Norbert Skokauskas,Gary Chaimowitz,Dina Aly El-Gabry,Andrea Fiorillo,Anusha Lachman,Angeles Lopez Geist,Paul Robertson,Hee Jeong Yoo,Bennett L Leventhal
{"title":"Advancing global mental health through education.","authors":"Norbert Skokauskas,Gary Chaimowitz,Dina Aly El-Gabry,Andrea Fiorillo,Anusha Lachman,Angeles Lopez Geist,Paul Robertson,Hee Jeong Yoo,Bennett L Leventhal","doi":"10.1002/wps.21368","DOIUrl":"https://doi.org/10.1002/wps.21368","url":null,"abstract":"","PeriodicalId":23858,"journal":{"name":"World Psychiatry","volume":"3 1","pages":"453-454"},"PeriodicalIF":73.3,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145059167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mariana Pinto da Costa,Tommaso Squeri,Lucía Péréz Gómez,Bernardo Flôr-Rodrigues
{"title":"Patient involvement in undergraduate psychiatric education: an international survey.","authors":"Mariana Pinto da Costa,Tommaso Squeri,Lucía Péréz Gómez,Bernardo Flôr-Rodrigues","doi":"10.1002/wps.21372","DOIUrl":"https://doi.org/10.1002/wps.21372","url":null,"abstract":"","PeriodicalId":23858,"journal":{"name":"World Psychiatry","volume":"3 1","pages":"459-460"},"PeriodicalIF":73.3,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145059178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Promoting collaboration, harmonization and dissemination in depression research: the ECNP Depression Meta-Network.","authors":"Andreas Reif, ,Brenda W J H Penninx","doi":"10.1002/wps.21366","DOIUrl":"https://doi.org/10.1002/wps.21366","url":null,"abstract":"","PeriodicalId":23858,"journal":{"name":"World Psychiatry","volume":"45 1","pages":"450-451"},"PeriodicalIF":73.3,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145059185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Christoph U Correll,Samuele Cortese,Marco Solmi,Tommaso Boldrini,Koen Demyttenaere,Katharina Domschke,Paolo Fusar-Poli,Philip Gorwood,Philip D Harvey,Richard S E Keefe,Christine Knaevelsrud,Roman Kotov,Laura Nohr,Taeho Greg Rhee,David Roe,Matthias Rose,Lon S Schneider,Mike Slade,Dan J Stein,Charlene Sunkel,Roger S McIntyre
{"title":"Beyond symptom improvement: transdiagnostic and disorder-specific ways to assess functional and quality of life outcomes across mental disorders in adults.","authors":"Christoph U Correll,Samuele Cortese,Marco Solmi,Tommaso Boldrini,Koen Demyttenaere,Katharina Domschke,Paolo Fusar-Poli,Philip Gorwood,Philip D Harvey,Richard S E Keefe,Christine Knaevelsrud,Roman Kotov,Laura Nohr,Taeho Greg Rhee,David Roe,Matthias Rose,Lon S Schneider,Mike Slade,Dan J Stein,Charlene Sunkel,Roger S McIntyre","doi":"10.1002/wps.21338","DOIUrl":"https://doi.org/10.1002/wps.21338","url":null,"abstract":"Improving meaningful outcomes is the main goal of clinical care for mental disorders. Traditionally, the focus in clinical research and practice has been on outcome domains that refer to symptom severity or service use (e.g., hospitalization), relate to categorical diagnoses, and favour clinician-rated measures. More recently, self-rated and dimensional as well as transdiagnostic outcome domains have gained traction, and functioning, quality of life and well-being/life satisfaction, along with the construct of personal recovery, have become a stronger focus. These key multidimensional outcome domains need to be properly defined and assessed. Further, the concepts of \"functional\" and \"personal\" recovery need to be differentiated. \"Functional recovery\" is defined by observed functioning across the domains of self-care, social interactions, leisure time activities, and educational or vocational activities. \"Personal recovery\" involves the subjective sense of living a personally meaningful life, irrespective of whether symptoms continue, or ongoing/intermittent support is needed. Despite the multi-stakeholder relevance of these outcome domains, no comprehensive account of how to measure them is available. To fill this gap, we provide here an overview of the main tools to assess functioning, quality of life/well-being/life satisfaction, and personal recovery outcomes across mental disorders in adults, aiming to also identify additional needs that should be addressed. We identified tools that can be used in clinical and research practice to assess people with the following mental health conditions: anxiety disorders, bipolar disorder, dementias, eating disorders, major depressive disorder, obsessive-compulsive and related disorders, personality disorders, post-traumatic stress disorder, schizophrenia, and substance use disorders. Both transdiagnostic and disorder-specific measures are described. Suggested tools were selected keeping feasibility and scalability needs in mind. The incorporation of these measures in both research and clinical care will enrich patient assessment as well as treatment planning and evaluation, increasing the likelihood of enhanced outcomes in people living with mental disorders.","PeriodicalId":23858,"journal":{"name":"World Psychiatry","volume":"56 1","pages":"296-318"},"PeriodicalIF":73.3,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145059091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Joe Kwun Nam Chan,Marco Solmi,Heidi Ka Ying Lo,Michelle Wai Yan Chan,Leo Long Tin Choo,Eric Tsz Him Lai,Corine Sau Man Wong,Christoph U Correll,Wing Chung Chang
{"title":"All-cause and cause-specific mortality in people with depression: a large-scale systematic review and meta-analysis of relative risk and aggravating or attenuating factors, including antidepressant treatment.","authors":"Joe Kwun Nam Chan,Marco Solmi,Heidi Ka Ying Lo,Michelle Wai Yan Chan,Leo Long Tin Choo,Eric Tsz Him Lai,Corine Sau Man Wong,Christoph U Correll,Wing Chung Chang","doi":"10.1002/wps.21354","DOIUrl":"https://doi.org/10.1002/wps.21354","url":null,"abstract":"Depression has been reported to be associated with premature mortality. However, no meta-analysis has comprehensively examined all-cause and cause-specific mortality risk in people with this condition, focusing also on possible aggravating and attenuating factors, including antidepressant treatment. We conducted a systematic review and meta-analysis of cohort studies to synthesize mortality risk estimates associated with depression (major depressive disorder and dysthymia) due to any and specific causes, and when depression is accompanied by comorbid conditions. Effects of antidepressant medication and electroconvulsive therapy (ECT), and other potential moderators of mortality risk, were evaluated. We searched EMBASE, Medline and PsycINFO databases up to January 26, 2025, pooling mortality estimates using random-effect models. Publication bias, subgroup and meta-regression analyses, and quality assessment (Newcastle-Ottawa Scale) were performed. Across 268 studies, 10,842,094 individuals with depression and 2,837,933,536 control subjects were included. All-cause mortality was doubled in people with depression versus no depression/general population controls (relative risk, RR=2.10, 95% CI: 1.87-2.35, I2=99.9%), being especially high for suicide (RR=9.89, 95% CI: 7.59-12.88, I2=99.6%), but also elevated for natural causes (RR=1.63, 95% CI: 1.51-1.75, I2=99.6%). Among individuals with versus without depression matched for comorbid conditions, the depression-associated mortality risk was also significantly elevated (RR=1.29, 95% CI: 1.21-1.37, I2=99.9%). Depression with versus without psychotic symptoms (RR=1.61, 95% CI: 1.45-1.78, I2=6.3%), and treatment-resistant versus non-treatment-resistant depression (RR=1.27, 95% CI: 1.16-1.39, I2=85.3%), conferred an incremental mortality risk. Antidepressant use (versus no antidepressant use) was associated with significantly lower all-cause mortality in people with depression (RR=0.79, 95% CI: 0.68-0.93, I2=99.2%). ECT use (versus no ECT use) was associated with reduced all-cause mortality (RR=0.73, 95% CI: 0.66-0.82, I2=0%), natural-cause mortality (RR=0.76, 95% CI: 0.59-0.97, I2=12.0%), and suicide (RR=0.67, 95% CI: 0.53-0.85, I2=32.3%). Our results affirm heightened mortality risk in depression, identify clinically relevant patient subgroups with increased mortality risk, and highlight mortality-reducing effects of antidepressant treatment and ECT. Multipronged intervention approaches targeting physical health improvement and suicide risk alleviation, optimizing antidepressant treatment, and pursuing early identification and effective interventions for psychotic and treatment-resistant depression, could help reduce this mortality gap, which is still growing.","PeriodicalId":23858,"journal":{"name":"World Psychiatry","volume":"45 1","pages":"404-421"},"PeriodicalIF":73.3,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145059137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marina Letica-Crepulja,Georgios Pagkalos,Joshua C Morganstein,Kristina Adorjan,Malcolm Hopwood
{"title":"Report from the WPA Section on Military Psychiatry.","authors":"Marina Letica-Crepulja,Georgios Pagkalos,Joshua C Morganstein,Kristina Adorjan,Malcolm Hopwood","doi":"10.1002/wps.21373","DOIUrl":"https://doi.org/10.1002/wps.21373","url":null,"abstract":"","PeriodicalId":23858,"journal":{"name":"World Psychiatry","volume":"36 1","pages":"458-459"},"PeriodicalIF":73.3,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145059156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Colin D Freilich,Frank D Mann,Kristian E Markon,Steve W Cole,Robert F Krueger
{"title":"Predicting epigenetic aging by the transdiagnostic internalizing spectrum vs. depressive and anxiety syndromes.","authors":"Colin D Freilich,Frank D Mann,Kristian E Markon,Steve W Cole,Robert F Krueger","doi":"10.1002/wps.21364","DOIUrl":"https://doi.org/10.1002/wps.21364","url":null,"abstract":"","PeriodicalId":23858,"journal":{"name":"World Psychiatry","volume":"45 1","pages":"448-450"},"PeriodicalIF":73.3,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145059157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The role of case formulation in the current practice of psychotherapy.","authors":"Tracy D Eells","doi":"10.1002/wps.21341","DOIUrl":"https://doi.org/10.1002/wps.21341","url":null,"abstract":"","PeriodicalId":23858,"journal":{"name":"World Psychiatry","volume":"67 1","pages":"342-343"},"PeriodicalIF":73.3,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145059138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}