Vascular最新文献

{"title":"Inflammation and lower extremity peripheral arterial disease: Imaging complexity or functional severity.","authors":"Mesut Engin, Ahmet Burak Tatlı, Ahmet Kagan As","doi":"10.1177/17085381251339689","DOIUrl":"10.1177/17085381251339689","url":null,"abstract":"","PeriodicalId":23549,"journal":{"name":"Vascular","volume":" ","pages":"505-506"},"PeriodicalIF":0.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144052270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrasound-guided popliteal sciatic nerve block versus traditional analgesia for early perioperative pain relief in severe chronic lower extremity arterial occlusive disease: A retrospective study.","authors":"Jie Zhang, Zeyi Zhao","doi":"10.1177/17085381251339937","DOIUrl":"10.1177/17085381251339937","url":null,"abstract":"<p><p>ObjectiveChronic lower extremity arterial occlusive disease (LEAO) presents significant diagnostic and management challenges, often requiring effective perioperative pain management to enhance patient outcomes. This study evaluated the efficacy of ultrasound-guided popliteal sciatic nerve block (PSNB) compared to traditional analgesia in managing early perioperative pain and improving microcirculation in patients with severe LEAO.MethodsThis retrospective, exploratory study involved 92 patients with Fontaine classification III and IV LEAO, treated from January 2021 to December 2022. Patients were divided into two groups: those receiving traditional analgesia with fentanyl patches and those undergoing PSNB. Clinical outcomes assessed included early perioperative pain intensity using the Visual Analogue Scale (VAS), Toe-Brachial Index (TBI), foot temperature (FT), and feet transcutaneous oxygen pressure (FTpO2). Data on tramadol usage and results from lower limb ultrasound post-analgesia were also collected.ResultsPSNB was associated with significantly lower VAS scores and higher TBI, foot temperature, and transcutaneous oxygen pressure compared to traditional analgesia, indicating enhanced pain management and microcirculation. Furthermore, PSNB patients showed a significantly reduced consumption of tramadol and improved collateral circulation in the lower limbs as evaluated on the fifth day post-analgesia.ConclusionPSNB provides superior pain control and enhances microcirculatory outcomes in the early perioperative period for patients with severe LEAO, presenting a promising alternative to traditional analgesic methods. These findings suggest that PSNB has the potential to improve early perioperative management in LEAO, although further research is needed to confirm these results across broader populations.</p>","PeriodicalId":23549,"journal":{"name":"Vascular","volume":" ","pages":"465-471"},"PeriodicalIF":0.7,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13013643/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144001790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of monocyte-to-high-density lipoprotein cholesterol ratio with peripheral artery disease and long-term mortality.","authors":"Tianbo Wang, Yue Zhang, Chenli Fang, Junbo Xu","doi":"10.1177/17085381251339242","DOIUrl":"10.1177/17085381251339242","url":null,"abstract":"<p><p>BackgroundThis study aims to investigate the association of monocyte-to-high-density lipoprotein cholesterol ratio (MHR) with peripheral artery disease (PAD) and long-term mortality.MethodsData from the National Health and Nutrition Examination Survey (NHANES) from 1999 to 2004 were analyzed, with mortality follow-up tracked via the National Death Index until December 31, 2019. Logistic regression was used to examine the relationship between MHR and PAD, while Cox proportional hazards regression assessed the association of MHR with mortality in individuals with PAD.ResultsA total of 6319 participants were included, among whom 550 were identified as having PAD. In weighted multivariate logistic regression analysis, participants in the third (odds ratio [OR]: 1.031, 95% confidence interval [CI]: 1.009-1.053, <i>p</i> = 0.007) and fourth (OR: 1.034, 95% CI: 1.011-1.057, <i>p</i> = 0.006) quartiles of MHR demonstrated significantly higher risks of PAD compared to those in the first quartile. Among PAD individuals, during a median follow-up period of 136 (71, 197) months, 422 deaths occurred. Higher MHR was associated with an increased risk of long-term mortality in females (hazard ratio [HR]: 1.695, 95% CI: 1.222-2.350, <i>p</i> = 0.002) but not in males (HR: 0.761, 95% CI: 0.554-1.044 <i>p</i> = 0.090).ConclusionsElevated MHR is independently associated with PAD among U.S. population. The association between MHR and long-term prognosis of PAD exhibits gender differences, with a significant relationship observed between elevated MHR and long-term mortality risk in females, but not in males.</p>","PeriodicalId":23549,"journal":{"name":"Vascular","volume":" ","pages":"445-453"},"PeriodicalIF":0.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143984691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Venous stents for post-EVAR graft limb kinking: two case reports.","authors":"Henrique Guedes da Rocha, Carlos Veterano, Paulo Almeida, Pedro Sá Pinto, Carolina Vaz, Rui Machado","doi":"10.1177/17085381251339237","DOIUrl":"10.1177/17085381251339237","url":null,"abstract":"<p><p>ObjectivesTo assess dedicated venous stents' feasibility and early outcomes as a post-EVAR graft limb kinking treatment.MethodsWe report two clinical cases of severe graft limb kinking detected 1 year after EVAR.ResultsBoth patients were successfully treated with dedicated venous stents and experienced no further aortic-related events during follow-up. Graft limb kinking is a common EVAR complication, particularly in anatomically complex cases involving iliac tortuosity. Current literature emphasises the evaluation of graft-related complications but lacks recommendations for preemptive stenting or standardised management.ConclusionsOur findings highlight the potential of venous stents' adaptability to challenging anatomy vessels. Venous stents' flexibility and high radial force may reduce early occlusion rates. Further research is needed to compare the outcomes of dedicated venous stents with bare-metal stents and to optimise prevention and treatment strategies for post-EVAR graft limb kinking.</p>","PeriodicalId":23549,"journal":{"name":"Vascular","volume":" ","pages":"299-302"},"PeriodicalIF":0.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144053474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early outcome of percutaneous mechanical thrombectomy using the AcoStream device in combination with other endovascular therapies for deep vein thrombosis in a lower extremity.","authors":"Zuanbiao Yu, Tiequan Yang, Ming Cai, Songjie Hu, Di Wang, Yafang Shao, Dehai Lang","doi":"10.1177/17085381251347865","DOIUrl":"10.1177/17085381251347865","url":null,"abstract":"<p><p>ObjectiveTo evaluate the efficacy and safety of the AcoStream device (Acotec Scientific, Beijing, China) when used in combination with other endovascular therapies in patients with deep vein thrombosis (DVT) in a lower extremity.MethodsThis single-center retrospective study included 126 consecutive patients who were treated for DVT at our institution between December 2022 and August 2024. Mechanical aspiration of thrombus using the AcoStream device was performed under local anesthesia in all cases. Residual thrombus of >30% after aspiration mechanical thrombectomy was treated by catheter-directed thrombolysis. Percutaneous balloon dilatation and stent implantation were performed in the event of residual iliac vein stenosis of >50%. We analyzed related indices during aspiration mechanical thrombectomy and evaluated the early outcome during follow-up.ResultsTechnical success (>70% resolution of thrombus) was achieved in 110 patients (87.3%). Seventy-six patients (60.3%) also underwent catheter-directed thrombolysis (mean duration 4.47 ± 2.69 days and mean urokinase dose 33.19 ± 9.58 *10,000 IU per day), and 71 (56.3%) also underwent balloon dilatation and stent implantation. The mean decrease in hemoglobin after aspiration mechanical thrombectomy was 15.20 ± 10.21 g/L. There were no major complications. The median follow-up duration was 7.87 ± 3.56 months. The primary patency rate was 92.9% (117/126). Thrombus recurred in five patients (in-stent thrombosis, <i>n</i> = 4; re-thrombosis, <i>n</i> = 1) and was treated successfully by catheter-directed thrombolysis. Post-thrombotic syndrome occurred in 7.1% of patients, including one with a venous ulcer.ConclusionsThe findings of this study indicate that use of the AcoStream device combined with other endovascular therapies is a feasible and effective treatment for DVT with a high technical success rate and satisfactory short-term results.</p>","PeriodicalId":23549,"journal":{"name":"Vascular","volume":" ","pages":"383-389"},"PeriodicalIF":0.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144175098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outcomes of unibody endoprosthesis for treatment of aortic aneurysmal pathology and aortoiliac occlusive disease.","authors":"Benjamin Liu, Caroline Chung, Iman Mohammed, Chase Schlesselman, Todd R Vogel, Steven Cheung, Jonathan Bath","doi":"10.1177/17085381251360045","DOIUrl":"10.1177/17085381251360045","url":null,"abstract":"&lt;p&gt;&lt;p&gt;ObjectiveUnibody Endoprosthesis (UBE) is a newer treatment modality for abdominal aortic pathology (AAP) and has increasingly been utilized for aortoiliac occlusive disease (AIOD). We report outcomes of patients undergoing UBE for AAP and AIOD.MethodsPatients (2016-2021) undergoing UBE were identified retrospectively at an academic institution. AAP included aneurysm/pseudoaneurysm/PAU. Chi-square and Kaplan-Meier analysis were used to evaluate outcomes by group.Results90 patients undergoing UBE were included with 39 patients undergoing AAP (43%) and AIOD treatment in 51 (57%). AAP patients were older (72.9 vs 62.5 years; &lt;i&gt;p&lt;/i&gt; = .01), with a lower prevalence of female patients treated than AIOD (36% vs 57%; &lt;i&gt;p&lt;/i&gt; = .04), diabetes (23% vs 45%; &lt;i&gt;p&lt;/i&gt; = .03) and current smokers (46% vs 69%; &lt;i&gt;p&lt;/i&gt; = .03). There were significant differences in arterial diameters with AAP patients exhibiting larger minimum aortic diameter (19 mm vs 15 mm; &lt;i&gt;p&lt;/i&gt; &lt; .0001), iliac (12.5 mm vs 9.8 mm; &lt;i&gt;p&lt;/i&gt; &lt; .0001), femoral (9 mm vs 6.9 mm; &lt;i&gt;p&lt;/i&gt; &lt; .0001), SFA (6.8 mm vs 5.2 mm; &lt;i&gt;p&lt;/i&gt; &lt; .0001) and profunda femoris (6 mm vs 4.9 mm; &lt;i&gt;p&lt;/i&gt; = .002). Shorter surgery duration was seen with AAP than AIOD patients (135 min vs 194 min; &lt;i&gt;p&lt;/i&gt; = .001). There were six major amputations in the overall cohort with two BKA and four AKA. There were no significant differences in unadjusted 30-day outcomes or mid-term outcomes between groups at a mean follow-up period of 20 months. Reinterventions over the follow-up period occurred in 9 limbs (5%) in the overall cohort with no significant associations between demographic or anatomic variables identified. Subgroup analysis of the whole cohort by sex revealed that female patients exhibited smaller minimum aortic diameter (14.9 mm vs 18.6 mm; &lt;i&gt;p&lt;/i&gt; &lt; .0001), common iliac (9.3 mm vs 12.5 mm; &lt;i&gt;p&lt;/i&gt; &lt; .0001), femoral (6.9 mm vs 8.7; &lt;i&gt;p&lt;/i&gt; &lt; .0001), SFA (5.2 mm vs 6.6 mm; &lt;i&gt;p&lt;/i&gt; &lt; .0001) and profunda femoris (4.9 mm vs 5.9 mm; &lt;i&gt;p&lt;/i&gt; = .0006). Logistic regression analysis revealed an independent association between minimum aortic diameter (OR 1.61; 95% CI 1.0-2.4) and surgery length (OR 1.02; 95% CI 1-1.03) and overall mortality. Kaplan-Meier estimated survival at 36 months was 94% for AIOD and 84% for AAP (&lt;i&gt;p&lt;/i&gt; = .23). At 36 months, primary patency was 78% for AIOD versus 100% for AAP (&lt;i&gt;p&lt;/i&gt; = .002), primary-assisted patency was 94% for AIOD versus 100% for AAP (&lt;i&gt;p&lt;/i&gt; = .12) and secondary patency for AIOD was 82% versus 100% for AAP (&lt;i&gt;p&lt;/i&gt; = .008).ConclusionsUBE can be safely and effectively used for treating aortic aneurysmal pathology as well as aortoiliac occlusive disease in selected patients. Despite the differing pathologies, outcomes are similar with a low reintervention rate and excellent mid-term patency of the intervention. Interestingly, an independent association between mortality and small minimum aortic diameter was seen, further reinforcing AIOD as a marker for overall m","PeriodicalId":23549,"journal":{"name":"Vascular","volume":" ","pages":"330-341"},"PeriodicalIF":0.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144733533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Physician-modified endografts and carotid-subclavian bypass in the treatment of extensive thoracic aortic aneurysm involving the aortic arch.","authors":"Guangmin Yang, Guangyan Wu, Yepeng Zhang, Min Zhou","doi":"10.1177/17085381251342330","DOIUrl":"10.1177/17085381251342330","url":null,"abstract":"<p><p>ObjectivesThoracic aortic aneurysm (TAA) involving the aortic arch poses a significant risk of cerebrovascular accidents and presents technical challenges for repair. This report presents a hybrid approach combining carotid-subclavian bypass (CSbp) and physician-modified endografts (PMEGs) for a patient with extensive aortic arch involvement.MethodA 77-year-old asymptomatic man with a large TAA extending into the aortic arch underwent a hybrid procedure. The intervention included a CSbp and the deployment of a double-fenestrated PMEG, prepared using a Valiant Captivia stent-graft platform, with additional branches to accommodate supra-aortic vessels.ResultsThe patient's intraoperative and postoperative course was uneventful, with no neurological or vascular complications. Follow-up CTA at 1 year showed a patent carotid-subclavian bypass, well-positioned stent grafts, and no evidence of endoleak or graft migration.ConclusionThe combination of carotid-subclavian bypass and PMEGs offers a feasible and effective treatment for complex TAA involving the aortic arch, particularly in high-risk patients unsuitable for open repair or total endovascular approaches.</p>","PeriodicalId":23549,"journal":{"name":"Vascular","volume":" ","pages":"303-306"},"PeriodicalIF":0.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144080012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anesthesia choice for endovascular repair of complex abdominal aortic aneurysm: A propensity-score-matched study from the ACS-NSQIP database from 2012 to 2022.","authors":"Renxi Li, Anton Sidawy, Bao-Ngoc Nguyen","doi":"10.1177/17085381251339225","DOIUrl":"10.1177/17085381251339225","url":null,"abstract":"<p><p>BackgroundWhile general anesthesia has been the dominant anesthesia used in endovascular aneurysm repair (EVAR), locoregional anesthesia is suggested as a viable alternative for eligible patients. However, the majority of previous findings came from infrarenal EVAR while the choice of anesthesia for complex EVAR remains less established. This study aimed to retrospectively compare the 30-day outcomes of patients who underwent non-emergency complex EVAR under locoregional or general anesthesia.MethodsPatients who had EVAR for complex abdominal aortic aneurysm (AAA) were selected from ACS-NSQIP targeted database between 2012 and 2022. Complex AAA included juxtarenal, suprarenal, or pararenal proximal extent, Type IV thoracoabdominal aneurysm, and/or aneurysms treated with Zenith Fenestrated endograft. Exclusion criteria included age under 18 years, ruptured AAA, acute intraoperative conversion to open, and emergency. A 1:2 propensity-score matching was used to balance demographics, baseline characteristics, aneurysm diameter, distant aneurysm extent, and concomitant procedures between the locoregional and general anesthesia groups. Thirty-day outcomes were examined.ResultsThere were 284 (9.63%) and 2664 (90.37%) patients who underwent EVAR for complex AAA under locoregional and general anesthesia, respectively. All patients under locoregional anesthesia were matched to 549 patients under general anesthesia. Patients under locoregional and general anesthesia had comparable risks of mortality and surgical complications. However, patients under locoregional anesthesia had a shorter hospital length of stay (LOS; 2.37 ± 3.25 vs 3.35 ± 4.81 days, <i>p</i> < .01).ConclusionBoth locoregional and general anesthesia are effective options for eligible patients undergoing complex EVAR. However, patients under general anesthesia had a longer hospital LOS by about 1 day, which was likely due to increased case complexity that may necessitate prolonged recovery and closer monitoring for complications. To further optimize anesthesia protocols for these procedures, future prospective studies may be necessary.</p>","PeriodicalId":23549,"journal":{"name":"Vascular","volume":" ","pages":"253-260"},"PeriodicalIF":0.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144053441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Superficial femoral artery disease as a cardiovascular prognostic predictor in aortoiliac revascularization-A cohort study.","authors":"Ana Sofia-Goncalves, Diogo Domingues-Monteiro, Tiago Costa- Pereira, António Pereira-Neves, Hugo Ribeiro, José Vidoedo, Joao Rocha-Neves","doi":"10.1177/17085381251341086","DOIUrl":"10.1177/17085381251341086","url":null,"abstract":"<p><p>IntroductionAortoiliac disease is a severe manifestation of peripheral artery disease (PAD) that reduces blood flow to the lower limbs, leading to significant morbidity and mortality. Patients with AID frequently present lesions in other arterial territories, particularly in the superficial femoral artery (SFA), which may lead to more challenging and higher risk outcomes in patients. This study aims to evaluate the prognostic value for major adverse cardiovascular events (MACE) of SFA disease in patients undergoing aortoiliac revascularization.MethodsThis prospective cohort study included all consecutive patients who underwent elective aortoiliac revascularization between January 2013 and September 2022 at both a central and a district hospital, representing two healthcare facilities within the Portuguese Health System. Only patients with aortoiliac Transatlantic Inter-Society Consensus (TASC) II type D lesions were included, excluding those with aortoiliac aneurysmal disease. Moreover, patients with severe multivessel disease in other arterial areas, apart from the aortoiliac artery and SFA, were excluded. Patient demographics, clinical characteristics, and procedural details were collected. Outcomes were assessed in the first 30 days post-procedure and during long-term follow-up. Statistical analyses included Kaplan-Meier survival curves and multivariate Cox regression.ResultsA total of 133 patients were included, with a mean age of 62.3 ± 9.23 years; 94.0% were male, and a median follow-up of 61 [IQR: 55.0-67.0] months. SFA disease was present in 60.9% of patients and was associated with hypertension (<i>p</i> = .025), coronary artery disease (<i>p</i> = .005), congestive heart failure (<i>p</i> = .020), and age (<i>p</i> = .008). Patients with SFA disease had a lower 30-day ankle-brachial index (ABI) (<i>p</i> < .001), smaller post-surgery ABI variation (<i>p</i> = .003), longer hospital stays (<i>p</i> = .005), and higher rates of major adverse limb event (MALE) (<i>p</i> = .007). Survival analysis demonstrated increased long-term MALE, MACE, and all-cause mortality in patients with SFA disease. Multivariable analysis confirmed SFA disease as a significant predictor of all-cause mortality (HR = 2.046 [1.042-4.443] <i>p</i> = .048) and suggested a trend towards increased risk of MACE (HR = 1.542, [0.866-3.101], <i>p</i> = .075).ConclusionThis study identifies SFA disease as a critical prognostic marker for adverse cardiovascular outcomes in patients undergoing aortoiliac revascularization. Further research with larger sample sizes and longer follow-up periods is warranted to validate these findings and improve patient management strategies.</p>","PeriodicalId":23549,"journal":{"name":"Vascular","volume":" ","pages":"482-490"},"PeriodicalIF":0.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143988336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prioritizing relieving iliac venous compression contributes to treating varicose veins of lower extremities patients with May-Thurner syndrome.","authors":"Meng-Jie Shi, Xi Yuan, Yan Yan, Rui-Peng Zhang, Fei Liu, Shi-Cai He, Hui Wang","doi":"10.1177/17085381251360068","DOIUrl":"10.1177/17085381251360068","url":null,"abstract":"<p><p>ObjectiveWe suspect that the May-Thurner syndrome (MTS) is the main etiology of secondary varicose veins of the lower extremities (VVLE). However, there is no definitive agreement on the priority and necessity of relieving iliac vein compression when treating patients with VVLE and MTS.MethodIn this study, according to the results of anterograde venography of lower extremity, 99 patients were divided into two groups, namely, simple VVLE (<i>n</i> = 66) and VVLE-MTS groups (<i>n</i> = 33). The patients in the former group only received sclerotherapy, while the patients in later group received the combination treatments of intravascular balloon dilatation, stent placement of iliac vein, and sclerotherapy. After surgery, we applied VVCS score, postoperative recanalization rate, and improvement in clinical symptom to assess therapeutic effects.ResultsVCSS score: At 1 week, 1 month, 3 months, and 6 months after operation, there were significant differences between group A and group B (<i>p</i> < 0.01), the difference of VCSS: compared with preoperation, there was statistical difference between group A and group B at 1 week after operation (<i>p</i> < 0.01), there was no statistical difference 6 months after operation (<i>p</i> = 0.052); Postoperative recanalization: cumulative trunk recanalization events 6 months after surgery There was no statistical difference between (<i>p</i> = 0.192) and branch recanalization events (<i>p</i> = 0.207). When the two events were combined to increase the positive rate, no statistical difference was found. However, after stratifying patients, mild (CEAP2-3) and moderate (CEAP4) patients were obtained. There was no statistical difference in the incidence of recanalization events between the two groups, but there was a statistical difference between severe (CEAP5-6) groups (<i>p</i> = 0.025).ConclusionIt was great of importance and necessity of solving iliac vein compression prior to treating VVLE when handling patients with VVLE and MTS, especially for the cases with high CEAP score.</p>","PeriodicalId":23549,"journal":{"name":"Vascular","volume":" ","pages":"396-404"},"PeriodicalIF":0.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144601719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}