{"title":"Gating of false alarms in myocardial ischemia monitoring using ST segment deviation trend estimator","authors":"Mohamed Abdelazez, A. Chan, Homer Yang","doi":"10.1109/MeMeA.2017.7985898","DOIUrl":"https://doi.org/10.1109/MeMeA.2017.7985898","url":null,"abstract":"A false alarm gating system for myocardial ischemia monitoring is proposed to mitigate false alarms resulting from inaccurate estimates of the ST deviation in the electrocardiogram (ECG). The proposed system employs multiple estimates of the ST segment deviation and correlates the trends between these estimates; low correlation can be indicative of an inaccurate estimate. Three correlation methods were considered: 1) Pearson correlation coefficient, 2) Kendall rank correlation, and 3) Spearman rank correlation. The proposed system was tested using 16 ECG signals from the Long-Term ST Database available on Physionet. The baseline performance of the commercial bedside monitor was 78 true alarms and 66 false alarms with precision and recall of 0.54 and 0.79, respectively. Using Spearman rank correlation, the proposed system balanced the gating of false alarms while minimizing the loss of true alarms. The system's true and false alarm rates were 71 and 30, respectively, while attaining precision and recall of 0.70 and 0.72, respectively.","PeriodicalId":235051,"journal":{"name":"2017 IEEE International Symposium on Medical Measurements and Applications (MeMeA)","volume":"52 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124349975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Preejith Sreeletha Premkumar, A. Jeelani, P. Maniyar, J. Joseph, M. Sivaprakasam
{"title":"Accelerometer based system for continuous respiratory rate monitoring","authors":"Preejith Sreeletha Premkumar, A. Jeelani, P. Maniyar, J. Joseph, M. Sivaprakasam","doi":"10.1109/MeMeA.2017.7985870","DOIUrl":"https://doi.org/10.1109/MeMeA.2017.7985870","url":null,"abstract":"Recent advances in sensor technologies, wireless connectivity, cloud storage and availability of compact hardware allow for designing of cost effective physiological monitoring devices. There is a growing demand for wearable technologies with continuous and minimally intrusive physiological parameter monitoring capabilities. Continuous respiratory rate monitoring using a three-axis accelerometer from the sternum or abdomen is highly challenging due to motion corruption and presents a potential area of research. A system design for continuous and long term respiratory rate monitoring, in a wearable form factor with capability of remote monitoring is presented in this paper. The device runs on a low power ARM Cortex M0 microcontroller and uses inbuilt BLE (Bluetooth Low energy) module for wireless connectivity. A respiratory rate computation algorithm using motion artifact rejection is implemented on the device for reliable performance. Respiratory rate computation by the device was validated in a controlled setting, against gas pressure sensor on 20 subjects. The system architecture, device design, algorithm implementation and experimental validation of the proposed modality are presented.","PeriodicalId":235051,"journal":{"name":"2017 IEEE International Symposium on Medical Measurements and Applications (MeMeA)","volume":"58 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129259087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Lay-Ekuakille, G. Griffo, R. Morello, C. D. Capua, F. Spano
{"title":"Sensing system for cystic fibrosis: Modeling the detection and characterization of sweat","authors":"A. Lay-Ekuakille, G. Griffo, R. Morello, C. D. Capua, F. Spano","doi":"10.1109/MeMeA.2017.7985890","DOIUrl":"https://doi.org/10.1109/MeMeA.2017.7985890","url":null,"abstract":"Sweat assumes an important duty for the diagnostic of diverse pathologies since it is mostly a synthesis of human being physiological functions and its content is a dedicated indicator. It is an indicator of vegetative innervation, and disturbances of nervous systems. Sodium chloride, for instance, is one of the indicators of cystic fibrosis. The paper illustrates the modeling of a sensing system and its related architectures to detect the sodium chloride for the diagnosis of cystic fibrosis. The system is partly in micro and nanotechnology. The paper presents first a dedicated hardware for conditioning and processing signal deriving from a sensor for sweat characterization. The experimental board has been realized using common components but it can be reduced to micro and nanotechnology configuration. This realization, even carried out with a traditional board, demonstrates two positive results: nonlinearity of sodium concentration and reaction time. However, noise contributes to lower the experimental uncertainty. To improve the features, especially in terms of lowering uncertainty and further reaction time (response time), a design of a dedicated sensor for detecting sweat is performed. It is an ISFET (ion-sensitive field effect transistor) using MEMS technology.","PeriodicalId":235051,"journal":{"name":"2017 IEEE International Symposium on Medical Measurements and Applications (MeMeA)","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116551910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L. Scalise, G. Cosoli, L. Casacanditella, S. Casaccia, J. Rohrbaugh
{"title":"The measurement of blood pressure without contact: An LDV-based technique","authors":"L. Scalise, G. Cosoli, L. Casacanditella, S. Casaccia, J. Rohrbaugh","doi":"10.1109/MeMeA.2017.7985883","DOIUrl":"https://doi.org/10.1109/MeMeA.2017.7985883","url":null,"abstract":"This work is aiming to demonstrate the possibility to assess arterial blood pressure without the need to put any element in physical contact with the subject (except for the signal calibration). The authors have developed a measurement technique for the non contact measurement of blood pressure (BP) as manifest in the carotid artery, based on the use of a laser Doppler vibrometer (LDV). The LDV produces a signal that can be related to the continuous pressure pulse waveform. As such, the signal supports the calculation of some physiologically important time intervals. In this paper, we provide a comparison with the pressure waveform recorded using conventional applanation tonometry: the waveform has an analogous shape and, overall, provides the same characteristics in the time axis. More in details, results show that the systolic blood pressure have a mean deviation of 8% with respect to the reference value (obtained from tonometric data). Fundamental aspects to be considered are the precise laser pointing perpendicularly to the measurement site (to optimize the signal-to-noise ratio), the measurement conditions (e.g. the subject has to remain as still as possible) and also the reflective properties of the subject's skin, which can be improved by applying a proper reflective lotion or tape. The major factors contributing to uncertainty of the LDV measures have been evaluated, in order to identify ways to enhance performance. The current uncertainty value of 15% is not negligible, but does not greatly exceed that of the standard BP measuring devices.","PeriodicalId":235051,"journal":{"name":"2017 IEEE International Symposium on Medical Measurements and Applications (MeMeA)","volume":"490 ","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133286901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jennifer Howcroft, Bruce Wallace, R. Goubran, S. Marshall, M. Porter, F. Knoefel
{"title":"Variation in acceleration driving patterns as a measure of older adult health status","authors":"Jennifer Howcroft, Bruce Wallace, R. Goubran, S. Marshall, M. Porter, F. Knoefel","doi":"10.1109/MeMeA.2017.7985892","DOIUrl":"https://doi.org/10.1109/MeMeA.2017.7985892","url":null,"abstract":"The evaluation of older adult in-car driving data and identification of appropriate driving measures could lead to a better understanding of unsafe driving behaviors and associations with older adult health status. In this paper, the coefficient of variation was examined as a measure for identifying differences related to acceleration driving event variability between 12 physically, cognitively, and general health stable older adult drivers and 16 older adult drivers with declining physical, cognitive, or general health status over a one year period. Declining older adult drivers had significantly lower acceleration coefficient of variation than stable drivers for acceleration event subsets with final velocities between 60 and 100 km/hr, changes in velocities between 15 and 30 km/hr and between 60 and 75 km/hr, and changes in heading between 70 and 180 degrees, which may indicate a reduced adaptation of acceleration driving patterns. Further investigation of acceleration coefficient of variation is warranted to determine whether the decreased acceleration variability in declining drivers is due to physical, cognitive, or general health declines, and to determine the accuracy of this measure at identifying older adults with declining health and those with unsafe driving.","PeriodicalId":235051,"journal":{"name":"2017 IEEE International Symposium on Medical Measurements and Applications (MeMeA)","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133910715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Powering wearable sensors with a low-power CMOS piezoelectric energy harvesting circuit","authors":"Taeho Oh, S. Islam, G. To, M. Mahfouz","doi":"10.1109/MeMeA.2017.7985894","DOIUrl":"https://doi.org/10.1109/MeMeA.2017.7985894","url":null,"abstract":"Piezoelectric vibration based energy harvesters have been widely researched as powering modules for various types of sensor systems due to their ease of integration and high energy density. A number of piezoelectric transducer based topologies have been reported in literature. In this paper a piezoelectric transducer in parallel with a switch along with a low-power CMOS full-bridge rectifier is presented as a solution for efficient energy harvesting system for potential application in medical electronics. It consists of two NMOS and two PMOS devices comprising a full-bridge rectifier coupled with a PMOS device driven by a comparator based switch control circuit. With a load of 45KΩ, the output rectifier and the input piezoelectric transducer voltages are 694mV and 703mV, respectably, while the VOUT versus VIN conversion ratio is 98.7% with a power efficiency of 46%. The proposed energy harvesting circuit has been designed using a 0.13µm standard CMOS process.","PeriodicalId":235051,"journal":{"name":"2017 IEEE International Symposium on Medical Measurements and Applications (MeMeA)","volume":"284 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121329211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Janca, P. Jezdik, A. Jahodova, M. Kudr, V. Komárek, M. Tichy, P. Krsek
{"title":"Intraoperative thermography in safety control of the electrical stimulation mapping","authors":"R. Janca, P. Jezdik, A. Jahodova, M. Kudr, V. Komárek, M. Tichy, P. Krsek","doi":"10.1109/MeMeA.2017.7985872","DOIUrl":"https://doi.org/10.1109/MeMeA.2017.7985872","url":null,"abstract":"The cortical Electric Stimulation Mapping (ESM) procedure is used as a standard approach to localize and continuously monitor function of the eloquent cortex and corticospinal tract during neurosurgical intervention. However, eliciting motor responses using standard ESM paradigm is frequently difficult to young children. We have thus developed and tested a novel EMS protocol, which uses intense, high frequency and short stimulation pulses. However, the intense stimulation peak-peak current (up to 100 mA) possess the potential risk of tissue damage.","PeriodicalId":235051,"journal":{"name":"2017 IEEE International Symposium on Medical Measurements and Applications (MeMeA)","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125011933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A monolithic low-power highly linear pH measurement circuit with wide input detection range and easy calibration","authors":"S. Yuan, Hanfeng Wang, S. Islam","doi":"10.1109/MeMeA.2017.7985900","DOIUrl":"https://doi.org/10.1109/MeMeA.2017.7985900","url":null,"abstract":"In this paper, a novel topology for a monolithic low-power, highly miniaturized electrochemical pH sensor readout circuit with wide measurement range of pH values is presented. The readout circuit converts the output voltage of a pH sensor, which corresponds to the pH value of a solution under measurement, to a square-wave signal with its frequency being proportional to the pH sensor output voltage. A simple calibration method is employed in the design which makes the output frequency stay constant over process, supply voltage and temperature variations. The prototype system is designed and fabricated using a standard 0.13-µm CMOS process and the measurement results show that the sensor has good linearity to cover the entire pH value range from 0–14. The proposed sensor consumes 12.8 µW of power with 1.25 V supply voltage for a typical pH value of 7 while occupying a die area of 0.017 mm2. These features make the readout circuit with the pH sensor a promising solution for continuous monitoring of pH values in a wide range of applications such as real-time monitoring of physiological parameters and environmental monitoring.","PeriodicalId":235051,"journal":{"name":"2017 IEEE International Symposium on Medical Measurements and Applications (MeMeA)","volume":"2016 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127367043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Belle, H. Enright, E. Mukerjee, D. Soscia, J. Osburn, E. Kuhn, K. Kulp, E. Wheeler, Vanessa M. Tolosa
{"title":"Measurement of glutamate in dorsal root ganglion cell culture with integrated electrochemical biosensors","authors":"A. Belle, H. Enright, E. Mukerjee, D. Soscia, J. Osburn, E. Kuhn, K. Kulp, E. Wheeler, Vanessa M. Tolosa","doi":"10.1109/MeMeA.2017.7985919","DOIUrl":"https://doi.org/10.1109/MeMeA.2017.7985919","url":null,"abstract":"Here we describe the fabrication, testing, and improvement of glutamate sensors in direct contact with dorsal root ganglion cells for short-term tissue culture experiments. To establish the feasibility and utility of placing enzymatic glutamate sensors directly under cells in culture, we address the necessity of increasing sensor sensitivity, increasing sensor lifetime, minimizing disruption of cells in culture, and of the spatial resolution seen with sensors directly under cells based on these results.","PeriodicalId":235051,"journal":{"name":"2017 IEEE International Symposium on Medical Measurements and Applications (MeMeA)","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116447580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
B. Karaboce, Emel Çetin, H. Durmuş, Mithat Ozdingis, H. Korkmaz, Julide Altun, Serhan Argun
{"title":"Experimental investigations of viscous heating effect of thermocouples under focused ultrasound applications","authors":"B. Karaboce, Emel Çetin, H. Durmuş, Mithat Ozdingis, H. Korkmaz, Julide Altun, Serhan Argun","doi":"10.1109/MeMeA.2017.7985855","DOIUrl":"https://doi.org/10.1109/MeMeA.2017.7985855","url":null,"abstract":"Realization of temperature characterization on focused ultrasound treatment devices by using tissue-mimicking phantom systems (Tissue-Mimicking Material, TMM) is indispensible in pre-clinical studies. In this survey, in order to examine the viscous heating effect of thermocouples, temperature rise due to excitation of a HIFU transducer has been measured by using two different types of T-type thermocouples embedded inside the TMM. In order to obtain the temperature values from the thermocouples more effectively, a PC-based multi-channel data acquisition and monitoring interface were developed by using LabVIEW graphical development platform. Measurements were carried out inside a TMM which has characteristics like human liver tissue. Temperature rise has been characterized for the different input ultrasonic powers (25 W, 38 W and 50 W) and frequencies (1,1 MHz and 3.3 MHz) and the time intervals applied (1 s, 2 s and 3 s). The temperature values obtained from two different types of T-type thermocouple were compared to each other and discrepancies between these two different thermocouple measurements were shown with the study.","PeriodicalId":235051,"journal":{"name":"2017 IEEE International Symposium on Medical Measurements and Applications (MeMeA)","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115325512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}