韩国全国范围内的 EVAR 取出结果分析:综合数据集研究。

IF 0.9 4区 医学 Q4 PERIPHERAL VASCULAR DISEASE
Vascular Pub Date : 2025-08-01 Epub Date: 2024-07-22 DOI:10.1177/17085381241265159
Hyo Kee Kim, Pyoung Jae Park, Jee Hyun Park, Young Ju Oh, Cheol Woong Jung, Heungman Jun
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引用次数: 0

摘要

目的:血管内主动脉瘤修补术(EVAR)是腹主动脉瘤的主要治疗方法,占介入治疗的 70%-80% 。尽管最初的治疗效果不错,但长期研究显示死亡率有所上升。本研究利用全国范围的数据,评估了韩国EVAR、开放式主动脉修补术(OAR)和EVAR切除术(EE)的结果,同时探讨了晚期开放式转换的特点,包括EE发生率的上升:该研究采用国民健康保险服务数据库,涵盖近 5000 万韩国人的健康相关数据,时间跨度为 2002 年至 2020 年。根据手术代码将诊断为 AAA(I71.3 或 I71.4)的患者分为 OAR 组、EVAR 组和 EE 组。统计分析包括 t 检验、费雪精确检验、Cox 比例危险模型和多变量 Cox 回归,评估了 EE 组的基线特征、死亡风险和因素:分析包括 26,195 例患者,其中 EVAR 组占 66.19%,OAR 组占 31.87%,EE 组占 1.94%。从2002年到2018年,EVAR病例稳步增加。存活率方面,EVAR 更受青睐,其次是 OAR 和 EE。EE的30天存活率低于EVAR。EE的多变量分析显示,30天存活率没有风险因素,但年龄、慢性肾脏疾病、Charlson综合指数评分高以及EVAR后不足6个月是总死亡率的风险因素:结论:随着EVAR应用的增加,EE呈上升趋势,这在韩国的数据集中尤为明显,这凸显了较差的治疗效果。结论:随着EVAR应用的增加,EE呈上升趋势,这在韩国的数据集中尤为明显,突显了较差的治疗效果。这凸显了对战略性初始治疗决策和及时干预的迫切需要,以提高总体治疗效果并降低不利的EE发生率。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Nationwide analysis of EVAR explantation outcomes in Korea: A comprehensive dataset study.

ObjectiveEndovascular aortic aneurysm repair (EVAR) is the primary treatment for abdominal aortic aneurysms, constituting 70%-80% of interventions. Despite initial benefits, long-term studies show increased mortality. Using nationwide data, this study assesses outcomes of EVAR, open aortic repair (OAR), and EVAR explantation (EE) in Korea, while exploring characteristics of late open conversion, including the rising EE incidence.MethodsEmploying the National Health Insurance Service database, covering health-related data for nearly 50 million Koreans, the study spanned from 2002 to 2020. Patients with AAA diagnoses (I71.3 or I71.4) were categorized into OAR, EVAR, and EE groups based on procedural codes. Statistical analyses, including t-tests, Fisher's exact tests, Cox proportional hazard models, and multivariate Cox regression, assessed baseline characteristics, mortality risks, and factors within the EE group.ResultsThe analysis encompassed 26,195 patients, with 66.19% in the EVAR group, 31.87% in the OAR group, and 1.94% in the EE group. EVAR cases steadily increased from 2002 to 2018. Survival rates favored EVAR, followed by OAR and EE. 30-day survival was lower in EE than EVAR. Multivariate analysis for EE revealed no risk factors for 30-days survival but identified age, chronic kidney disease, high Charlson Comorbidity Index scores, and less than 6 months since EVAR as risk factors for overall mortality.ConclusionRising EE trends with increased EVAR adoption, particularly evident in the Korean dataset, underscore inferior outcomes. This highlights the critical need for strategic initial treatment decisions and timely interventions to enhance overall results and mitigate the unfavorable EE incidence.

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来源期刊
Vascular
Vascular 医学-外周血管病
CiteScore
2.30
自引率
9.10%
发文量
196
审稿时长
6-12 weeks
期刊介绍: Vascular provides readers with new and unusual up-to-date articles and case reports focusing on vascular and endovascular topics. It is a highly international forum for the discussion and debate of all aspects of this distinct surgical specialty. It also features opinion pieces, literature reviews and controversial issues presented from various points of view.
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