Yearbook of Paediatric Endocrinology最新文献_第9页

Postprandial glycaemic dips predict appetite and energy intake in healthy individuals 餐后血糖下降可预测健康人的食欲和能量摄入

Yearbook of Paediatric Endocrinology Pub Date : 2022-09-12 DOI: 10.1530/ey.19.15.2

Wyatt P, Berry Se, Finlayson G, O'Driscoll R, Hadjigeorgiou G, Drew Da, Khatib Ha, Nguyen Lh, Linenberg I, Chan At, Spector Td, Franks Pw, W. J., Blundell J, Valdes Am

引用次数: 1

Transient vs permanent congenital hypothyroidism in Ontario, Canada: predictive factors and scoring system 加拿大安大略省暂时性与永久性先天性甲状腺功能减退:预测因素和评分系统

Yearbook of Paediatric Endocrinology Pub Date : 2022-09-12 DOI: 10.1530/ey.19.3.8

M. A., Yokubynas N, T. K, Saleh D, Wherrett Dk, S. R, Bassilious E, C. P, Lawrence Se

引用次数: 0

Yearbook of Paediatric Endocrinology Pub Date : 2022-09-12 DOI: 10.1530/ey.19.13.17

Daniel R, Yadav J, K. R., Malhi P, S. A, Dayal D

引用次数: 0

Fine-mapping, trans-ancestral and genomic analyses identify causal variants, cells, genes and drug targets for type 1 diabetes 精细制图、跨祖先和基因组分析确定了1型糖尿病的致病变异、细胞、基因和药物靶点

Yearbook of Paediatric Endocrinology Pub Date : 2022-09-12 DOI: 10.1530/ey.19.10.16

Roberts Cc, Inshaw Jrj, O. S, Chen Wm, DF Santa Cruz, Y. H, Cutler Aj, Crouch Djm, F. E, Bridges Sl, Edberg Jc, Kimberly Rp, Buckner Jh, Deloukas P, D. J, Dabelea D, Lawrence Jm, Marcovina S, Shahjahan As, Greenbaum Cj, Atkinson Ma, Gregersen Pk, Oksenberg Jr, P. F., Rewers Mj, Steck Ak, Dunger Db, Wicker Ls, C. P., Todd Ja, Rich Ss

引用次数: 1

Pathogenic variants in RNPC3 are associated with hypopituitarism and primary ovarian insufficiency RNPC3的致病变异与垂体功能低下和原发性卵巢功能不全有关

Yearbook of Paediatric Endocrinology Pub Date : 2022-09-12 DOI: 10.1530/ey.19.1.7

Akin L, Rizzoti K, Gregory Lc, Corredor B, Stabej P Le Quesne, W. H., Buonocore F, Mouilleron S, Capra V, McGlacken-Byrne Sm, Martos-Moreno Ga, Azmanov Dn, Kendirci M, Kurtoglu S, Suntharalingham Jp, Galichet C, Gustincich S, Tasic V, Acherman Jc, A. A, Filipovska A, Tuilpakov A, Maghnie M, Gucev Z, Gonen Zb, P. La, R. I., Lovell-Badge R, Argente J, Dattani Mt

引用次数: 0

Lymphocyte infiltration and thyrocyte destruction are driven by stromal and immune cell components in Hashimotos thyroiditis 桥本甲状腺炎中淋巴细胞浸润和甲状腺细胞破坏是由基质细胞和免疫细胞成分驱动的

Yearbook of Paediatric Endocrinology Pub Date : 2022-09-12 DOI: 10.1530/ey.19.3.11

Zhang Qy, Ye Xp, Z. Z, Zhu Cf, L. R., Fang Y, Zhang Rj, L. L, L. W, W. Z, Song Sy, Luthfi Sy, Zhao Sx, Lin Jn, Song Hd

引用次数: 0

Testing for rare genetic causes of obesity: findings and experiences from a pediatric weight management program 检测罕见的肥胖遗传原因:来自儿科体重管理项目的发现和经验

Yearbook of Paediatric Endocrinology Pub Date : 2022-09-12 DOI: 10.1530/ey.19.11.1

Robertson Kj, Ariza Aj, S. K., Quadri M, M. C., Neault S, Davis Ee, Binns Hj

引用次数: 0

Type 1 Diabetes 1型糖尿病

Yearbook of Paediatric Endocrinology Pub Date : 2022-09-12 DOI: 10.1530/ey.19.10

M. Marcovecchio

引用次数: 0

Broad-spectrum XX and XY gonadal dysgenesis in patients with a homozygous L193S variant in PPP2R3C PPP2R3C纯合子L193S变异患者的广谱XX和XY性腺发育不良

Yearbook of Paediatric Endocrinology Pub Date : 2022-09-12 DOI: 10.1530/ey.19.6.5

C. D., Warr N, Yesil G, H. K. Eker, Bas F, Poyrazoglu S, Darendeliler F, Direk G, Hatipoglu N, E. M, Z. Y. Abalı, B. G. Tosun, Kaygusuz Sb, T. S. Menevşe, Helvacioglu D, Turan S, Bereket A, Reeves R, S. M, M. M., T. L., Greenfield A, G. T

引用次数: 0

Should Dehydroepiandrosterone be administered to women? 女性是否应该使用脱氢表雄酮?

Yearbook of Paediatric Endocrinology Pub Date : 2022-09-12 DOI: 10.1530/ey.19.8.14

Wierman Me, Kiseljak-Vassiliades K

{"title":"Should Dehydroepiandrosterone be administered to women?","authors":"Wierman Me, Kiseljak-Vassiliades K","doi":"10.1530/ey.19.8.14","DOIUrl":"https://doi.org/10.1530/ey.19.8.14","url":null,"abstract":"Context: Androgen prohormones such as dehydroepiandrosterone (DHEA) increase in early puberty, peak in the second and third decade, and thereafter decline, independent of menopausal status. Investigators have examined their potential beneficial effects in normal women and those with DHEA-deficient states. Evidence Acquisition: A review of the literature from 1985 to 2021 on the potential benefits and risks of androgen prohormones in women. Evidence Synthesis: Studies have examined the potential benefit of DHEA therapy for anti-aging, sexual dysfunction, infertility, metabolic bone health, cognition, and wellbeing in hormone-deficient states such as primary adrenal insufficiency, hypopituitarism, and anorexia as well as administration to normal women across the lifespan. Conclusions: Data support small benefits in quality of life and mood but not for anxiety or sexual function in women with primary or secondary adrenal insufficiency or anorexia. No consistent beneficial effects of DHEA administration have been observed for menopausal symptoms, sexual function, cognition, or overall wellbeing in normal women. Local administration of DHEA shows benefit in vulvovaginal atrophy. Use of DHEA to improve induction of ovulation response in women with diminished ovarian reserve is not recommended. Risks of high physiologic or pharmacologic use of DHEA include androgenic and estrogenic side effects which are of concern for long-term administration. Clinical Case: A 49-year-old woman with Addison’s disease who is on low dose estrogen with cyclic progesterone therapy for menopausal symptoms returns for follow-up. She is on a stable glucocorticoid replacement strategy of hydrocortisone 10 mg in the morning and 5 mg in the early afternoon and fludrocortisone 0.05 mg each morning. She has read on the internet that additional therapy with DHEA may help her overall quality of life and libido. She asks whether she should add this therapy to her regimen and at what dose.","PeriodicalId":23743,"journal":{"name":"Yearbook of Paediatric Endocrinology","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78195616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3