Tropical biomedicine最新文献

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Gastrointestinal Parasites in Asian and African Elephants: A Systematic Review. 亚洲象和非洲象胃肠道寄生虫:系统综述。
IF 0.8 4区 医学
Tropical biomedicine Pub Date : 2023-03-01 DOI: 10.47665/tb.40.1.012
Z Qurratul-Saadah, A Che-Amat, S S Syed-Hussain, J Kamaludden, S M Z Ariffin, N H Basripuzi, A A Nor-Azlina
{"title":"Gastrointestinal Parasites in Asian and African Elephants: A Systematic Review.","authors":"Z Qurratul-Saadah,&nbsp;A Che-Amat,&nbsp;S S Syed-Hussain,&nbsp;J Kamaludden,&nbsp;S M Z Ariffin,&nbsp;N H Basripuzi,&nbsp;A A Nor-Azlina","doi":"10.47665/tb.40.1.012","DOIUrl":"https://doi.org/10.47665/tb.40.1.012","url":null,"abstract":"<p><p>Gastrointestinal parasites (GIPs) in elephants have been reported in several studies over the last decades. Nonetheless, comprehensive data on clinicopathology of elephant GIPs, parasite burden threshold value, and the effectiveness of conventional anthelmintic drugs are still lacking. Herein, we have systematically reviewed the available knowledge on elephant GIPs identified among different parts of the world based on their prevalence, epidemiology, pathology, diagnosis, treatment, and control. Two electronic databases were searched for publications that met the inclusion criteria. About19 English journal articles published between year of 2011- 2021 were included. The main GIPs reported in elephants were Cyathostomidae (at least 14 species), Ancylostomidae, Haemonchus contortus, Trichostrongylus colubriformis, Oesophagostomum columbianum, Oesophagostomum aceleatum, Ascarids, Trichurids, Strongyloides, Anophlocephalidae, flukes, and Coccidia across different parts of the world, including Malaysia, Indonesia, Thailand, Myanmar, Sri Lanka, India, Kenya, Nigeria, and South Africa. Most elephants show no clinical signs until the equilibrium between parasite and host is disturbed. The common diagnostic methods for GIPs are traditional direct smear, faecal floatation, sedimentation, and McMaster egg counting technique, all involving morphological identification. However, some articles described the use of molecular detection to characterise common GIPs of elephants. Although benzimidazoles and macrocyclic lactones group of anthelmintic are the most conventional GIPs treatment and control for captive and semi-captive elephants, there is limited data on the threshold value of faecal egg count as the baseline for treatment decision. Over the last decades, various studies regarding elephant GIPs have been conducted. However, more focused and systematic studies are required to enhance our knowledge in multiple aspects of elephant parasitology to find effective solutions and improve elephant health.</p>","PeriodicalId":23476,"journal":{"name":"Tropical biomedicine","volume":"40 1","pages":"55-64"},"PeriodicalIF":0.8,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9686033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chlorogenic acid derived from Moringa oleifera leaf as a potential antiinflammatory agent against cryptosporidiosis in mice. 辣木叶绿原酸对小鼠隐孢子虫病的潜在抗炎作用。
IF 0.8 4区 医学
Tropical biomedicine Pub Date : 2023-03-01 DOI: 10.47665/tb.40.1.010
R S Hamad, F El Sherif, N K Al Abdulsalam, H I Abd El-Moaty
{"title":"Chlorogenic acid derived from Moringa oleifera leaf as a potential antiinflammatory agent against cryptosporidiosis in mice.","authors":"R S Hamad,&nbsp;F El Sherif,&nbsp;N K Al Abdulsalam,&nbsp;H I Abd El-Moaty","doi":"10.47665/tb.40.1.010","DOIUrl":"https://doi.org/10.47665/tb.40.1.010","url":null,"abstract":"<p><p>Cryptosporidiosis is a serious illness in immunodeficient patients, and there is still no drug that can completely remove the parasite from the host. The present study represents the first report investigating the impact of the active molecule chlorogenic acid (CGA), naturally isolated from Moringa oleifera leaf extract (EMOLE), on immunosuppressed, Cryptosporidium parvum-infected BALB/c mice. Mice were divided into five groups: normal mice, infected immunosuppressed mice, and infected immunosuppressed mice treated with EMOLE, CGA, and nitazoxanide (NTZ) drugs. Parasitological, immunological, and histopathological investigations were recorded besides differences in the mice' body weight. Infected control mice showed elevated levels of oocyst shedding throughout the study. The EMOLE- and CGA-treated groups showed 84.2% and 91.0% reductions in oocyst shedding, respectively, with no significant difference compared to the drug control. The inflammatory markers IFN-γ, IL-6, IL-1β, and TNF-α were significantly higher in the infected control group. Treatment with 300 mg/kg/day of EMOLE or 30 mg/kg/day of CGA significantly downregulated pro-inflammatory cytokine levels compared to the infected group, although they did not change significantly compared to the NTZ-treated group. Histopathology of intestinal sections showed inflammatory and pathological changes in the infected control group. Low-grade tissue changes and an obvious improvement in villi structure were seen in mice treated with CGA. This study highlighted the role of CGA, isolated and purified from EMOLE, as an effective anti-inflammatory agent in eradicating C. parvum infection.</p>","PeriodicalId":23476,"journal":{"name":"Tropical biomedicine","volume":"40 1","pages":"45-54"},"PeriodicalIF":0.8,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9691819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Immature platelet fraction as a useful marker in Crimean-Congo hemorrhagic fever. 未成熟血小板分数作为克里米亚-刚果出血热的有用标志物。
IF 0.8 4区 医学
Tropical biomedicine Pub Date : 2023-03-01 DOI: 10.47665/tb.40.1.016
Z C Ozmen, K Deveci, U S S Coskun, Z Ozmen, L Aydogan, H S Barut
{"title":"Immature platelet fraction as a useful marker in Crimean-Congo hemorrhagic fever.","authors":"Z C Ozmen,&nbsp;K Deveci,&nbsp;U S S Coskun,&nbsp;Z Ozmen,&nbsp;L Aydogan,&nbsp;H S Barut","doi":"10.47665/tb.40.1.016","DOIUrl":"https://doi.org/10.47665/tb.40.1.016","url":null,"abstract":"<p><p>The aim of this study is to evaluate the clinical significance and diagnostic performance of the immature platelet fraction (%IPF) in Crimean-Congo hemorrhagic fever (CCHF). Samples obtained from 32 healthy control subjects and 40 CCHF patients (9 positive and 31 negative radiological findings) were evaluated in the study. The samples obtained from CT-positive subjects demonstrated higher IPF% values which also exhibited a positive correlation with mean platelet volume (MPV) and platelet size deviation width (PDW) values.The patient group IPF% values were positively correlated with the duration of hospital stay. The ROC analysis also suggested the potential importance of IPF values higher than 10.5% in diagnosing CCHF patients with positive radiological findings.The results of our study showed that % IPF can be considered as a useful parameter in the follow-up of the disease course in patients with CCHF.</p>","PeriodicalId":23476,"journal":{"name":"Tropical biomedicine","volume":"40 1","pages":"101-107"},"PeriodicalIF":0.8,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9686034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Morphological and genetic analyses of Simulium (Gomphostilbia) okinawense Takaoka and S. (G.) tokarense Takaoka (Diptera: Simuliidae) from the Nansei Islands, Japan: redescription and transfer from the S. ceylonicum species-group to the S. asakoae species-group. 日本西南群岛模拟蝇(Gomphostilbia)冲绳高冈和模拟蝇科模拟蝇(S. G. tokarense Takaoka)的形态和遗传分析:从S. ceylonicum种群到S. asakoae种群的重新描述和转移。
IF 0.8 4区 医学
Tropical biomedicine Pub Date : 2023-03-01 DOI: 10.47665/tb.40.1.007
H Takaoka, Y Otsuka, M Fukuda, V L Low, Z Ya'cob
{"title":"Morphological and genetic analyses of Simulium (Gomphostilbia) okinawense Takaoka and S. (G.) tokarense Takaoka (Diptera: Simuliidae) from the Nansei Islands, Japan: redescription and transfer from the S. ceylonicum species-group to the S. asakoae species-group.","authors":"H Takaoka,&nbsp;Y Otsuka,&nbsp;M Fukuda,&nbsp;V L Low,&nbsp;Z Ya'cob","doi":"10.47665/tb.40.1.007","DOIUrl":"https://doi.org/10.47665/tb.40.1.007","url":null,"abstract":"<p><p>Simulium (Gomphostilbia) okinawense Takaoka and S. (G.) tokarense Takaoka, both from the Nansei Islands, Japan, were morphologically reexamined and genetically analysed by using the COI gene sequences. The female, male, pupa and mature larva of the two species are redescribed. Morphological reexamination shows that both species are more similar to species in the S. asakoae species-group than to those in the S. ceylonicum species-group, by having a medium-long female sensory vesicle, yellow tuft hairs (S. (G.) okinawense) or yellow tuft hairs mixed with a few to several dark hairs (S. (G.) tokarense) at the base of the radial vein in the female and male, and medium-long larval postgenal cleft. However, the body of the male ventral plate (viewed ventrally) is parallel-sided (S. (G.) okinawense) or parallelsided or slightly narrowed (S. (G.) tokarense) and not emarginated basally, differing from those of most species in the S. asakoae species-group. Our genetic analysis shows that S. (G.) tokarense is in the S. asakoae species-group, and S. (G.) okinawense formed a separate sister clade with other members of the S. asakoae species-group with high bootstrap support. From the results of morphological and genetic analysis combined, S. (G.) okinawense and S. (G.) tokarense are transferred from the S. ceylonicum species-group to the S. asakoae species-group.</p>","PeriodicalId":23476,"journal":{"name":"Tropical biomedicine","volume":"40 1","pages":"88-100"},"PeriodicalIF":0.8,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9686035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Salmonella enteritidis abdominal aorta mycotic aneurysm presented with acute cholestatic jaundice: A case report and literature review. 肠炎沙门氏菌腹主动脉真菌性动脉瘤并发急性胆汁淤积性黄疸1例并文献复习。
IF 0.8 4区 医学
Tropical biomedicine Pub Date : 2023-03-01 DOI: 10.47665/tb.40.1.008
A A Wahab, N Mohamed, C H Ding, N A S Muttaqillah, N Rosli, F Mohammed
{"title":"Salmonella enteritidis abdominal aorta mycotic aneurysm presented with acute cholestatic jaundice: A case report and literature review.","authors":"A A Wahab,&nbsp;N Mohamed,&nbsp;C H Ding,&nbsp;N A S Muttaqillah,&nbsp;N Rosli,&nbsp;F Mohammed","doi":"10.47665/tb.40.1.008","DOIUrl":"https://doi.org/10.47665/tb.40.1.008","url":null,"abstract":"<p><p>Mycotic aneurysm is one of the extra-intestinal manifestations of Salmonella Enteritidis infection. The diagnosis of this condition is challenging owed to its variation in clinical presentations. We presented a case of a 54-year-old man with underlying diabetes mellitus and chronic smokers presented with acute right flank pain and fever associated with mild jaundice. The initial laboratory investigations suggested features of obstructive jaundice and urinary tract infection. The contrast enhancing computed tomography of the abdomen revealed the presence of saccular mycotic aneurysm located at the infrarenal abdominal aorta. The blood culture grew Salmonella Enteritidis which was susceptible to ceftriaxone, trimethoprim-sulfamethoxazole, ciprofloxacin, ampicillin, and amoxicillin-clavulanic acid. Intravenous ceftriaxone was initiated, and he underwent open surgery and artery repair at day 8 of admission. He responded well to the treatment given and subsequently discharged home after completed three weeks of intravenous ceftriaxone.</p>","PeriodicalId":23476,"journal":{"name":"Tropical biomedicine","volume":"40 1","pages":"23-28"},"PeriodicalIF":0.8,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9691815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Poverty related diseases amongst Malaysia's low-income community: a review. 马来西亚低收入社区中与贫穷有关的疾病:审查。
IF 0.8 4区 医学
Tropical biomedicine Pub Date : 2023-03-01 DOI: 10.47665/tb.40.1.013
N Abu Bakar, N Sahimin, Y A L Lim, K Ibrahim, S N Mohd Zain
{"title":"Poverty related diseases amongst Malaysia's low-income community: a review.","authors":"N Abu Bakar,&nbsp;N Sahimin,&nbsp;Y A L Lim,&nbsp;K Ibrahim,&nbsp;S N Mohd Zain","doi":"10.47665/tb.40.1.013","DOIUrl":"https://doi.org/10.47665/tb.40.1.013","url":null,"abstract":"<p><p>Poverty, as proven by several studies, is a driving force behind poor health and hygiene practices. This review attempts to outline common communicable and non-communicable diseases that disproportionately affect Malaysia's 2.91 million low-income households. The current study also looks into the government's housing and healthcare programmes for this demographic to improve their health and well-being. The initial examination yielded incredibly little research on this marginalised community, with event reporting typically generalised to the Malaysian community as a whole rather than analysing disease incidences based on household income, which would better reflect povertydriven diseases. As a result, there is an acute need for more accurate information on the epidemiology of diseases among the poor in order to address this public health issue and provide conclusions that can drive policy designs.</p>","PeriodicalId":23476,"journal":{"name":"Tropical biomedicine","volume":"40 1","pages":"65-75"},"PeriodicalIF":0.8,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9686031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Genetic diversity of secreted protein with an altered thrombospondin repeat (SPATR) of Plasmodium knowlesi clinical isolates from Malaysia. 马来西亚诺氏疟原虫临床分离株伴血小板反应蛋白重复序列改变的分泌蛋白遗传多样性
IF 0.8 4区 医学
Tropical biomedicine Pub Date : 2022-12-01 DOI: 10.47665/tb.39.4.006
U W Azlan, Y L Lau, M H A Hamid, J Jelip, C H Ooi, R N Mudin, J J Jaimin, M Y Fong
{"title":"Genetic diversity of secreted protein with an altered thrombospondin repeat (SPATR) of Plasmodium knowlesi clinical isolates from Malaysia.","authors":"U W Azlan,&nbsp;Y L Lau,&nbsp;M H A Hamid,&nbsp;J Jelip,&nbsp;C H Ooi,&nbsp;R N Mudin,&nbsp;J J Jaimin,&nbsp;M Y Fong","doi":"10.47665/tb.39.4.006","DOIUrl":"https://doi.org/10.47665/tb.39.4.006","url":null,"abstract":"<p><p>The Plasmodium knowlesi secreted protein with an altered thrombospondin repeat (PkSPATR) is an important protein that helps in the parasite's invasion into the host cell. This protein has been regarded as one of the potential vaccine candidates against P. knowlesi infection. This study investigates the genetic diversity and natural selection of PkSPATR gene of P. knowlesi clinical isolates from Malaysia. PCR amplification of the full length PkSPATR gene was performed on 60 blood samples of infected P. knowlesi patients from Peninsular Malaysia and Malaysian Borneo. The amplified PCR products were cloned and sequenced. Sequence analysis of PkSPATR from Malaysia showed higher nucleotide diversity (CDS p: 0.01462) than previously reported Plasmodium vivax PvSPATR (p = 0.0003). PkSPATR from Peninsular Malaysia was observed to have slightly higher diversity (CDS p: 0.01307) than those from Malaysian Borneo (CDS p: 0.01212). Natural selection analysis on PkSPATR indicated significant purifying selection. Multiple amino acid sequence alignment revealed 69 polymorphic sites. The phylogenetic tree and haplotype network did not show any distinct clustering of PkSPATR. The low genetic diversity level, natural selection and absence of clustering implied functional constrains of the PkSPATR protein.</p>","PeriodicalId":23476,"journal":{"name":"Tropical biomedicine","volume":"39 4","pages":"504-510"},"PeriodicalIF":0.8,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10489762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Lactic acid bacteria waste infusion as a source of attraction and oviposition stimulation of gravid female Aedes albopictus mosquitoes. 乳酸菌废物输注对妊娠雌白纹伊蚊的吸引和产卵刺激作用。
IF 0.8 4区 医学
Tropical biomedicine Pub Date : 2022-12-01 DOI: 10.47665/tb.39.4.004
M M Suria, P C Yap, V L Lov, S AbuBakar, H Y Lee
{"title":"Lactic acid bacteria waste infusion as a source of attraction and oviposition stimulation of gravid female Aedes albopictus mosquitoes.","authors":"M M Suria,&nbsp;P C Yap,&nbsp;V L Lov,&nbsp;S AbuBakar,&nbsp;H Y Lee","doi":"10.47665/tb.39.4.004","DOIUrl":"https://doi.org/10.47665/tb.39.4.004","url":null,"abstract":"<p><p>Aedes albopictus poses a public health risk in tropical countries and temperate countries in recent decades due to its capability to transmit various human arboviruses including dengue, yellow fever, and chikungunya. Vector control is the key for preventing transmission of these pathogenic viruses. Improving the effectiveness of currently utilized collection methods, such as ovitraps, is important for best species abundance monitoring, assessment of the threat of arbovirus transmission, and optimizing control activities. Therefore, this study aimed to assess the potential use of lactic acid bacteria (LAB) waste as an infusion-baited ovitrap for Aedes collection. The performance of overnight tap water, grass hay infusion and LAB waste infusion were compared for their ability in attracting gravid female Ae. albopictus. In this study, the LAB waste infusion was substantially more alluring to Ae. albopictus mosquitoes than the two controls grass hay infusion and tap water.</p>","PeriodicalId":23476,"journal":{"name":"Tropical biomedicine","volume":"39 4","pages":"499-503"},"PeriodicalIF":0.8,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10489768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Phytochemical composition of almond oil from Melia azedarach L. and its larvicidal, ovicidal, repellent and enzyme activities in Culex pipiens L. 苦楝杏仁油的植物化学成分及其对库蚊的杀幼、杀卵、驱避和酶活性研究
IF 0.8 4区 医学
Tropical biomedicine Pub Date : 2022-12-01 DOI: 10.47665/tb.39.4.008
R Khaldi, N Rehimi, R Kharoubi, N Soltani
{"title":"Phytochemical composition of almond oil from Melia azedarach L. and its larvicidal, ovicidal, repellent and enzyme activities in Culex pipiens L.","authors":"R Khaldi,&nbsp;N Rehimi,&nbsp;R Kharoubi,&nbsp;N Soltani","doi":"10.47665/tb.39.4.008","DOIUrl":"https://doi.org/10.47665/tb.39.4.008","url":null,"abstract":"<p><p>Melia azedarach L. (Meliaceae) is a botanical species with focal point of global research for its biological properties. The Melia azedarach tree is distinguished by its rapid growth, its adaptation to different temperate zones, as well as its insecticidal properties. All this made us think of exploiting it in biological control against different stages of mosquitoes. To this end, we aim, through the present work, to evaluate the effectiveness of Melia azedarach extracts against Culex pipiens mosquito. More specifically, our study focuses on determining the chemical composition of Melia almond oil, as well as the larvicidal, ovicidal and repellent activities on Culex pipiens L. mosquito as well as the activities of acetylcholinesterase (AChE) and glutathione-S-transferase (GST). Almond oil was extracted by a Soxhlet and subjected to gas chromatography-mass spectrometry (GC/MS). The yield was found to be 35.17%. The chemical composition revealed the presence of various phytoconstituents. A total of 7 compounds were identified, the main ones being 9,11-Octadecadienoic acid, methyl ester, (E,E)- (79.32%), 9-octadecenoic acid (Z)-, methyl ester (13.24%), hexadecanoic acid and methyl ester (3.69%). The larvicidal bioassays were performed according to the protocol recommended by the World Health Organization with concentrations varying from 20 to 80 mg/L depending on the exposure time (24, 48 and 72 hours). The almond oil exhibited remarkable larvicidal activity against fourth instar larvae and the lethal concentrations were determined (LC<sub>25</sub>= 23.70 mg/L, LC<sub>50</sub>=35.49 mg/L, LC<sub>90</sub>=79.61 mg/L). The results also showed that the oil caused an ovicidal activity with a significant effect on egg hatch. The recorded hatching percentages were respectively 88.79% and 72.40% for the LC<sub>25</sub> and LC<sub>50</sub>, and this compared to the control series. Moreover, this oil exhibited significant repellency against adult mosquitoes. Furthermore, the enzymatic measurements performed on LC<sub>50</sub> and LC<sub>90</sub> treated larvae revealed a neurotoxic activity and a stimulation of the detoxification system as evidenced, respectively, by an inhibition of AChE and induction in GST activity. Overall, our data proved that Melia azedarach almond oil could be considered as a potent biorational alternative to synthetic insecticides for mosquito control.</p>","PeriodicalId":23476,"journal":{"name":"Tropical biomedicine","volume":"39 4","pages":"531-538"},"PeriodicalIF":0.8,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10489769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
First molecular report of Babesia gibsoni infection in pet dogs in Hunan province, subtropical China. 湖南省宠物犬感染巴贝斯虫的首次分子报告。
IF 0.8 4区 医学
Tropical biomedicine Pub Date : 2022-12-01 DOI: 10.47665/tb.39.4.007
S G Tan, P Y Xu
{"title":"First molecular report of Babesia gibsoni infection in pet dogs in Hunan province, subtropical China.","authors":"S G Tan,&nbsp;P Y Xu","doi":"10.47665/tb.39.4.007","DOIUrl":"https://doi.org/10.47665/tb.39.4.007","url":null,"abstract":"<p><p>Canine babesiosis caused by Babesia spp. is a noteworthy tick-borne zoonotic disease of domestic dogs and wild canids. In present study, a total of 556 blood samples were randomly collected from pet dogs in eight cities of Hunan province, subtropical China. Genomic DNA was extracted and Babesia DNA was detected by amplification of partial 18S rRNA gene sequences. A total of 56 (10.1%) blood samples were tested positive for Babesia species. Sequence analysis showed that 29 dogs (5.2%) were positive for B. gibsoni, and other 27 dogs for B. vogeli (4.9%). The age and health status were considered as important risk factors for B. gibsoni and B. vogeli infections in pet dogs in this study (P<0.05). Phylogenetic analysis showed that the examined positive samples were highly clustered in the same branch with B. gibsoni and B. vogeli, respectively. This is the first molecular report of B. gibsoni infection in pet dogs in Hunan province, subtropical China. Our finding has provided a guide for the control of dog babesiosis in China and elsewhere.</p>","PeriodicalId":23476,"journal":{"name":"Tropical biomedicine","volume":"39 4","pages":"524-530"},"PeriodicalIF":0.8,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10489766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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