Value in health regional issues最新文献

{"title":"Main Predictors of Decreasing in Quality of Life in Patients With Post-COVID-19: A Cross-Sectional Study","authors":"Jonnathan O. Cázares-Lara MD ,&nbsp;Alberto Ordinola-Navarro MD ,&nbsp;Zully Carmona-Aguilera MD ,&nbsp;Gustavo M. Benitez-Altamirano MD ,&nbsp;Luis D. Beltran-Ontiveros MD ,&nbsp;Juan P. Ramirez-Hinojosa MD ,&nbsp;Cesar Lopez-Vejar MD ,&nbsp;Bruno A. Lopez-Luis MD","doi":"10.1016/j.vhri.2024.101039","DOIUrl":"10.1016/j.vhri.2024.101039","url":null,"abstract":"<div><h3>Objective</h3><p>We aimed to assess physical and psychosomatic manifestations of patients with long COVID and their association with a decreased patient’s quality of life (QOL) or different times elapsed since the COVID-19 diagnosis.</p></div><div><h3>Methods</h3><p>This is a cross-sectional study. We retrospectively collected the clinical characteristics of adult patients who had tested positive for SARS-CoV-2 and had symptoms at least as early as 4 weeks after COVID-19 in México City between April 2020 and February 2021. A total of 179 were included. They answered questions to define chronic symptoms. The Sniffin’ Sticks Screening 12 test olfactory evaluation was performed. The diminish of QOL was defined by ≥10 points in the EuroQol visual analog scale between pre- and post-COVID-19, and each dimension of EQ-5D-5L test was evaluated. Chi-square test, Fisher’s exact test, Student <em>t</em> test, Wilcoxon rank-sum, and signed-rank test were used as required. A backward stepwise logistic regression analysis determined the factors associated with a decrease in QOL. All analyses were performed using R software version 3.6.3 (R Foundation).</p></div><div><h3>Results</h3><p>In the multivariable analysis, post-COVID-19 pain/discomfort (adjusted odds ratio [aOR] 2.5 [1.66-9.68]; <em>P</em> = .01), anxiety/depression (aOR 13 [1.44-17.23]; <em>P</em> = .03), and persistence of ≥3 symptoms (aOR 2.6 [0.96-7.47]; <em>P</em> = .05) remained statistically significant associated with decreased QOL.</p></div><div><h3>Conclusions</h3><p>Patients with long COVID-19 have decreased QOL mainly associated with pain/discomfort, anxiety/depression, and ≥3 persistent symptoms. Our findings enhanced the notion of a strong psychosomatic factors involved with long COVID-19. Therefore, these patients might benefit from neuropsychological rehabilitation, although the effect of such interventions should be evaluated.</p></div>","PeriodicalId":23497,"journal":{"name":"Value in health regional issues","volume":"45 ","pages":"Article 101039"},"PeriodicalIF":1.4,"publicationDate":"2024-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2212109924000724/pdfft?md5=9b46d1178d49c8b47b72cfafda364c75&pid=1-s2.0-S2212109924000724-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142162434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An EQ-5D-5L Value Set for Ghana Using an Adapted EuroQol Valuation Technology Protocol","authors":"Rebecca Addo PhD ,&nbsp;Brendan Mulhern PhD ,&nbsp;Richard Norman PhD ,&nbsp;Richmond Owusu PhD ,&nbsp;Rosalie Viney PhD ,&nbsp;Justice Nonvignon PhD","doi":"10.1016/j.vhri.2024.101045","DOIUrl":"10.1016/j.vhri.2024.101045","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Objectives&lt;/h3&gt;&lt;p&gt;Ghana’s economic evaluation reference case recommends quality-adjusted life-years as an outcome measure for the conduct of cost-utility analysis. There is no Ghanaian value set available to be used in estimating quality-adjusted life-years. This study aimed to develop a value set for Ghana using the EQ-5D-5L instrument.&lt;/p&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Methods&lt;/h3&gt;&lt;p&gt;Face-to-face preference data were collected from 300 adults across 3 regions of Ghana using the adapted version of the EuroQol valuation technology (EQ-VT) standardized valuation protocol; with composite time-trade-off (cTTO) and discrete-choice experiments (DCEs) elicitation techniques. The cTTO and DCE data were modeled individually or together to provide complementary results on respondents’ utility preferences. Models explored were generalized least squares, Tobit, heteroskedastic, logit, and hybrid. The best-fitting model for the value set was selected based on its logical consistency, accounting for left-censored and heteroscedasticity data, and the statistical significance of parameters.&lt;/p&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;p&gt;The 300 interviews provided 4500 cTTO responses and 4200 DCE responses. The preferred model chosen for the Ghana value set was the Hybrid Tobit random effect heteroscedastic-constrained model. The predicted value for the worst attainable health state (55555) was −0.493 and the best health state (11112) was 0.969. The largest decrement was registered for level 5 mobility (0.369) followed by pain/discomfort (0.312), self-care (0.273), anxiety/depression (0.271), and usual activities (0.268).&lt;/p&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Conclusions&lt;/h3&gt;&lt;p&gt;This is the first Ghanaian EQ-5D-5L value set based on social preference derived from a nationally representative sample. The value set will play a key role in the use of economic evaluation studies to inform priority setting in Ghana where different health technologies can be compared.&lt;/p&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Introducción&lt;/h3&gt;&lt;p&gt;El caso de referencia de la evaluación económica de Ghana recomienda los años de vida ajustados por calidad (AVAC) como medida de resultado para la realización de análisis de costo-utilidad. No existe ningún conjunto de valores ghaneses disponible para utilizar en la estimación de los AVAC. Este estudio tuvo como objetivo desarrollar un conjunto de valores para Ghana utilizando el instrumento EQ-5D-5L.&lt;/p&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Método&lt;/h3&gt;&lt;p&gt;Se recopilaron datos de preferencia cara a cara de 300 adultos en tres regiones de Ghana utilizando la versión adaptada del protocolo de valoración estandarizado de la tecnología de valoración EuroQol (EQ-VT); con técnicas de obtención de experimentos de elección discreta (DCE) y compensación de tiempo compuesto (cTTO). Los datos de cTTO y DCE se modelaron individualmente o en conjunto para proporcionar resultados complementarios sobre las preferencias de servicios públicos de los encuestados. Los modelos explorados fueron mínimos cuadrados generalizados, Tobit, heterocedástico,","PeriodicalId":23497,"journal":{"name":"Value in health regional issues","volume":"45 ","pages":"Article 101045"},"PeriodicalIF":1.4,"publicationDate":"2024-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2212109924000785/pdfft?md5=37c377aa82fe62b47be3780d62f60f13&pid=1-s2.0-S2212109924000785-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142136872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patient Experience of Herpes Zoster Disease in Argentina: Validation of a Health-Related Quality of Life Conceptual Model","authors":"Maria Belizan MSc ,&nbsp;Federico Augustovski MD, PhD ,&nbsp;Ariel Bardach MD, PhD ,&nbsp;Thatiana Pinto PhD ,&nbsp;Agustina Villarejo MSc ,&nbsp;Elena Lazo MD, MSc ,&nbsp;Maria V. Cordo MD ,&nbsp;Desirée A.M. van Oorschot MSc","doi":"10.1016/j.vhri.2024.101044","DOIUrl":"10.1016/j.vhri.2024.101044","url":null,"abstract":"<div><h3>Objectives</h3><p>Herpes zoster (HZ) substantially affects patients’ health-related quality of life (HRQoL), both in the acute phase and also in those developing postherpetic neuralgia (PHN). Building upon a previous qualitative concept elicitation study in Canada, we adopted a similar approach to further understand the patient experience of HZ/PHN in Argentina and impact on quality of life and qualitatively validate the previously published conceptual model for Argentina.</p></div><div><h3>Methods</h3><p>(1) Comprehensive literature review of HZ impact on HRQoL in Latin America. (2) Qualitative concept elicitation interviews with participants aged ≥50 years with acute HZ or PHN. Verbatim interview transcripts underwent thematic and content analysis related to symptoms and impacts.</p></div><div><h3>Results</h3><p>Studies from the literature (n = 6) identified 5 dimensions of HZ impact on HRQoL: pain management, disease management, family life, work, and emotional impact. A total of 10 participants were interviewed (5 acute HZ and 5 with PHN) with a mean age of 68.5 years (range 50-77 years) and 60% female. All participants reported rash and pain (some reporting a migratory element), fatigue (7 of 10), and itchiness (4 of 10). HRQoL domains most commonly affected were activities of daily living (9 of 10), emotional functioning (8 of 10), physical functioning (8 of 10), and sleep (7 of 10). Emergent themes on disease management included the need for greater public disease awareness/education, participants with PHN seeking alternative/traditional medical therapies.</p></div><div><h3>Conclusions</h3><p>This study qualitatively validates the previously reported HRQoL conceptual framework. HZ symptoms, especially acute and chronic pain, substantially impair various aspects of HRQoL, prompting some participants to seek out alternative medical treatments.</p></div>","PeriodicalId":23497,"journal":{"name":"Value in health regional issues","volume":"44 ","pages":"Article 101044"},"PeriodicalIF":1.4,"publicationDate":"2024-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2212109924000773/pdfft?md5=7c713428d4d8079151c5c2bdf37adad4&pid=1-s2.0-S2212109924000773-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142128708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Health Services Costs of Clinical Heart Failure With Reduced Ejection Fraction in Singapore","authors":"Sameera Senanayake PhD ,&nbsp;Sanjeewa Kularatna PhD ,&nbsp;Audry Shan Yin Lee MBBChir ,&nbsp;Annie Lee PhD ,&nbsp;Yee How Lau BSc ,&nbsp;Derek J. Hausenloy PhD ,&nbsp;Khung-Keong Yeo MBBS ,&nbsp;Mark Yan-Yee Chan PhD ,&nbsp;Raymond Ching Chiew Wong MBBS ,&nbsp;Seet Yoong Loh MBBS ,&nbsp;Kheng Leng David Sim MBBS ,&nbsp;Chow Weien MMed ,&nbsp;Nicholas Graves PhD","doi":"10.1016/j.vhri.2024.101037","DOIUrl":"10.1016/j.vhri.2024.101037","url":null,"abstract":"<div><h3>Objectives</h3><p>This study aimed to estimate the annual healthcare burden of heart failure (HF) with reduced ejection fraction (&lt;40%) in Singapore.</p></div><div><h3>Methods</h3><p>Retrospective longitudinal descriptive cohort study was conducted using a linked national administrative data set (Singapore Cardiovascular Longitudinal Outcomes Database). In Singapore, during 2011, there were a total of 3267 HF-related hospital admissions. Among these, 1631 patients (49.9%), who had an ejection fraction of less than 40%, were followed up for 9 years. The primary outcomes were annual healthcare costs related to hospital admissions and outpatient visits.</p></div><div><h3>Results</h3><p>There was a consistent decline in HF-related hospital admissions over the years, and the average per-hospital admission cost and average cost per day for HF varied over the 9 years. The average all-cause per-patient admission cost remained stable annually, ranging between S$16 000 and S$18 800. In the final year of life, there was a significant increase in both all-cause and HF-related hospital admission costs (by 24% and 54% from the previous year, respectively), and this rise in costs reflected increased frequency of admissions and longer hospital stays. There was an upward trend in the cost of outpatient visits as the patients neared death.</p></div><div><h3>Conclusions</h3><p>Hospital-based HF care imposes a significant financial impact on Singapore’s healthcare system. This suggests a need for cost-efficient management strategies to reduce the reliance on hospital-based treatment, thus mitigating economic pressures on the healthcare system.</p></div>","PeriodicalId":23497,"journal":{"name":"Value in health regional issues","volume":"45 ","pages":"Article 101037"},"PeriodicalIF":1.4,"publicationDate":"2024-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2212109924000700/pdfft?md5=b1185b2623e5889927950369567b36da&pid=1-s2.0-S2212109924000700-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142122059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Economic Burden of Sickle Cell Disease in Saudi Arabia","authors":"Emad Shdaifat PhD ,&nbsp;Firas Abu-Sneineh MSN ,&nbsp;Nagla Alsaleh PhD ,&nbsp;Abdallah Ibrahim MSN","doi":"10.1016/j.vhri.2024.101038","DOIUrl":"10.1016/j.vhri.2024.101038","url":null,"abstract":"<div><h3>Objective</h3><p>This study aimed to determine the direct and indirect costs of sickle cell disease (SCD) in Saudi Arabia.</p></div><div><h3>Methods</h3><p>Data were collected from 217 participants aged ≥18 years in the eastern region of Saudi Arabia, using a prevalence-based cost-of-illness approach. The Institute for Medical Technology Assessment Medical Consumption Questionnaire and Institute for Medical Technology Assessment Productivity Cost Questionnaire were used to assess costs. A multistage process was used, encompassing patient data collection over 3 months, cost calculation from clinic visits and drug prices, and extrapolation for annual estimates.</p></div><div><h3>Results</h3><p>The study revealed substantial societal costs of SCD, with an average per-patient cost of SAR181 899 (US$48 506), covering healthcare and productivity losses. Healthcare costs, including hospitalization, informal care, and medication, averaged SAR80 306 (US$21 415). In addition, productivity costs, including unpaid work and presenteeism, averaged SAR101 594 (US$27 092). Obtaining higher levels of education, such as a diploma and BSc degree or higher, has been found to significantly decrease the costs associated with SCD (<em>P</em> = .016, <em>P</em> = .001). Furthermore, when comparing different employment statuses, students (B = −0.301, <em>P</em> = .058) were found to have marginally lower SCD costs, suggesting that their expenses were lower than those of individuals in other employment categories. The predictive model used in this study explained 11.2% of the variation in costs.</p></div><div><h3>Conclusion</h3><p>Our study highlights a significant economic burden of SCD in Saudi Arabia and highlights the need for targeted strategies to alleviate financial challenges and improve patient well-being.</p></div>","PeriodicalId":23497,"journal":{"name":"Value in health regional issues","volume":"45 ","pages":"Article 101038"},"PeriodicalIF":1.4,"publicationDate":"2024-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2212109924000712/pdfft?md5=74332115991fbbd530bf777fa149d6c4&pid=1-s2.0-S2212109924000712-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142096254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patient and Caregiver Preferences for Hemophilia A Treatment in Taiwan: A Discrete Choice Experiment","authors":"Shyh-Shin Chiou MD, PhD ,&nbsp;Te-Fu Weng MD ,&nbsp;Jiaan-Der Wang MD, PhD","doi":"10.1016/j.vhri.2024.101035","DOIUrl":"10.1016/j.vhri.2024.101035","url":null,"abstract":"<div><h3>Objectives</h3><p>This study evaluated the treatment preferences among patients and caregivers for moderate or severe hemophilia A in Taiwan.</p></div><div><h3>Methods</h3><p>This cross-sectional study used a discrete choice experiment approach to assess treatment preferences among patients with hemophilia A and their caregivers. Respondents chose between 2 hypothetical treatments defined by 7 attributes including no bleeding episode, treated events of joint bleeding, long-term safety, type of treatment and risk of thromboembolic events, administration frequency, consumption route, and monitoring dosing options. Preference weights and relative importance (RI) of attributes were estimated using a hierarchical Bayesian logistic regression model.</p></div><div><h3>Results</h3><p>A total of 51 eligible respondents completed the discrete choice experiment (patients, 76.5%; caregivers, 23.5%). Most patients (70.6%) had severe hemophilia and 43.1% received prophylactic treatment for &gt;10 years. Respondents valued “type of treatment and risk of thromboembolic events” as the most important factor (RI 26.2%; 95% CI 20.9-31.5) followed by “consumption route” (RI 25.8%; 95% CI 20.7-30.9) and “administration frequency” (RI 15.2%; 95% CI 12.0-18.4). “Monitoring dosing options” was the least important attribute (RI 6.3%; 95% CI 5.2-7.4). Respondents had 63% possibility to choose a treatment profile that has factor VIII product compared with nonfactor product.</p></div><div><h3>Conclusions</h3><p>Patients and caregivers valued “type of treatment and risk of thromboembolic events” as the most important driver in choosing a treatment for moderate or severe hemophilia A. This study provides important insights into patients’ preferences and informs clinicians to consider patients’ choices when prescribing a treatment.</p></div>","PeriodicalId":23497,"journal":{"name":"Value in health regional issues","volume":"45 ","pages":"Article 101035"},"PeriodicalIF":1.4,"publicationDate":"2024-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2212109924000682/pdfft?md5=eece8a4c30e36a203836a47cc0ac3c96&pid=1-s2.0-S2212109924000682-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142083196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Population Norms and Disutility Catalog for Chronic Conditions in Sri Lanka","authors":"Nilmini Wijemunige MPH ,&nbsp;Anuji Gamage MD (Community Medicine) ,&nbsp;Ravindra P. Rannan-Eliya DPH ,&nbsp;Sanjeewa Kularatna PhD","doi":"10.1016/j.vhri.2024.101033","DOIUrl":"10.1016/j.vhri.2024.101033","url":null,"abstract":"<div><h3>Objectives</h3><p>This study aimed to produce Sri Lankan population norms of utility values, EuroQol visual analog scale scores, and reported problems in each domain of the EQ-5D-5L, as well as a disutility catalog, based on a representative set of Sri Lankan preferences.</p></div><div><h3>Methods</h3><p>Data from a nationally representative sample of 6415 adults from the Sri Lanka Health and Ageing Study in 2018 to 2019 were used. Sri Lankan preferences were applied to EQ-5D-5L scores to produce utility values. Descriptive statistics were produced for responses by EQ-5D-5L dimension, mean utility values, and EuroQol visual analog scale scores, disaggregated by demographic and disease group. Multivariable logistic regression assessed associations with problems in each dimension, and demographic and chronic diseases. Robust ordinary least squares and tobit regressions were performed to estimate the marginal disutility of demographic covariates and disease conditions.</p></div><div><h3>Results</h3><p>The mean utility value for the overall population was 0.867. Utility values decreased with age and increased with increasing education and richer socioeconomic quintiles. Males had higher utility values than females (0.89 vs 0.84; <em>P &lt;</em> .001). Utility values declined by 0.007 with each year increase in age (<em>P &lt;</em> .001) and statistically significant differences (<em>P &lt;</em> .05) in utility were found by ethnicity, socioeconomic quintile, and disease conditions such as stroke, diabetes, cancer, depression, and musculoskeletal conditions, using a tobit regression.</p></div><div><h3>Conclusions</h3><p>This study provides the first nationally representative set of population norms based on a local value set for key demographic groups and selected chronic disease conditions for Sri Lanka. It also provides a catalog that can be easily used to calculate quality-adjusted life-years for cost-utility analysis when modeling public health interventions.</p></div>","PeriodicalId":23497,"journal":{"name":"Value in health regional issues","volume":"45 ","pages":"Article 101033"},"PeriodicalIF":1.4,"publicationDate":"2024-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2212109924000669/pdfft?md5=d722ea825505d1ca571165169318b1ec&pid=1-s2.0-S2212109924000669-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142075795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychometric Evaluation of the Bengali Short Form 12 Version 2 Health Survey in Patients With Inflammatory Bowel Disease","authors":"SM Ali Hasan MD ,&nbsp;Chanchal K. Ghosh MD ,&nbsp;Abdur R. Miah MD ,&nbsp;Md Anwarul Kabir MD","doi":"10.1016/j.vhri.2024.101036","DOIUrl":"10.1016/j.vhri.2024.101036","url":null,"abstract":"<div><h3>Objectives</h3><p>Inflammatory bowel disease (IBD), comprising Crohn’s disease and ulcerative colitis, significantly affects health-related quality of life (HRQOL). Despite the widespread use of the Short Form 12 version 2 (SF-12v2) questionnaire to assess HRQOL, its validity and reliability in Bengali IBD populations remain unclear. Our study aimed to evaluate the ability of the Bengali SF-12v2 to predict HRQOL in individuals with IBD.</p></div><div><h3>Methods</h3><p>Through a cross-sectional survey, we evaluated the Bengali SF-12v2’s reliability and validity in 150 patients with IBD, with a mean age of 34 years, including 67 with Crohn’s disease and 83 with ulcerative colitis.</p></div><div><h3>Results</h3><p>A 2-factor model comprising physical and mental aspects was supported by confirmatory factor analysis. The 2-factor model demonstrated adequate goodness-of-fit indices (chi-square 96.49 [df 51]; goodness-of-fit index 0.903; adjusted goodness-of-fit index 0.851; normed fit index 0.929; comparative fit index 0.965; Tucker-Lewis index 0.954; root mean square error of approximation 0.077 [90% CI 0.053-0.101]; and standard root mean square residual 0.04). All standardized estimates were statistically significant. Item-scale correlations ranged considerably from 0.87 to 1.00, surpassing alternative item-scale correlations. Bengali SF-12v2 scores effectively identified subgroups of IBD based on disease severity. Internal consistency reliability was deemed acceptable, with Cronbach’s alpha values of 0.889 for the physical component summary and 0.904 for the mental component summary. Intraclass correlation coefficients exceeded 0.8 in all domains. A ceiling effect was observed only for bodily pain (41.3%).</p></div><div><h3>Conclusions</h3><p>The Bengali SF-12v2 was shown to have adequate psychometric validity in patients with IBD. The findings support the Bengali SF-12v2’s future usage among individuals with IBD.</p></div>","PeriodicalId":23497,"journal":{"name":"Value in health regional issues","volume":"45 ","pages":"Article 101036"},"PeriodicalIF":1.4,"publicationDate":"2024-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2212109924000694/pdfft?md5=8ece7fe941871d5d2090c783607d4886&pid=1-s2.0-S2212109924000694-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142075948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Changes in Health Spending During the COVID-19 Pandemic by Expenditure Type and Household Profiles in Mexican Households","authors":"María I. Lara Msc ,&nbsp;Monserrat Serio PhD","doi":"10.1016/j.vhri.2024.101032","DOIUrl":"10.1016/j.vhri.2024.101032","url":null,"abstract":"<div><h3>Objective</h3><p>This study aimed to analyze the changes in the health expenditure of households in Mexico during the COVID-19 pandemic to approximate changes in healthcare that can lead to difficulties in detecting noncommunicable diseases, among others.</p></div><div><h3>Methods</h3><p>We compare health spending before and after the pandemic through various estimators using multivariate linear regression models at the household level. We also explore heterogeneous effects by zone, sex, and household composition by age. We explore potential mechanisms of change estimating probit models of healthcare. We use microdata from the National Health and Nutrition Survey 2018 and COVID-19.</p></div><div><h3>Results</h3><p>The results suggest a significant reduction in health spending, mainly referring to oral health, clinical analysis, and medical studies. Moreover, differences arise by type of area and household age profile. Changes are more significant among families with children younger than 12 years and households situated in urban areas. Regarding the mechanisms, the results suggest that the lower spending is not due to fewer health needs but rather due to less healthcare attention.</p></div><div><h3>Conclusion</h3><p>The COVID-19 pandemic had a significant and heterogeneous impact on household health spending. This lower spending could lead to less detection of noncommunicable diseases, translating into more pressure on the health system in the medium and long term.</p></div>","PeriodicalId":23497,"journal":{"name":"Value in health regional issues","volume":"44 ","pages":"Article 101032"},"PeriodicalIF":1.4,"publicationDate":"2024-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142075968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing the Impact of a Designated Pharmacist Intervention on Drug Treatment Costs and Technical Efficiency in the Hemato-Oncology Outpatient Clinic","authors":"Areen Khateeb Alabbasi BPharm, MHA ,&nbsp;Shai Cohen MD ,&nbsp;Manfred S. Green MD, PhD ,&nbsp;Meir Preis MD ,&nbsp;Shmuel Klang PhD ,&nbsp;Shuli Brammli-Greenberg PhD","doi":"10.1016/j.vhri.2024.101034","DOIUrl":"10.1016/j.vhri.2024.101034","url":null,"abstract":"<div><h3>Objectives</h3><p>This study aimed to investigate the impact of a designated pharmacist (DPha) intervention in a hemato-oncology unit, focusing on reducing drug treatment costs and improving technical efficiency (TE).</p></div><div><h3>Methods</h3><p>Data from an 8-month intervention in the Israeli Clalit Health Services hemato-oncology outpatient unit were analyzed. During the study, the DPha reviewed the drug therapies being administered. After the review, a recommendation letter was sent, if relevant, to the treating physician. Data on drug treatment costs and interventions were meticulously collected and analyzed from the perspective of the insurer. A simple design was used to assess the DPha intervention’s contribution to TE and cost reduction, which was used to generate credible and transparent estimates. Sensitivity analyses were conducted to assess the robustness of 2 major variables: drug prices and pharmacist salaries.</p></div><div><h3>Results</h3><p>Over 8 months, DPha interventions led to a $279 191 cost reduction for 91 patients, resulting in net savings of $269 420 ($2960 per patient). Noteworthy is the $411 savings for each hour worked by the pharmacist, with a major impact on medications not insurer approved for the patient’s condition ($101 151) and discontinuing inappropriate medications ($52 681). Biological drug optimization accounted for 81% of total savings. Sensitivity analyses demonstrated significant cost savings across various drug prices and pharmacist salary scenarios.</p></div><div><h3>Conclusions</h3><p>The study proposes a practical framework for optimizing pharmacist services and reducing the inappropriate use of costly oncology medications. Incorporating a DPha enhances TE and yields significant cost reductions, offering valuable insights for insurers, policy makers, and healthcare professionals.</p></div>","PeriodicalId":23497,"journal":{"name":"Value in health regional issues","volume":"44 ","pages":"Article 101034"},"PeriodicalIF":1.4,"publicationDate":"2024-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142049253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}