World Journal of Surgery最新文献

{"title":"Clinicopathological Features and Prognosis of Alpha-Fetoprotein-Producing Colorectal Cancer.","authors":"Maoshan Wang, Sheng Bi, Feipeng Wang, Zhenbo Shu, Zhongmin Li","doi":"10.1002/wjs.70555","DOIUrl":"https://doi.org/10.1002/wjs.70555","url":null,"abstract":"<p><strong>Background: </strong>Alpha-fetoprotein-producing colorectal cancer (AFPCRC) is an exceptionally rare subtype of colorectal cancer. Its clinicopathological features and prognostic implications remain poorly defined.</p><p><strong>Methods: </strong>In this retrospective matched cohort study, 6375 patients who underwent curative resection for colorectal cancer at the China-Japan Union Hospital of Jilin University from January 2020 to December 2024 were screened. A total of 46 patients with AFPCRC (defined by preoperative serum AFP levels > 7.0 ng/mL) were identified. A control group of 92 patients with non-AFPCRC was selected using 1:2 propensity score matching based on age, sex, and TNM stage. Clinicopathological features and survival outcomes were compared between the two groups. Patients with AFPCRC were further stratified into low- and high-AFP subgroups using their median preoperative serum AFP level (8.1 ng/mL) as the cutoff.</p><p><strong>Results: </strong>Compared with controls, patients with AFPCRC showed significantly higher rates of lymphovascular invasion, the presence of mucinous or signet-ring cell components, and distant metastasis during postoperative follow-up. Disease-free survival (DFS) was significantly shorter in the AFPCRC group than in the control group. TNM stage emerged as an independent predictor of DFS in the overall cohort (p = 0.036). In univariate analysis restricted to AFPCRC patients, preoperative serum AFP level (as a continuous variable) was significantly associated with DFS (p = 0.044).</p><p><strong>Conclusions: </strong>AFPCRC represents a rare but aggressive subtype of colorectal cancer, characterized by adverse clinicopathological features and a poor prognosis. Preoperative serum AFP level may serve as a useful prognostic biomarker in this patient population.</p>","PeriodicalId":23926,"journal":{"name":"World Journal of Surgery","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148913538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Seizure Rates in Mild and Moderate Traumatic Brain Injury With Intracranial Hemorrhage: A Signal for Prospective Investigation of Seizure Prophylaxis in Moderate TBI.","authors":"Robert Cortez, Jordan Weinberg, Kristina Kupanoff, Cindy Sullivan, Laura A Snyder, Diane McLaughlin, J Tyler Haller, Sophia S Bonnin","doi":"10.1002/wjs.70505","DOIUrl":"10.1002/wjs.70505","url":null,"abstract":"<p><strong>Background: </strong>Post-traumatic seizures have been shown to occur in patients with traumatic brain injury (TBI). In cases of mild or moderate TBI there is a lack of evidence to guide the use of seizure prophylaxis. The purpose of this study is to characterize seizure rates among patients with mild and moderate TBI with intracranial hemorrhage (ICH) on computed tomography (CT), and to generate hypotheses regarding the potential role of seizure prophylaxis in this population.</p><p><strong>Methods: </strong>This retrospective descriptive study included patients from a large Level I Trauma Center who were admitted with TBI between January 2019 and August 2021. Adult patients included were admitted with a diagnosis of mild or moderate TBI defined as a Glasgow Coma Scale (GCS) score of 9 or above with intracranial hemorrhage (ICH) on CT. The primary outcome was the incidence of suspected seizures or confirmed seizures within the first 7 days of injury.</p><p><strong>Results: </strong>A total of 543 patients were included. 66.9% of patients were male with a mean age of 63 years. Mild TBI was predominantly represented (91.5%) with blunt trauma as the most common mechanism of injury (98.9%). Subdural hematomas were present in 64.8% of patients and subarachnoid hemorrhage in 53%. 41.4% of patients reported a history of alcohol use. Seizures were suspected in 6.2% of patients with mild TBI and confirmed in 3.6%. In moderate TBI, seizures were suspected in 23.9% and confirmed in 15.2%.</p><p><strong>Conclusion: </strong>These findings suggest a high seizure burden in moderate TBI (GCS 9-12) with ICH compared to mild TBI (GCS 13-15) with ICH, and support the need for prospective, risk-stratified trials to evaluate seizure prophylaxis in moderate TBI.</p>","PeriodicalId":23926,"journal":{"name":"World Journal of Surgery","volume":" ","pages":"2734-2740"},"PeriodicalIF":2.2,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13576535/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148473089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Artificial Intelligence in Medical Writing: A Practical and Ethical Framework for Surgical Research and Publication.","authors":"S R Thomson, B A Bassett, J E J Krige","doi":"10.1002/wjs.70504","DOIUrl":"10.1002/wjs.70504","url":null,"abstract":"<p><strong>Background: </strong>Artificial intelligence (AI) is rapidly transforming surgical research and medical publishing by changing how clinicians discover, evaluate, synthesize, and communicate scientific evidence. Despite widespread adoption, practical guidance on the responsible integration of AI into academic writing remains limited, particularly as large language models (LLMs) and emerging AI systems become increasingly sophisticated.</p><p><strong>Methods: </strong>This narrative review examines the contemporary AI ecosystem relevant to medical writing, including LLMs, retrieval-augmented systems, structured evidence extraction platforms, citation analytics tools, AI-enhanced academic databases, and emerging agentic AI systems. Current evidence relating to AI-assisted manuscript preparation, ethical considerations, governance, confidentiality, reproducibility, and scientific integrity was reviewed. A practical workflow integrating literature discovery, evidence extraction, synthesis, citation validation, and editorial refinement is proposed.</p><p><strong>Results: </strong>AI can substantially improve the efficiency, organization, clarity, and consistency of manuscript preparation while supporting evidence retrieval, synthesis, and editorial refinement. However, responsible use requires awareness of important limitations, including hallucinated references, publication bias amplification, confidentiality risks, language weighting, and the inability of current LLMs to distinguish reliably between truth and plausibility. The review also highlights the increasing integration of academic databases with AI-assisted retrieval and synthesis, together with the emergence of agentic research systems capable of performing increasingly complex scientific workflows under human supervision.</p><p><strong>Conclusions: </strong>AI should be regarded as an adjunct to, not a substitute for, scientific reasoning and scholarly judgment. When used transparently and under expert supervision, AI can enhance the quality and efficiency of medical writing while preserving the central intellectual responsibilities of authorship, interpretation, verification, and accountability. As AI systems become increasingly autonomous, maintaining rigorous human oversight will become progressively more important.</p>","PeriodicalId":23926,"journal":{"name":"World Journal of Surgery","volume":" ","pages":"2625-2632"},"PeriodicalIF":2.2,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13576536/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148438193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of a Surgical Data Availability and Transferability Assessment Tool and Its Use in Evaluating Mozambique's Surgical Data Ecosystem.","authors":"Isménia Simbine, Greta L Davis, Emilia V Noormahomed, Chadreque Muluana, Edson Francisco, Stephen W Bickler, Matchecane Cossa, John Rose","doi":"10.1002/wjs.70507","DOIUrl":"10.1002/wjs.70507","url":null,"abstract":"<p><strong>Background: </strong>In 2015, the Lancet Commission on Global Surgery promoted the adoption of six perioperative care indicators and increased their visibility in national health policies. However, regular reporting of these surgical indicators remains limited due to challenges with data infrastructure and workforce capacity. This study defines the surgical data ecosystem in a low-income country and develops a tool for harmonizing national data ecosystems with validated global indicators.</p><p><strong>Methods: </strong>This exploratory, mixed-methods study examined the scope of Mozambique's surgical data ecosystem in 2023. Data were obtained in three phases: qualitative interviews with health data stakeholders, analysis of data instruments from four purposively selected public hospitals, and review of aggregate Ministry of Health reports used for surgical system monitoring and evaluation. These data were organized by domains and compared with international reporting standards, informing development of the Surgical Data Availability and Transferability Assessment (S-DATA) tool for evaluating surgical data availability, transferability, and usability for global benchmarking.</p><p><strong>Results: </strong>Metadata and data instruments were inconsistent across hospitals, which carried into aggregate reports. Facility-level data elements and national reports did not align with national and international guidelines, respectively. Processes for aggregating data varied between data managers, leading to loss of information in summary reports. The flow of surgical data from facility to national reports revealed multiple parallel data streams. These findings informed development and pilot application of the S-DATA tool, with variable data ecosystem performance at the facility level, ranging from fair to poor, yet excellent metadata availability at the highest levels of aggregation.</p><p><strong>Conclusions: </strong>This study represents the first structured evaluation of a surgical data ecosystem in Mozambique and the development of a novel framework for benchmarking surgical data availability against international standards. Data management analysis revealed gaps, redundancies, and inefficiencies at each level of aggregation. Standardized data instruments and reporting processes may facilitate monitoring and evaluation of surgical systems. Future studies are necessary to validate the S-DATA tool in additional settings.</p>","PeriodicalId":23926,"journal":{"name":"World Journal of Surgery","volume":" ","pages":"2680-2691"},"PeriodicalIF":2.2,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13576621/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148680026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Consultant-Delivered Emergency Laparotomy and the Disappearing Training Opportunity: A Missing Metric in NELA.","authors":"Stavros Gourgiotis, Fanourios Georgiades","doi":"10.1002/wjs.70511","DOIUrl":"10.1002/wjs.70511","url":null,"abstract":"","PeriodicalId":23926,"journal":{"name":"World Journal of Surgery","volume":" ","pages":"2522-2524"},"PeriodicalIF":2.2,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13576588/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148563182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predicting Structural Progression-Free Survival After Surgery for Medullary Thyroid Carcinoma.","authors":"I Ros-Madrid, B Febrero, R P Cano-Mármol, P Segura, M Ferrer, J M Rodríguez","doi":"10.1002/wjs.70524","DOIUrl":"10.1002/wjs.70524","url":null,"abstract":"<p><strong>Introduction: </strong>Medullary thyroid cancer (MTC) is an aggressive tumor for which surgery is the only curative treatment. However, after surgery, some patients may experience persistence/recurrence. It is important to identify the prognostic factors that may affect structural disease-free survival (SDFS), which may influence the follow-up of our patients.</p><p><strong>Objective: </strong>To assess SDFS in patients with MTC and related factors.</p><p><strong>Methods: </strong>A retrospective observational study was conducted in a tertiary hospital including patients with MTC without distant metastases. The following variables were assessed: sex, age, heritability, type of surgery, calcitonin (Ct) and CEA, tumor size, stage, lymph nodes ratio (LNR), vascular invasion, high risk, structural disease, and SDFS. A descriptive and comparative univariate and multivariate analysis of SDFS was performed using SPSS version.29 and Cox regression, defining structural disease as the event. p < 0.05 was considered statistically significant.</p><p><strong>Results: </strong>A total of 140 patients with a median age of 34 years were evaluated. Forty-six percent (n = 65) were male. Twenty-two percent (n = 31) had sporadic MTC, 75% (n = 106) had MEN2a, and 2% (n = 3) had MEN2b. The median calcitonin level was 182.5pg/mL and median follow-up was 179.5 months. Structural disease occurred in 24% of patients (n = 33). The variables that influenced the SDFS were as follows: sporadic CMT, older age, preoperative CEA, size, lymph node involvement, higher LNR, vascular invasion and high risk, and Ct levels > 150pg/mL at 6-12 months. In the multivariate analysis, age, LNR, T category, and postoperative Ct remained independent predictors.</p><p><strong>Conclusion: </strong>The SDFS in MTC is significantly influenced by LNR, T category, and postoperative Ct levels at 6-12 months.</p>","PeriodicalId":23926,"journal":{"name":"World Journal of Surgery","volume":" ","pages":"2662-2668"},"PeriodicalIF":2.2,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13576601/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148697481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Impact of Prehabilitation on Clinical Outcomes in Liver Surgery: A Systematic Review and Meta-Analysis.","authors":"Lyrics M Noba, Robyn J Stiger, Declan F J Dunne, Lawrence D Hayes, Christopher J Gaffney, Ramani S Moonesinghe, Ewen M Harrison","doi":"10.1002/wjs.70501","DOIUrl":"10.1002/wjs.70501","url":null,"abstract":"<p><strong>Background: </strong>Major liver surgery is associated with significant physiological stress and a high rate of postoperative complications. Prehabilitation aims to enhance physiological reserve before surgery. Despite the growing volume of liver resections worldwide, the impact of prehabilitation on clinical and economic outcomes in patients undergoing elective liver resection is poorly understood.</p><p><strong>Methods: </strong>A systematic review and meta-analysis was reported in accordance with PRISMA guidelines. MEDLINE, Embase, Web of Science and the Cochrane Library were searched in November 2025. Randomized controlled trials and comparative observational studies evaluating preoperative programs with a structured exercise component, with or without additional nutritional and psychological support in adult patients undergoing major elective liver surgery were included.</p><p><strong>Results: </strong>Six studies (four RCTs and two comparative cohort studies) comprising 557 patients were included. Prehabilitation resulted in significantly fewer overall postoperative complications (OR 0.55; 95% CI, 0.37 to 0.84; p = 0.005). No significant differences were observed for length of stay (MD -0.38 days; 95% CI, -1.08 to 0.32; p = 0.29), major complications (OR 0.79; 95% CI, 0.50 to 1.27; p = 0.33), mortality (OR 0.40; 95% CI, 0.05 to 3.24; p = 0.39), readmission (OR 0.85; 95% CI, 0.47 to 1.55; p = 0.60) and hospitalization costs (MD = -137.13; 95% CI, -642.19, 367.93; p = 0.59).</p><p><strong>Conclusion: </strong>Prehabilitation significantly reduces overall postoperative complications following liver resection. The absence of standardized, liver-specific interventions limits the determination of effective program design. Future research should prioritize standardised protocols and evaluate post-hepatectomy functional recovery, patient-reported outcomes and cost-effectiveness.</p>","PeriodicalId":23926,"journal":{"name":"World Journal of Surgery","volume":" ","pages":"2704-2713"},"PeriodicalIF":2.2,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13576545/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148520999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From Barriers to Solutions: Establishing an Academic Pediatric Surgical Hub in an Underserved Region of Tunisia.","authors":"Saida Hidouri, Saida Sakhri, Yosra Elmansouri, Najla Feriani, Sabrine Ben Ammar","doi":"10.1002/wjs.70514","DOIUrl":"10.1002/wjs.70514","url":null,"abstract":"<p><p>In low- and middle-income countries (LMIC), pediatric surgical care remains concentrated in urban tertiary centers, resulting in delayed access for rural populations. To address this inequity, we established an academic pediatric surgery department within a secondary-level regional hospital in Zaghouan, Tunisia, serving a broad underserved catchment area. Operating without dedicated pediatric infrastructure or pediatric anesthesiology services, we implemented a \"service without walls\" model by embedding pediatric surgery within an existing adult surgical department. Adult wards and perioperative systems were adapted through close collaboration with anesthesia teams, and a strict triage system was implemented to ensure safe case selection. Since its establishment, the department has demonstrated a significant increase in activity, with an 84% rise in annual surgical volume (361 procedures in 2025) and a tripling of inpatient admissions. The service now manages a wide spectrum of pediatric surgical conditions locally, including emergencies and selected complex cases, while high-risk neonates are stabilized and referred. No perioperative mortality occurred, and postoperative morbidity was limited to 3% consisting of minor wound-related complications. Our experience demonstrates that establishing a regional surgical hub does not require waiting for flawless infrastructure. By embedding pediatric surgery within existing adult surgical infrastructure, implementing collaborative perioperative protocols, and using triage-based risk management, safe pediatric surgical care can be successfully decentralized in resource-constrained settings. This model provides a scalable framework for improving access to pediatric surgical care in similar LMIC settings.</p>","PeriodicalId":23926,"journal":{"name":"World Journal of Surgery","volume":" ","pages":"2699-2703"},"PeriodicalIF":2.2,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13576565/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148670504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Impact of Unmeasured Venous Thromboembolism Prophylaxis on the Association Between Hypocalcemia and Pulmonary Embolism.","authors":"Shitang Xu","doi":"10.1002/wjs.70509","DOIUrl":"10.1002/wjs.70509","url":null,"abstract":"","PeriodicalId":23926,"journal":{"name":"World Journal of Surgery","volume":" ","pages":"2760-2761"},"PeriodicalIF":2.2,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13576579/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148563135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reoperation Versus Self-Reported Recurrence After Ventral Hernia Repair: A Nationwide Survey- and Register-Based Study.","authors":"Evy Á Lakjuni Guttesen, Hugin Reistrup, Anders Gram-Hanssen, Jacob Rosenberg, Jason Joe Baker","doi":"10.1002/wjs.70512","DOIUrl":"10.1002/wjs.70512","url":null,"abstract":"<p><strong>Background: </strong>Reoperation is often used as an outcome measure after ventral hernia repair but may underestimate the true recurrence rate, potentially leading to biased interpretation of studies using reoperation for recurrence as an outcome. This study aimed to determine the proportion of patients with recurrence after ventral hernia repair who undergo reoperation for recurrence in a nationwide population.</p><p><strong>Methods: </strong>This nationwide survey- and register-based study, part of the AFTERHERNIA Project, included patients ≥ 18 years undergoing primary ventral or incisional hernia repair between January 2014 and March 2024. Patients were identified in the Danish National Patient Register and invited to participate in an electronic survey. Survey responses were linked to the Danish Ventral Hernia Database. Recurrence was defined as either reoperation for recurrence or self-reported recurrence. Prevalences were estimated and adjusted for using regression analyses with marginal standardization.</p><p><strong>Results: </strong>A total of 20,703 patients were included (16,904 primary ventral and 3799 incisional hernias; 80% response rate), with a median follow-up of 5.5 years. Among primary ventral hernias, overall recurrence was 15.5% (95% CI, 15.0-16.1), of which 3.3% (95% CI, 3.1-3.6) had a reoperation and 12.2% (95% CI, 11.7-12.7) had self-reported recurrence. Among incisional hernias, overall recurrence was 27.2% (95% CI, 25.8-28.6), of which 7.0% (95% CI, 6.3-7.7) had a reoperation and 20.2% (95% CI, 18.9-21.5) had self-reported recurrence.</p><p><strong>Conclusion: </strong>The prevalence of reoperation for recurrence underestimated the overall prevalence of recurrence by approximately fivefold after primary ventral hernia repair and fourfold after incisional hernia repair.</p>","PeriodicalId":23926,"journal":{"name":"World Journal of Surgery","volume":" ","pages":"2600-2608"},"PeriodicalIF":2.2,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13576578/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148608044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}