Thomas Seufferlein, Julia Mayerle, Stefan Boeck, Thomas Brunner, Thomas J Ettrich, Lars Grenacher, Thomas Mathias Gress, Thilo Hackert, Volker Heinemann, Angelika Kestler, Marianne Sinn, Andrea Tannapfel, Ulrich Wedding, Waldemar Uhl
{"title":"S3-Leitlinie Exokrines Pankreaskarzinom – Version 3.1.","authors":"Thomas Seufferlein, Julia Mayerle, Stefan Boeck, Thomas Brunner, Thomas J Ettrich, Lars Grenacher, Thomas Mathias Gress, Thilo Hackert, Volker Heinemann, Angelika Kestler, Marianne Sinn, Andrea Tannapfel, Ulrich Wedding, Waldemar Uhl","doi":"10.1055/a-2338-3716","DOIUrl":"10.1055/a-2338-3716","url":null,"abstract":"","PeriodicalId":23853,"journal":{"name":"Zeitschrift fur Gastroenterologie","volume":"62 10","pages":"1724-1785"},"PeriodicalIF":1.4,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142401483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sarah Lange, Christina Baehr, Nur Irem Cakman-Hinrichs, Katharina Cron, Hannah Fengels, Christina Gregor, Katrin Matschenz, Jörg Petersen, Robin Steinfurth, Albrecht Stoehr, Stefan Unger, Maria Gil Mir, Candido Hernández, Marianna Schwenken, Peter Buggisch
{"title":"ReLink strategy in diagnosed-but-untreated hepatitis C-positive patients in Germany: report from a single center.","authors":"Sarah Lange, Christina Baehr, Nur Irem Cakman-Hinrichs, Katharina Cron, Hannah Fengels, Christina Gregor, Katrin Matschenz, Jörg Petersen, Robin Steinfurth, Albrecht Stoehr, Stefan Unger, Maria Gil Mir, Candido Hernández, Marianna Schwenken, Peter Buggisch","doi":"10.1055/a-2349-2767","DOIUrl":"10.1055/a-2349-2767","url":null,"abstract":"<p><strong>Objective: </strong>The ReLink project aims to reintegrate diagnosed-but-untreated hepatitis-C-positive patients into medical care and initiate a therapy.</p><p><strong>Material/methods: </strong>A retrospective search within the practice management system of a single center in Germany identified among 1965 hepatitis-C-positive patients 100 untreated patients with available contact details and meeting all inclusion criteria. Patients were contacted by 2 contact rounds.</p><p><strong>Results: </strong>Out of 100 patients, 64% were male. Most patients (81%) were aged between 30 and 59 years. The patients belonged to high-risk groups for hepatitis C virus infections or had other comorbidities. The majority of patients injected drugs (21%) and/or were currently or had been on substitution therapy (44%); alcohol addiction was also frequent (21%). Out of 25 patients who agreed to an appointment, 10 patients (40%) started therapy and 5 additional patients (20%) agreed to therapy but were not yet able to start or had not yet made a decision. One‑third of patients who agreed to an appointment did not show up.</p><p><strong>Conclusions: </strong>Diagnosed-but-untreated patients are an important subgroup of hepatitis-C-positive patients; their recall to the clinic for direct-acting antiviral therapy is possible. However, inaccurate contact information, unresponsiveness to outreach, and further reluctance to attend doctor appointments limited the overall impact of this program. Regular review of the patients' contact details may facilitate both follow-up and recall.</p>","PeriodicalId":23853,"journal":{"name":"Zeitschrift fur Gastroenterologie","volume":" ","pages":"1701-1707"},"PeriodicalIF":1.4,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11466545/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141627753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mikolaj Walensi, David Albers, Dani Dakkak, Wei Meng, Roland Heesen, Kai Nassenstein, Michal Piotrowski, Iuri Krasniuk, Nikolaos Tsilimparis, Pavlos Drongitis, Johannes N Hoffmann
{"title":"Hemosuccus pancreaticus - Multidisciplinary therapy for a splenic artery aneurysm, ruptured into the pancreatic duct.","authors":"Mikolaj Walensi, David Albers, Dani Dakkak, Wei Meng, Roland Heesen, Kai Nassenstein, Michal Piotrowski, Iuri Krasniuk, Nikolaos Tsilimparis, Pavlos Drongitis, Johannes N Hoffmann","doi":"10.1055/a-2364-4462","DOIUrl":"10.1055/a-2364-4462","url":null,"abstract":"<p><strong>Background: </strong>Numerous conditions may lead to gastrointestinal bleeding (GIB). Compared with common causes, hemosuccus pancreaticus (HP) is a scarce and potentially life-threatening condition.</p><p><strong>Case presentation: </strong>We report the case of a 45-year-old female patient who suffered from hematemesis and subsequent hemorrhagic shock. In repeat esophagogastroduodenoscopies, bleeding from the major duodenal papilla was detected. To stop the acute bleeding, an ERCP was performed, and a plastic stent was inserted into the pancreatic duct (PD). Subsequently, MR and CT scans demonstrated a pseudoaneurysm of the splenic artery (SA) with a fistula to the PD. An interventional therapy approach failed due to a highly twisted course of the SA. Thus, the patient underwent surgery with ligation of the SA. The stent from the PD was removed postoperatively, and the patient recovered well. A histological examination of the SA revealed fibromuscular dysplasia. A lifelong ASA therapy was prescribed, and the patient was discharged on the 14th postoperative day in good condition.</p><p><strong>Conclusion: </strong>The diagnosis and treatment of HP might be impeded due to its multiple causes, ambiguous symptoms, and challenging diagnostic verification. Being a potentially life-threatening condition, the knowledge of this rare entity and the provision of multidisciplinary and multimodal therapy are mandatory for the successful treatment of patients with obscure GIB and proven HP.</p>","PeriodicalId":23853,"journal":{"name":"Zeitschrift fur Gastroenterologie","volume":" ","pages":"1708-1714"},"PeriodicalIF":1.4,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142126847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"S2k guideline Gastroesophageal reflux disease and eosinophilic esophagitis of the German Society of Gastroenterology, Digestive and Metabolic Diseases (DGVS).","authors":"","doi":"10.1055/a-2344-6282","DOIUrl":"10.1055/a-2344-6282","url":null,"abstract":"","PeriodicalId":23853,"journal":{"name":"Zeitschrift fur Gastroenterologie","volume":"62 10","pages":"1786-1852"},"PeriodicalIF":1.4,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142401481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Thomas Seufferlein, Julia Mayerle, Stefan Boeck, Thomas Brunner, Thomas J Ettrich, Lars Grenacher, Thomas Mathias Gress, Thilo Hackert, Volker Heinemann, Angelika Kestler, Marianne Sinn, Andrea Tannapfel, Ulrich Wedding, Waldemar Uhl
{"title":"S3-Leitlinie Exokrines Pankreaskarzinom – Version 3.1.","authors":"Thomas Seufferlein, Julia Mayerle, Stefan Boeck, Thomas Brunner, Thomas J Ettrich, Lars Grenacher, Thomas Mathias Gress, Thilo Hackert, Volker Heinemann, Angelika Kestler, Marianne Sinn, Andrea Tannapfel, Ulrich Wedding, Waldemar Uhl","doi":"10.1055/a-2338-3533","DOIUrl":"10.1055/a-2338-3533","url":null,"abstract":"","PeriodicalId":23853,"journal":{"name":"Zeitschrift fur Gastroenterologie","volume":"62 10","pages":"874-995"},"PeriodicalIF":1.4,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142401482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[\"Tailored therapy\" in a 36 year old female patient with persistent dysphagia].","authors":"Felix Gundling, Christopher Moritz Schad","doi":"10.1055/a-2309-5915","DOIUrl":"10.1055/a-2309-5915","url":null,"abstract":"","PeriodicalId":23853,"journal":{"name":"Zeitschrift fur Gastroenterologie","volume":"62 9","pages":"1369-1370"},"PeriodicalIF":1.4,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142296736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pia Lorenz, Niklas Aehling, Tony Bruns, Wolf Bechstein, Thomas Becker, Thomas Berg, Paul Freudenberger, Christian Trautwein, Lars Klug, Petra Lynen Jansen
{"title":"Leitlinienreport der S2k-Leitlinie Lebertransplantation der Deutschen Gesellschaft für Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten (DGVS) und der Deutschen Gesellschaft für Allgemein und Viszeralchirurgie (DGAV).","authors":"Pia Lorenz, Niklas Aehling, Tony Bruns, Wolf Bechstein, Thomas Becker, Thomas Berg, Paul Freudenberger, Christian Trautwein, Lars Klug, Petra Lynen Jansen","doi":"10.1055/a-2255-7355","DOIUrl":"10.1055/a-2255-7355","url":null,"abstract":"","PeriodicalId":23853,"journal":{"name":"Zeitschrift fur Gastroenterologie","volume":"62 9","pages":"e537-e554"},"PeriodicalIF":1.4,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142296737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Thomas Berg, Niklas F Aehling, Tony Bruns, Martin-Walter Welker, Tobias Weismüller, Jonel Trebicka, Frank Tacke, Pavel Strnad, Martina Sterneck, Utz Settmacher, Daniel Seehofer, Eckart Schott, Andreas Anton Schnitzbauer, Hartmut H Schmidt, Hans J Schlitt, Johann Pratschke, Andreas Pascher, Ulf Neumann, Steffen Manekeller, Frank Lammert, Ingo Klein, Gabriele Kirchner, Markus Guba, Matthias Glanemann, Cornelius Engelmann, Ali E Canbay, Felix Braun, Christoph P Berg, Wolf O Bechstein, Thomas Becker, Christian Trautwein
{"title":"S2k-Leitlinie Lebertransplantation der Deutschen Gesellschaft für Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten (DGVS) und der Deutschen Gesellschaft für Allgemein- und Viszeralchirurgie (DGAV).","authors":"Thomas Berg, Niklas F Aehling, Tony Bruns, Martin-Walter Welker, Tobias Weismüller, Jonel Trebicka, Frank Tacke, Pavel Strnad, Martina Sterneck, Utz Settmacher, Daniel Seehofer, Eckart Schott, Andreas Anton Schnitzbauer, Hartmut H Schmidt, Hans J Schlitt, Johann Pratschke, Andreas Pascher, Ulf Neumann, Steffen Manekeller, Frank Lammert, Ingo Klein, Gabriele Kirchner, Markus Guba, Matthias Glanemann, Cornelius Engelmann, Ali E Canbay, Felix Braun, Christoph P Berg, Wolf O Bechstein, Thomas Becker, Christian Trautwein","doi":"10.1055/a-2255-7246","DOIUrl":"10.1055/a-2255-7246","url":null,"abstract":"","PeriodicalId":23853,"journal":{"name":"Zeitschrift fur Gastroenterologie","volume":"62 9","pages":"1397-1573"},"PeriodicalIF":1.4,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142296739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Carsten Posovszky, Stephan Buderus, Johannes Huebner, Rüdiger Adam, Cihan Papan, Bernd Gruber, Florian Schmid, Kathrin Krohn, Philip Wintermeyer, Reto Schwenke, Jande Laffolie, Ulrichvon Both, Hans-Jörg Epple, Philipp A Reuken, Florian Kipfmüller, Anna-Maria Schneider, Angelika Fruth, Sandra Simon, Anne Schmitt, Almuthe Christina Hauer
{"title":"S2k Leitlinie akute infektiöse Gastroenteritis im Säuglings-, Kindes- und Jugendalter – Update 2024.","authors":"Carsten Posovszky, Stephan Buderus, Johannes Huebner, Rüdiger Adam, Cihan Papan, Bernd Gruber, Florian Schmid, Kathrin Krohn, Philip Wintermeyer, Reto Schwenke, Jande Laffolie, Ulrichvon Both, Hans-Jörg Epple, Philipp A Reuken, Florian Kipfmüller, Anna-Maria Schneider, Angelika Fruth, Sandra Simon, Anne Schmitt, Almuthe Christina Hauer","doi":"10.1055/a-2327-6247","DOIUrl":"10.1055/a-2327-6247","url":null,"abstract":"<p><p>The aim of the interdisciplinary S2k guideline \"Acute infectious gastroenteritis in infants, children and adolescents\" is to summarise the current state of knowledge on the clinical presentation, diagnosis, treatment, prevention and hygiene of acute infectious gastroenteritis, including nosocomial gastrointestinal infections, in infants, children and adolescents on the basis of scientific evidence, to evaluate it by expert consensus and to derive practice-relevant recommendations from it. The guideline provides a corridor for action for frequent decisions. It also serves the purpose of evidence-based further education and training and is thus intended to improve the medical care of children with acute gastroenteritis. In particular, the guideline aims to avoid unnecessary hospitalisation of children with AGE and to take preventive measures to avoid and spread infection.</p>","PeriodicalId":23853,"journal":{"name":"Zeitschrift fur Gastroenterologie","volume":"62 9","pages":"1574-1643"},"PeriodicalIF":1.4,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142296738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Management of gastroparesis care in Germany - a survey by the working group of guiding gastroenterologic clinicians (Arbeitsgemeinschaft Leitender Gastroenterologischer Krankenhausärzte, ALGK)].","authors":"Felix Gundling, Thomas Frieling","doi":"10.1055/a-2350-7432","DOIUrl":"10.1055/a-2350-7432","url":null,"abstract":"<p><strong>Introduction: </strong>The treatment of gastroparesis can be difficult in everyday clinical practice. The aim of this anonymous survey of members of the Arbeitsgemeinschaft Leitender Gastroenterologischer Krankenhausärzte e.V. (ALGK) was to investigate the management of gastroparesis care in Germany.</p><p><strong>Material and methods: </strong>The ALGK conducted a member survey using a standardized anonymous questionnaire including 11 questions from 14.04.2023 to 29.04.2023. The questions covered diagnostic and therapeutic procedures as well as various aspects of the management of gastroparesis.</p><p><strong>Results: </strong>The response rate was 21.4% (62 members). Only 6.56% of all respondents assessed the prevalence of gastroparesis correctly as estimated by current epidemiological publications. 68.85 % of all respondents used gastric emptying scintigraphy for diagnosis. 51.61% regarded an individualized therapy as the most important treatment goal, taking into account etiology and impact of symptoms, compared to symptomatic treatment of leading clinical symptom in 43,55 %. First choice treatment was medical treatment in 41.94%, dietary recommendations in 27.42% and endoscopic interventions in 24.2%. 100% of respondents used prokinetics, 40.32% used antiemetics while only 4.84% used analgesics. Insufficient availability of medical treatment options represents a need of action for 85.48%, compared to lacking official approval of available drugs for this indication for 48,39% of all respondents. Treatment options with little evidence were used quite frequently (e.g. use of herbal therapies in 43.55%).</p><p><strong>Discussion: </strong>Overall, the frequency of gastroparesis was underestimated in the current survey. Endoscopic options are quite often used as first-line treatment. Although symptom-guided treatment is important for the majority of respondents, prokinetics are predominantly used.</p>","PeriodicalId":23853,"journal":{"name":"Zeitschrift fur Gastroenterologie","volume":" ","pages":"1371-1378"},"PeriodicalIF":1.4,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141627752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}