World Journal of Biology Pharmacy and Health Sciences最新文献_第2页

Current review on nail drug delivery system and their future perspectives 指甲给药系统及其未来展望综述

World Journal of Biology Pharmacy and Health Sciences Pub Date : 2024-07-30 DOI: 10.30574/wjbphs.2024.19.1.0444

Lalit Sharma, Navneet Mehan, Ritika Chouhan, Suman Anjali, Vaibhav Kumar, KM Rekha, Kunal Kumar, Naman Kumar

{"title":"Current review on nail drug delivery system and their future perspectives","authors":"Lalit Sharma, Navneet Mehan, Ritika Chouhan, Suman Anjali, Vaibhav Kumar, KM Rekha, Kunal Kumar, Naman Kumar","doi":"10.30574/wjbphs.2024.19.1.0444","DOIUrl":"https://doi.org/10.30574/wjbphs.2024.19.1.0444","url":null,"abstract":"Human nails are not only beautiful and protective, but they may also be utilized as a vehicle for drug delivery, particularly in the treatment of nail disorders such as psoriasis and onychomycosis. Even though nails develop at a somewhat moderate rate, their highly keratinized structure presents unique opportunities and challenges for medication penetration. Achieving therapeutic doses might be difficult even with topical pharmaceutical delivery, which offers advantages like non-invasiveness and customized effect. Many physical and chemical methods, such as acid etching and permeation enhancers, have been studied to improve drug penetration. It has recently been demonstrated that nail lacquers have potential for effectively delivering medication through the nails. Nail anatomy, common nail diseases, nail medication administration methods, and the advantages and disadvantages of nail lacquers are all covered in this overview. In addition, it discusses factors influencing drug diffusion through nails, draws comparisons between topical nail lacquers and oral antifungal medications, and looks at recent studies and patents on the topic. Future prospects for transungual medicine administration are promising, thanks to innovations such as photodynamic therapy and water-based lacquers. To fully realize the promise of this distribution method, more research is necessary.","PeriodicalId":23738,"journal":{"name":"World Journal of Biology Pharmacy and Health Sciences","volume":"10 16","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141796273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prevalence of internet addiction and its impact on socio educational area among students of selected high schools at urban areas of Davangere, Karnataka 卡纳塔克邦达万格尔城区部分高中学生的网瘾流行率及其对社会教育领域的影响

World Journal of Biology Pharmacy and Health Sciences Pub Date : 2024-07-30 DOI: 10.30574/wjbphs.2024.19.1.0392

Venu A.S, Uday Kumar Rao, Rangappa S Ashi

{"title":"Prevalence of internet addiction and its impact on socio educational area among students of selected high schools at urban areas of Davangere, Karnataka","authors":"Venu A.S, Uday Kumar Rao, Rangappa S Ashi","doi":"10.30574/wjbphs.2024.19.1.0392","DOIUrl":"https://doi.org/10.30574/wjbphs.2024.19.1.0392","url":null,"abstract":"Background: The Internet has developed into one of man's most important tools for information, employment possibilities, education, entertainment, social media, and networking, and it is progressively becoming an integral part of our daily lives. Objectives: To assess prevalence of internet addiction and its impact on socio educational area among students at selected high schools of urban areas of Davangere. Methodology: A quantitative approach with descriptive survey research design was adopted for the study. The samples from the selected high schools of urban areas were selected using probability multistage random sampling technique. The sample consisted of 200high school students. A Internet addiction test developed by Dr. Young was used to measure the internet addiction and questionnaire on Impact of internet addiction on socio educational area was used to measure impact. Results: The study result reveal that, internet addiction mean internet addiction score was 34.24, median was 34.50, mode was 25, standard deviation 11.95 and range score was 1-75. Majority 82(41%) were not had internet addiction, 83(41.5%) were had mild addiction and least 35(17.5%) of participant was had moderate level of internet addiction. With respect to impact of internet addiction on socio educational area, majority 48(43.63%) were had mild impact, 38(34.54%) were had moderate impacts and least 32(29.09%) of participants were not had impact on socio educational area. The levels of internet addiction of participants of urban area are found to be statistically significant at 0.05 levels for gender, occupation of mothers and time spent daily on internet Conclusion: The study can help policymakers to understand the burden of internet addiction among adolescent students and can make necessary changes in the education system.","PeriodicalId":23738,"journal":{"name":"World Journal of Biology Pharmacy and Health Sciences","volume":"16 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141796498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A narrative review of pharmacological and phytochemical properties of decorative flowering plants at Hyde Park Zoo Sanctuary and Tropical Gardens Inc., Guyana 圭亚那海德公园动物园和热带花园装饰性开花植物的药理和植物化学特性综述

World Journal of Biology Pharmacy and Health Sciences Pub Date : 2024-07-30 DOI: 10.30574/wjbphs.2024.19.1.0400

Kimberly Craig, Reshma Persaud

{"title":"A narrative review of pharmacological and phytochemical properties of decorative flowering plants at Hyde Park Zoo Sanctuary and Tropical Gardens Inc., Guyana","authors":"Kimberly Craig, Reshma Persaud","doi":"10.30574/wjbphs.2024.19.1.0400","DOIUrl":"https://doi.org/10.30574/wjbphs.2024.19.1.0400","url":null,"abstract":"Throughout history, plants have been used for their medicinal properties due to their ability to produce biochemical compounds. However, the safe use of these plants is a cause for concern due to only some species being medically tested and regulated. This research has utilised existing published information to provide a review which could serve as a global data resource to lend support to medical research. Hyde Park Zoo consists of ninety-nine (99) species of plants belonging to twenty (20) families of which eight (8) species of the decorative flowering plants were found to have medicinal properties based on existing literature. All eight (8) species were found to have antibacterial properties while three (3) species were found to have antifungal properties. Yellow Bellflower (Allamanda cathartica) was the only species noted to have antiviral properties while two (2) species have anticancer properties. Two (2) species aid with circulatory issues and one (1) species aids with arthritis. Hungarian Rose (Rosa gallica var) was noted to have psychotherapeutic effects aiding with depression through aromatherapy.","PeriodicalId":23738,"journal":{"name":"World Journal of Biology Pharmacy and Health Sciences","volume":"2 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141795617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Formulation of fenofibrate capsules by dropping method using PEG 6000 and PEG 4000 to enhance solubility 使用 PEG 6000 和 PEG 4000 通过滴注法配制非诺贝特胶囊以提高溶解度

World Journal of Biology Pharmacy and Health Sciences Pub Date : 2024-07-30 DOI: 10.30574/wjbphs.2024.19.1.0409

Gowtham Mandadapu, Prachetha Kolli, Kurra Venkata Gopaiah, Ramya Teja Medarametla, G. Rajesh

{"title":"Formulation of fenofibrate capsules by dropping method using PEG 6000 and PEG 4000 to enhance solubility","authors":"Gowtham Mandadapu, Prachetha Kolli, Kurra Venkata Gopaiah, Ramya Teja Medarametla, G. Rajesh","doi":"10.30574/wjbphs.2024.19.1.0409","DOIUrl":"https://doi.org/10.30574/wjbphs.2024.19.1.0409","url":null,"abstract":"The primary aim of the study was to enhance the dissolution rate of fenofibrate, a poorly soluble drug classified under BCS class II. To achieve this, solid dispersions were formulated using the dropping method with polyethylene glycol (PEG) 4000 and PEG 6000 at ratios of 1:1 and 1:2. These formulations were encapsulated and subjected to various evaluations, including solubility tests, assays, FTIR, X-ray diffraction (XRD), differential scanning calorimetry (DSC), and in-vitro dissolution studies. The most effective formulation was then compared to a commercially available product. The formulation identified as D4, which utilized PEG 6000 at a 1:2 ratio via the dropping method, exhibited the highest solubility at 0.678 ± 0.07 mg/ml, a significant improvement over the pure drug's solubility of 0.018 mg/ml. The assay of D4 showed 98.14 ± 12%, with a practical yield of 95.25 ± 0.17%. In vitro dissolution testing revealed that the solid dispersions released the drug within 60 minutes, while the D4 formulation achieved a release of 99.10 ± 0.18% in just 30 minutes. This performance was notably superior to the pure drug, which had a release rate of 27.38 ± 0.10% in 60 minutes, and comparable to the marketed micronized fenofibrate capsule (Lipicard), which had a release rate of 93.91 ± 0.12% in 30 minutes. FTIR analysis indicated no interaction between the drug and the excipients, while XRD and DSC studies confirmed that the drug in the solid dispersion was in an amorphous state. The optimized formulations demonstrated stability over time. Thus, employing the dropping method with a minimal carrier ratio of 1:2 significantly improved the drug release profile, making it comparable to the micronized fenofibrate (Lipicard).","PeriodicalId":23738,"journal":{"name":"World Journal of Biology Pharmacy and Health Sciences","volume":"10 20","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141795673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

To explore the effect of adult attachment styles on levels of self-esteem among young Indian adults 探讨成人依恋方式对印度年轻成人自尊水平的影响

World Journal of Biology Pharmacy and Health Sciences Pub Date : 2024-07-30 DOI: 10.30574/wjbphs.2024.19.1.0404

Malika Jain, Monalisa Nayak

{"title":"To explore the effect of adult attachment styles on levels of self-esteem among young Indian adults","authors":"Malika Jain, Monalisa Nayak","doi":"10.30574/wjbphs.2024.19.1.0404","DOIUrl":"https://doi.org/10.30574/wjbphs.2024.19.1.0404","url":null,"abstract":"This study investigates the influence of adult attachment styles on self-esteem levels among young Indian adults. Drawing from the Collins Adult Attachment Scale and Rosenberg Self-Esteem Scale, data was collected via online surveys administered to a convenience sample of 150 participants. The research aims to discern how attachment styles—secure, preoccupied, dismissive, and fearful—affect self-esteem perceptions. Significant findings from ANOVA and Tukey HSD tests reveal distinct patterns among attachment styles: individuals with secure attachment display the highest self-esteem, followed by preoccupied, dismissive, and fearful attachment styles, in descending order. The study underscores the importance of understanding the intricate interplay between attachment orientations and self-esteem development, shedding light on how these psychological constructs shape individuals' perceptions of themselves. Furthermore, the findings contribute to the growing body of literature on adult attachment and its implications for mental health and well-being. These insights have the potential to inform therapeutic interventions aimed at bolstering self-esteem and fostering secure attachment relationships among young adults in diverse cultural contexts","PeriodicalId":23738,"journal":{"name":"World Journal of Biology Pharmacy and Health Sciences","volume":"6 18","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141795968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Glucose variations in hypertensive patients with diabetes: A retrospective study 高血压合并糖尿病患者的血糖变化：回顾性研究

World Journal of Biology Pharmacy and Health Sciences Pub Date : 2024-07-30 DOI: 10.30574/wjbphs.2024.19.1.0397

Kalash Dwivedi, Botirova Nigina Akram qizi, Muhammed Sinan Cheelatta

{"title":"Glucose variations in hypertensive patients with diabetes: A retrospective study","authors":"Kalash Dwivedi, Botirova Nigina Akram qizi, Muhammed Sinan Cheelatta","doi":"10.30574/wjbphs.2024.19.1.0397","DOIUrl":"https://doi.org/10.30574/wjbphs.2024.19.1.0397","url":null,"abstract":"Background: Hypertension (HTN) and diabetes mellitus (DM) are prevalent chronic conditions associated with significant morbidity and mortality not only in the Uzbekistan but in the whole globe . Understanding their conjoined impact on blood sugar levels, particularly about gender-specific differences, is crucial for optimizing patient management strategies. Aim: This study aims to investigate the effect of HTN on blood sugar levels in patients with and without DM, focusing on gender-specific variations. Method: A sample of 160 patients from the Tashkent Polyclinic was categorized based on Hypertension and diabetes status. Blood sugar levels were measured using a glucometer, and statistical analyses, including t-tests, were conducted to compare blood sugar levels between groups with the help of excel . Result: Significant variations in blood sugar levels were noted between patients with both HTN and DM and those with only HTN. Gender-specific differences or variance were noted, with females exhibiting higher blood sugar levels than males, particularly in the presence of both conditions HTN and DM. Conclusion: The findings give the importance of personalized management strategies for hypertensive patients with coexisting DM, also considering gender-specific factors. Further research is warranted to elucidate the underlying mechanisms driving these differences and optimize clinical outcomes.","PeriodicalId":23738,"journal":{"name":"World Journal of Biology Pharmacy and Health Sciences","volume":"3 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141796052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Protein-enriched Akamu: Nutritional sensory and microbial quality evaluation 富含蛋白质的赤木：营养感官和微生物质量评估

World Journal of Biology Pharmacy and Health Sciences Pub Date : 2024-07-30 DOI: 10.30574/wjbphs.2024.19.1.0433

Chidinma Adanna OKAFOR, Ngozika Maria UKWUEZE

{"title":"Protein-enriched Akamu: Nutritional sensory and microbial quality evaluation","authors":"Chidinma Adanna OKAFOR, Ngozika Maria UKWUEZE","doi":"10.30574/wjbphs.2024.19.1.0433","DOIUrl":"https://doi.org/10.30574/wjbphs.2024.19.1.0433","url":null,"abstract":"Mitigating Protein Energy Malnutrition (PEM) is paramount to cohort the infant mortality rate caused by inadequate nutrition. This study examines the effect of enriching maize-based starch gruel \"Akamu\" with Bambara groundnut flour. Yellow maize was steeped for 72 hours, with the steep water changed every 24 hours. Then, wet milled, its starch separated with a cheesecloth, oven-dried and milled to produce akamu flour. Bambara groundnut was steeped, boiled, dried and milled into flour and used to enrich (10%, 20% and 30%) the akamu. The steep water was evaluated for microbial analysis, while the sample blends were examined for proximate and sensory attributes. The microbes of steep water decreased in coliform count and pH as fermentation progressed. However, Lactobacillus spp and fungi increased from 0.93x103 and 3.63x103 to 8.42x103 and 6.62x103cfu/mL, respectively. Crude protein increased significantly from 8.64 % to 15.54 %, while carbohydrates reduced to 60.20 %. The 100% maize (control) akamu showed the highest acceptability of 6.58, while 30% Bambara groundnut was the least (3.38). Hence, this study helped to establish the nutritional improvement of akamu, a cereal starch gruel with Bambara groundnut aimed at addressing malnutrition.","PeriodicalId":23738,"journal":{"name":"World Journal of Biology Pharmacy and Health Sciences","volume":"3 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141796263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Research work on an inevitable component to treat type 2 diabetes from the margin of Colocasia esculenta 关于从芋头边缘提取治疗 2 型糖尿病的必然成分的研究工作

World Journal of Biology Pharmacy and Health Sciences Pub Date : 2024-07-30 DOI: 10.30574/wjbphs.2024.19.1.0431

Bishan Sarkar, Bidisha Ghosh, Payel Choudury

引用次数: 0

Move more, sleep more? Examining the impact of exercise duration on sleep quantity among undergraduate students at the University of Washington 多运动，多睡眠？研究运动时间对华盛顿大学本科生睡眠质量的影响

World Journal of Biology Pharmacy and Health Sciences Pub Date : 2024-07-30 DOI: 10.30574/wjbphs.2024.19.1.0399

Raahul Narayanan, Esther Carpenter, Leslie Jacobo, Binqi Li, Tyler Reynolds, Jack Evers

{"title":"Move more, sleep more? Examining the impact of exercise duration on sleep quantity among undergraduate students at the University of Washington","authors":"Raahul Narayanan, Esther Carpenter, Leslie Jacobo, Binqi Li, Tyler Reynolds, Jack Evers","doi":"10.30574/wjbphs.2024.19.1.0399","DOIUrl":"https://doi.org/10.30574/wjbphs.2024.19.1.0399","url":null,"abstract":"Understanding the relationship between exercise duration and sleep quantity among undergraduate students is essential for promoting their overall health and well-being. This study investigates this association through a cross-sectional survey of 51 students aged 18-24 at the University of Washington. The results indicate an average daily exercise duration of 32 minutes and a mean sleep duration of 7.0 hours. Analysis reveals that students with higher exercise durations exhibit a 14% reduced odds of achieving high sleep quantity compared to those with lower exercise durations. Notably, caffeine consumption serves as an effect modifier in this relationship. These findings suggest that increased exercise does not necessarily correlate with increased sleep in this population, emphasizing the need for a nuanced understanding of the factors influencing sleep among college students. Addressing these variables can inform the development of targeted interventions to enhance student health and academic performance.","PeriodicalId":23738,"journal":{"name":"World Journal of Biology Pharmacy and Health Sciences","volume":"9 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141795914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A short review on natural components in sunscreen 防晒霜天然成分简评

World Journal of Biology Pharmacy and Health Sciences Pub Date : 2024-07-30 DOI: 10.30574/wjbphs.2024.19.1.0420

T. Aswini, K. Dhanusha, K. Priya, R. Shalini, S. Sumithra, W. Helen

{"title":"A short review on natural components in sunscreen","authors":"T. Aswini, K. Dhanusha, K. Priya, R. Shalini, S. Sumithra, W. Helen","doi":"10.30574/wjbphs.2024.19.1.0420","DOIUrl":"https://doi.org/10.30574/wjbphs.2024.19.1.0420","url":null,"abstract":"Herbal sunscreen is a lotion, spray, or other topical treatment that uses herbs to help protect skin from UV radiation, limit sunburn and other skin damage, and lower the risk of skin cancer. It is also frequently referred to as herbal sunblock or herbal suntan lotion. Herbal sunscreens are a vital component of modern skincare regimens since they offer several benefits that tackle both health and environmental concerns. By obstructing UV rays, sunscreen composition seeks to improve protection against them. Herbal sunscreens have grown in popularity as an appealing substitute for traditional sun protection treatments as a result of the growing consumer demand for natural and environmentally friendly skincare products. Because of their antioxidant qualities and capacity to absorb UVA rays, flavonoids, phenolic compounds, and herbal oils are crucial for UV protection. Because these sunscreens are composed of minerals and plant-based ingredients, they provide effective protection against UV (ultraviolet) rays from the sun. Herbal sunscreens have attracted a lot of attention as natural substitutes for conventional sunscreens because they offer protection against harmful ultraviolet (UV) radiation while minimizing potential adverse effects linked to synthetic ingredients. An effective and sustainable alternative to traditional sunscreens are herbal sunscreens.","PeriodicalId":23738,"journal":{"name":"World Journal of Biology Pharmacy and Health Sciences","volume":"11 48","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141795660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0