Immature platelet fraction as a useful marker in Crimean-Congo hemorrhagic fever.

IF 0.8 4区 医学 Q4 PARASITOLOGY
Z C Ozmen, K Deveci, U S S Coskun, Z Ozmen, L Aydogan, H S Barut
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引用次数: 0

Abstract

The aim of this study is to evaluate the clinical significance and diagnostic performance of the immature platelet fraction (%IPF) in Crimean-Congo hemorrhagic fever (CCHF). Samples obtained from 32 healthy control subjects and 40 CCHF patients (9 positive and 31 negative radiological findings) were evaluated in the study. The samples obtained from CT-positive subjects demonstrated higher IPF% values which also exhibited a positive correlation with mean platelet volume (MPV) and platelet size deviation width (PDW) values.The patient group IPF% values were positively correlated with the duration of hospital stay. The ROC analysis also suggested the potential importance of IPF values higher than 10.5% in diagnosing CCHF patients with positive radiological findings.The results of our study showed that % IPF can be considered as a useful parameter in the follow-up of the disease course in patients with CCHF.

未成熟血小板分数作为克里米亚-刚果出血热的有用标志物。
本研究的目的是评价未成熟血小板分数(%IPF)在克里米亚-刚果出血热(CCHF)中的临床意义和诊断价值。本研究对32名健康对照者和40名CCHF患者(9名放射学结果为阳性,31名放射学结果为阴性)的样本进行了评估。ct阳性受试者的样本显示更高的IPF%值,并且与平均血小板体积(MPV)和血小板大小偏差宽度(PDW)值呈正相关。患者组IPF%值与住院时间呈正相关。ROC分析还提示IPF值高于10.5%对于诊断放射学阳性的CCHF患者的潜在重要性。我们的研究结果表明,% IPF可以被认为是CCHF患者病程随访的一个有用参数。
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来源期刊
Tropical biomedicine
Tropical biomedicine 医学-寄生虫学
CiteScore
1.60
自引率
0.00%
发文量
63
审稿时长
6-12 weeks
期刊介绍: The Society publishes the Journal – Tropical Biomedicine, 4 issues yearly. It was first started in 1984. The journal is now abstracted / indexed by Medline, ISI Thompson, CAB International, Zoological Abstracts, SCOPUS. It is available free on the MSPTM website. Members may submit articles on Parasitology, Tropical Medicine and other related subjects for publication in the journal subject to scrutiny by referees. There is a charge of US$200 per manuscript. However, charges will be waived if the first author or corresponding author are members of MSPTM of at least three (3) years'' standing.
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