United European Gastroenterology Journal最新文献

{"title":"Mortality Prediction by Bedside Rectus Femoris Muscle Ultrasound for Sarcopenia Diagnosis in Liver Cirrhosis.","authors":"Sara De Monte, Philipp Altmann, Svenja Pichlmeier, Hans Benno Leicht, Sophia Stuhlreiter, Roswitha Brandl, Florian P Reiter, Sigrid Hahn, Clemens Benoit, Andreas Geier, Mathias Plauth, Monika Rau","doi":"10.1002/ueg2.70114","DOIUrl":"https://doi.org/10.1002/ueg2.70114","url":null,"abstract":"<p><strong>Background: </strong>Sarcopenia is common in patients with liver cirrhosis and is an independent predictor of morbidity and mortality. This prospective study assessed the performance of rectus femoris muscle (RFM) ultrasound in patients with liver cirrhosis to identify those at risk for sarcopenia as defined by the combination of low muscle mass and low muscle strength.</p><p><strong>Methods: </strong>84 patients with liver cirrhosis hospitalized at a tertiary center (05/22-02/24) were included with 6-month follow-up. Within 24-48 h of admission hand grip strength, chair rise test (CRT), timed up and go (TUG), short physical performance battery (SPPB), rectus femoris muscle ultrasound, and bioelectrical impedance analysis (BIA) were assessed. Statistical analyses included receiver operating characteristic (ROC) curves, Kaplan-Meier estimates, Cox regression, and competing risk analyses.</p><p><strong>Results: </strong>Most (73.8%) patients had decompensated and mainly alcohol-related liver cirrhosis. Thickness and cross-sectional area of rectus femoris muscle (MT_RFM/CSA_RFM) were significantly (p < 0.01 each) lower in more advanced disease by Child-Pugh (CP) stage, also when normalized for height². MT_RFM/height² and CSA_RFM/height² demonstrated good predictive value for BIA-derived low muscle mass (ASMI < 7/5.7 kg/m²) or low phase angle ≤ 4.9° (AUROC 0.727-0.770). Impaired physical performance, in terms of prolonged CRT and TUG test time was associated with reduced MT_RFM or CSA_RFM (p < 0.05 each), respectively. Higher muscle echogenicity correlated with poorer performance in TUG and SPPB. Low rectus femoris muscle mass was associated with shorter survival and sarcopenic (prolonged CRT and low MT_RFM/height²) patients had a high 6-month mortality risk (HR 7.188; 95% CI 2.249-22.978).</p><p><strong>Conclusion: </strong>Rectus femoris muscle ultrasound is a feasible bedside method for identifying patients with liver cirrhosis at risk of sarcopenia. Sarcopenia as diagnosed by prolonged CRT together with low RFM mass by ultrasound is an independent predictor for 6-month mortality, highlighting the clinical utility of RFM ultrasound in diagnosing sarcopenia.</p>","PeriodicalId":23444,"journal":{"name":"United European Gastroenterology Journal","volume":" ","pages":""},"PeriodicalIF":6.7,"publicationDate":"2025-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145228336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Safety and Effectiveness of Cholecystectomy and Endoscopic Retrograde Cholangiopancreatography in Biliary Pancreatitis During Pregnancy: BORN Study.","authors":"Dorottya Tarján, Eszter Ágnes Szalai, Bálint Erőss, Péter Jenő Hegyi, Vasile Liviu Drug, Serge Chooklin, Michael Hirth, Gabriel Sandblom, Vanessa Sandblom, Åsa Edergren, Ahmed Tlili, Sami Fendri, Simon Sirtl, Daniel de la Iglesia Gracía, Floreta Kurti, Dong Wu, Adriana Gherbon, Łukasz Nawacki, Alexandru Constantinescu, Natalia V Shirinskaya, Alexander N Zolotov, Sanjay Pandanaboyana, Tsukasa Ikeura, Tiago Cúrdia Gonçalves, Louise Rasmussen, Bodil Andersson, Ahmed Bouzid, Ahmed Saidani, Nándor Ács, Zoltán Sipos, Nelli Farkas, Balázs Tihanyi, Brigitta Teutsch, Johan Nilsson, Alexandra Mikó, Péter Hegyi","doi":"10.1002/ueg2.70121","DOIUrl":"https://doi.org/10.1002/ueg2.70121","url":null,"abstract":"<p><strong>Background: </strong>Biliary acute pancreatitis (AP) during pregnancy is a challenging situation, and current guidelines for AP, pregnancy care, and surgery do not specifically address its management. This study investigated the safety and effectiveness of cholecystectomy and endoscopic retrograde cholangiopancreatography (ERCP) during pregnancy in AP.</p><p><strong>Methods: </strong>This international retrospective multicenter cohort study encompassed questions related to demographic information, clinical presentation, management strategies, timing of cholecystectomy, approaches to the procedure, complications, and outcomes. Continuous variables were summarized as medians with interquartile ranges, and categorical variables as frequencies and percentages. Group comparisons used Welch's t-test, Pearson's chi-squared, or Fisher's exact tests.</p><p><strong>Results: </strong>A total of 101 cases from 14 countries and 19 centers were enrolled. Cholecystectomy after mild AP during pregnancy had a lower rate of readmission due to recurrent AP or other gallstone-related complications compared with those who did not undergo surgery after a mild AP during pregnancy (0% vs. 24%; n = 0/17 vs. n = 12/49, p = 0.027). Cholecystectomy performed during pregnancy was associated with a low surgical complication rate, identical to that seen in postpartum procedures (12% vs. 10%; n = 2/17 vs. n = 3/30; p > 0.999). Preterm birth occurred in 7.1% (n = 1/14) of patients with cholecystectomy versus 11% (n = 5/45) without. Fetal loss after surgery occurred only in the first trimester (n = 3/17 vs. n = 1/49). No difference was seen in readmission (5%, n = 1/21 vs. 27%, n = 4/15; p = 0.138), fetal loss (5%, n = 1/21 vs. 27%, n = 4/15; p = 0.138) and preterm birth (6%, n = 1/17 vs. 8%, n = 1/12; p > 0.999) between the surgical and ERCP groups. The fetal loss (9.1%, n = 2/22 vs. 5.4%, n = 4/74; p = 0.618) and preterm birth rates (5.9%, n = 1/17 vs. 12%, n = 8/65; p = 0.677) did not significantly differ between patients with and without ERCP during pregnancy.</p><p><strong>Conclusion: </strong>Cholecystectomy is effective and safe in pregnant patients during the second or third trimester in cases of mild biliary pancreatitis. ERCP is safe in any trimester.</p>","PeriodicalId":23444,"journal":{"name":"United European Gastroenterology Journal","volume":" ","pages":""},"PeriodicalIF":6.7,"publicationDate":"2025-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145228299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Supplement: 33rd United European Gastroenterology Week 2025.","authors":"","doi":"10.1002/ueg2.70030","DOIUrl":"10.1002/ueg2.70030","url":null,"abstract":"","PeriodicalId":23444,"journal":{"name":"United European Gastroenterology Journal","volume":"13 Suppl 8 ","pages":"S4"},"PeriodicalIF":6.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12496560/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145233369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Supplement: 33rd United European Gastroenterology Week 2025.","authors":"","doi":"10.1002/ueg2.70032","DOIUrl":"10.1002/ueg2.70032","url":null,"abstract":"","PeriodicalId":23444,"journal":{"name":"United European Gastroenterology Journal","volume":"13 Suppl 8 ","pages":"S7-S188"},"PeriodicalIF":6.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12496558/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145233442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Supplement: 33rd United European Gastroenterology Week 2025.","authors":"","doi":"10.1002/ueg2.70038","DOIUrl":"10.1002/ueg2.70038","url":null,"abstract":"","PeriodicalId":23444,"journal":{"name":"United European Gastroenterology Journal","volume":"13 Suppl 8 ","pages":"S1539-S1558"},"PeriodicalIF":6.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12496567/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145233460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Supplement: 33rd United European Gastroenterology Week 2025.","authors":"","doi":"10.1002/ueg2.70035","DOIUrl":"10.1002/ueg2.70035","url":null,"abstract":"","PeriodicalId":23444,"journal":{"name":"United European Gastroenterology Journal","volume":"13 Suppl 8 ","pages":"S189-S802"},"PeriodicalIF":6.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12496564/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145233470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Supplement: 33rd United European Gastroenterology Week 2025.","authors":"","doi":"10.1002/ueg2.70029","DOIUrl":"10.1002/ueg2.70029","url":null,"abstract":"","PeriodicalId":23444,"journal":{"name":"United European Gastroenterology Journal","volume":"13 Suppl 8 ","pages":"S1-S3"},"PeriodicalIF":6.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12496557/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145233323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Supplement: 33rd United European Gastroenterology Week 2025.","authors":"","doi":"10.1002/ueg2.70036","DOIUrl":"10.1002/ueg2.70036","url":null,"abstract":"","PeriodicalId":23444,"journal":{"name":"United European Gastroenterology Journal","volume":"13 Suppl 8 ","pages":"S803-S1476"},"PeriodicalIF":6.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12496561/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145233505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Supplement: 33rd United European Gastroenterology Week 2025.","authors":"","doi":"10.1002/ueg2.70039","DOIUrl":"10.1002/ueg2.70039","url":null,"abstract":"","PeriodicalId":23444,"journal":{"name":"United European Gastroenterology Journal","volume":"13 Suppl 8 ","pages":"1559-1604"},"PeriodicalIF":6.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12496556/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145233476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Supplement: 33rd United European Gastroenterology Week 2025.","authors":"","doi":"10.1002/ueg2.70037","DOIUrl":"10.1002/ueg2.70037","url":null,"abstract":"","PeriodicalId":23444,"journal":{"name":"United European Gastroenterology Journal","volume":"13 Suppl 8 ","pages":"S1477-S1538"},"PeriodicalIF":6.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12496563/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145233494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}