IDOSR JOURNAL OF BIOCHEMISTRY, BIOTECHNOLOGY AND ALLIED FIELDS最新文献

{"title":"Preliminary Phytochemical Evaluation and Antimicrobial studies of the methanol stem bark extract of Detarium microcarpum","authors":"D. A, Shagal, M. H., Nkafamiya, I. I, Fulata, A","doi":"10.59298/idosr/jbbaf/24/91.4045","DOIUrl":"https://doi.org/10.59298/idosr/jbbaf/24/91.4045","url":null,"abstract":"Detarium microcarpum is an African native plant that grows in the wild in several African countries, notably in savannah areas. The plant has a wide therapeutic application and is often referred to as the miracle plant by the traditional herbalist. Folk medicine relies heavily on its leaves and fruits. Hence, this research was aimed at qualitatively and quantitatively estimating the phytoconstituents inherent in the plant as well as to evaluate its antimicrobial potentials. Qualitative analysis of the methanol crude extracts was carried out to identify the presence of the classes of secondary metabolites: The results of the phytochemical screening revealed the presence of alkaloids, saponins, tannins, flavonoids, steroids and Glycosides. Similarly, the quantitative estimation of these phytoconstituents revealed the following percentage of the metabolite; alkaloids (112.35 mg/100g Atropine sulfate eqv), saponins (96.84 mg/100g Gravimetric), Tannins (159.65 mg/100g Tannic acid eqv), Flavanoids (125.47 mg/100g Quarcetine eqv) Glycosides (397.53 mg/100g), Steroids (34.52 mg/100g Cholestrol), Total phenolics (228.24 mg/100 Gallic acid eqv). The paper disc diffusion method was used to determine the antimicrobial activity of the Crude methanol extract of Datarium microcarpum using standard procedures (Bauer et al 1996). The results of antimicrobial efficacies revealed that the crude methanol extract of stem bark Detarium microcarpum was effective in inhibiting the growth of the following microorganisms; Protius, Bacillus subtilis staphylococaccus aureus, Enterobacta, Eschericia coli Shigelia dysenteriae, Salmonella typhi, Pseudomonas aeruginosa, Aspergillus nigger, Aspergillus flavus, Candida albican and Rhezome. The methanol crude extract showed a broad spectrum of antimicrobial activity with minimum inhibitory concentration (MIC) from 1.0×104 to 4.0×104 . Keywords: Phytochemical, antimicrobial studies, stem bark, and Detarium microcarpum","PeriodicalId":236427,"journal":{"name":"IDOSR JOURNAL OF BIOCHEMISTRY, BIOTECHNOLOGY AND ALLIED FIELDS","volume":"20 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140734580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Extraction, Treatment and Characterization of Banana Pseudo-Stem Fibers as Potential Utility in Textile Industry","authors":"Aimable Rukundo","doi":"10.59298/idosr/jbbaf/24/91.2339","DOIUrl":"https://doi.org/10.59298/idosr/jbbaf/24/91.2339","url":null,"abstract":"Extraction, treatment and characterization of banana pseudo stem fibres was achieved. The study revealed that water retting is the best way to extract fibers, however the gummy materials bending fibres together must be weakened by boiling the fibres rich material prior to retting where the fibres were able to be extracted at 14th day of retting. The fibers were treated using NaOH for scouring while bleaching was carried out using H2O2. The treatment of fibers was conducted to get rid of fat, wax and other impurities as well as undesired colors bonded to fibers that could not be removed through water retting. The best scouring concentration of NaOH was found to be 17.5 % while the best bleaching concentration of H2O2 was found to be 2 %. More so, FTIR was carried out for both treated and untreated fibers and it was shown that wax, fat and other impurities can be removed by fibres’ scouring and bleaching. This was further confirmed by the use of Soxhlet to extract ethanol-benzene extract from both treated and untreated fibres, where untreated fibres showed a considerable weight loss while the treated fibers did not show any weight loss. Thereafter, mercerization was carried out and it was found out that the best mercerization concentration of NaOH is 15%. Furthermore, the quantitative analysis of the banana pseudo-stem fibers revealed that the fibers have, ethanol-benzene extractives of 4.2 %, pectin content of 3.07%, Lignin content of 18%, cellulose content of 68.3% and ash content of 4.2 %. The fibers showed a water, oil and vapor absorption of 71%,59 % and 8% respectively. Also, the thermal analysis showed that the degradation temperature is 370 0C while the fibers started to display thermal instability at 290 0C. Moreover, SEM and XRD analysis showed that the treatment of fibres participated in removal of wax and oil as well as other gummy materials, which also is in line with FTIR results obtained. Keywords: Extraction, Banana Pseudo-stem Fibers, Scouring, Bleaching, Mercerization, Characterization, Textile","PeriodicalId":236427,"journal":{"name":"IDOSR JOURNAL OF BIOCHEMISTRY, BIOTECHNOLOGY AND ALLIED FIELDS","volume":"42 14","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140734034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advances in Analytical Techniques and Therapeutic Applications of Phytochemicals","authors":"Chimezie O. Onukwuli, Chisom E. Izuchukwu, U. Paul-Chima","doi":"10.59298/idosr/jbbaf/24/91.1222","DOIUrl":"https://doi.org/10.59298/idosr/jbbaf/24/91.1222","url":null,"abstract":"The attentiveness towards phytochemicals, which represents the group of biologically active compounds derived from plants, also referred to as phytocomponents, and has sprung up due to their therapeutics implications. This review article encourages researchers to appreciate the most recent innovations in analytical approaches to the determination and measurement of phytochemicals, methods such as spectroscopy, chromatography and mass spectrometry are some of the techniques examined here. Moreover, it covers the bioactivity and mechanisms of action of phytochemicals, the effect of which is their being directing to molecular targets and leading to a modulation of cellular signaling network. The way that the plant-derived compounds are absorbed, distributed, metabolized and excreted (pharmacokinetics) and the way that they act on the body (pharmacodynamics) are examined in details and they are found to be efficient for treating many diseases. Drug discovery and development also include a range of interdisciplinary fields such as chemistry, pharmacology, and other disciplines. In these areas, research includes also industry considerations and ethical practices. This overview covers the range of achievements based on phytochemical research in the current stage and the expectations on its prospective influence on health care. Keywords: Phytochemicals, Analytical Techniques, Bioactivity, Pharmacokinetics and Pharmacodynamics","PeriodicalId":236427,"journal":{"name":"IDOSR JOURNAL OF BIOCHEMISTRY, BIOTECHNOLOGY AND ALLIED FIELDS","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140230664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Harnessing the Potential of Indigenous African Plants in HIV Management: A Comprehensive Review Integrating Traditional Knowledge with Evidence-Based Medicine","authors":"Chimezie O. Onukwuli, Chisom E. Izuchukwu, U. Paul-Chima","doi":"10.59298/idosr/jbbaf/24/91.111","DOIUrl":"https://doi.org/10.59298/idosr/jbbaf/24/91.111","url":null,"abstract":"Besides the fact that Africa is the cradle of humanity, the continent has got numerous indigenous plants that are utilized in traditional medicine, especially in the containment and management of the spread of HIV. This study provides an in-depth discussion on plants phytochemicals and their nutrients in African Indigenous along with the possible disease mitigation for persons with HIV. Specifying evidence-based medicine, this review analyses the impediments and possibilities of paying traditional knowledge a tribute with contemporary healthcare. It also emphasizes the vitality of community involvement, knowledge exchange as well as the future research that aims to definitely advance the understanding of the validity and ability of the indigenous African plants in the fight against HIV/AIDS. Keywords: Indigenous African plants, Phytochemicals, Nutrients, Traditional medicine, HIV/AIDS management","PeriodicalId":236427,"journal":{"name":"IDOSR JOURNAL OF BIOCHEMISTRY, BIOTECHNOLOGY AND ALLIED FIELDS","volume":"36 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140229051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Navigating Disclosure Obstacles Encountered by Individuals with HIV at Kakomo Healing Centre IV in Kabale District","authors":"Ahimbisibwe Godfrey","doi":"10.59298/idosr/jbbaf/23/13.4322","DOIUrl":"https://doi.org/10.59298/idosr/jbbaf/23/13.4322","url":null,"abstract":"HIV/AIDS remains a pressing global health concern, particularly impacting socio-economic development in various African nations, Uganda included. Revealing one's HIV-positive status to a family member or relative is crucial for adherence to effective antiretroviral therapy, which significantly enhances the survival and well-being of those living with HIV. To evaluate the hurdles faced by individuals with HIV at Kakomo HC IV in Kabale District regarding disclosure and to curtail new infections in this community, a descriptive crosssectional study was conducted. The study sampled individuals living with HIV at Kakomo HC IV randomly, utilizing a pretested questionnaire as the data collection instrument. The gathered data underwent coding, sorting, entry, and analysis through statistical software (SPSS), presented via tables and charts. Findings revealed that only 40 (50.6%) were adequately prepared before disclosing their status, while 30 (37.0%) neither prepared nor disclosed to anyone. 61 (63.5%) received education on the importance of disclosure during clinic visits, but 26 (46.4%) neither disclosed nor received such education. Barriers to disclosure primarily stemmed from anxiety about blame, stigma, fear of losing a partner, and violence among 18 (54.5%), 19 (52.8%), 30 (39.0%), and 2 (18.2%) individuals, respectively. Despite 62 (43.4%) intending to disclose to someone, 88 (98.9%) faced barriers to disclosing their status. Misconceptions in 51 (31.9%) communities and potential discrimination by families in the same proportion highlighted the challenges. Consequently, 123 (76.9%) still fear others spreading word of their HIV-positive status. Understanding disclosure motivations is crucial, requiring tailored strategies for decisionmaking based on the discloser's needs and their intended audience. The significance of support, proximity, and relational dynamics between the discloser and the recipient emphasizes the necessity for a secure environment during disclosure. Keywords: HIV/AIDS, Antiretroviral therapy, HIV-positive, HIV status, Stigma.","PeriodicalId":236427,"journal":{"name":"IDOSR JOURNAL OF BIOCHEMISTRY, BIOTECHNOLOGY AND ALLIED FIELDS","volume":"79 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139130524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Blood Transfusion Service Challenges and Patterns at Kampala International University Teaching Hospital, Ishaka-Bushenyi, Western Uganda: Insights from a Comprehensive Prospective Study","authors":"Bamwesigye Sanon","doi":"10.59298/idosr/jbbaf/23/11.1111","DOIUrl":"https://doi.org/10.59298/idosr/jbbaf/23/11.1111","url":null,"abstract":"Uganda, a developing East African nation with nearly 20% of its populace living below the poverty line, faces significant constraints in its national blood transfusion service. Despite serving over 3 million individuals in Regional Referral Hospitals, a chronic scarcity of blood persists, impacting critical healthcare provisions, notably at Mulago, Uganda’s National Referral Hospital. This study conducted a meticulous assessment of the indications and influential factors shaping blood transfusion services at Kampala International University Teaching Hospital, Ishaka-Bushenyi, adopting a prospective descriptive cross-sectional design encompassing a 100% review of the target patient population receiving blood transfusions. Employing a pretested questionnaire as the data collection instrument, the gathered information underwent meticulous coding, sorting, entry, and analysis utilizing statistical software. Results were systematically presented through tables and charts. The findings revealed that a considerable proportion (42.3%) of transfused individuals fell within the age range of 20-39 years, with infants and young children (<5 years) comprising 22.4% of the recipients. Males accounted for 58.7% of the transfused population. Predominant indications for blood transfusions included anemia (30.4%), obstetric and gynecological conditions (23.4%), surgical operations (19.0%), infections (14.2%), and incidents involving road traffic accidents or assault (13.0%). The study identified the availability of a blood storage facility as a significant factor motivating the utilization of blood transfusion services, with an 87.4% availability rate reported. Notably, the demand for transfusions was notably high among females (56.1%) compared to males (43.9%), with anemia (53.3%) and blood group O (48.6%) constituting the majority of cases. Blood group distributions varied across different indications, with group O being predominant in most categories. Additionally, the Rh factor played a role, with Rh+ constituting 90.5% of cases and Rh- comprising 9.5%. Blood Group O had the highest occurrence of Rh+, while Blood Group A had the highest occurrence of Rh-. In summary, the study outlined several prominent factors influencing blood transfusion indications at KIUTH, notably anemia, obstetric and gynecological conditions such as postpartum hemorrhage and cesarean sections, surgical procedures (e.g., abdominal obstructions), infections (e.g., malaria), and incidents involving road traffic accidents or assault. These indicators are influenced by factors such as blood availability, age, gender, medical conditions, and blood type, with Blood Group O Rh+ being the most prevalent. Keywords: Blood transfusion, Gynaecology, Anaemia, Blood Group O.","PeriodicalId":236427,"journal":{"name":"IDOSR JOURNAL OF BIOCHEMISTRY, BIOTECHNOLOGY AND ALLIED FIELDS","volume":"69 20","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139130701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comprehensive Assessment of Exclusive Breastfeeding: Insights into Knowledge, Attitude, and Practice among Lactating Mothers at Hoima Regional Referral Hospital, Hoima District: A High-Impact Analysis","authors":"Agaba Deusdedit","doi":"10.59298/idosr/jbbaf/23/12.2311","DOIUrl":"https://doi.org/10.59298/idosr/jbbaf/23/12.2311","url":null,"abstract":"This research aimed to rigorously evaluate the knowledge, attitude, and practice concerning exclusive breastfeeding among lactating mothers attending Hoima Regional Referral Hospital (HRRH). Employing a quantitative descriptive research design, the study meticulously selected mothers seeking medical attention for their infants at HRRH, adhering to rigorous selection criteria. A sample size of 208 subjects participated, comprising lactating mothers with infants aged between 0-6 months, utilizing a self-administered structured questionnaire to gather comprehensive data on exclusive breastfeeding behaviors. The data collected underwent meticulous analysis utilizing Statistical Analysis Software (STATA) version 10. Results revealed that a majority of the participants were aged between 25-29 years (30.8%) and had attained secondary education (38.5%), with an employment status predominantly as employed individuals or peasants (38.5%). The study cohort primarily resided in urban areas. Among the 208 lactating mothers, a significant proportion (61.5%) initiated breastfeeding within the first hour after birth, with the mode of delivery significantly influencing this initiation, favoring normal deliveries. However, the practice of exclusive breastfeeding exhibited a decline over subsequent months. Assessment of knowledge demonstrated that over 80% of mothers possessed substantial knowledge regarding exclusive breastfeeding, with a small percentage (5%) exhibiting poor knowledge. In terms of attitude, 74.4% expressed comfort and acknowledged exclusive breastfeeding as superior to artificial feeding, yet 40.9% reported feelings of shyness while breastfeeding. Interestingly, a positive correlation between higher education levels and a favorable attitude toward exclusive breastfeeding was observed. Overall, the study revealed a generally commendable level of knowledge, attitude, and practice concerning exclusive breastfeeding among lactating mothers attending Hoima Regional Referral Hospital. However, a notable finding was the significant decline in exclusive breastfeeding prevalence observed from the first month following initiation. Keywords: Exclusive breastfeeding, Breast milk, Infants, Lactating mothers.","PeriodicalId":236427,"journal":{"name":"IDOSR JOURNAL OF BIOCHEMISTRY, BIOTECHNOLOGY AND ALLIED FIELDS","volume":"102 39","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139133622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characteristics Linked to Severe Malaria in Under Five Years Old Children at Hoima Regional Referral Hospital, Hoima District","authors":"Logiel Deogratias Emuron","doi":"10.59298/idosr/jbbaf/23/17.8756","DOIUrl":"https://doi.org/10.59298/idosr/jbbaf/23/17.8756","url":null,"abstract":"This research aimed to identify the factors associated with severe malaria in children below five years old at Hoima Regional Referral Hospital in Hoima District. The study employed a cross-sectional approach, gathering both qualitative and quantitative data via participant self-administered and investigator-administered questionnaires. A sample of 384 children, aged 6 months to 4 years, participated using convenience sampling. The findings, presented with 95% Confidence Intervals (C.I), Odds Ratios (OR), and P-values, were calculated using Binary Logistic Regression with Pearson’s correlation in Statistical Package for Social Sciences (SPSS) Version 26. Visual representation utilized Microsoft Excel Software. The study had a response rate of 91.4%, encompassing 351 respondents, among whom 153 (43.6%) were male and 198 (56.4%) were female. The mean age was 2 years (with a standard deviation of 1.25 years). The malaria prevalence among these children attending HRRH was 27.4%. This prevalence was significantly linked to several factors: health serviceseeking behavior, caretaker’s education level, mosquito net usage, child’s age, and caretaker’s occupation, all exhibiting considerable influence on malaria in children under five. Pearson’s correlation indicated the significance of these variables: health serviceseeking behavior (0.139*, P=0.021), mosquito net use (0.286*, P=0.000), and health serviceseeking behavior (0.131*, P=0.021) with a 2-tailed test at a 95% confidence level, P<0.05. The high prevalence of malaria (27.4%) among children attending HRRH in Hoima District is notably affected by health service-seeking behavior, mosquito net usage, caretaker’s education, caretaker’s occupation, and the child’s age. Keywords: Malaria, children less than 5 years, Mosquito, Caretaker, Health service-seeking behaviour.","PeriodicalId":236427,"journal":{"name":"IDOSR JOURNAL OF BIOCHEMISTRY, BIOTECHNOLOGY AND ALLIED FIELDS","volume":"120 49","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139134840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"HIV Sero-Status and Risk Factors of Sero-Positivity of HIV Exposed Children Below Two Years of Age at Mityana General Hospital in Mityana District, Uganda","authors":"Lubuye Denis Senyonga","doi":"10.59298/idosr/jbbaf/23/18.5796","DOIUrl":"https://doi.org/10.59298/idosr/jbbaf/23/18.5796","url":null,"abstract":"The aim of this study was to identify the factors linked to HIV serostatus and the risks of HIV positivity among children under two years old exposed to HIV at Mityana General Hospital in Mityana district, Uganda. This was a cross-sectional descriptive survey utilizing quantitative data from administered questionnaires and routine service data obtained from the mother’s HIV care card and the exposed infant clinical chart. Data analysis was performed using Epi Info version 7.2.4 for entry and Stata version 16 for analysis. Descriptive statistics characterized both infant and mother traits. Logistic regression was employed to determine the factors associated with HIV serostatus. Among the 102 mother–infant pairs recruited, most mothers were between 25–34 years old (53/102, 52.0%), married (67/102, 65.7%), had attained at least primary education (49/102, 48.1%), and were involved in farming for their livelihood (89/102, 87.3%). The HIV prevalence among the infants stood at 8.8%. In the bivariate analysis, factors such as place of delivery (OR = 4.6, 95% CI: 1.340-9.413, p = 0.003), normal delivery (OR = 4.7, 95% CI:0.682-5.522, p= <0.001), poor adherence to ART (OR=3.11, 95% CI: 0.983-8.344, p=0.026), and the mothers’ level of education (OR=6.2, 95% CI: 3.00-14.476, p= <0.001) were associated with HIV-positive outcomes in infants below two years old. This study underscores that 8.8% of children under 2 years attending Mityana General Hospital are HIV-infected due to exposure from their mothers. Factors contributing to this burden include maternal non-adherence to ART, delivery in facilities lacking PMTCT protocols, maternal education levels, and the absence of prophylaxis administration to exposed infants, collectively propagating HIV transmission among these infants. Keywords: Pediatric HIV, Mother-to-child transmission, HIV serostatus, Infants below 2 years.","PeriodicalId":236427,"journal":{"name":"IDOSR JOURNAL OF BIOCHEMISTRY, BIOTECHNOLOGY AND ALLIED FIELDS","volume":" 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139135981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determining the Frequency and Influential Factors Impacting Antenatal Care Service Utilization Among Pregnant Women in Attendance at Mutara Health Centre III, Mitooma District, Uganda","authors":"Byaruhanga Aloysious Gonz","doi":"10.59298/idosr/jbbaf/23/15.6331","DOIUrl":"https://doi.org/10.59298/idosr/jbbaf/23/15.6331","url":null,"abstract":"Antenatal care (ANC) plays a pivotal role in curbing maternal mortality rates. This investigation sought to gauge the prevalence of and factors influencing antenatal care service utilization among pregnant women visiting Mutara Health Centre III's antenatal care clinic. The study involved 200 pregnant women in a cross-sectional analysis, employing an interview questionnaire to assess ANC service utilization determinants. Statistical Package for Social Sciences software was utilized for data analysis. The prevalence was determined by comparing the actual ANC attendance (from mid-July 2022 to mid-August 2022) against the projected monthly ANC attendance (300). The resulting attendance rate of 66.67% was categorized as inadequate, falling below the globally recommended coverage of 80%. Demographic findings revealed that the majority (57.5%) were peasants, while 47.5% of their partners had primary education. Alarmingly, 62.5% lacked knowledge regarding the appropriate timing for seeking ANC. Key conclusions drawn were that the attendance rate for ANC was notably low, coupled with inadequate knowledge among pregnant women about ANC and a prevalence of low socioeconomic status. Recommendations included tailored education programs for expectant mothers on ANC services by healthcare personnel at Mutara Health Centre III, public awareness campaigns by the Mitooma district health officer emphasizing the benefits of ANC attendance, governmental strategies to improve the livelihoods of those served by the health center, and a proposed study to assess maternal mortality prevalence specifically at Mutara Health Centre III. Keywords: Antenatal care, Pregnant women, maternal mortality, Healthcare workers.","PeriodicalId":236427,"journal":{"name":"IDOSR JOURNAL OF BIOCHEMISTRY, BIOTECHNOLOGY AND ALLIED FIELDS","volume":"16 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139129950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}