VascularPub Date : 2025-08-01Epub Date: 2024-06-24DOI: 10.1177/17085381241262919
Bilal Masood, Hamza Akhtar, Junaid Khan, Shuah Ullah Mir, Tanzeel Ur Rehman, Yasir Sindhi, Abdirasak Ahmed, Bux Ali, Ziad Sophie
{"title":"To evaluate the complication and patency rate of superficial femoral vein transposition in tertiary care center.","authors":"Bilal Masood, Hamza Akhtar, Junaid Khan, Shuah Ullah Mir, Tanzeel Ur Rehman, Yasir Sindhi, Abdirasak Ahmed, Bux Ali, Ziad Sophie","doi":"10.1177/17085381241262919","DOIUrl":"10.1177/17085381241262919","url":null,"abstract":"<p><p>IntroductionWhen all access options in the upper extremity have been exhausted, an autologous access can be created in lower extremity. The purpose of this study is to report our experience with superficial femoral vein transposition (SFVT) results in terms of postoperative complication and patency rate.Materials and MethodsIn the time period from January 1, 2019 to April 30, 2021, thirty-five cases of SFVT performed at our large tertiary care center Sindh Institute of Urology and Transplantation (SIUT). All patients had exhausted upper arm veins or had central vein obstructions. Medical records of all patients were traced, patients were interviewed using a standard proforma and evaluated the current AVF function in the OPD clinic or by telephone calls. Data including demographics and postoperative complications were collected.ResultsThirty-nine cases of SFVT performed at our institute. Three were immediately lost to follow up so they were excluded from the study. Mean patient age was 30 ± 13.4 years. Most of our patients were females (57%) and 15 males (43%) with an average age of 29.05 years. The most common underlying renal diseasewas unknown in 16 (45%).Thirty-five patients included in the analysis; out of which primary failure observed in 4 patients, three patients were expired before fistula maturation and 3 were expired before 6 months. The remaining 25 fistulas patency rates were estimated. No any patient died due to fistulas related complication; patients died due to their primary disease.ConclusionOur study shows that with appropriate patient selection, SFVT have low infection rates and patency that is comparable with other access types.</p>","PeriodicalId":23549,"journal":{"name":"Vascular","volume":" ","pages":"886-892"},"PeriodicalIF":0.9,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141443398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
VascularPub Date : 2025-08-01Epub Date: 2024-06-21DOI: 10.1177/17085381241261752
Sang Su Lee, Hyo Won Park, Min Soo Kim, Jeong Eun Sohn, Dae Hwan Kim, Kilsoo Yie
{"title":"A protocolized five strategies in open repair for ruptured abdominal aortic aneurysm.","authors":"Sang Su Lee, Hyo Won Park, Min Soo Kim, Jeong Eun Sohn, Dae Hwan Kim, Kilsoo Yie","doi":"10.1177/17085381241261752","DOIUrl":"10.1177/17085381241261752","url":null,"abstract":"<p><p>ObjectivesAlthough the medical field has made significant progress, there has been little improvement in the survival rate of patients with ruptured abdominal aortic aneurysms (rAAAs). We implemented a protocol consisting of five strategies in the management of rAAA patients who underwent open repair surgery.MethodsThe protocol comprised the following strategies: intentional hypotension <70 mmHg, lung first and kidney last policy (restricted fluid resuscitation and permissive oligoanuria), immediate postoperative extubation, free-water intake with active ambulation, and open abdomen with the routine second-look operation. The study included 13 patients (11 male) with a mean age of 75.5 ± 7.4 (range: 58-87) years who underwent the procedure from 2016 to 2018, with a mean follow-up of 40.1 ± 9.04 months. Five deteriorating to hemodynamic shock and decreased consciousness requiring intubation and ventilation prior to surgery were observed. Two of these patients required preoperative cardiopulmonary resuscitation (CPR).ResultsAll patients regained consciousness after surgery, including the two patients who required cardiopulmonary resuscitation. Immediate postoperative extubation was performed in nine patients, but two (22.2%) of them needed re-intubation due to ventilation/perfusion mismatch. Four patients underwent continuous renal replacement therapy, with three of them having anuria for up to 48 h after surgery. Two of these patients made a full recovery. Daily ambulation was carried out for a mean of 4.77 ± 3.5 (range 1-13) days with an open abdomen, during which no significant events were reported. Four cases of colon ischemia/necrosis were identified in the second-look operation, with two patients requiring Hartman's procedure and the other two undergoing left colon partial resection. There were two in-hospital mortalities (15.4%).ConclusionsA protocol-based approach, through multidisciplinary team consensus and the development of optimal surgical strategies, could improve clinical outcomes for patients undergoing emergency surgery for rAAA. Further studies with larger sample sizes are needed to refine the protocols.</p>","PeriodicalId":23549,"journal":{"name":"Vascular","volume":" ","pages":"756-763"},"PeriodicalIF":0.9,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141437575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
VascularPub Date : 2025-08-01Epub Date: 2024-07-22DOI: 10.1177/17085381241265159
Hyo Kee Kim, Pyoung Jae Park, Jee Hyun Park, Young Ju Oh, Cheol Woong Jung, Heungman Jun
{"title":"Nationwide analysis of EVAR explantation outcomes in Korea: A comprehensive dataset study.","authors":"Hyo Kee Kim, Pyoung Jae Park, Jee Hyun Park, Young Ju Oh, Cheol Woong Jung, Heungman Jun","doi":"10.1177/17085381241265159","DOIUrl":"10.1177/17085381241265159","url":null,"abstract":"<p><p>ObjectiveEndovascular aortic aneurysm repair (EVAR) is the primary treatment for abdominal aortic aneurysms, constituting 70%-80% of interventions. Despite initial benefits, long-term studies show increased mortality. Using nationwide data, this study assesses outcomes of EVAR, open aortic repair (OAR), and EVAR explantation (EE) in Korea, while exploring characteristics of late open conversion, including the rising EE incidence.MethodsEmploying the National Health Insurance Service database, covering health-related data for nearly 50 million Koreans, the study spanned from 2002 to 2020. Patients with AAA diagnoses (I71.3 or I71.4) were categorized into OAR, EVAR, and EE groups based on procedural codes. Statistical analyses, including t-tests, Fisher's exact tests, Cox proportional hazard models, and multivariate Cox regression, assessed baseline characteristics, mortality risks, and factors within the EE group.ResultsThe analysis encompassed 26,195 patients, with 66.19% in the EVAR group, 31.87% in the OAR group, and 1.94% in the EE group. EVAR cases steadily increased from 2002 to 2018. Survival rates favored EVAR, followed by OAR and EE. 30-day survival was lower in EE than EVAR. Multivariate analysis for EE revealed no risk factors for 30-days survival but identified age, chronic kidney disease, high Charlson Comorbidity Index scores, and less than 6 months since EVAR as risk factors for overall mortality.ConclusionRising EE trends with increased EVAR adoption, particularly evident in the Korean dataset, underscore inferior outcomes. This highlights the critical need for strategic initial treatment decisions and timely interventions to enhance overall results and mitigate the unfavorable EE incidence.</p>","PeriodicalId":23549,"journal":{"name":"Vascular","volume":" ","pages":"790-795"},"PeriodicalIF":0.9,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141735081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Difference in right and left cardio-ankle vascular index as a useful marker for evaluation of leg ischemia in patients with lower extremity arterial disease.","authors":"Yoko Sotoda, Shigeki Hirooka, Hiroyuki Orita, Ichiro Wakabayashi","doi":"10.1177/17085381241263905","DOIUrl":"10.1177/17085381241263905","url":null,"abstract":"<p><p>ObjectivesCardio-ankle vascular index (CAVI) is a blood pressure-independent measure of heart-ankle pulse wave velocity and is used as an indicator of arterial stiffness. However, there is a paradox that CAVI is inversely associated with leg ischemia in patients with lower extremity arterial disease (LEAD). The aim of this study was to clarify the significance of the absolute value of left and right difference in CAVI (diff-CAVI).MethodsThe subjects were 165 patients with LEAD who had received medication therapy. Relationships between diff-CAVI and leg ischemia were investigated. Leg ischemia was evaluated by decrease in leg arterial flow using ankle-brachial index (ABI) and by symptoms using the Rutherford classification.ResultsThere was a significant inverse correlation between diff-CAVI and ABI. The odds ratio for low ABI of the 3rd versus 1st tertile groups of diff-CAVI was 7.03 with a 95% confidence interval of 2.71 ∼ 18.22. In ROC analysis, the cutoff value of diff-CAVI for low ABI was 1.05 with a sensitivity of 61.1% and a specificity of 87.1%. The median of diff-CAVI was significantly higher in subjects with grade 2 of the Rutherford classification than in subjects with its grade 1.Conclusionsdiff-CAVI showed an inverse association with ABI and a positive association with symptoms of leg ischemia. Thus, diff-CAVI is thought to be a useful indicator of leg ischemia in LEAD patients.</p>","PeriodicalId":23549,"journal":{"name":"Vascular","volume":" ","pages":"948-955"},"PeriodicalIF":0.9,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141735080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
VascularPub Date : 2025-08-01Epub Date: 2024-07-24DOI: 10.1177/17085381241264726
Renxi Li, Deyanira J Prastein
{"title":"Peripheral artery disease is an independent risk factor for higher in-hospital mortality in Stanford type A aortic dissection repair.","authors":"Renxi Li, Deyanira J Prastein","doi":"10.1177/17085381241264726","DOIUrl":"10.1177/17085381241264726","url":null,"abstract":"<p><p>BackgroundType A aortic dissection (TAAD) is an emergent condition that warrants immediate intervention. Peripheral artery disease (PAD) is a prevalent disease associated with worse outcomes in various cardiovascular procedures. However, it remains unclear whether PAD influences outcomes of TAAD repair. This study aimed to undertake a population-based analysis to assess impact of PAD on in-hospital outcomes following TAAD repair.MethodsPatients underwent TAAD repair were identified in National Inpatient Sample from Q4 2015 to 2020. Multivariable logistic regressions were used to compare in-hospital outcomes between patients with and without PAD, adjusted for demographics, socioeconomic status, primary payer status, hospital characteristics, comorbidities, and transfer/admission status.Results1525 patients with PAD and 2757 non-PAD patients underwent TAAD. PAD patients had higher mortality (18.62% vs 13.17%, aOR = 1.287, <i>p</i> = .01), AKI (51.41% vs 47.48%, aOR = 1.222, <i>p</i> < .01), infection (10.69% vs 8.02%, aOR = 1.269, <i>p</i> = .03), and vascular complication (7.28% vs 3.77%, aOR = 1.846, <i>p</i> < .01) but lower risks of pericardial complications (15.21% vs 19.95%, aOR = 0.696, <i>p</i> < .01). In addition, patients with PAD had longer time from admission to operation (1.29 ± 3.95 vs 0.70 ± 2.09 days, <i>p</i> < .01), longer LOS (14.92 ± 13.98 vs 13.41 ± 11.66 days, <i>p</i> = .01), and higher hospital charge (499,064 ± 519,405 vs 409,754 ± 405,663 US dollars, <i>p</i> < .01).ConclusionPAD was independently associated with worse outcome after TAAD repair. The elevated mortality rate could be attributed to the delay in surgery, which may be related to preoperative peripheral malperfusion syndrome that is common in PAD patients. A balance between preoperative management and immediate TAAD repair might be essential to prevent the increased mortality risk from treatment delays among PAD patients.</p>","PeriodicalId":23549,"journal":{"name":"Vascular","volume":" ","pages":"845-852"},"PeriodicalIF":0.9,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141752886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
VascularPub Date : 2025-08-01Epub Date: 2024-07-29DOI: 10.1177/17085381241269790
Renxi Li, Anton Sidawy, Bao-Ngoc Nguyen
{"title":"The association of chronic obstructive pulmonary disease and 30-day outcomes of infrainguinal bypass surgery: A propensity-score matching study.","authors":"Renxi Li, Anton Sidawy, Bao-Ngoc Nguyen","doi":"10.1177/17085381241269790","DOIUrl":"10.1177/17085381241269790","url":null,"abstract":"<p><p>BackgroundInfrainguinal bypass surgery is an effective treatment for peripheral artery disease (PAD). While chronic obstructive pulmonary disease (COPD) has been linked to heightened risks of mortality and morbidity in major surgery, a thorough investigation into COPD's impact on infrainguinal bypass outcomes remained underexplored. Thus, this study aimed to assess the 30-day outcomes for COPD patients undergoing infrainguinal bypass surgery.MethodsCOPD and non-COPD patients who underwent infrainguinal bypass were identified in American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) database from 2011 to 2022. Patients of age<18 were excluded. A 1:1 propensity-score matching was used to match demographics, baseline characteristics, symptomatology, procedure, conduit, and anesthesia. Thirty postoperative outcomes were compared.ResultsThere were 3,183 (12.64%) and 22,004 (87.36%) patients with and without COPD, respectively, who underwent infrainguinal bypass. COPD patients had a higher comorbid burden. After propensity-score matching, COPD patients had higher sepsis (3.55% vs 2.42%, <i>p</i> = 0.01), wound complications (18.94% vs 16.40%, <i>p</i> = 0.01), and 30-day readmission (18.00% vs 14.92%, <i>p</i> < 0.01). However, COPD and non-COPD patients had comparable 30-day mortality (2.54% vs 2.67%, <i>p</i> = 0.81), and organ system complications including cardiac (3.58% vs 3.99%, <i>p</i> = 0.43), pulmonary (3.96% vs 3.20%, <i>p</i> = 0.12), and renal complications (1.70% vs 1.82%, <i>p</i> = 0.78). Limb-specific outcomes including major amputation (2.95% vs 2.50%, <i>p</i> = 0.30), untreated loss of patency (1.85% vs 1.38%, <i>p</i> = 0.16), and patent graft (98.24% vs 98.65%, <i>p</i> = 0.27) were also comparable between the cohorts.ConclusionWhile COPD might be associated with the development of PAD due to potentially shared pathophysiology, it may not be an independent risk factor for the major 30-day outcomes in infrainguinal bypass surgery.</p>","PeriodicalId":23549,"journal":{"name":"Vascular","volume":" ","pages":"969-976"},"PeriodicalIF":0.9,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141793652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
VascularPub Date : 2025-08-01Epub Date: 2024-08-09DOI: 10.1177/17085381241273211
Nikita Singh, Tyler Santos, Ali Basil Ali, Hason Khan, Pavel Kibrik, Jason Storch, Halbert Bai, Mark Awad, Ronak Patel, Michael Huber, Enrico Ascher, Natalie Marks, Anil Hingorani
{"title":"Contraindications to tissue plasminogen activator thrombolysis for acute lower extremity ischemia.","authors":"Nikita Singh, Tyler Santos, Ali Basil Ali, Hason Khan, Pavel Kibrik, Jason Storch, Halbert Bai, Mark Awad, Ronak Patel, Michael Huber, Enrico Ascher, Natalie Marks, Anil Hingorani","doi":"10.1177/17085381241273211","DOIUrl":"10.1177/17085381241273211","url":null,"abstract":"<p><p>ObjectivePrevious randomized prospective trials have demonstrated the effectiveness of transcatheter tissue plasminogen activator (tPA) thrombolysis in treating acute limb ischemia (ALI) compared to conventional surgery. These pivotal trials have also highlighted contraindications for these procedures. Given recent advancements in techniques and technology, our aim is to reassess the relevance of these contraindications in contemporary practice.MethodsA retrospective chart analysis was performed utilizing the inpatient medical records of consecutive individuals who underwent tPA treatment for acute limb ischemia (ALI) from September 2016 to April 2022. Inclusion criteria encompassed patients aged 18 and above displaying clinical symptoms and imaging evidence of ALI within 14 days. All patients received tPA with suction thrombectomy following the fast-track thrombolysis protocol. In cases where a persistent thrombus or stenosis was detected, catheter-directed thrombolysis was considered overnight, and patients underwent angiography and reassessment in the operating room subsequently.ResultsPatients were classified into two groups based on the STILE trial's established contraindications for endovascular treatment in acute limb ischemia (ALI). If a patient had any of these contraindications, they were placed in the contraindicated group. This resulted in 24 patients (32%) in the contraindicated group and 52 patients (68%) in the non-contraindicated group. No statistically significant demographic variations were observed between these groups. Contraindications in our study included uncontrolled hypertension (12/24, 50%), recent invasive procedures (7/27, 29%), history of cerebrovascular accident (CVA) within 6 months (3/24, 12%), and intracranial malformation/neoplasms (2/24, 8%). Three patients within the non-contraindicated group experienced bleeding complications: two with puncture site bleeds and one with nasal bleeding. In contrast, one patient in the contraindicated group had transient postoperative hematuria. There were no significant differences in bleeding complications observed between the two groups (<i>p</i> = .771). Additionally, no amputations were observed within our population.ConclusionsIn light of our study results and advancements in endovascular therapies, we can now safely and efficiently treat patients who were previously considered contraindicated for such treatments. It is essential to individualize treatments and carefully balance the risks and benefits of endovascular versus open surgical revascularization for these patients. Additionally, we believe that the nearly 30-year-old guidelines for endovascular therapies need to be revisited and updated to align with modern technology.</p>","PeriodicalId":23549,"journal":{"name":"Vascular","volume":" ","pages":"962-968"},"PeriodicalIF":0.9,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141907803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
VascularPub Date : 2025-08-01Epub Date: 2024-07-21DOI: 10.1177/17085381241260910
Jakub Kwiecinski, Raman Uberoi, Mohammed Hadi, Christopher P Cheng, Zhong You
{"title":"<i>In vitro</i> quantification of stent-graft behaviour during chimney thoracic endovascular aortic repair.","authors":"Jakub Kwiecinski, Raman Uberoi, Mohammed Hadi, Christopher P Cheng, Zhong You","doi":"10.1177/17085381241260910","DOIUrl":"10.1177/17085381241260910","url":null,"abstract":"<p><p>ObjectiveTo quantify dynamic gutter phenomena and endograft deformations during double chimney thoracic endovascular aortic repair (ch-TEVAR) in a physiological model of the thoracic aorta subjected to pulsatile haemodynamic conditions.MethodsTwo <i>in vitro</i> procedures revascularizing the brachiocephalic trunk and left common carotid artery were performed representing both balloon-expandable (BE, Ankura-BeGraft) and self-expandable (SE, Ankura-Viabahn) double ch-TEVAR configurations. Retrospectively gated computed tomography (CT) was used to evaluate endograft behaviour. Device interactions were characterised according to gutter volume, gutter surface deviation, and endograft deformation (D-ratio) at end-diastolic and peak-systolic aortic pressure.ResultsUse of BE chimney grafts resulted in three times total gutter volume compared to SE chimney grafts. Gutter volumes were observed to vary dynamically between the end-diastolic and peak-systolic phases of the cardiac cycle, with the most substantial change associated with the BE configuration. Chimney graft deformations were dependent on device type, with SE devices exhibiting up to twice the deformation as BE devices. When adjacent, SE chimney grafts were observed to support each other, and thus tended towards a more consistently circular shape.ConclusionGutter and chimney graft behaviour were dependent on device type, and exhibited both spatial and temporal variability. This study emphasises notable differences between BE and SE double ch-TEVAR configurations which should be considered when evaluating risk of endoleak. The findings reported here also support the use of gated CT to better identify device-related complications with ch-TEVAR, and can be used in the design of next generation devices.</p>","PeriodicalId":23549,"journal":{"name":"Vascular","volume":" ","pages":"779-789"},"PeriodicalIF":0.9,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12311244/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141735127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
VascularPub Date : 2025-08-01Epub Date: 2024-08-07DOI: 10.1177/17085381241273260
Ayfer Aksuoglu
{"title":"Where are hematology nurses in surgery?","authors":"Ayfer Aksuoglu","doi":"10.1177/17085381241273260","DOIUrl":"10.1177/17085381241273260","url":null,"abstract":"","PeriodicalId":23549,"journal":{"name":"Vascular","volume":" ","pages":"978"},"PeriodicalIF":0.9,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141903060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
VascularPub Date : 2025-08-01Epub Date: 2024-08-09DOI: 10.1177/17085381241273141
Renxi Li, Anton Sidawy, Bao-Ngoc Nguyen
{"title":"Preoperative anemia is a risk factor for worse 30-day outcomes in both open and endovascular repair of non-ruptured infrarenal abdominal aortic aneurysm.","authors":"Renxi Li, Anton Sidawy, Bao-Ngoc Nguyen","doi":"10.1177/17085381241273141","DOIUrl":"10.1177/17085381241273141","url":null,"abstract":"<p><p>BackgroundAnemia is a highly prevalent condition potentially linked to chronic inflammation. Preoperative anemia is an independent risk factor across many surgical fields. However, the relationship between anemia and abdominal aortic aneurysm (AAA) repair outcomes remains unclear. This study aimed to examine the effects of preoperative anemia on 30-day outcomes of non-ruptured infrarenal AAA repair.MethodsPatients who underwent open surgical repair (OSR) and endovascular aneurysm repair (EVAR) for infrarenal AAA were identified in National Surgical Quality Improvement Program (NSQIP) targeted databases from 2012 to 2021. Anemia was defined as preoperative hematocrit less than 39% in males and 36% in females. Multivariable logistic regression was used to compare 30-day perioperative outcomes between anemic and non-anemic patients, adjusting for demographics, comorbidities, indications, aneurysm extents, operation time, and surgical approaches.ResultsThere were 408 (22.13%) anemic and 1436 (77.88%) non-anemic patients who underwent OSR for non-ruptured AAA, while 3586 (25.20%) patients with and 10,644 (74.80%) without anemia underwent EVAR. In both OSR and EVAR, anemic patients had higher risks of bleeding requiring transfusion (OSR, aOR = 2.446, <i>p</i> < .01; EVAR, aOR = 3.691, <i>p</i> < .01), discharge not to home (OSR, aOR = 1.385, <i>p</i> = .04; EVAR, aOR = 1.27, <i>p</i> < .01), and 30-day readmission (OSR, aOR = 1.99, <i>p</i> < .01; EVAR, aOR = 1.367, <i>p</i> < .01). Also, anemic patients undergoing OSR had higher pulmonary events (aOR = 2.192, <i>p</i> < .01), sepsis (aOR = 2.352, <i>p</i> < .01), and venous thromboembolism (aOR = 2.913, <i>p</i> = .01), while in EVAR, anemic patients had higher mortality (aOR = 1.646, <i>p</i> = .01), cardiac complications (aOR = 1.39, <i>p</i> = .04), renal dysfunction (aOR = 1.658, <i>p</i> = .02), and unplanned reoperation (aOR = 1.322, <i>p</i> = .01). Moreover, in both OSR and EVAR, anemic patients had longer hospital length of stay (<i>p</i> < .01).ConclusionIn OSR and EVAR, preoperative anemia was independently associated with worse 30-day outcomes. Preoperative anemia could be a useful marker for risk stratification for patients undergoing infrarenal AAA repair.</p>","PeriodicalId":23549,"journal":{"name":"Vascular","volume":" ","pages":"803-813"},"PeriodicalIF":0.9,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141914164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}