Wounds : a compendium of clinical research and practice最新文献

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Evaluation of risk factors for foot ulceration in individuals with chronic kidney disease. 评估慢性肾病患者足部溃疡的风险因素。
IF 1.7 4区 医学
Wounds : a compendium of clinical research and practice Pub Date : 2023-10-01 DOI: 10.25270/wnds/23053
Vacide Aşık Özdemir, Nesrin Nural
{"title":"Evaluation of risk factors for foot ulceration in individuals with chronic kidney disease.","authors":"Vacide Aşık Özdemir, Nesrin Nural","doi":"10.25270/wnds/23053","DOIUrl":"https://doi.org/10.25270/wnds/23053","url":null,"abstract":"INTRODUCTION CKD, like DM, is an independent risk factor for the development and course of foot ulcers. OBJECTIVE The authors studied the incidence and risk factors of foot ulceration in patients with CKD and with or without DM and in patients receiving or not receiving HD. MATERIALS AND METHODS Patients with or without DM and with renal failure were divided into 4 groups of 40 patients each according to whether or not they were receiving HD. Data were collected using a patient information form, physical examination of the foot, and risk assessment forms. RESULTS Lower extremity ulceration was highest in group 3 (HD+DM+) (15% [6 of 40]), that is, in patients with CKD and DM receiving HD (P = .421). Patients in group 3 were at highest risk for foot ulcers (72.5%) compared with other groups (P = .001). Risk factors associated with foot ulceration were advanced stage (ie, stage 4 or 5) CKD, HD treatment, age, BMI, history of lower extremity ulceration and/or amputation, foot deformities, skin and nail pathology, neuropathy, and vascular insufficiency. CONCLUSIONS Patients with CKD receiving HD are at high risk for foot ulcers, and this risk increases with the presence of DM.","PeriodicalId":23752,"journal":{"name":"Wounds : a compendium of clinical research and practice","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139325667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comment: enhancing complex wound care by leveraging artificial intelligence. 评论:利用人工智能加强复杂伤口护理。
IF 1.7 4区 医学
Wounds : a compendium of clinical research and practice Pub Date : 2023-10-01 DOI: 10.25270/wnds/23125
A. Kleebayoon, V. Wiwanitkit
{"title":"Comment: enhancing complex wound care by leveraging artificial intelligence.","authors":"A. Kleebayoon, V. Wiwanitkit","doi":"10.25270/wnds/23125","DOIUrl":"https://doi.org/10.25270/wnds/23125","url":null,"abstract":"","PeriodicalId":23752,"journal":{"name":"Wounds : a compendium of clinical research and practice","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139326157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Partial transection of the external ear caused by a mask worn for COVID-19 protection. COVID-19 防护面具造成外耳部分横断。
IF 1.7 4区 医学
Wounds : a compendium of clinical research and practice Pub Date : 2023-10-01 DOI: 10.25270/wnds/23070
Fuko Omine, Junya Oshima, Yasushi Haga
{"title":"Partial transection of the external ear caused by a mask worn for COVID-19 protection.","authors":"Fuko Omine, Junya Oshima, Yasushi Haga","doi":"10.25270/wnds/23070","DOIUrl":"https://doi.org/10.25270/wnds/23070","url":null,"abstract":"INTRODUCTION During the COVID-19 pandemic surgical mask-wearing was widely adopted as a means of preventing infections, but there have been several reports of mask-induced skin problems. In this report, we describe a case in which surgery was required for a mask-induced ear injury. CASE REPORT An otherwise healthy 63-year-old male presented to the plastic surgery department with an auricle injury. He had been using a mask that was too small for his face for more than 1 month; the tight ear loops caused the upper part of his left auricle to begin to dissect, resulting in a large tear. More than a third of the left upper auricle was torn, and the wound surface was epithelialized. The patient had no history of skin disease or psychiatric disorder but was engaged in a job that required wearing a helmet constantly. Surgery was performed to refresh the epithelialized wound surface and suture it, and the patient healed without complication. CONCLUSION While mask-wearing mandates and recommendations have considerably eased since the height of the pandemic, the current authors' experience has brought to light problems related to mask usage. Thus, efforts should be made to investigate the causes of these problems and provide appropriate advice.","PeriodicalId":23752,"journal":{"name":"Wounds : a compendium of clinical research and practice","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139326829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Partial transection of the external ear caused by a mask worn for COVID-19 protection. 因佩戴COVID-19防护口罩导致外耳部分横断。
IF 1.7 4区 医学
Fuko Omine, Junya Oshima, Yasushi Haga
{"title":"Partial transection of the external ear caused by a mask worn for COVID-19 protection.","authors":"Fuko Omine, Junya Oshima, Yasushi Haga","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>During the COVID-19 pandemic surgical mask-wearing was widely adopted as a means of preventing infections, but there have been several reports of mask-induced skin problems. In this report, we describe a case in which surgery was required for a mask-induced ear injury.</p><p><strong>Case report: </strong>An otherwise healthy 63-year-old male presented to the plastic surgery department with an auricle injury. He had been using a mask that was too small for his face for more than 1 month; the tight ear loops caused the upper part of his left auricle to begin to dissect, resulting in a large tear. More than a third of the left upper auricle was torn, and the wound surface was epithelialized. The patient had no history of skin disease or psychiatric disorder but was engaged in a job that required wearing a helmet constantly. Surgery was performed to refresh the epithelialized wound surface and suture it, and the patient healed without complication.</p><p><strong>Conclusion: </strong>While mask-wearing mandates and recommendations have considerably eased since the height of the pandemic, the current authors' experience has brought to light problems related to mask usage. Thus, efforts should be made to investigate the causes of these problems and provide appropriate advice.</p>","PeriodicalId":23752,"journal":{"name":"Wounds : a compendium of clinical research and practice","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"92156860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Medical mythology, misconceptions, and misinformation: does iodine impede wound healing? 医学神话、误解和错误信息:碘会阻碍伤口愈合吗?
IF 1.7 4区 医学
Christopher Girgis, Mehmet A Suludere, P Andrew Crisologo, Lawrence A Lavery
{"title":"Medical mythology, misconceptions, and misinformation: does iodine impede wound healing?","authors":"Christopher Girgis,&nbsp;Mehmet A Suludere,&nbsp;P Andrew Crisologo,&nbsp;Lawrence A Lavery","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>PI has been shown to be effective against a broad spectrum of bacteria and to be cytotoxic to a variety of cell types. Such findings led to the widespread belief that PI interferes with wound healing.</p><p><strong>Objective: </strong>This article reviews laboratory studies, animal wound studies, and clinical studies that examine the efficacy and safety of iodine-based wound products in wound healing.</p><p><strong>Methods: </strong>The authors searched PubMed and Scopus databases without time restrictions, and 62 articles were selected for complete evaluation. Fourteen RCTs and 5 comparative studies that evaluated PI and 15 RCTs that evaluated CI were included.</p><p><strong>Results: </strong>In 63% (n = 12) of the PI studies, there was no difference between PI and controls and in 5% (n = 1) PI performed significantly better than the comparator. In 31% (n = 6), outcomes were better with controls than with PI. In the RCTs on CI, 64% (n = 9) of the studies found no difference between CI and controls. Thirty-five percent (n = 5) showed significantly positive influence of CI compared with controls.</p><p><strong>Conclusions: </strong>Both CI and PI appear to be safe, with no evidence that these products impede wound healing, are associated with more infections, or require more amputations compared with other modalities. PI can effectively be used for short periods of time, and CI is an effective wound care modality for chronic wounds.</p>","PeriodicalId":23752,"journal":{"name":"Wounds : a compendium of clinical research and practice","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41155561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Urinary bladder matrix devices support closure in complex sacral wounds. 膀胱基质装置支持闭合复杂的骶骨伤口。
IF 1.7 4区 医学
Harrison M Cotler, Hannah B Baker
{"title":"Urinary bladder matrix devices support closure in complex sacral wounds.","authors":"Harrison M Cotler,&nbsp;Hannah B Baker","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The management of sacral wounds is often complicated by patient comorbidities and anatomical factors. This retrospective case series describes the management of 5 complex sacral wounds in which UBM devices were applied to facilitate wound closure. The wounds in this series were exacerbated by comorbidities and challenging wound presentations including tunneling and exposed bone. In this series, application of UBM particulate and sheets supported progressive wound closure, marked by neo-tissue formation and depth reduction with closure of tunneling in all cases. Results from this series underscore the utility of UBM devices in the management of sacral wounds and especially those further hindered by extensive tunneling.</p>","PeriodicalId":23752,"journal":{"name":"Wounds : a compendium of clinical research and practice","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41138267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Three-year experience with combined complex skin repair in patients with extensive burns: a retrospective study. 大面积烧伤患者联合复杂皮肤修复的三年经验:一项回顾性研究。
IF 1.7 4区 医学
Xingxin Gao, Min Zhang, Dezhi Song, Jialing Wei, Yuan Lin, Yajun Wu, Chaoyi Zhong, Dehui Li, Bangde Xiang
{"title":"Three-year experience with combined complex skin repair in patients with extensive burns: a retrospective study.","authors":"Xingxin Gao,&nbsp;Min Zhang,&nbsp;Dezhi Song,&nbsp;Jialing Wei,&nbsp;Yuan Lin,&nbsp;Yajun Wu,&nbsp;Chaoyi Zhong,&nbsp;Dehui Li,&nbsp;Bangde Xiang","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>The Meek micrografting technique used in STSG expansion is effective in achieving wide and rapid coverage of burn wounds. Certain growth factors have also been shown to modulate or mediate wound healing.</p><p><strong>Objective: </strong>In this study, a combined treatment approach for severe burns involving the Meek micrografting technique, systemic application of rhGH, and topical application of rhEGF was evaluated.</p><p><strong>Materials and methods: </strong>A retrospective study was conducted of 7 extensively burned patients who were treated with the Meek technique, systemic application of rhGH, and topical application of rhEGF between January 2017 and December 2019.</p><p><strong>Results: </strong>The mean percent TBSA burned was 89%. An average of 9.5 surgical procedures were performed to obtain skin cover, with an average of 5.8 Meek micrograft procedures performed in the 6 surviving patients. Complete wound healing was achieved at an average of 120 days in the 6 surviving patients. The mean graft take rate was 81%. Infection was the main reason for graft failure. Donor sites were used for up to 5 re-harvestings without additional morbidity.</p><p><strong>Conclusions: </strong>A multipronged treatment approach that combines the Meek micrografting technique, systemic application of rhGH, and topical application of rhEGF is a promising tool for the management of severe and extensive burns.</p>","PeriodicalId":23752,"journal":{"name":"Wounds : a compendium of clinical research and practice","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41156566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effectiveness of a purified type I collagen matrix plus the antimicrobial polyhexamethylene biguanide for use in cutaneous wounds: analysis of a population of three combined registries. 纯化的I型胶原基质加抗微生物聚六亚甲基双胍用于皮肤伤口的有效性:对三个联合登记的人群的分析。
IF 1.7 4区 医学
Scott A Gorenstein, Michael A Bain, Alisha Oropallo, George Koullias, Michael Leon Sabolinski
{"title":"Effectiveness of a purified type I collagen matrix plus the antimicrobial polyhexamethylene biguanide for use in cutaneous wounds: analysis of a population of three combined registries.","authors":"Scott A Gorenstein,&nbsp;Michael A Bain,&nbsp;Alisha Oropallo,&nbsp;George Koullias,&nbsp;Michael Leon Sabolinski","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Chronic wounds represent a significant burden to the health care system and patients.</p><p><strong>Objective: </strong>This study determined the effectiveness of a wound scaffold comprised of PCMP for use in nonhealing, cutaneous wounds; this study analyzes pooled data from the population of 3 combined registries.</p><p><strong>Materials and methods: </strong>A total of 3 combined registry populations were pooled from a single-center study of 41 patients, a single-center study of 86 patients, and the RESPOND Registry of 307 patients treated at 28 centers. All 434 patients received PCMP and were followed for up to 48 weeks. Male and female patients 18 years or older with wounds between 0.2 cm2 and 200 cm2 were included.</p><p><strong>Results: </strong>In total, there were 95 VLUs, 78 DFUs, 90 PIs, 73 PSWs, and 98 wounds of other etiologies analyzed. The mean baseline area, depth, and volume of all 434 wounds was 15.1 cm2, 4.9 mm, and 7.2 cm3, respectively. K-M median time to wound closure for all wounds was 19 weeks. At weeks 20, 24, 28, and 48, the frequency of wound closure for all wounds was 51%, 56%, 62%, and 72%, respectively. The median time to closure by wound type was 22 weeks for VLUs, 24 weeks for DFUs, 23 weeks for PIs, 12 weeks for PSWs, and 14 weeks for other wounds. The proportion of wounds closed were 72% (VLUs), 52% (DFUs), 63% (PIs), 95% (PSWs), and 67% (other etiologies).</p><p><strong>Conclusions: </strong>This 434-patient PCMP cohort analysis showed 72% wound closure and median time to wound closure of 19 weeks. PCMP demonstrated effectiveness for use in multiple wound types.</p>","PeriodicalId":23752,"journal":{"name":"Wounds : a compendium of clinical research and practice","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41167497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dehydrated human amnion/chorion membrane allograft for postoperative wounds following Mohs micrographic surgery: a retrospective comparative evaluation. Mohs显微外科手术后脱水人羊膜/绒毛膜同种异体移植物治疗术后伤口的回顾性比较评价。
IF 1.7 4区 医学
Sadaf Moradi, Ana Ormaza, Navid Ezra
{"title":"Dehydrated human amnion/chorion membrane allograft for postoperative wounds following Mohs micrographic surgery: a retrospective comparative evaluation.","authors":"Sadaf Moradi,&nbsp;Ana Ormaza,&nbsp;Navid Ezra","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Defects that remain after MMS cannot always be repaired immediately. When closure is not feasible, wounds are left to heal by secondary intention and may take weeks to close. In such cases, the use of an allograft that stimulates endogenous wound healing pathways may be desirable.</p><p><strong>Objective: </strong>This retrospective study assessed whether the use of dHACM allograft after MMS led to a statistically significant improvement in post-Mohs wound closure rates compared with secondary intention healing.</p><p><strong>Methods: </strong>This study evaluated 80 patients who underwent MMS and compared time to complete healing between wounds treated with dHACM allografts (n = 40) and wounds healed by secondary intention (n = 40). Wounds were assessed every 2 weeks, and photographs were taken. Statistical analysis was conducted.</p><p><strong>Results: </strong>Average time to complete wound healing was significantly reduced with the use of dHACM allograft compared with traditional secondary intention healing (5.2 weeks and 6.5 weeks, respectively; P = .01).</p><p><strong>Conclusion: </strong>The use of dHACM allograft resulted in more rapid wound healing, and this allograft is a potential alternative to traditional secondary intention healing methods. Further studies are needed to reinforce the results of this pilot study.</p>","PeriodicalId":23752,"journal":{"name":"Wounds : a compendium of clinical research and practice","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41103691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical management of nonuremic calcific arteriolopathy: a report of three cases. 非缓解性钙化性动脉病变的临床治疗:附3例报告。
IF 1.7 4区 医学
Laura Swoboda
{"title":"Clinical management of nonuremic calcific arteriolopathy: a report of three cases.","authors":"Laura Swoboda","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Calcific arteriolopathy involves the deposition of insoluble calcium salts in the vasculature and soft tissues, leading to ischemia, thrombosis, and cutaneous necrosis. Calcific arteriolopathy is commonly associated with ESRD but can also occur outside of ESRD, known as NUC.</p><p><strong>Objective: </strong>This article reviews the clinical management and outcomes of 3 cases of non-uremic calcific arteriolopathy.</p><p><strong>Materials and methods: </strong>This case series describes the clinical presentation and successful treatment of NUC in a community hospital-based outpatient wound center in southeastern Wisconsin. Factors presumed to be involved included chronic kidney disease-associated mineral bone disorder, dysregulation and deficiencies of the inhibitors of vascular calcifications, autoimmune dysfunction, and chronic inflammation. All 3 patients received multimodal treatment with wound hygiene, pain management, and infection control. In addition to these interventions, case 2 received NLFU.</p><p><strong>Results: </strong>All 3 patients displayed increased tolerance of compression and debridement and successfully epithelialized with no discernible effect on long-term function or quality of life. Wound infection occurred in each case. The mean overall healing time was 20 weeks.</p><p><strong>Conclusion: </strong>The study findings suggest that successful management of NUC can be achieved using IV STS, early and aggressive infection treatment, pain control, and wound hygiene. In patients with NUC, NLFU may be an appropriate adjunct to expedite healing.</p>","PeriodicalId":23752,"journal":{"name":"Wounds : a compendium of clinical research and practice","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41150868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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