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The Risk of Thrombotic Events in Anetoderma Affecting Young Patients 影响年轻患者的无乳皮病血栓事件的风险
Journal of Interdisciplinary Medicine Pub Date : 2021-06-01 DOI: 10.2478/jim-2020-0029
A. Chiriac, M. Betiu, C. Podoleanu, S. Stolnicu
{"title":"The Risk of Thrombotic Events in Anetoderma Affecting Young Patients","authors":"A. Chiriac, M. Betiu, C. Podoleanu, S. Stolnicu","doi":"10.2478/jim-2020-0029","DOIUrl":"https://doi.org/10.2478/jim-2020-0029","url":null,"abstract":"Abstract Anetoderma is a rare skin disease, and its associated risk of thromboembolic events is unknown. Anetoderma is characterized by focal injury of elastic fibers in the dermis, clinically expressed by atrophic skin lesions. We report the case of a young person with anetoderma, drawing attention to the risk of associated thromboembolic peril.","PeriodicalId":234618,"journal":{"name":"Journal of Interdisciplinary Medicine","volume":"144 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123474737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ilio-Deep Femoral Bypass – an Alternative Treatment Strategy to Critical Limb Ischemia (CLI) 髂深股旁路治疗重度肢体缺血(CLI)的另一种治疗策略
Journal of Interdisciplinary Medicine Pub Date : 2021-06-01 DOI: 10.2478/jim-2021-0021
Vasile Adrian Mureșan, M. Cosarca, E. Russu, R. Niculescu, Mihai Soimu
{"title":"Ilio-Deep Femoral Bypass – an Alternative Treatment Strategy to Critical Limb Ischemia (CLI)","authors":"Vasile Adrian Mureșan, M. Cosarca, E. Russu, R. Niculescu, Mihai Soimu","doi":"10.2478/jim-2021-0021","DOIUrl":"https://doi.org/10.2478/jim-2021-0021","url":null,"abstract":"Abstract Background: Critical limb ischemia is considered the most severe form of peripheral artery disease. High morbidity and mortality rates are associated with this pathology due to poor economic management of complications. Case summary: A 68-year-old female patient underwent a routine Doppler ultrasound which revealed the obstruction of both the common and superficial right femoral arteries, as well as the right deep femoral artery. In this case, an iliofemoral bypass was performed using the right deep femoral artery as the outflow artery. Conclusion: Revascularization of the deep femoral artery has a reasonable chance of preserving the ischemic lower limb whenever the common and superficial femoral arteries suffer major atherosclerotic blockages.","PeriodicalId":234618,"journal":{"name":"Journal of Interdisciplinary Medicine","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128504226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Gasping on Oxygen: A Case Report on Toxic Methemoglobinemia 氧气窒息:中毒性高铁血红蛋白血症1例报告
Journal of Interdisciplinary Medicine Pub Date : 2021-06-01 DOI: 10.2478/jim-2021-0001
M. Sahadevan, M. Mahendran, Subasini Govindan, Thilagavathi Thanusia Viswanathan
{"title":"Gasping on Oxygen: A Case Report on Toxic Methemoglobinemia","authors":"M. Sahadevan, M. Mahendran, Subasini Govindan, Thilagavathi Thanusia Viswanathan","doi":"10.2478/jim-2021-0001","DOIUrl":"https://doi.org/10.2478/jim-2021-0001","url":null,"abstract":"Abstract We report the case of a 27-year-old male patient who presented with refractory hypoxemia following the alleged inhalation of an unknown substance. The patient appeared to show worsening cyanosis despite increment of supplemental oxygenation. A drawn sample of the patient’s blood appeared chocolate brown in color, and disparity was noted between the patient’s oxygen saturation (SaO2) in his blood against the pulse oximetry (SpO2) reading. A diagnosis of toxic methemoglobinemia was established following elevated levels of methemoglobin discovered in his blood. The patient was started on methylene blue and instantaneously recovered without any complications. Methemoglobinemia should be suspected in any patient with refractory cyanosis, and early recognition of this condition could be potentially lifesaving.","PeriodicalId":234618,"journal":{"name":"Journal of Interdisciplinary Medicine","volume":"35 10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125720063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Review of Anti-C Reactive Protein Antibodies in Systemic Lupus Erythematosus 系统性红斑狼疮抗c反应蛋白抗体研究进展
Journal of Interdisciplinary Medicine Pub Date : 2021-06-01 DOI: 10.2478/jim-2021-0017
P. Richter, A. Burlui, I. Bratoiu, A. Cardoneanu, C. Rezus, E. Rezus
{"title":"A Review of Anti-C Reactive Protein Antibodies in Systemic Lupus Erythematosus","authors":"P. Richter, A. Burlui, I. Bratoiu, A. Cardoneanu, C. Rezus, E. Rezus","doi":"10.2478/jim-2021-0017","DOIUrl":"https://doi.org/10.2478/jim-2021-0017","url":null,"abstract":"Abstract Systemic lupus erythematosus (SLE), the prototype autoimmune disease, is characterized by the production of a plethora of autoantibodies with various roles in the development of disease-related tissue damage. C-reactive protein (CRP) is an acute phase reactant with a pentameric structure. Under acidic or alkaline conditions, or when urea levels are high and/or calcium levels are low, the pentamer (pCRP) dissociates irreversibly into monomeric CRP (mCRP) and exposes new epitopes (neo-CRP). Importantly, anti-mCRP (but not anti-pCRP) antibodies have been described in patients with SLE, their prevalence varying from 4% to 78% in different cohorts. Numerous studies have investigated the relationship between autoantibodies directed against CRP (anti-CRP) and disease activity as well as their association with lupus nephritis (LN), frequently reporting discrepant findings. The main objective of the present review is to describe the role of anti-mCRP antibodies in SLE according to the currently available data.","PeriodicalId":234618,"journal":{"name":"Journal of Interdisciplinary Medicine","volume":"116 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132072145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Malaria and Insecticide-Treated Net (ITN) Utilization among Orphans and Vulnerable Children in Nigeria 尼日利亚孤儿和弱势儿童使用疟疾和驱虫蚊帐的情况
Journal of Interdisciplinary Medicine Pub Date : 2021-06-01 DOI: 10.2478/jim-2021-0012
Oyetunde T. Oyeyemi, K. M. Akinseye, Iyanuoluwa I. Odewuyi, Rashidat O. Olayinka, Oluwasegun E. Ajibawo, Imoleayo A. Ogunleye, Ifeoluwa I. Oyeyemi
{"title":"Malaria and Insecticide-Treated Net (ITN) Utilization among Orphans and Vulnerable Children in Nigeria","authors":"Oyetunde T. Oyeyemi, K. M. Akinseye, Iyanuoluwa I. Odewuyi, Rashidat O. Olayinka, Oluwasegun E. Ajibawo, Imoleayo A. Ogunleye, Ifeoluwa I. Oyeyemi","doi":"10.2478/jim-2021-0012","DOIUrl":"https://doi.org/10.2478/jim-2021-0012","url":null,"abstract":"Abstract Background: The lack of empirical data on the malaria status of orphans and vulnerable children (OVC), access to long-lasting insecticide-treated nets (LLINs), and knowledge about the disease can hamper the development of effective policies and programs to address their malaria-related needs. Aim: The aim of this study was to evaluate knowledge of malaria transmission and utilization of LLINs among OVC in Ondo metropolis, Nigeria. Materials and Methods: A cross-sectional study was conducted in Ondo City, Ondo State, Nigeria, between January and March 2018. The study was carried out among 66 OVC (age 5–19 years) using questionnaires. Information on socio-demography, LLIN utilization, knowledge and risks of malaria transmission among OVC was sought. Results: The use of LLINs (80.9%) among OVC was significantly higher than the use of insecticide spray (6.1%) and mosquito coils (12.1%) (p <0.0001). Knowledge about malaria transmission was relatively high, and the majority of children (60.6%) believed malaria is mostly transmitted during the dry season. Fewer children (21.2%) had a history of malaria in the last 3 months. Conclusions: The risk of malaria transmission was low among OVC. Continuous accessibility of orphanage homes to LLINs should be sustained to prevent malaria transmission among OVC.","PeriodicalId":234618,"journal":{"name":"Journal of Interdisciplinary Medicine","volume":"21 2","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114105475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of an Alternative Depression Therapy Using Bioresonance 生物共振替代抑郁症治疗的评价
Journal of Interdisciplinary Medicine Pub Date : 2021-03-23 DOI: 10.2478/jim-2021-0019
D. Muresan, Andreea Sălcudean, B. Barbu, C. Bodo, I. G. Grecu
{"title":"Evaluation of an Alternative Depression Therapy Using Bioresonance","authors":"D. Muresan, Andreea Sălcudean, B. Barbu, C. Bodo, I. G. Grecu","doi":"10.2478/jim-2021-0019","DOIUrl":"https://doi.org/10.2478/jim-2021-0019","url":null,"abstract":"Abstract Background: Bioresonance therapy is a holistic physical method used in the treatment of various diseases. Aim of the study: The aim of the present paper was to evaluate the effect of bioresonance therapy in patients with recurrent major depressive disorder and with mild or moderate depressive episodes, respectively, without any other pharmacological, psychological, or other type of treatment. Methods: We selected 40 patients diagnosed with recurrent depressive disorder and bioresonance therapy as the only treatment. Assessment of the level of depression was achieved by measuring the biorhythm with the bioresonance device and by applying the Hamilton Depression Inventory questionnaire, with 17 items, at the beginning and the end of five weeks of treatment. Results: We identified a statistically significant decrease in depression levels as quantified by the HAM-D 17 scale, between the initial and final phase of therapy (p = 0.0001). Conclusions: Our results suggest that bioresonance therapy can decrease the level of depression in patients with recurrent depressive disorder, with mild and moderate depressive episodes.","PeriodicalId":234618,"journal":{"name":"Journal of Interdisciplinary Medicine","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127174932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
The Impact of Coronary Artery Calcification on Long-Term Cardiovascular Outcomes 冠状动脉钙化对长期心血管预后的影响
Journal of Interdisciplinary Medicine Pub Date : 2021-03-01 DOI: 10.2478/jim-2021-0007
N. Mitra, R. Gerculy, Evelin Szabó, D. Opincariu, M. Chițu, I. Benedek
{"title":"The Impact of Coronary Artery Calcification on Long-Term Cardiovascular Outcomes","authors":"N. Mitra, R. Gerculy, Evelin Szabó, D. Opincariu, M. Chițu, I. Benedek","doi":"10.2478/jim-2021-0007","DOIUrl":"https://doi.org/10.2478/jim-2021-0007","url":null,"abstract":"Abstract Decades of research and experimental studies have investigated various strategies to prevent acute coronary events. However, significantly efficient preventive methods have not been developed and still remains a challenge to determine if a coronary atherosclerotic plaque will become vulnerable and unstable. This review aims to assess the significance of plaque vulnerability markers, more precisely the role of spotty calcifications in the development of major cardiac events, given that coronary calcification is a hallmark of atherosclerosis. Recent studies have suggested that microcalcifications, spotty calcifications, and the presence of the napkin-ring sign are predictive vulnerable plaque features, and their presence may cause plaque instability.","PeriodicalId":234618,"journal":{"name":"Journal of Interdisciplinary Medicine","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123536392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Cardiovascular Imaging Techniques for Detection of Vulnerable Plaques 检测易损斑块的心血管成像技术
Journal of Interdisciplinary Medicine Pub Date : 2021-03-01 DOI: 10.2478/jim-2021-0008
E. Márton, D. Cernica, C. Țolescu, A. Lupsan, M. Chițu, I. Benedek
{"title":"Cardiovascular Imaging Techniques for Detection of Vulnerable Plaques","authors":"E. Márton, D. Cernica, C. Țolescu, A. Lupsan, M. Chițu, I. Benedek","doi":"10.2478/jim-2021-0008","DOIUrl":"https://doi.org/10.2478/jim-2021-0008","url":null,"abstract":"Abstract Various cardiovascular imaging techniques were developed for the detection of vulnerable atherosclerotic plaques, hoping to be able to predict a cardiovascular event. Plaque vulnerability results from compound pathophysiological mechanisms that lead to structural and morphological changes in lesions. The aim of this review is to present the most recent techniques for the assessment of vulnerable coronary plaques such as cardiac computed tomography angiography (CCTA), optical coherence tomography, or virtual histology intravascular ultra-sound, based on literature data from the last 3 years. CCTA permits direct visualization of the intravascular lumen, together with characterization of the arterial wall. Recent studies maintain that low-attenuation plaques, spotty calcifications, positive vessel remodeling, and the napkin-ring sign are considered main markers of plaque vulnerability and instability. Emerging analytical techniques, such as machine learning or radiomics, will probably demonstrate useful as an auxiliary diagnostic tool for vulnerable plaque detection. The data from the two imaging techniques together provide useful information, especially in patients undergoing a PCI procedure for an acute coronary syndrome. Invasive and noninvasive imaging techniques are able to deliver a large amount of scientific data to assess vulnerable coronary atheromatous plaques. Recent studies demonstrated that information defined by the two techniques is complementary, and using both methods is essential for adequate diagnosis, therapeutic strategy, and prognostic assessment.","PeriodicalId":234618,"journal":{"name":"Journal of Interdisciplinary Medicine","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116926879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Positive Remodeling – a Major Feature of Vulnerability in Patients with Non-Obstructive Coronary Artery Disease 正重构——非阻塞性冠状动脉疾病患者易损性的一个主要特征
Journal of Interdisciplinary Medicine Pub Date : 2021-03-01 DOI: 10.2478/jim-2021-0005
Evelin Szabó, D. Opincariu, A. Mester, A. Stănescu, N. Raț, T. Benedek
{"title":"Positive Remodeling – a Major Feature of Vulnerability in Patients with Non-Obstructive Coronary Artery Disease","authors":"Evelin Szabó, D. Opincariu, A. Mester, A. Stănescu, N. Raț, T. Benedek","doi":"10.2478/jim-2021-0005","DOIUrl":"https://doi.org/10.2478/jim-2021-0005","url":null,"abstract":"Abstract The most common cause of acute coronary syndrome is thrombosis of an atheromatous plaque. Positive remodeling is the compensatory dilatation of the plaque-containing section of the vessel wall. Plaques are most commonly characterized as vulnerable when possessing some of the following features: fibrous cap thickness <65 µm, large necrotic lipid core, high degrees of inflammatory infiltrates, positive remodeling, intraplaque hemorrhage, or neoangio-genesis. The presence of these plaque features is associated with high cardiovascular risk. In the initial stage of vasculopathy, due to positive remodeling, lumen reduction is not typical; it only develops in the advanced phase of the disease, due to which, based on a lumenogram, the vascular system may appear intact. Therefore, coronary angiography can easily miss the diagnosis or underestimate its extent, since it does not inform us of the composition of the arterial wall, because the contrast agent is just filling the vessel lumen. Coronary CT angiography may fill this diagnostic gap, since changes of the vessel wall can directly be visualized. To increase diagnostic accuracy, invasive coronary angiography can be completed by intravascular ultrasound and optical coherence tomography.","PeriodicalId":234618,"journal":{"name":"Journal of Interdisciplinary Medicine","volume":"61 3‐4","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"113954701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Management of Culprit and Non-Culprit Lesions in Acute Coronary Syndrome 急性冠脉综合征的罪魁祸首和非罪魁祸首病变的处理
Journal of Interdisciplinary Medicine Pub Date : 2021-03-01 DOI: 10.2478/jim-2021-0009
R. Gerculy, N. Mitra, Evelin Szabó, D. Opincariu, M. Chițu, I. Benedek
{"title":"Management of Culprit and Non-Culprit Lesions in Acute Coronary Syndrome","authors":"R. Gerculy, N. Mitra, Evelin Szabó, D. Opincariu, M. Chițu, I. Benedek","doi":"10.2478/jim-2021-0009","DOIUrl":"https://doi.org/10.2478/jim-2021-0009","url":null,"abstract":"Abstract Multivessel coronary artery disease, defined by the presence of a significant stenosis (≥50% diameter) in two or more epicardial coronary vessels, usually occurs in more than 50% of patients with ST-segment elevation myocardial infarction. The latest guidelines indicate revascularization of the non-culprit artery with a recommendation of class IIB. However, the management of non-culprit lesions in patients with acute coronary syndrome is still a matter of debate. This article presents the most recent concepts related to the management of culprit and non-culprit coronary lesions, based on advanced imaging approaches, in order to identify high-risk patients and prevent further acute coronary syndromes.","PeriodicalId":234618,"journal":{"name":"Journal of Interdisciplinary Medicine","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130041056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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