Nooshin Zeinali, J. Sebek, Hojjatollah Fallahi, Austin Pfannenstiel, P. Prakash
{"title":"Electromagnetic Transmission Coefficient-Based Assessment of Tissue State During Microwave Ablation","authors":"Nooshin Zeinali, J. Sebek, Hojjatollah Fallahi, Austin Pfannenstiel, P. Prakash","doi":"10.1115/dmd2022-1037","DOIUrl":"https://doi.org/10.1115/dmd2022-1037","url":null,"abstract":"\u0000 Background: During microwave ablation (MWA), applicators are positioned within/around the target under image guidance, however, real-time monitoring of the ablation zone growth is limited. The tissue dielectric properties change with increasing temperature; therefore, changes in the complex-valued electromagnetic transmission coefficient (s21) between applicators may provide a parameter for ablation monitoring.\u0000 Objective: To relate the physical state of tissue to the energy transmitted between a pair of directional MWA applicators.\u0000 Method: We implemented a method for sequential measurement of broadband s21 between two directional MWA applicators operating at 2.45GHz. In each experiment, the input of each applicator was periodically switched between a microwave generator (“heating mode”) and a vector network analyzer (VNA, “monitoring mode”). S-parameters and tissue images after ablation were collected from 19 experiments in fresh ex vivo liver tissue for heating times 53-1200s. From gathered s21, we computed the average transmission coefficient (ATC) and group delay (GD) and related them to tissue state.\u0000 Results: Both ATC and GD decrease with time and saturate towards the completion of ablation at ~75% and ~96% of the initial value respectively.\u0000 Conclusion: We demonstrated the potential of in-procedure tissue state assessment by monitoring s21 between two directional MWA applicators in ex vivo liver.","PeriodicalId":236105,"journal":{"name":"2022 Design of Medical Devices Conference","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132535772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Development of an Automated Transcutaneous Electrical Acustimulation Device Synchronized with Respiration for Treating Gastroesophageal Reflux Diseases","authors":"Jinsai Cheng, G. Song, Qiang Guan, T. Shen","doi":"10.1115/dmd2022-1012","DOIUrl":"https://doi.org/10.1115/dmd2022-1012","url":null,"abstract":"\u0000 Gastroesophageal reflux disease (GERD) is a common digestive disorder that usually has symptoms including reflux, heartburn, pain when swallowing, etc. Evolving from traditional needle acupuncture and electroacupuncture (EA), transcutaneous electrical acustimulation (TEA) becomes a popular method for treating GERD with its non-invasive intervention feature. Recently, an even more effective method synchronized with respiration in TEA is emerging. However, the current procedure for conducting synchronized TEA (STEA) treatment is mostly based on patients’ manual synchronization, which can generate a big delay or error in the synchronization, significantly compromising the effectiveness of this method. To solve this issue, this research presents a novel STEA device that can automatically detect the user’s respiration wave and synchronize with the breath to conduct TEA. With this automated synchronization device, the patients can inhale and exhale with an uninterrupted and normal respiration pace while receiving the TEA treatment, largely simplifying the treatment procedures and enhancing the effectiveness of the method. The system of the STEA device consists of a chest strip respiration sensing element, a stimulation point identifier, and a stimulation current generator. Experiments were conducted to verify human respiration detection, electrical current generation and synchronization. The results demonstrated the feasibility, effectiveness and reliability of the automated device system.","PeriodicalId":236105,"journal":{"name":"2022 Design of Medical Devices Conference","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134222117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Patient-Centered Hospital Gowns: A Novel Redesign of Inpatient Attire to Improve Both the Patient and Provider Experience","authors":"Priya Arunachalam, Brendan D’Souza","doi":"10.1115/dmd2022-1058","DOIUrl":"https://doi.org/10.1115/dmd2022-1058","url":null,"abstract":"\u0000 During their inpatient stays, patients are often required – or highly encouraged – to wear hospital gowns. While these gowns are intended to be convenient for patients and their providers, their design has remained largely unchanged over time. As healthcare moves towards greater emphasis on patient-centered care, the hospital gown is an opportunity to improve patient care. Patients have expressed frustration with the traditional hospital gown, especially with how revealing the gown can be. Here, we introduce a redesigned hospital gown that addresses many common concerns related to patients’ comfort and privacy. Our design introduces novel midline, rear, and shoulder panels, which provide healthcare workers with convenient access to the patient while maintaining coverage over areas of the patient that are not being examined. These panels also make it less likely for patients to be inappropriately exposed during routine activities. A prototyped gown was developed to test design features, and evaluation of this prototype demonstrated that this novel design has the potential to address many concerns while protecting the usability of traditional gowns. Further improvements to the gown’s design are also discussed.","PeriodicalId":236105,"journal":{"name":"2022 Design of Medical Devices Conference","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131410780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Aberrant Coronary Artery: A Rare Congenital Anomaly Examined Through Pre- And Post-Procedural 3D Anatomical Modeling","authors":"Amanda Tenhoff, T. Iles, P. Iaizzo, R. MacIver","doi":"10.1115/dmd2022-1061","DOIUrl":"https://doi.org/10.1115/dmd2022-1061","url":null,"abstract":"\u0000 Congenital heart disease – structural abnormalities of the heart that are present at and persistent beyond birth – affects about one in every 100 live births every year in the United States [1]. One such disease is that of the aberrant coronary artery, which describes abnormalities of coronary artery morphology. In our case, we examine a patient exhibiting complex aberrant right coronary artery – a rare congenital heart defect. Pre- and post-procedural imaging was acquired from this case, and subsequent three-dimensional (3D) anatomical models were created. These models were used postoperatively to identify and describe the patient’s disease presentation for the purposes of research and education, and were incorporated into virtual reality (VR) scenes in order to further educational insights.","PeriodicalId":236105,"journal":{"name":"2022 Design of Medical Devices Conference","volume":"209 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114758060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Design and Development of Novel Anatomical Scapular Fracture Fixation Plates: Population-Based and Fracture-Focused Design","authors":"Habtamu M. Yimam, R. Dey, S. Roche, S. Sivarasu","doi":"10.1115/dmd2022-1027","DOIUrl":"https://doi.org/10.1115/dmd2022-1027","url":null,"abstract":"\u0000 Surgical fixation is a recommended procedure for displaced and unstable scapular fractures to restore anatomical alignment and articular congruency of the fracture fragments. Anatomically Precontoured scapular plates are designed to guide the fracture reduction, used as a template, and stabilize the fixation. However, anatomical variation of the scapula and the complexity of the fracture patterns limit the usability of these plates. The aim of this study was to design and develop population-based novel anatomical scapular plates. An average three-dimensional (3D) scapular bone model was developed from 22 healthy cadaver scapulae of target population (South Africans) using Statistical Shape Modelling (SSM) method. The fracture region of interests was identified using a fracture map of 70 scapular fracture patterns. Using the average 3D scapular model as a reference template and the common fracture zones as a reference fracture pattern, anatomical plates were designed for the critical scapula fracture patterns. Lateral border, medial border, glenoid fossa & neck, glenoid fossa & body, and acromion plates were designed. Combining 3D CT image based statistical shape modelling and fracture pattern analysis with CAD is relatively quick and efficient method to develop clinically meaningful population-based anatomical plates.","PeriodicalId":236105,"journal":{"name":"2022 Design of Medical Devices Conference","volume":"148 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123493812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ana Delgado, Pengfei Dong, Mahyar Sameti, V. Zimin, Juhwan Lee, Y. Gharaibeh, H. Bezerra, D. Wilson, C. Bashur, L. Gu
{"title":"Mechanical Characterization of Calcificaiton in Diseased Coronary Artery with Atomic Force Microscope","authors":"Ana Delgado, Pengfei Dong, Mahyar Sameti, V. Zimin, Juhwan Lee, Y. Gharaibeh, H. Bezerra, D. Wilson, C. Bashur, L. Gu","doi":"10.1115/dmd2022-1055","DOIUrl":"https://doi.org/10.1115/dmd2022-1055","url":null,"abstract":"\u0000 In this work, the mechanical propertied of calcification in diseased coronary artery was evaluated with atomic force microscope (AFM). The heavily calcified coronary artery was harvest from a cadaver’s heart. The artery slices with thickness of 10 um were prepared with cryosectioning. Staining with Alizarin Red has been performed to highlight the calcification region. Results have shown that the calcified areas have a significant larger stiffness compared with the surrounding plaque and the media layer of a healthy artery. The calcification showed a heterogeneous property with larger deviation in stiffness distribution. The staining process affected the mechanical properties. Results will enhance the mechanical property database in the literature.","PeriodicalId":236105,"journal":{"name":"2022 Design of Medical Devices Conference","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128593415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Low-Cost and Easy-to-Use Laser Corneal Reshaping Device for Educational, Research and Training Purposes","authors":"Ibrahim Abdelhalim, Omnia Hamdy","doi":"10.1115/dmd2022-1009","DOIUrl":"https://doi.org/10.1115/dmd2022-1009","url":null,"abstract":"\u0000 Recently, many vision disorders such as myopia and hyperopia can be corrected via LASIK refractive surgery. Based on the photo-ablation effect of UV-laser pulses (at 193 nm for most commercial devices), the shape of the treated cornea is modified in order to regain the normal vision capability. In laser corneal reshaping process, the laser parameters must be adjusted to maintain the desired photo-ablation effect. Moreover, the design of the employed device plays an important role in performing successful surgeries with optimum results. However, the commercial devices are designed for specific operations with a limited access to their optical system and software. Besides, these devices are not available for research or training. Consequently, we provide a low-cost and easy-to-use ablation device that can be utilized as an educational, research, and training tool for the specialists in corneal reshaping and related procedures at universities, research institutes, or medical centers. The device has a special opening to enable entry of external laser source for any desired experimental investigations. Moreover, the binocular in commercial devices is replaced by live view screen to decrease the device’s cost. There are no access limitations to the software or the optical system of the proposed device.","PeriodicalId":236105,"journal":{"name":"2022 Design of Medical Devices Conference","volume":"69 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128599259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Optimization of Small-Scale Hydraulic Structures for Powered Exoskeletons","authors":"Jeffrey J. Bies, W. Durfee","doi":"10.1115/dmd2022-1036","DOIUrl":"https://doi.org/10.1115/dmd2022-1036","url":null,"abstract":"\u0000 Generative design is an optimization process that is well-suited for various applications in fluid power, including untethered assistive technology exoskeletons powered through hydraulics. While generative design is capable of improving factors such as efficiency, system weight, and surface temperatures, there are currently no solutions that can address these factors simultaneously. The long-range goal of this research is to develop a multiphysics generative design process that combines solid mechanics, fluid mechanics, and heat transfer into a single algorithm to produce designs for high-pressure hydraulic systems that also provide structural support against external loads and passive cooling all in a single integrated structure. To create a generative design algorithm, a Python pipeline was constructed to interface with existing software applications to iterate through geometry creation, meshing, finite volume method, and sensitivity analysis. The pipeline was validated using a simplified case study of pressurized fluid flow through a pipe with a 90-degree bend where the flow path was modified between a fixed inlet and outlet to reduce pressure drop by 37.2±0.4%, corresponding directly to a reduction in battery size and, therefore, system weight. Future work will use multiphysics sensitivity analysis and machine learning to inform the iterative geometry refinement.","PeriodicalId":236105,"journal":{"name":"2022 Design of Medical Devices Conference","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130729686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rasika Thombre, Griffin Mess, Eli Curry, R. Mejía, Fariba Aghabaglou, Max J. Kerensky, Haley G. Abramson, Roslyn VanSickle, B. Tyler, N. Theodore, A. Manbachi
{"title":"Design and Development of System Components for Therapeutic Ultrasound Devices: Enhancing Focused Ultrasound Treatments Using Cones with Clinical and Ergonomic Considerations","authors":"Rasika Thombre, Griffin Mess, Eli Curry, R. Mejía, Fariba Aghabaglou, Max J. Kerensky, Haley G. Abramson, Roslyn VanSickle, B. Tyler, N. Theodore, A. Manbachi","doi":"10.1115/dmd2022-1030","DOIUrl":"https://doi.org/10.1115/dmd2022-1030","url":null,"abstract":"\u0000 Focused ultrasound (FUS) is an emerging technique with the potential to revolutionize traditional treatment methods in the fields of oncology and neurosurgery. Recently, FUS treatments have shown potential for altering neural activity in the spinal cord, with the intent to alleviate pain. Preliminary animal studies using FUS have demonstrated the need for transducer accessories that can simplify the implementation of the transducer in the clinic. The coupling cone that was supplied with the transducer was designed for larger target tissues. Thus, surgeons have expressed a desire to adapt the cone design to be easier to use for smaller targets, such as the spinal cord. Here, we developed 3D printed cones, with smaller aperture sizes, for FUS transducers to assist surgeons in localizing the focal point of the transducers in a faster, and more intuitive manner. The cones were designed to not alter the original focal region of the transducers. This was experimentally confirmed by measuring the size of the focal region for the transducer with the new cones and comparing this data to measurements provided by the manufacturer. The new coupling cones will make the FUS transducers more ergonomic for use in stimulating the spinal cord in an animal model.","PeriodicalId":236105,"journal":{"name":"2022 Design of Medical Devices Conference","volume":"116 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132410412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Finite Element Modeling Using Patient-Specific Geometry to Predict Aortic Valve Insufficiency During Percutaneous Pulmonary Valve Implantation","authors":"Carly L. Donahue, V. Aggarwal, V. Barocas","doi":"10.1115/dmd2022-1022","DOIUrl":"https://doi.org/10.1115/dmd2022-1022","url":null,"abstract":"\u0000 Percutaneous pulmonary valve implantation (PPVI) is a non-surgical treatment in which a stented valve is delivered via catheter to replace a stenosed or leaky pulmonary valve. Stent oversizing is used to anchor the valve within the right ventricular outflow tract (RVOT), but overexpansion may interfere with adjoining structures specifically the aortic root and coronary arteries. Potential devastating consequences include distortion of the aortic sinus, causing aortic valve insufficiency, and/or compression of the coronary arteries. Because the outcome of PPVI is determined by the patient’s anatomy, we propose a method that uses patient-specific finite-element (FE) models constructed from pre-procedural cross-sectional CT scan images to evaluate these potential risks prior to clinical intervention. In five cases from an ongoing retrospective study, our preliminary results demonstrate our model’s ability to accurately identify the risk of aortic valve insufficiency as a consequence of the PPVI procedure.","PeriodicalId":236105,"journal":{"name":"2022 Design of Medical Devices Conference","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130805384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}