Zentralblatt fur Gynakologie最新文献

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Different T-cell receptor (TCR) zeta chain expression in cervical cancer and its precursor lesions. 不同t细胞受体(TCR) zeta链在宫颈癌及其前驱病变中的表达。
Zentralblatt fur Gynakologie Pub Date : 2006-10-01 DOI: 10.1055/s-2006-933423
I Zehbe, M Schmidt, M Maeurer, C Leo, M Höckel, H Pilch
{"title":"Different T-cell receptor (TCR) zeta chain expression in cervical cancer and its precursor lesions.","authors":"I Zehbe,&nbsp;M Schmidt,&nbsp;M Maeurer,&nbsp;C Leo,&nbsp;M Höckel,&nbsp;H Pilch","doi":"10.1055/s-2006-933423","DOIUrl":"https://doi.org/10.1055/s-2006-933423","url":null,"abstract":"<p><strong>Objective: </strong>Cervical cancer is associated with infection of epithelial cells with the human papillomavirus (HPV) type 16 and HPV18. A functional signalling machinery in T-cells is required in order to successfully fight and eradicate HPV16+ transformed epithelial cells. One of the key signalling molecules associated with the T-cell receptor (TCR) is the homodimeric zeta chain molecule.</p><p><strong>Material and methods: </strong>28 formalin fixed und paraffin embedded samples of cervical tissue with cervical intraepithelial lesions CIN I (n = 3), CIN III (n = 7), invasive cervical carcinoma (CC) (n = 13) and normal cervical tissue (n = 5) has been evaluated for HPV-PCR und zeta chain immunohistochemistry. For immunohistochemistry a monoclonal IgG1 anti TZR zeta chain-antibody (mAb) has been used (clone 6B 10.2, Santa Cruz, Heidelberg, Germany). According to the performed Western-Blot analysis on peripheral blood monocytes (PBMCs) the used mAb has specifically recognized TCR zeta chains.</p><p><strong>Results: </strong>We show reduced protein zeta chain expression associated with invasive cervical cancer, but not with pre-invasive HPV16-positive lesions or HPV16-negative normal cervix tissue.</p><p><strong>Conclusions: </strong>Thus, reduced TCR zeta chain expression is not necessarily linked to a chronic viral infection, nor to the presence of transformed cells, but rather to the stromal invasion of the cancer lesion.</p>","PeriodicalId":23881,"journal":{"name":"Zentralblatt fur Gynakologie","volume":"128 5","pages":"266-70"},"PeriodicalIF":0.0,"publicationDate":"2006-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1055/s-2006-933423","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26331375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
Audiovisuelle Narkoseaufklärung in der Geburtshilfe 视听麻醉术
Zentralblatt fur Gynakologie Pub Date : 2006-08-22 DOI: 10.1055/S-2006-950550
T. Laux, C. Madler
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引用次数: 2
Wo sind die Fortschritte in der gynäkologischen Onkologie 妇科肿瘤学的进展呢
Zentralblatt fur Gynakologie Pub Date : 2006-08-22 DOI: 10.1055/S-2006-950567
M. Kaufmann
{"title":"Wo sind die Fortschritte in der gynäkologischen Onkologie","authors":"M. Kaufmann","doi":"10.1055/S-2006-950567","DOIUrl":"https://doi.org/10.1055/S-2006-950567","url":null,"abstract":"","PeriodicalId":23881,"journal":{"name":"Zentralblatt fur Gynakologie","volume":"58 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2006-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80236554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Der Einfluss maternalen Alters auf die Assoziation eines isolierten fetalen intrakardialen echogenen Fokus mit einer chromosomalen Aberration 用基因文本让位于位于偏僻的胎儿心脏检查结果的影响
Zentralblatt fur Gynakologie Pub Date : 2006-08-22 DOI: 10.1055/S-2006-950544
A. Puhl, C. Interthal, C. Lindner, V. Passuello, D. Macchiella, E. Steiner, H. Kölbl
{"title":"Der Einfluss maternalen Alters auf die Assoziation eines isolierten fetalen intrakardialen echogenen Fokus mit einer chromosomalen Aberration","authors":"A. Puhl, C. Interthal, C. Lindner, V. Passuello, D. Macchiella, E. Steiner, H. Kölbl","doi":"10.1055/S-2006-950544","DOIUrl":"https://doi.org/10.1055/S-2006-950544","url":null,"abstract":"","PeriodicalId":23881,"journal":{"name":"Zentralblatt fur Gynakologie","volume":"88 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2006-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85596219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Das Mammastammzellkonzept – ein theoretisches Konstrukt oder klinisch bedeutsam? 马方细胞概念是理论意义还是临床意义?
Zentralblatt fur Gynakologie Pub Date : 2006-08-22 DOI: 10.1055/S-2006-950561
A. Rody, U. Holtrich, C. Solbach, V. Müller, E. Ruckhäberle, R. Gätje, M. Gehrmann, G. Minckwitz, T. Karn, M. Kaufmann
{"title":"Das Mammastammzellkonzept – ein theoretisches Konstrukt oder klinisch bedeutsam?","authors":"A. Rody, U. Holtrich, C. Solbach, V. Müller, E. Ruckhäberle, R. Gätje, M. Gehrmann, G. Minckwitz, T. Karn, M. Kaufmann","doi":"10.1055/S-2006-950561","DOIUrl":"https://doi.org/10.1055/S-2006-950561","url":null,"abstract":"","PeriodicalId":23881,"journal":{"name":"Zentralblatt fur Gynakologie","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2006-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76366780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Wieviel Zurückhaltung ist geboten beim Einsatz transvaginaler Netze? Überlegungen zur Indikationsstellung innovativer Methoden 外阴网的使用,需要做多少克制?这都要考虑到过去的学习技巧
Zentralblatt fur Gynakologie Pub Date : 2006-08-22 DOI: 10.1055/S-2006-950519
W. Adelhardt
{"title":"Wieviel Zurückhaltung ist geboten beim Einsatz transvaginaler Netze? Überlegungen zur Indikationsstellung innovativer Methoden","authors":"W. Adelhardt","doi":"10.1055/S-2006-950519","DOIUrl":"https://doi.org/10.1055/S-2006-950519","url":null,"abstract":"","PeriodicalId":23881,"journal":{"name":"Zentralblatt fur Gynakologie","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2006-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83606559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Problematik der Verwahrlosung – „Frühe Hilfen“ 浪费“早期援助”问题
Zentralblatt fur Gynakologie Pub Date : 2006-08-22 DOI: 10.1055/S-2006-950531
J. Möller
{"title":"Problematik der Verwahrlosung – „Frühe Hilfen“","authors":"J. Möller","doi":"10.1055/S-2006-950531","DOIUrl":"https://doi.org/10.1055/S-2006-950531","url":null,"abstract":"","PeriodicalId":23881,"journal":{"name":"Zentralblatt fur Gynakologie","volume":"36 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2006-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78421810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Optimierte Geburt – zwischen Risikominderung und Wunscherfüllung 乐观的分娩——在减少风险和实现愿望之间
Zentralblatt fur Gynakologie Pub Date : 2006-08-22 DOI: 10.1055/S-2006-950530
C. Brezinka
{"title":"Optimierte Geburt – zwischen Risikominderung und Wunscherfüllung","authors":"C. Brezinka","doi":"10.1055/S-2006-950530","DOIUrl":"https://doi.org/10.1055/S-2006-950530","url":null,"abstract":"","PeriodicalId":23881,"journal":{"name":"Zentralblatt fur Gynakologie","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2006-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78440785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Audiovisuelle Narkoseaufklärung in der operativen Gynäkologie 视听麻醉学妇科教育
Zentralblatt fur Gynakologie Pub Date : 2006-08-22 DOI: 10.1055/S-2006-950569
T. Laux, C. Madler
{"title":"Audiovisuelle Narkoseaufklärung in der operativen Gynäkologie","authors":"T. Laux, C. Madler","doi":"10.1055/S-2006-950569","DOIUrl":"https://doi.org/10.1055/S-2006-950569","url":null,"abstract":"","PeriodicalId":23881,"journal":{"name":"Zentralblatt fur Gynakologie","volume":"104 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2006-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85785600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Intraoperative Strahlentherapie des Mammakarzinoms – Derzeitiger Stellenwert 这是放射性物质
Zentralblatt fur Gynakologie Pub Date : 2006-08-22 DOI: 10.1055/S-2006-950564
F. Melchert, L. Bauer, U. Kraus-Tiefenbacher, F. Wenz
{"title":"Intraoperative Strahlentherapie des Mammakarzinoms – Derzeitiger Stellenwert","authors":"F. Melchert, L. Bauer, U. Kraus-Tiefenbacher, F. Wenz","doi":"10.1055/S-2006-950564","DOIUrl":"https://doi.org/10.1055/S-2006-950564","url":null,"abstract":"","PeriodicalId":23881,"journal":{"name":"Zentralblatt fur Gynakologie","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2006-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79936589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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