Updates in Surgery最新文献_第6页

Pancreatic cancer and long survivors: a survey of Italian society of oncological surgery (SICO). 胰腺癌和长期存活者：意大利肿瘤外科学会（SICO）调查。

IF 2.4 3区医学

Updates in Surgery Pub Date : 2024-11-26 DOI: 10.1007/s13304-024-02039-3

Vincenzo D'Ambra, Carlo Ingaldi, Claudio Ricci, Laura Alberici, Giovanni Capretti, Elio Jovine, Caterina C Zingaretti, Roberto Salvia, Riccardo Casadei

{"title":"Pancreatic cancer and long survivors: a survey of Italian society of oncological surgery (SICO).","authors":"Vincenzo D'Ambra, Carlo Ingaldi, Claudio Ricci, Laura Alberici, Giovanni Capretti, Elio Jovine, Caterina C Zingaretti, Roberto Salvia, Riccardo Casadei","doi":"10.1007/s13304-024-02039-3","DOIUrl":"https://doi.org/10.1007/s13304-024-02039-3","url":null,"abstract":"Long-term survivors after pancreatic resection for PDAC are rare, constituting a specific subset of patients that remains poorly understood. The aim of this survey is to describe the current landscape related to survival in the Italian context and identify factors associated with long-term survival. An online survey, conducted by the Italian Society of Oncological Surgery (SICO) and endorsed by Italian Association of the Study of the Pancreas (AISP) and Italian Association of Hepatobiliary Pancreatic Surgery (AICEP), was distributed to surgeons in July 2023. The survey included 27 multiple-choice questions covering demographics, professional details, clinical practices, and long-term survival data. Responses were analyzed using descriptive statistics and multinomial logistic regression to identify factors related to long-term survival. The majority of surgeons (46.9%) considered LTS as \"alive at 5 years, regardless of disease-free status\". The percentage of patients alive at 5 years post-2013 was higher compared to pre-2013. Almost all centers (93.2%) held multidisciplinary discussions. Very high-volume centers (> 100 resections/year) in comparison to very low-volume (< 10 resections/year) showed better long-term survival rates. No difference in survival were observed between centers with low, medium, high, and very high volumes. In addition, centers with multidisciplinary approach showed better survival rates. Centers with more neoadjuvant chemotherapy rates, low-grade and low-stage tumors were also associated with improved survival outcomes. This survey has allowed to understand the Italian scenario regarding survival in patients undergoing surgery for PDAC.","PeriodicalId":23391,"journal":{"name":"Updates in Surgery","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142716628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Role of sleeve gastrectomy in improving metabolic syndrome: an overview. 袖带胃切除术在改善代谢综合征中的作用：综述。

IF 2.4 3区医学

Updates in Surgery Pub Date : 2024-11-25 DOI: 10.1007/s13304-024-02038-4

Adisa Poljo, Marko Kraljević, Ralph Peterli, Beat P Müller, Adrian T Billeter

{"title":"Role of sleeve gastrectomy in improving metabolic syndrome: an overview.","authors":"Adisa Poljo, Marko Kraljević, Ralph Peterli, Beat P Müller, Adrian T Billeter","doi":"10.1007/s13304-024-02038-4","DOIUrl":"https://doi.org/10.1007/s13304-024-02038-4","url":null,"abstract":"Metabolic syndrome (MetS) presents a global health challenge characterized by cardiometabolic risk factors like central obesity, elevated blood pressure, dyslipidemia, and high fasting glucose levels. Despite lifestyle interventions and medications, the increasing prevalence of MetS calls for effective treatments. Sleeve gastrectomy (SG) has emerged as a promising intervention. This review examines the role of SG in improving MetS outcomes, drawing from a PubMed/Medline literature search. It highlights SG's multifaceted metabolic effects, including hormonal changes and improved insulin sensitivity, contributing to improved metabolic outcomes. Additionally, SG leads to significant weight loss and effectively addresses comorbidities like hypertension, dyslipidemia, and type 2 diabetes mellitus (T2DM), with low rates of early morbidity and mortality. However, long-term studies indicate that Roux-en-Y gastric bypass (RYGB) provides more sustained weight loss and superior resolution of metabolic comorbidities, whereas SG is associated with fewer early complications and a lower risk of nutritional deficiencies. In conclusion, SG offers a valuable option for managing MetS, providing significant weight loss and comorbidity improvement. Nevertheless, potential long-term complications, such as gastroesophageal reflux disease (GERD) and suboptimal weight response, emphasize careful patient selection and monitoring.","PeriodicalId":23391,"journal":{"name":"Updates in Surgery","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142716640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Long-term outcomes of surgical management in post-intubation tracheal stenosis: a retrospective analysis of tracheal resection and reconstruction. 插管后气管狭窄手术治疗的长期效果：气管切除和重建的回顾性分析。

IF 2.4 3区医学

Updates in Surgery Pub Date : 2024-11-23 DOI: 10.1007/s13304-024-02040-w

Ahmet Ulusan, Ibrahim Emre Tunca, Bekir Elma, Maruf Sanli, Ahmet Feridun Isik

{"title":"Long-term outcomes of surgical management in post-intubation tracheal stenosis: a retrospective analysis of tracheal resection and reconstruction.","authors":"Ahmet Ulusan, Ibrahim Emre Tunca, Bekir Elma, Maruf Sanli, Ahmet Feridun Isik","doi":"10.1007/s13304-024-02040-w","DOIUrl":"https://doi.org/10.1007/s13304-024-02040-w","url":null,"abstract":"Post-intubation tracheal stenosis (PITS) is a serious complication of prolonged intubation, often requiring surgical intervention. This study aims to present the long-term outcomes of patients with PITS who underwent tracheal resection and reconstruction, as well as to discuss the efficacy of these surgical methods in comparison to stenting. This retrospective study included patients treated for PITS at our center between October 2005 and October 2022. Patients were divided into two groups: those who underwent tracheal resection and reconstruction (n = 29) and those treated with stenting (n = 47). The clinical characteristics, surgical techniques, complications, and long-term outcomes were recorded and analyzed. The mean age of the patients was 41.3 years, with 40.0% aged between 40 and 60 years. The mean intubation duration was 16.8 days. In the resection group, 22 of 29 patients (75.8%) showed no recurrence or complications during long-term follow-up. The overall success rate for surgical treatment was 93.1%, with a mortality rate of 6.8%. In the stenting group, successful stent removal was achieved in 9 of 47 cases, with a mean stent removal time of 26 months. Granulation tissue formation and restenosis were more frequently observed in stented patients compared to those who underwent surgery. Tracheal resection and end-to-end anastomosis remain the gold standard treatment for PITS, with a lower recurrence rate and fewer long-term complications compared to stenting. However, stenting may be a viable option for patients who are not suitable candidates for surgery. Careful preoperative evaluation and long-term follow-up are essential to optimize patient outcomes.","PeriodicalId":23391,"journal":{"name":"Updates in Surgery","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142695831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Anatomic lung resection after target therapy or immune checkpoint inhibitors treatment for initially unresectable advanced-staged non-small cell lung cancer: a case series. 对最初无法切除的晚期非小细胞肺癌进行靶向治疗或免疫检查点抑制剂治疗后进行肺解剖切除：病例系列。

IF 2.4 3区医学

Updates in Surgery Pub Date : 2024-11-21 DOI: 10.1007/s13304-024-02026-8

Giuseppe Mangiameli, Veronica Maria Giudici, Debora Brascia, Emanuele Voulaz, Umberto Cariboni, Luca Toschi, Marco Alloisio, Giuseppe Marulli

{"title":"Anatomic lung resection after target therapy or immune checkpoint inhibitors treatment for initially unresectable advanced-staged non-small cell lung cancer: a case series.","authors":"Giuseppe Mangiameli, Veronica Maria Giudici, Debora Brascia, Emanuele Voulaz, Umberto Cariboni, Luca Toschi, Marco Alloisio, Giuseppe Marulli","doi":"10.1007/s13304-024-02026-8","DOIUrl":"https://doi.org/10.1007/s13304-024-02026-8","url":null,"abstract":"Recently targeted therapy and immunotherapy have been demonstrated to improve survival in non-operable, non-small cell lung cancer (NSCLC) patients. The results of salvage lung resection in patients with initially unresectable advanced NSCLC after immune checkpoint inhibitor (ICI) or Target Therapy (TT) treatment remain limited and unclear. We aimed to define the outcomes of patients undergoing salvage surgery in a real-life setting. A case series study evaluation of clinical data from patients submitted to salvage surgery was performed. Patients included in the study were judged inoperable, according to a multidisciplinary tumor board decision, before being submitted to ICI or TKI treatment. Data were analyzed using Chi-squared, Fisher's and Wilcoxon rank-sum tests, where appropriate. Eighteen patients were enrolled. Sixty-seven per cent were Stage IIIB and IV. Fifty per cent of cases received TKI treatment, the remaining patients received ICI alone or with chemo- and/or radiotherapy. Twenty-two per cent of cases were scheduled and successfully performed by minimal invasive approach without needing for conversion. Overall, 5 patients (28%) developed postoperative complications, the 90-day mortality was zero. The major pathologic response rate was 27.7%. The median OS was months 24.7 months with sixteen of 18 patients alive (89%) at last follow-up. No difference was recorded between TT and ICI group in term of complication rate, length of hospital stay and survival. In our experience, salvage surgery after ICI or TT have reasonable post-operative and long-term outcomes. Salvage surgery could be proposed in selected patients after a careful multidisciplinary evaluation.","PeriodicalId":23391,"journal":{"name":"Updates in Surgery","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142689040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Differences in the epidemiology and survival of patients with colorectal cancer between China and the United States: a large cross-sectional study. 中国和美国结直肠癌患者的流行病学和生存率差异：一项大型横断面研究。

IF 2.4 3区医学

Updates in Surgery Pub Date : 2024-11-20 DOI: 10.1007/s13304-024-02024-w

Yu Shen, Hongyu Cai, Dan Zhou, Jinliang Gao, Tinghan Yang, Haining Chen, Mingtian Wei, Ziqiang Wang

{"title":"Differences in the epidemiology and survival of patients with colorectal cancer between China and the United States: a large cross-sectional study.","authors":"Yu Shen, Hongyu Cai, Dan Zhou, Jinliang Gao, Tinghan Yang, Haining Chen, Mingtian Wei, Ziqiang Wang","doi":"10.1007/s13304-024-02024-w","DOIUrl":"https://doi.org/10.1007/s13304-024-02024-w","url":null,"abstract":"Studying the epidemiological and management characteristics of colorectal cancer (CRC) between China and the US has important implications. The present cross-sectional study included patients from SEER and Southwest China Colorectal (SCC) databases. Incidence, treatment and survival information were compared between two countries. 86859 patients in the SEER database and 5838 patients in the SCC database were included. The estimated incidence of CRC in the US was greater than that in China from 2006 to 2019. The most common tumor sites of CRC patients in China were the RSC (66.5%), RCC (20.2%) and LCC (13.3%), while those in the US were the RCC (44.4%), RSC (29.8%) and LCC (25.8%). Chinese CRC patients were more likely to be male (58.9% vs 52.4%, p < 0.001), have a greater stage II CRC rate (49.8% vs 27.8%, p < 0.001), younger age at diagnosis (median 64 vs 66 years, p < 0.001). Radical surgery rates were lower in Chinese RCC (92.3% vs 93.9%, p < 0.001) and LCC (88.9% vs 92.0%, p < 0.001) patients. The adjuvant therapy rates were lower in Chinese CRC patients. The 5-year overall survival rates were 71.8% and 78.2% for Chinese and US CRC patients, respectively (p < 0.001). China is undergoing an increasing incidence of CRC. The treatment and mortality of CRC differ in China and US populations. China had a lower adjuvant therapy rate and a lower 5-year OS rate compared with the US.","PeriodicalId":23391,"journal":{"name":"Updates in Surgery","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142677001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mid-transversal hepatectomy: breaking new ground in parenchymal sparing hepatectomies. 中横断肝切除术：开辟肝实质切除术的新天地。

IF 2.4 3区医学

Updates in Surgery Pub Date : 2024-11-15 DOI: 10.1007/s13304-024-02015-x

Guido Costa, Guido Torzilli, Virginia Laurenti, Fabio Procopio

引用次数: 0

Liver transplantation: Do not abandon T-tube drainage-a multicentric retrospective study of the ARCHET research group. 肝移植：不要放弃 T 管引流--ARCHET 研究小组的多中心回顾性研究。

IF 2.4 3区医学

Updates in Surgery Pub Date : 2024-11-14 DOI: 10.1007/s13304-024-02008-w

Laurence Chiche, Arthur Marichez, Michel Rayar, Agathe Simon, Kayvan Mohkam, Fabrice Muscari, Karim Boudjema, Jean-Yves Mabrut, Jean-Philippe Adam, Christophe Laurent

{"title":"Liver transplantation: Do not abandon T-tube drainage-a multicentric retrospective study of the ARCHET research group.","authors":"Laurence Chiche, Arthur Marichez, Michel Rayar, Agathe Simon, Kayvan Mohkam, Fabrice Muscari, Karim Boudjema, Jean-Yves Mabrut, Jean-Philippe Adam, Christophe Laurent","doi":"10.1007/s13304-024-02008-w","DOIUrl":"https://doi.org/10.1007/s13304-024-02008-w","url":null,"abstract":"Biliary complications remain a real issue in liver transplantation (LT). Despite meta-analyses, the anastomosis technique, especially the use of biliary drain as T-Tube drain (TT) or transcystic drain, remains controversial. This study conducted by the ARCHET research group examine the incidence and types of biliary complications (BC) after LT according to the presence or absence of a biliary drain. 1485 patients with LT surgery between 2009 to 2015 in 4 LT centers were included, divided into 3 groups: no drain (ND n = 442), transcystic drain (TCD, n = 169) and TT(n = 874).The T-Tube group includes 3 techniques: transanastomotic, subanastomotic and tunneled retroperitoneal. Fistula and biliary stricture (AS) rates were studied. The risk factors of BC were investigated by multivariate analysis. The BC rate was lower in the TT group (17% TT, 25% TCD, 31% ND, p < 0.05), the complication rate Dindo-Clavien grade ≥ III is higher in the ND group (24% vs. 10% TT p < 0.05). Arterial complication has been found as a risk factor of BC with the multivariate analysis (p < 0.01, OR 1.86 [1.20-2.84]). In addition, the TT decreased by 5 the risk of AS (p < 0.05, OR 0.19 [0.12-0.28]). The fistula rate does not differ regardless of the reconstruction mode. In this study, biliary drain decreases the rate of BC. The findings confirmed the role of T-tube insertion in prevention of AS regardless of the way it is set up.","PeriodicalId":23391,"journal":{"name":"Updates in Surgery","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142629019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Matching the opposites: liver transplantation from a situs viscerum inversus totalis donor. 对立面的匹配：完全性粘连的肝脏移植。

IF 2.4 3区医学

Updates in Surgery Pub Date : 2024-11-13 DOI: 10.1007/s13304-024-01968-3

Cristiano Guidetti, Roberta Odorizzi, Barbara Catellani, Philip Muller, Paolo Magistri, Gian Piero Guerrini, Stefano Di Sandro, Fabrizio Di Benedetto

{"title":"Matching the opposites: liver transplantation from a situs viscerum inversus totalis donor.","authors":"Cristiano Guidetti, Roberta Odorizzi, Barbara Catellani, Philip Muller, Paolo Magistri, Gian Piero Guerrini, Stefano Di Sandro, Fabrizio Di Benedetto","doi":"10.1007/s13304-024-01968-3","DOIUrl":"https://doi.org/10.1007/s13304-024-01968-3","url":null,"abstract":"Situs viscerum inversus totalis (SIT) is a rare congenital anomaly. Deceased donors with this condition are often declined because of the technical issues in both the organ's procurement and its transplant. Only eight cases of deceased donor organs with SIT were reported to be used for liver transplantation (LT). We herein present a case of LT using a graft from an SIT donor: a modified retroversus piggyback technique was used. A 15 year-old female was referred to our institution as a potential donor. An SIT condition was discovered during standard donor evaluation together with the presence of a complex triple arterial pedicle. Procurement operative time was 125 min, from skin incision to cross-clamp. Liver extraction occurred 32 min after cold flush. The recipient was a 56 year-old male affected by recurrent hepatocellular carcinoma (HCC) on hepatitis C related liver cirrhosis. Position and orientation trials of the graft were made and it was decided to implant it with the retroversus technique. Direct duct-to-duct biliary reconstruction was achieved. The postoperative course was uneventful. To our knowledge, this is the first implant with retroversus technique combined to direct biliary reconstruction and the first repetition of that technique. Cases like this highlight how technical complexity can be overcome leading to successful management of difficult scenarios in a safe manner.","PeriodicalId":23391,"journal":{"name":"Updates in Surgery","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142629024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Critical view of safety approach vs. infundibular technique in laparoscopic cholecystectomy, which one is safer? A systematic review and meta-analysis. 腹腔镜胆囊切除术中安全入路与腹股沟技术的批判性观点，哪一种更安全？系统回顾和荟萃分析。

IF 2.4 3区医学

Updates in Surgery Pub Date : 2024-11-11 DOI: 10.1007/s13304-024-02029-5

Bahaa I Aburayya, Ahmad K Al-Hayk, Ahmad A Toubasi, Abubaker Ali, Awni D Shahait

{"title":"Critical view of safety approach vs. infundibular technique in laparoscopic cholecystectomy, which one is safer? A systematic review and meta-analysis.","authors":"Bahaa I Aburayya, Ahmad K Al-Hayk, Ahmad A Toubasi, Abubaker Ali, Awni D Shahait","doi":"10.1007/s13304-024-02029-5","DOIUrl":"https://doi.org/10.1007/s13304-024-02029-5","url":null,"abstract":"Laparoscopic cholecystectomy (LC) remains the gold standard procedure for the management of benign gallbladder disease. Recognizing the need to mitigate complications, mainly bile duct injury (BDI), various techniques for ductal identification during LC have emerged, including the \"Critical View of Safety\" (CVS) and the infundibular technique (IT). In this systematic review and meta-analysis, we assess and compare the outcomes of both techniques, with a primary focus on evaluating their impact on BDIs. A comprehensive search was conducted using PubMed and Scopus databases. The search focused on the surgical technique, incidences of minor and major BDIs, operative time, conversion rate, and length of stay, among patients undergoing LC for benign gallbladder disease. Our initial search retrieved 264 studies. After screening the unique studies against our predefined inclusion/exclusion criteria, only five met our criteria and were included. Additionally, a manual search identified eight more relevant studies, bringing the total number of included studies to 13. The total number of included patients was 4,837. Approximately two-thirds underwent LC using the CVS approach (61.1%), and 66.3% were female, with a mean age of 44.4 ± 11.2 years. The CVS approach was associated with a significant reduction in overall BDIs (RR = 0.36; 95% CI 0.18-0.71) and major BDIs (RR = 0.28; 95% CI 0.13-0.63). However, there were no significant differences in terms of minor BDIs, operative time, conversion rates, or length of stay. Our study demonstrated the superiority of the CVS approach in terms of reducing the incidence of overall and major BDIs compared to IT. However, our study revealed no other significant differences between the two techniques. Further research, including multicentric randomized controlled trials, will be necessary to further evaluate the efficacy of these techniques.","PeriodicalId":23391,"journal":{"name":"Updates in Surgery","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142628880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of bariatric surgery on hyperuricemia and gout: a systematic review of the literature. 减肥手术对高尿酸血症和痛风的影响：文献系统回顾。

IF 2.4 3区医学

Updates in Surgery Pub Date : 2024-11-09 DOI: 10.1007/s13304-024-02028-6

Emanuele Soricelli, Giovanni Quartararo, Luca Leuratti, Luigi Schiavo, Antonio Iannelli, Enrico Facchiano

{"title":"Effects of bariatric surgery on hyperuricemia and gout: a systematic review of the literature.","authors":"Emanuele Soricelli, Giovanni Quartararo, Luca Leuratti, Luigi Schiavo, Antonio Iannelli, Enrico Facchiano","doi":"10.1007/s13304-024-02028-6","DOIUrl":"https://doi.org/10.1007/s13304-024-02028-6","url":null,"abstract":"Gout is the most common form of inflammatory arthritis, and it is due to the deposition of monosodium urate crystals in the articular and extra-articular tissues. Body mass index is strongly correlated with elevated serum uric acid levels and gout is often associated with obesity and metabolic syndrome. Recommended nonpharmacological treatments for hyperuricemia and gout include dietary modifications and weight loss. Many studies have demonstrated that weight loss could reduce serum urate in patients with obesity and it is a commonly recommended treatment for gout. Bariatric surgery-induced weight loss exerts beneficial effects on hyperuricemia and gout, even if a possible raise of gout flares can be observed in patients with hyperuricemia early after surgery. The aim of this review is to systematically analyze all the studies published so far reporting a link between hyperuricemia and/or gout and bariatric surgery to obtain reliable figures on the incidence of this disease and describe the mechanisms underlying this association. Eleven studies accounting for 11,256 patients were included in the review. Mean preoperative prevalence of gout was 4.1%, while the preoperative prevalence of hyperuricemia ranged from 30.6% to 58%. After a mean follow-up of 8.5 months, postoperative prevalence of gout significantly decreased to 2.9% (p < .007). The incidence of gout flares after bariatric surgery was higher in the early postoperative phase and progressively decreased over time. Similarly, serum uric acid concentrations showed an increase within the first postoperative month, which was followed by a progressive decrease below the preoperative value.","PeriodicalId":23391,"journal":{"name":"Updates in Surgery","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142628907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0