{"title":"Nature of yellow-brown bodies. Histochemical and ultrastructural studies on the brown pigment.","authors":"M Senba, K Kawai","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Yellow-brown bodies were observed in the sinusoids of lymph nodes and in histiocytes. The authors examined their histochemical characteristics. They were similar to lipofuscin pigments in the liver. However, ultrastructurally, yellow-brown bodies were different from lipofuscin and melanin pigments. The electron microscopic investigation suggested that degradation products of yellow-brown bodies in histiocytes resemble brown pigments in the black thyroid.</p>","PeriodicalId":23840,"journal":{"name":"Zentralblatt fur allgemeine Pathologie u. pathologische Anatomie","volume":"135 4","pages":"351-5"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13920104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Role of rhythmic structures of aortic intima in the development of atherosclerosis.","authors":"A M Vikhert, V S Zhdanov","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>517 thoracic and abdominal aortas from newborns and children aged up to 14 years and 606 from males aged 20-39 years were examined. Rhythmic structures (wave lines) were detected in 4.7% of stillborns, but their frequency was found to increase with age. After the first year of life they occurred in 60% and after 20 years in 70%. Their frequency was significantly higher in the abdominal than in the thoracic aorta. Fibrous plaques were found in 39.4% of subjects aged 20-29 years and in 83% of those aged 30-39 years, and in 84% in the area of rhythmic structures. There were all stages of transformation of rhythmic structures into fibrous plaques. The extent of fibrous plaques was significantly higher in aortas with rhythmic structures than in those without. Initial microscopic changes in rhythmic structures involved smooth muscle cell proliferation in the underlying media and disintegration of the internal elastic membrane as well as migration of smooth muscle cells into the intima. The latter cases exhibited formation of an abundant irregular net of elastic and collagenous fibers and stromal edema with fibrin deposition, followed by sclerosis. Fibrous plaques contained no lipids. The latter were occasionally detected in some smooth muscle cells, whereas in subjects over 35 years they were also found extracellularly on the site of destructured foam cells.</p>","PeriodicalId":23840,"journal":{"name":"Zentralblatt fur allgemeine Pathologie u. pathologische Anatomie","volume":"135 6","pages":"607-17"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13953576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L Danihel, M Zaviacic, P Janík, J Porubský, P Babál, V Nagy
{"title":"[Myocardial damage as a rare complication of mucoviscidosis].","authors":"L Danihel, M Zaviacic, P Janík, J Porubský, P Babál, V Nagy","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A postmortem examination was performed on a male child who had lived to twelve months of age, at the Institute of Pathology of the Medical Faculty of Comenius University in Bratislava, Czechoslovakia. The clinical diagnosis had been mucoviscidosis, bronchopneumonia, and dystrophy. Findings characteristic of cystic pancreas fibrosis and bronchopneumonia of the right lower lung lobe were macroscopically recorded and were microscopically established. Massive fibrotic and necrotic lesions were primarily recorded from the left cardiac ventricle and were considered to be unusual findings. Damage to the myocardium is a very rare complication of mucoviscidosis. Less than 50 cases have so far been described, according to Benesová et al. (1983).</p>","PeriodicalId":23840,"journal":{"name":"Zentralblatt fur allgemeine Pathologie u. pathologische Anatomie","volume":"135 5","pages":"457-61"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13955195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Craniopharyngioma in a fetus].","authors":"W Jänisch, H G Flegel","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Intrauterine sonography reveals pathological enlargement of the head and an abnormal intracranial mass in a fetus (25th week of gestation). Birth induction results in a stillborn female child (weight 1,590 g; length 35 cm; head circumference 32 cm). The supratentorial space is almost totally occupied by a craniopharyngioma, measuring 8 cm in diameter.</p>","PeriodicalId":23840,"journal":{"name":"Zentralblatt fur allgemeine Pathologie u. pathologische Anatomie","volume":"135 1","pages":"65-9"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14065579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Histomorphologic and catamnestic studies of 226 patients with cervical carcinoma in stage Ia in the years 1966 to 1986].","authors":"A Schumacher, R Schwarz","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>All histological specimens obtained from patients with Stage-Ia cervical carcinoma, between 1966 and 1986, were re-examined and reclassified in a retrospective study for the purpose of checking on the validity of prognostic factors with relevance to cervical carcinoma at Stage Ia. The criteria valid at present were satisfied by 226 cases. No accurate sub-division by sub-groups Ia1 and Ia2 was possible by tumor measurement. Multicentric tumors were recorded in eight cases. Conisation proved to be an optimum approach to diagnosis of Stage-Ia cervical carcinoma. The percentual amount of histologically identified koilocytosis as an expression of preceding virus infections went up with significance from 13 to 34%. Maximum infiltration of 3 mm in depth was exhibited by 93% all tumours, while 5 mm infiltration was recorded by seven per cent. Significant correlations were found to exist between depth of infiltration, tumour volume, shape of growth, degree of differentiation, and involvement of lymphatic vessels.</p>","PeriodicalId":23840,"journal":{"name":"Zentralblatt fur allgemeine Pathologie u. pathologische Anatomie","volume":"135 7","pages":"639-48"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13730743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Regression of human arteriosclerosis].","authors":"G Lusztig, J Lesznyák","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>An account is given of possibilities and mechanisms of regression of arteriosclerosis. Reference is made to animal experiments and to angiographic investigations of man, and the assumption is derived that even in man arteriosclerosis is to a certain extent capable of regression. This view applies preferentially to lipidous alterations. A distinction is made between two mechanisms underlying regression. One of them is attributed to reduction of existing hypercholesterolaemia, while the other is related to regression via action of so far unknown wall factors, without lowering of blood cholesterol.</p>","PeriodicalId":23840,"journal":{"name":"Zentralblatt fur allgemeine Pathologie u. pathologische Anatomie","volume":"135 6","pages":"549-52"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13825496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Oncocytic paraganglioma of the carotid body].","authors":"I Michailow, B Alexiew","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>One case of benign oncocytic paraganglioma which had originated from the non-chromaffin cells of the carotid body in a woman, 66 years of age, is described in this paper. The microscopic pattern of the tumor consisted mainly of large, round, eosinophilic cells arranged in solid nests and sheets. Pale rather than eosinophilic cells of polygonal shape were predominant in the peripheral areas. Ultrastructural analysis revealed the presence of three cell types: oncocytes, cells with electron-dense granules, 150 to 200 nm in size, and transitional forms between these two. Possible development of oncocytes from APUD cells is discussed.</p>","PeriodicalId":23840,"journal":{"name":"Zentralblatt fur allgemeine Pathologie u. pathologische Anatomie","volume":"135 4","pages":"363-7"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13920799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Congenital ependymoma. Case report and immunohistochemical studies].","authors":"N Heye, J Iglesias, S Huber, H Lobeck","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Reported in this paper is a congenital ependymoma in an 23-week old foetus. The neoplasm was well vascularised and contained typical ependymal rosettes. The tumour cells did not react with GFAP-antiserum. They reacted weakly with neuron-specific enolase and vimentin and exhibited strong antigenicity with S-100-protein-antiserum. Cytokeratin antigen was recordable from some tumour cells. The tumour was sufficiently mature for classification as ependymoma. Immunohistochemical findings suggested possible ectodermal origin of the tumour cells.</p>","PeriodicalId":23840,"journal":{"name":"Zentralblatt fur allgemeine Pathologie u. pathologische Anatomie","volume":"135 1","pages":"43-9"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13613093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Problems in the documentation of autopsy findings on death certificates for stillborn babies and deaths of babies under one year of age].","authors":"H Zschoch, S Dassler","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Analysis of 311 death certificates issued on stillbirths and deaths below one year of age, between 1979 and 1984, together with checks on all clinical data in them revealed a great number of erroneous entries by pathologists. These included using of wrong printed lines, reference to wrong ICD classes, disagreement between verbal notes and ICD code, statement of unimportant changes as causes of death, and mistakes in defining basic diseases. Error rates are reported and discussed. Pathologists quite often failed to take sufficient advantage of the possibility of stating a multicausative background of death.</p>","PeriodicalId":23840,"journal":{"name":"Zentralblatt fur allgemeine Pathologie u. pathologische Anatomie","volume":"135 7","pages":"689-94"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13730747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Problems of agreement of clinical and autopsy diagnoses].","authors":"F Vollmar","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Results obtained from autopsy are parameters of importance to efficacy of diagnosis and therapy. To enable better overseeability of higher numbers of cases, the necessary congruence between clinical and postmortem diagnoses should be consistently settled on the basis of identical criteria used by clinicians and pathologists. Aspects relating to the problem are discussed in some detail, and suggestions are made on how to formulate final evaluations in postmortem reports.</p>","PeriodicalId":23840,"journal":{"name":"Zentralblatt fur allgemeine Pathologie u. pathologische Anatomie","volume":"135 7","pages":"699-704"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13730749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}