Veterinary RecordPub Date : 2025-03-01Epub Date: 2024-12-27DOI: 10.1002/vetr.4962
Pavlos Natsios, Lorenzo Golini, Brian H Park, Frank Steffen
{"title":"Effect of local epidural application of methylprednisolone acetate on time to ambulation in non-ambulatory dogs with thoracolumbar intervertebral disc disease: A prospective randomised, blinded control trial.","authors":"Pavlos Natsios, Lorenzo Golini, Brian H Park, Frank Steffen","doi":"10.1002/vetr.4962","DOIUrl":"10.1002/vetr.4962","url":null,"abstract":"<p><strong>Background: </strong>The objective of this study was to analyse the potential benefit of the epidural application of steroids on time to ambulation in non-ambulatory dogs affected by intervertebral disc disease (IVDD) treated with decompressive surgery.</p><p><strong>Methods: </strong>This prospective, randomised, blinded control trial involved 41 dogs with thoracolumbar disc extrusion, which were randomly allocated into two groups. In the control group, saline was locally applied after surgical decompression of the spinal cord (n = 23). In the treatment group (n = 18), local epidural application of methylprednisolone acetate (1 mg/kg) was used. Ambulation time was the primary outcome measure, defined as the ability to take 10 independent steps.</p><p><strong>Results: </strong>The median number of days to ambulation was 7 days (range: 1‒17 days) for the control group and 3 days (range: 1‒8 days) for the treatment group. One dog from the treatment group developed discospondylitis and abscess formation.</p><p><strong>Limitations: </strong>The study's heterogeneity in dog breeds, ages and pre-existing health conditions could affect the generalisability of the findings.</p><p><strong>Conclusion: </strong>Epidural methylprednisolone acetate applied locally at the time of surgery may accelerate recovery in dogs following IVDD surgery.</p>","PeriodicalId":23560,"journal":{"name":"Veterinary Record","volume":" ","pages":"e4962"},"PeriodicalIF":1.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11869356/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142898471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Help shape the future of animal welfare.","authors":"","doi":"10.1002/vetr.5311","DOIUrl":"https://doi.org/10.1002/vetr.5311","url":null,"abstract":"","PeriodicalId":23560,"journal":{"name":"Veterinary Record","volume":"196 5","pages":"204"},"PeriodicalIF":1.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143524626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Disease surveillance in England and Wales, February 2025.","authors":"","doi":"10.1002/vetr.5290","DOIUrl":"https://doi.org/10.1002/vetr.5290","url":null,"abstract":"","PeriodicalId":23560,"journal":{"name":"Veterinary Record","volume":"196 5","pages":"178-183"},"PeriodicalIF":1.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143524654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Message from the President.","authors":"Liz Mullineaux","doi":"10.1002/vetr.5309","DOIUrl":"https://doi.org/10.1002/vetr.5309","url":null,"abstract":"<p><p>With International Women's Day being celebrated on 8 March this year, Liz Mullineaux reflects on how things have - and have not - changed for women in the profession in recent decades.</p>","PeriodicalId":23560,"journal":{"name":"Veterinary Record","volume":"196 5","pages":"203"},"PeriodicalIF":1.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143524673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alexander J German, Georgiana Woods, Ernie Ward, Julie Churchill
{"title":"'We should adopt new definitions for clinical obesity in companion animals'.","authors":"Alexander J German, Georgiana Woods, Ernie Ward, Julie Churchill","doi":"10.1002/vetr.5300","DOIUrl":"https://doi.org/10.1002/vetr.5300","url":null,"abstract":"<p><p>Alex German, Georgiana Woods, Ernie Ward and Julie Churchill explain that in human medicine new, clearer definitions for obesity have been adopted. They propose that similar definitions should be taken on in companion animal practice and urge the veterinary profession to consider these.</p>","PeriodicalId":23560,"journal":{"name":"Veterinary Record","volume":"196 5","pages":"197-198"},"PeriodicalIF":1.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143524713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Using the epidural route for more targeted delivery of therapeutics in dogs with spinal cord injury.","authors":"Sergio A Gomes","doi":"10.1002/vetr.5291","DOIUrl":"https://doi.org/10.1002/vetr.5291","url":null,"abstract":"","PeriodicalId":23560,"journal":{"name":"Veterinary Record","volume":"196 5","pages":"185-187"},"PeriodicalIF":1.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143524706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Future of greyhound racing in Wales.","authors":"","doi":"10.1002/vetr.5304","DOIUrl":"https://doi.org/10.1002/vetr.5304","url":null,"abstract":"","PeriodicalId":23560,"journal":{"name":"Veterinary Record","volume":"196 5","pages":"201"},"PeriodicalIF":1.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143524623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}