Translational Research in Oral Oncology最新文献

Patients with oral submucous fibrosis who visit dental hospitals have nonspecific chief complaints 访问牙科医院的口腔黏膜下纤维化患者有非特异性主诉

Translational Research in Oral Oncology Pub Date : 2019-06-20 DOI: 10.1177/2057178X19858453

A. Gadbail, Ravi Dande, S. Sarode, S. Gondivkar, Lalita Belekar, Mugdha P. Mankar‐Gadbail, G. Sarode, S. Patil, M. Yuwanati

{"title":"Patients with oral submucous fibrosis who visit dental hospitals have nonspecific chief complaints","authors":"A. Gadbail, Ravi Dande, S. Sarode, S. Gondivkar, Lalita Belekar, Mugdha P. Mankar‐Gadbail, G. Sarode, S. Patil, M. Yuwanati","doi":"10.1177/2057178X19858453","DOIUrl":"https://doi.org/10.1177/2057178X19858453","url":null,"abstract":"Background: The first consultation with a health-care professional is crucial to make the correct diagnosis particularly with respect to narrating the symptoms encountered by the patient. Yet, currently, no information is available concerning the primary symptoms documented by patients with oral submucous fibrosis (OSF). Materials and Methods: A total of 158 OSF patients visiting outdoor patient departments (OSF-OPDs) and 104 pan shop customers (PSCs) were investigated. OSF-OPD cases and relevant PSCs cases were investigated to discover the chief complaints (CCs) leading to dental visits. Detailed demographic data, patient histories concerning relevant habits (with duration), and socioeconomic status were recorded. OSF cases were graded based on the degree of mouth opening. Results: Out of 158 OSF-OPD patients, only 43 (26.58%) reported relevant disease symptoms of OSF: in stage III, 28.57%, or stage IV, 38.09%. One hundred and sixteen patients (73.41%) reported CCs unrelated to OSF, and all of these cases were diagnosed with an early stage of OSF (stage I: 47.05% and stage II: 22.5%). Out of the total 104 PSCs, 66 PSCs have had prior dental consultations, but only five (4.80%) individuals had visited a health-care professional due to OSF-related CCs. Conclusion: A significant number of CCs made by OSF patients were unrelated to their disease signs and symptoms. There is a lack of awareness of OSF symptoms by pan chewers, thus hindering early detection.","PeriodicalId":233876,"journal":{"name":"Translational Research in Oral Oncology","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116803436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

A revisit at 16 years for individuals from peri-urban New Delhi for tobacco use and associated oral lesions 对来自新德里城郊的吸烟和相关口腔病变的16岁人群进行重新调查

Translational Research in Oral Oncology Pub Date : 2019-01-08 DOI: 10.1177/2057178X18818661

R. Mehrotra, S. Nethan, Priyanka Ravi, S. Grover, Shashi Sharma, G. Rath, J. Kaur, R. Ralhan, A. Srivastava

{"title":"A revisit at 16 years for individuals from peri-urban New Delhi for tobacco use and associated oral lesions","authors":"R. Mehrotra, S. Nethan, Priyanka Ravi, S. Grover, Shashi Sharma, G. Rath, J. Kaur, R. Ralhan, A. Srivastava","doi":"10.1177/2057178X18818661","DOIUrl":"https://doi.org/10.1177/2057178X18818661","url":null,"abstract":"Objectives: India has a high incidence of oral cancer due to multifarious tobacco use. The objective of this study was to assess the status of tobacco-related oral lesions over 16 years, in a screen-detected population. Methods: This cross-sectional study involved home visits of 2000 Delhi residents, previously screened for oral potentially malignant disorders/oral cancer and counseled for tobacco cessation. Their basic demographics and tobacco/alcohol history were noted followed by oral visual examination for any related mucosal abnormalities. The data thus obtained were statistically analyzed. Results: Two hundred and sixty-five individuals (13.2%) could be traced after 16 years. The status of oral lesions varied across the participants, mainly in terms of their location, type, number, and/or presence/absence; no oral malignancies were noted. Most individuals had either a decreased use (34%, p < 0.001) or had quit tobacco (25.7%, p < 0.001); 8.3% individuals from the former and 5.7% from the latter group showed complete lesion(s) regression. The overall change in the tobacco use and oral lesions showed a highly significant positive association (p < 0.05). Conclusion: A direct relationship exists between tobacco use and oral lesions. Repeated, tobacco cessation counseling provided by health-care professionals is effective. Oral screening of high-risk individuals, along with tobacco cessation, is thus essential.","PeriodicalId":233876,"journal":{"name":"Translational Research in Oral Oncology","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126694307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Role of Candida infection in the malignant transformation of oral leukoplakia: A systematic review of observational studies 念珠菌感染在口腔白斑恶性转化中的作用:一项观察性研究的系统综述

Translational Research in Oral Oncology Pub Date : 2019-01-01 DOI: 10.1177/2057178x19828229

Khilan Shukla, Ida Vun, I. Lov, George Laparidis, C. McCamley, A. Ariyawardana

引用次数: 21

Top cited articles on ameloblastoma: A bibliometric analysis 关于成釉细胞瘤的高被引文章:文献计量学分析

Translational Research in Oral Oncology Pub Date : 2019-01-01 DOI: 10.1177/2057178X18821018

S. Gondivkar, S. Sarode, A. Gadbail, Rima S. Gondivkar, G. Sarode, Nilookumari Choudhary, S. Patil

{"title":"Top cited articles on ameloblastoma: A bibliometric analysis","authors":"S. Gondivkar, S. Sarode, A. Gadbail, Rima S. Gondivkar, G. Sarode, Nilookumari Choudhary, S. Patil","doi":"10.1177/2057178X18821018","DOIUrl":"https://doi.org/10.1177/2057178X18821018","url":null,"abstract":"Objectives: The purpose of this study was to review and evaluate the characteristics of 100 most cited articles on ameloblastoma (AB). Materials and Methods: A comprehensive list of citation classics in AB was generated by searching the Scopus database without year or language restrictions. The top 100 articles were retrieved after reading abstracts or full texts. The following study variables were evaluated: number of citations, citation density, journal name, impact factor, category and quartile of journals, publication year, authors with their affiliations, and article type. Results: The citation number ranged from 76 to 367, with a mean of 122.78 citations per article. The one hundred top cited articles were distributed in 41 journals with Cancer having the highest number of articles (n = 16). There was a dominance of authors form United States (42 articles). The articles were published from 1955 to 2014, and eight authors published more than three papers. There were 57 research articles and 43 review articles. Conclusions: This first citation analysis provide a detailed list of the most influential articles on AB to help recognize the quality of the works, discoveries, and the trends steering the study of AB.","PeriodicalId":233876,"journal":{"name":"Translational Research in Oral Oncology","volume":"79 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133007319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Expression and clinical significance of the receptors of the EGF family in oral squamous cell carcinomas EGF家族受体在口腔鳞状细胞癌中的表达及临床意义

Translational Research in Oral Oncology Pub Date : 2019-01-01 DOI: 10.1177/2057178X19836532

U. Dissanayake

{"title":"Expression and clinical significance of the receptors of the EGF family in oral squamous cell carcinomas","authors":"U. Dissanayake","doi":"10.1177/2057178X19836532","DOIUrl":"https://doi.org/10.1177/2057178X19836532","url":null,"abstract":"Objective: To examine the immunohistochemical expression of four members of the type 1 growth factor receptor family in oral squamous cell carcinomas (OSCCs) and to correlate with clinical outcomes. Materials and methods: Sixty OSCCs from a patient cohort in Sri Lanka were included in the study. Five sections from each carcinoma were immunostained with antibodies to epidermal growth factor receptor (EGFR)/c-erbB-1, c-erbB-2/HER-2/neu, c-erbB-3/HER-3 and c-erbB-4/HER-4. Two clones were used to stain for c-erbB-2/HER-2/neu. Semiquantitative analysis of immunoreactivity was carried out by scoring the intensity of expression and proportions of positively stained cells. A logistic regression analysis was performed to examine positive expression against overall survival. Results: There was heterogenous expression of the four receptors, positivity ranging from 26% to 60%. Co-expression of all four markers was observed only in 1–3% of the tumours. Both membranous and cytoplasmic expressions were observed, EGFR showing predominantly membranous expression and c-erbB-2 showing only cytoplasmic staining. In logistic regression analysis, none of the growth factor receptors were significantly predictive of overall survival. Conclusion: Type 1 growth factor receptors are highly expressed in oral carcinomas, EGFR being the predominant marker.","PeriodicalId":233876,"journal":{"name":"Translational Research in Oral Oncology","volume":"96 Suppl C 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123791490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Perspectives on areca nut with some global implications: Symposium report 槟榔果与一些全球影响的观点:研讨会报告

Translational Research in Oral Oncology Pub Date : 2018-11-30 DOI: 10.1177/2057178X18814068

Prakash C. Gupta, C. Ray, R. Papke, I. Stepanov, S. Khariwala, P. Chaturvedi, H. Gupte, M. Pednekar

{"title":"Perspectives on areca nut with some global implications: Symposium report","authors":"Prakash C. Gupta, C. Ray, R. Papke, I. Stepanov, S. Khariwala, P. Chaturvedi, H. Gupte, M. Pednekar","doi":"10.1177/2057178X18814068","DOIUrl":"https://doi.org/10.1177/2057178X18814068","url":null,"abstract":"Areca nut and products made from the nut, evaluated by the International Agency for Research on Cancer as carcinogenic to humans since 2004, are being increasingly used in India and South East Asia and exported to many countries. There is thus an urgent need to identify best control policies and research gaps. On 1 February 2018, a group of experts shared their latest knowledge and perspectives on areca nut at Healis-Seksaria Institute for Public Health in Navi Mumbai, Maharashtra, India. By itself, areca nut has been implicated in oral and oesophageal cancer. Areca nut users are also at high risk of oral submucous fibrosis, a debilitating and potentially malignant condition. Users may also suffer adverse health outcomes due to smokeless tobacco, commonly mixed with areca nut. The use of areca nut commonly begins in childhood and often proceeds to use with tobacco. Gutka, a widely consumed, industrially made areca nut product containing tobacco, has been banned in all states and union territories of India, but it is still widely available. Areca nuts contain arecoline, an alkaloid that stimulates various brain receptors, promoting physical dependence. Areca nut alkaloids have also been implicated in carcinogenesis. Other chemicals, introduced during cultivation and processing of areca nuts, contribute to oral submucous fibrosis and cancer. The wide variety of products, different storage conditions and lack of regulation can lead to significant variation in the content of toxicants, carcinogens and alkaloids, making the psychological and physical dependence issues even more challenging. Regulation of product contents is needed as a part of control measures to supplement product bans.","PeriodicalId":233876,"journal":{"name":"Translational Research in Oral Oncology","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115028600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 27

Abrasive cytohistology of squamous epithelial lesions 鳞状上皮病变的磨蚀性细胞组织学

Translational Research in Oral Oncology Pub Date : 2018-10-31 DOI: 10.1177/2057178X18808671

A. Burkhardt, S. Schwarz-Furlan

{"title":"Abrasive cytohistology of squamous epithelial lesions","authors":"A. Burkhardt, S. Schwarz-Furlan","doi":"10.1177/2057178X18808671","DOIUrl":"https://doi.org/10.1177/2057178X18808671","url":null,"abstract":"Objective: To describe a method to retrieve cellular and tissue elements of oral squamous epithelium obtained by abrasive methods and to conduct investigations by cytohistology. Method: We developed a special gelatine pocket suitable for paraffin embedding of sparse material obtained from brush biopsies (BBs). This was subjected to combined evaluation of a cytological (smear) and histological examination of the ‘tissue sections’ – referred as cytohistology. Four diagnostic categories were applied for evaluation. Other special diagnostic methods were also applied in addition to recording dysplasia. Results: A total of 51, 755 BBs from suspicious lesions of the oral mucosa (mostly oral potentially malignant disorders – OPMD) were evaluated for the presence of carcinoma or dysplasia; in all, 1.7% were positive, 78.2% were negative for any epithelial atypia, 16.8% atypical and 3.3% inadequate. All BBs also had cytohistological evaluation. A ‘positive’ diagnosis by cytohistology was a reliable indicator of dysplasia or carcinoma, requiring further incisional/excisional biopsy. In the ‘atypical’ category, a variety of lesions were found, about half being dysplasia or carcinoma. This category challenges the clinician for further clinical, therapeutic and/or excisional examination. In ‘negative’ cases with persistence of the lesion, a re-examination in 1-year sequence is recommended. Conclusion: Cytohistology of material derived by abrasive methods allows earlier detection of dysplasia/carcinoma. A number of additional oncological and non-oncological findings make this method a valuable non-invasive diagnostic procedure for oral mucosal lesions.","PeriodicalId":233876,"journal":{"name":"Translational Research in Oral Oncology","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124683367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Testican 1 (SPOCK1) and protein tyrosine phosphatase, receptor type S (PTPRS) show significant increase in saliva of tobacco users with oral cancer 口腔癌烟草使用者唾液中睾丸素1 (SPOCK1)和蛋白酪氨酸磷酸酶受体S (PTPRS)显著升高

Translational Research in Oral Oncology Pub Date : 2018-09-25 DOI: 10.1177/2057178X18800534

Vishalakshi Nanjappa, R. Raja, A. Radhakrishnan, Ankit P Jain, K. Datta, Vinuth N. Puttamallesh, H. Solanki, S. Chavan, Arun H. Patil, S. Renuse, Anu Jain, D. Mathew, Reetu Thakur, Rafael Guerrero-Preston, B. Nair, S. Routray, N. Mohanty, K. L. Gowda, Ritesh Jadav, S. Ghosal, R. Kumar, C. Ramesha, Vijay C. Raghu, P. Mathur, T. K. Prasad, J. Califano, D. Sidransky, A. Pal, M. Ganesh, J. Ray, A. Pandey, H. Gowda, Aditi Chatterjee

{"title":"Testican 1 (SPOCK1) and protein tyrosine phosphatase, receptor type S (PTPRS) show significant increase in saliva of tobacco users with oral cancer","authors":"Vishalakshi Nanjappa, R. Raja, A. Radhakrishnan, Ankit P Jain, K. Datta, Vinuth N. Puttamallesh, H. Solanki, S. Chavan, Arun H. Patil, S. Renuse, Anu Jain, D. Mathew, Reetu Thakur, Rafael Guerrero-Preston, B. Nair, S. Routray, N. Mohanty, K. L. Gowda, Ritesh Jadav, S. Ghosal, R. Kumar, C. Ramesha, Vijay C. Raghu, P. Mathur, T. K. Prasad, J. Califano, D. Sidransky, A. Pal, M. Ganesh, J. Ray, A. Pandey, H. Gowda, Aditi Chatterjee","doi":"10.1177/2057178X18800534","DOIUrl":"https://doi.org/10.1177/2057178X18800534","url":null,"abstract":"Objectives: To identify potential candidate proteins which are secretory in nature and present at a higher abundance in oral cancer patients with tobacco habits. Methods: Conditioned media of tobacco-treated and -untreated non-neoplastic oral keratinocytes were analyzed using iTRAQ-based mass spectrometry. Hypersecreted proteins; SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1 (SPOCK1); prosaposin (PSAP); and protein tyrosine phosphatase, receptor type S (PTPRS) were validated by enzyme-linked immunosorbent assay (ELISA) using saliva samples from oral cancer patients who are tobacco users. Results: Proteomic analysis of tobacco-treated and -untreated cells led to the identification of 2873 proteins. Among these, 378 proteins showed high abundance and 253 proteins showed low abundance (2-fold cutoff) in conditioned-media of tobacco-treated cells. ELISA-based validation showed significantly higher levels of SPOCK1, PSAP, and PTPRS in oral cancer patients with tobacco chewing habits compared to healthy controls. However, PSAP showed low specificity compared to SPOCK1 and PTPRS. Conclusions: This study indicates significantly increased levels of SPOCK1, PSAP, and PTPRS in saliva of oral cancer patients with tobacco habits. These protein biomarkers might be useful to identify tobacco users with high risk of developing oral cancers.","PeriodicalId":233876,"journal":{"name":"Translational Research in Oral Oncology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124114829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Evidence for chronic mechanical irritation as a causative factor in oral cancer: application of Bradford Hill criteria 慢性机械刺激作为口腔癌致病因素的证据:Bradford Hill标准的应用

Translational Research in Oral Oncology Pub Date : 2018-08-14 DOI: 10.1177/2057178X18791034

E. Piemonte, J. Lazos

{"title":"Evidence for chronic mechanical irritation as a causative factor in oral cancer: application of Bradford Hill criteria","authors":"E. Piemonte, J. Lazos","doi":"10.1177/2057178X18791034","DOIUrl":"https://doi.org/10.1177/2057178X18791034","url":null,"abstract":"Chronic mechanical irritation (CMI) of the oral mucosa has been proposed as a risk factor for oral cancer (OC), but the available evidence is limited and controversial. One of the main limitations is the lack of proper criteria to define and classify CMI. The objective of this narrative review is to apply the Bradford Hill causality criteria to assess such an association based on the published literature. The level of evidence is not conclusive, mainly due to methodological shortcomings. Hence, to systematize future CMI research, we recommend the following items should be included: a clear definition for CMI, ascertaining any temporal association, recording all types of CMI: dental, prosthetic, and functional. Finally, it is important to emphasize that studies dealing with risk factors for OC should not only be restricted to established factors such as tobacco, alcohol, and areca nut consumption but should also consider other factors including the patient’s dental condition. In this regard, CMI, tooth loss, periodontal disease, and many others could be included. The causality criteria set out by Bradford Hill could be used for studying different controversial risk factors for OC.","PeriodicalId":233876,"journal":{"name":"Translational Research in Oral Oncology","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129987563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

Human papillomavirus DNA prevalence and type distribution in oral squamous cell carcinoma in Ghana 人乳头瘤病毒DNA在加纳口腔鳞状细胞癌中的流行和类型分布

Translational Research in Oral Oncology Pub Date : 2018-07-09 DOI: 10.1177/2057178X18787127

R. Dawson, N. Nartey, F. Kwamin, E. A. Nyako, R. Asmah, Harriet Blankson, Samuel D. Mensah, T. Ndanu, N. Johnson

{"title":"Human papillomavirus DNA prevalence and type distribution in oral squamous cell carcinoma in Ghana","authors":"R. Dawson, N. Nartey, F. Kwamin, E. A. Nyako, R. Asmah, Harriet Blankson, Samuel D. Mensah, T. Ndanu, N. Johnson","doi":"10.1177/2057178X18787127","DOIUrl":"https://doi.org/10.1177/2057178X18787127","url":null,"abstract":"Objective: To determine the prevalence of human papillomavirus (HPV) DNA in oral squamous cell carcinoma (OSCC). Methods: A total of 88 OSCC specimens collected between 2006 and 2013 were available for the study. DNA was extracted using formalin-fixed, paraffin-embedded specimens and analysed for the presence of 18 HPV genotypes using a nested polymerase chain reaction using consensus forward primer (GP-E6-3F) and two consensus back primers (GP-E7-5B and GP-E7-6B). Plasmid DNA of HPV 16 and 18 was used as positive controls. Results: HPV DNA was detected in 3 of the 88 samples, a prevalence of 3.4%. Genotypes detected were 16, 18 and 52. Conclusion: The overall prevalence of HPV DNA was 3.4%. Only high-risk genotypes were detected. This low prevalence of high-risk types of HPV suggests that the HPV virus may not have a significant role in the development of oral cancers in Ghana, unlike higher rates described elsewhere in the world, especially in Western countries. Surveillance of future prevalence of HPV and attention to other major risk factors is warranted.","PeriodicalId":233876,"journal":{"name":"Translational Research in Oral Oncology","volume":"60 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116584405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1