[Histomorphologic and catamnestic studies of 226 patients with cervical carcinoma in stage Ia in the years 1966 to 1986].

Abstract

All histological specimens obtained from patients with Stage-Ia cervical carcinoma, between 1966 and 1986, were re-examined and reclassified in a retrospective study for the purpose of checking on the validity of prognostic factors with relevance to cervical carcinoma at Stage Ia. The criteria valid at present were satisfied by 226 cases. No accurate sub-division by sub-groups Ia1 and Ia2 was possible by tumor measurement. Multicentric tumors were recorded in eight cases. Conisation proved to be an optimum approach to diagnosis of Stage-Ia cervical carcinoma. The percentual amount of histologically identified koilocytosis as an expression of preceding virus infections went up with significance from 13 to 34%. Maximum infiltration of 3 mm in depth was exhibited by 93% all tumours, while 5 mm infiltration was recorded by seven per cent. Significant correlations were found to exist between depth of infiltration, tumour volume, shape of growth, degree of differentiation, and involvement of lymphatic vessels.