified using QT/QTc, QT apex, T-wave amplitude, ascending (alphaL) and its descending slopes (alphaR). A logistic regression model selected 3 parameters for the classification of the groups: QT, RR and alphaL. The model provided 92.7% sensitivity and 90.0 % specificity. The information within the T-wave morphology is complementary to the information of repolarization duration. Abnormal T-wave morphology is a phenotypic expression of the HERG mutation in adult LQTS patient","PeriodicalId":239491,"journal":{"name":"Computers in Cardiology, 2005","volume":"218 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115525419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Web-based tool for management of CAD patients after coronary bypass surgery 基于网络的冠心病患者冠状动脉搭桥手术后管理工具
Computers in Cardiology, 2005 Pub Date : 1900-01-01 DOI: 10.1109/CIC.2005.1588058
A. Varoneckas, A. Mackute-Varoneckiene, A. Martinkenas, A. Zilinskas, G. Varoneckas
{"title":"Web-based tool for management of CAD patients after coronary bypass surgery","authors":"A. Varoneckas, A. Mackute-Varoneckiene, A. Martinkenas, A. Zilinskas, G. Varoneckas","doi":"10.1109/CIC.2005.1588058","DOIUrl":"https://doi.org/10.1109/CIC.2005.1588058","url":null,"abstract":"The purpose was to create a flexible system for biomedical data acquisition, analysis and archiving. Web-based tool includes centralized storage of data of coronary artery disease (CAD) patients after coronary artery bypass surgery (CABS) at different stages of treatment. The implemented Web based tool is based on client-server architecture and international open source technologies including Apache Web server, PHP scripts and MySQL database. The system implemented in client server architecture. The server stores the data and controls basic system functionalities. The client is used by users in order to access data from the server. The system should assure strict secure measures, that is why system is available only for authorized users. Web-based tool enable to monitor patient's functional state, to evaluate the effectiveness of treatment using novel methods of data visualization as well as to establish teleconsultations among doctor-doctor and patient-doctor-patient","PeriodicalId":239491,"journal":{"name":"Computers in Cardiology, 2005","volume":"48 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115910866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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