Turkish Journal of SurgeryPub Date : 2023-03-20eCollection Date: 2023-12-01DOI: 10.47717/turkjsurg.2023.230401
Barış Zülfikaroğlu
{"title":"In memory of Prof. Dr. Ahmet Çınar Yastı.","authors":"Barış Zülfikaroğlu","doi":"10.47717/turkjsurg.2023.230401","DOIUrl":"https://doi.org/10.47717/turkjsurg.2023.230401","url":null,"abstract":"","PeriodicalId":23374,"journal":{"name":"Turkish Journal of Surgery","volume":"39 4","pages":"ix"},"PeriodicalIF":0.6,"publicationDate":"2023-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11057930/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140865906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Experience of kidney transplantation to a patient with Bernard Soulier syndrome: A case report.","authors":"Cihan Karataş, Başak Akyollu, Emre Arpalı, Berna Yelken, Aydın Türkmen, Burak Koçak","doi":"10.47717/turkjsurg.2022.4567","DOIUrl":"https://doi.org/10.47717/turkjsurg.2022.4567","url":null,"abstract":"<p><p>Renal transplantation could be a challenging operation in patients with haemorrhagic diathesis, with predictable difficulties or even with unpredictable hurdles. Bernard Soulier Syndrome (BSS) is one of the ethiologies of the thrombocytopenia and it is a rare hereditary disease associated with defects of the platelet glycoprotein complex glycoprotein Ib/V/IX and characterized by large platelets, thrombocytopenia, and severe bleeding symptoms. Here, we present a challenging renal transplantation in BSS.</p>","PeriodicalId":23374,"journal":{"name":"Turkish Journal of Surgery","volume":"39 1","pages":"86-88"},"PeriodicalIF":0.6,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10234715/pdf/TJS-39-086.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9587962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yusuf Emre Aytin, İbrahim Ethem Cakcak, Tamer Sağıroğlu
{"title":"The evaluation of morbidity in gastrointestinal tumor patients underwent cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (HIPEC).","authors":"Yusuf Emre Aytin, İbrahim Ethem Cakcak, Tamer Sağıroğlu","doi":"10.47717/turkjsurg.2023.5706","DOIUrl":"https://doi.org/10.47717/turkjsurg.2023.5706","url":null,"abstract":"<p><strong>Objectives: </strong>In this study, we aimed to determine the postoperative morbidity rate and identify demographic, clinical, and treatment-related variables that may be potential risk factors for morbidity in gastrointestinal tumor patients undergoing hyperthermic intraperitoneal chemotherapy (HIPEC) with or without cytoreductive surgery (CRS).</p><p><strong>Material and methods: </strong>In this retrospective study, 60 patients who had undergone HIPEC due to gastrointestinal tumor between October 2017 and December 2019 were included. Systemic toxicities were graded and evaluated according to the National Cancer Institute (NCI) Common Terminology Criteria for Adverse Events (CTCAE) version 3.0 criteria.</p><p><strong>Results: </strong>Mean age of the patients was 60.43 ± 12.83. Primary tumor localization was the stomach in 33 patients (55%), colon in 21 (35%), rectum in five (8.3%), and appendix in one patient (1.7%). PCI mean value was 9.51 ± 10.92. CC-0 was applied in 37 (61.7%) patients, CC-1 in 11 (18.3%), CC-2 in 6 (10%), and CC-3 in six patients (10%). Morbidity was observed in 50 (83.33%) of the 60 patients participating in the study according to NCI-CTCAE v3.0 classification. Mild morbidity rate was 46.6%, severe morbidity rate was 36.6%, and mortality rate was 11.66%. Enteric diversion application, length of stay in the ICU, and length of hospital stay were shown to have a statistically significant effect on the NCI-CTCAE morbidity score (p= 0.046, p= 0.004, p <0.001).</p><p><strong>Conclusion: </strong>With proven beneficial effects on survival in patients with locally advanced gastrointestinal tumors, CRC and HIPEC are acceptable in these patients despite their increased morbidity and mortality rate. With new studies on this subject, morbidity and mortality rates may be reduced.</p>","PeriodicalId":23374,"journal":{"name":"Turkish Journal of Surgery","volume":"39 1","pages":"17-26"},"PeriodicalIF":0.6,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10234711/pdf/TJS-39-017.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9587963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dmitriy Plotkin, Umedzhon Gafarov, Mikhail Reshetnikov, Sergey Sterlikov, Elena Bogorodskaya
{"title":"Etiology and severity features of acute pancreatitis in HIV-positive patients with different immune status.","authors":"Dmitriy Plotkin, Umedzhon Gafarov, Mikhail Reshetnikov, Sergey Sterlikov, Elena Bogorodskaya","doi":"10.47717/turkjsurg.2023.5939","DOIUrl":"https://doi.org/10.47717/turkjsurg.2023.5939","url":null,"abstract":"<p><strong>Objectives: </strong>Acute pancreatitis is common in HIV-infected patients; however, the causes and severity of pancreatitis in HIV-positive patients have a number of significant features that affect both the severity of destruction of the pancreas and the methods of diagnosis and treatment.</p><p><strong>Material and methods: </strong>Anamnestic data, results of diagnosis and treatment of two groups of patients with acute pancreatitis were analyzed. The first group included 79 patients with acute pancreatitis combined with HIV infection who were admitted to the clinic for the period from 2017 to 2021. In people living with HIV, drugs and infectious agents caused acute pancreatitis in 11.4% and 24.1% of the cases, respectively. As our study showed, in patients with normal immune status, the drug etiology of pancreatitis prevailed in the structure of the causes of AP, in patients with immunodeficiency, infectious causes of pancreatitis were dominant.</p><p><strong>Results: </strong>According to the results of data analysis, it is clear that HIV infection is a factor that makes the course of pancreatitis about two times worse regardless of the presence of immunosuppression. The etiological structure of HIV-associated acute pancreatitis directly depends on the patient's immune status and differs in many ways from that of HIV-negative patients or patients receiving ART.</p><p><strong>Conclusion: </strong>The severity of the disease and the risk of death remain high in acute pancreatitis caused by infectious agents against the background of immunosuppression.</p>","PeriodicalId":23374,"journal":{"name":"Turkish Journal of Surgery","volume":"39 1","pages":"76-82"},"PeriodicalIF":0.6,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10234710/pdf/TJS-39-076.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9582652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Extreme cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in treatment of peritoneal metastasis.","authors":"Selman Sökmen, Tayfun Bişgin, Berke Manoğlu, Canan Altay, Hülya Ellidokuz","doi":"10.47717/turkjsurg.2023.5881","DOIUrl":"https://doi.org/10.47717/turkjsurg.2023.5881","url":null,"abstract":"<p><strong>Objectives: </strong>It was aimed to define the oncologic concept of \"extremeness\" in cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS/HIPEC) to determine morbidity-mortality results and final oncologic outcomes.</p><p><strong>Material and methods: </strong>Prospectively recorded data of 666 patients with peritoneal metastases who had undergone CRS/HIPEC between 2007 and 2020 were analyzed. Patients were divided into two groups as extreme (n= 371) and non-extreme (n= 295). Extreme CRS was defined as resection of ≥5 major organs or creation of ≥2 bowel anastomoses or peritoneal carcinomatosis index (PCI)≥ 15 or re-cytoreductive surgery.</p><p><strong>Results: </strong>More CC-1 or CC-2 cytoreduction (p <.001), increased mortality and morbidity (p <.001), prolonged operative time (p <.001), increased intraoperative erythrocyte suspension (p <.001), albumin (p <.001), fresh frozen plasma (FFP) (p <.001), and post-operative erythrocyte suspension (p <.001) usage were found in the extreme CRS/HIPEC group. Operative time, CC-1 or CC-2 cytoreduction, presence of ostomy, development of infection, and use of intra-operative albumin and FFP were found to be independent prognostic factors in Cox regression analysis. Three and five-year survival rates were significantly lower in the extreme CRS/HIPEC group (p <.001).</p><p><strong>Conclusion: </strong>High-volume peritoneal metastatic disease can be completely resected with extreme cytoreduction in carefully selected patients responsive to chemotherapy. Since the significant morbi-mortality related to the treatment of peritoneal metastasis is a real concern, it should be considered in experienced complex cancer centers that provides relatively better oncological outcomes compared to conventional treatments.</p>","PeriodicalId":23374,"journal":{"name":"Turkish Journal of Surgery","volume":"39 1","pages":"43-51"},"PeriodicalIF":0.6,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10234707/pdf/TJS-39-043.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9582650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The effect of different therapeutic treatments on the frequency of postoperative hypocalcemia in patients with thyroidectomy.","authors":"Hamdi Burak Piyade, Mahmut Başoğlu, Ersan Gürsoy","doi":"10.47717/turkjsurg.2023.5886","DOIUrl":"https://doi.org/10.47717/turkjsurg.2023.5886","url":null,"abstract":"<p><strong>Objectives: </strong>Thyroid gland surgery and its surgical complications are situations that a surgeon frequently encounters in his daily practice. In our study, it was aimed to examine the effect of different treatment methods given to patients who underwent thyroidectomy on hypocalcemia.</p><p><strong>Material and methods: </strong>Three hundred and seventy-one patients who underwent thyroidectomy at Ondokuz Mayıs University Medical Faculty General Surgery clinic between December 2016 and January 2021 were retrospectively included in the study. Parameters such as surgery indications, fine needle aspiration biopsy results, preoperative serum calcium values, type of surgery, serum calcium values at postoperative 1<sup>st</sup> day and 1<sup>st</sup> month, postoperative hospital stay, drugs prescribed at discharge, histopathological diagnosis of the patient, and whether there was incidental parathyroidectomy or not were included.</p><p><strong>Results: </strong>Mean age of 371 patients who underwent thyroidectomy was 49 (19-82) years. Total thyroidectomy was the most common type of thyroidectomy with 61% (n= 225) of the patients. There was a significant decrease in pre-op and post-op calcium values in all three types of surgery performed on the patients, and there was no significant difference between the different types of surgery. Post-operative day one and month one serum calcium values were significantly increased in all groups (p= .000). The increase in post-op serum calcium level was most common in the group using calcium carbonate + cholecalciferol + calcitriol.</p><p><strong>Conclusion: </strong>The use of post-op calcitriol in patients undergoing thyroidectomy seems to be quite effective in preventing the development of hypocalcemia.</p>","PeriodicalId":23374,"journal":{"name":"Turkish Journal of Surgery","volume":"39 1","pages":"70-75"},"PeriodicalIF":0.6,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10234705/pdf/TJS-39-070.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9587965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Laparoscopic appendectomy: Effectiveness in children with generalized and advanced generalized peritonitis cases.","authors":"Osman Uzunlu, İncinur Genişol","doi":"10.47717/turkjsurg.2023.5707","DOIUrl":"https://doi.org/10.47717/turkjsurg.2023.5707","url":null,"abstract":"<p><p>Laparoscopic appendectomy is one of the most common surgical procedures in treating pediatric appendicitis. This study aimed to investigate the efficacy of laparoscopic surgery in cases complicated with advanced generalized peritonitis in the pediatric population. The study retrospectively reviewed 55 cases of children who underwent laparoscopic appendectomies. The cases were classified as uncomplicated, complicated, or advanced generalized peritonitis. Laboratory results, diagnostic algorithms, surgical techniques, and complications were investigated. Twenty-four of the cases were boys and 31 were girls. Mean age was 11.3 ± 3 years. Twenty of the cases (36%) were uncomplicated and 35 (64%) were complicated. Nine of the complicated cases presented advanced generalized peritonitis and were additionally classified as \"another special group\". Mean leukocyte count and C-reactive protein levels were measured respectively as 22.49 ± 12 x 10<sup>9</sup> /L and 120.5 ± 99 mg/L in complicated cases and as 17.06 ± 10 x 10<sup>9</sup> and 52.37 ± 69 mg/L in uncomplicated cases. All advanced generalized peritonitis cases had presented to the hospital with intestinal obstruction and had diffuse abdominal rigidity on physical exam. None of the cases had any complications in the intraoperative or early postoperative period. Infection complications (namely, intra-abdominal abscesses and surgical site infections) were observed in four cases (7%) in the postoperative period. Mean length of hospital stay was 5.62 ± 2.6 days and 3.95 ± 1 days in complicated and uncomplicated cases, respectively. Mean length of stay in advanced generalized peritonitis cases was 8.33 ± 2 days. It was observed that laparoscopic appendectomy might be the first choice of treatment option in cases complicated with advanced generalized peritonitis.</p>","PeriodicalId":23374,"journal":{"name":"Turkish Journal of Surgery","volume":"39 1","pages":"52-56"},"PeriodicalIF":0.6,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10234713/pdf/TJS-39-052.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9587961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Caner Doğan, Ersin Borazan, Latif Yılmaz, Ahmet A Balık
{"title":"How much is the long-term quality of life impaired in cholecystectomy-related biliary tract injury?","authors":"Caner Doğan, Ersin Borazan, Latif Yılmaz, Ahmet A Balık","doi":"10.47717/turkjsurg.2023.5780","DOIUrl":"https://doi.org/10.47717/turkjsurg.2023.5780","url":null,"abstract":"<p><strong>Objectives: </strong>Iatrogenic bile duct injury (IBDI) is a serious complication of cholecystectomy that may crucially affect long-term quality of life and have major morbidities. Furthermore, even after reconstructive surgical treatment, such injuries still reduce the long-term quality of life. Therefore, there remains a need to investigate long-term quality of life of the patients since it is considered that there is a long-term decrease in both physical and mental quality of life. Accordingly, this study aimed to investigate the clinical evaluations and long-term quality of life of the patients who had undergone reconstructive surgery for iatrogenic bile duct injury.</p><p><strong>Material and methods: </strong>This clinical study included 49 patients (38 females/11 males) with cholecystectomy-associated bile duct injury and who underwent reconstruction surgery. Several parameters, including the type of bile duct injury, reconstructive surgical procedures, length of hospital stay, and complications were evaluated. Moreover, the effects of reconstructive surgical timing (perioperative, early postoperative, late postoperative) on quality of life were assessed. Long term quality of life (LTQL) levels were evaluated using the SF-36 questionnaire in patients whose follow-ups ranged from two to nine years. The SF-36 questionnaire scores were compared to the average SF-36 norm values of the healthy Turkish population.</p><p><strong>Results: </strong>Our results showed that 73.5% of biliary tract injuries occurred after a laparoscopic surgery while 26.5% after open cholecystectomy. Of the injuries, 32.7% developed in patients with acute cholecystitis. Thirty of the patients were treated with hepaticojejunostomy. When SF-36 questionnaire scores of the study were compared to those of the healthy Turkish population, energy-vitality was found to be lower significantly in male patients (p= 0.041). However, there was no significant deterioration in female patients. Although general health perception was better in hepaticojejunostomy according to the type of reconstructive surgery performed, no significant difference was observed in the quality of life. Mental health, energy-vitality (p= 0.019), and general health perception (p= 0.026) were found to be lower in women who had E<sup>1</sup> -E<sup>2</sup> injuries. Only seven of the injuries were detected perioperatively. Physical function (p= 0.033) and general health perception (p= 0.035) were found to be lower in the early postoperative treatment group in male patients in terms of the time of reconstructive surgery.</p><p><strong>Conclusion: </strong>IBDIs cause serious morbidity. Furthermore, even after reconstructive surgical treatment, such injuries still reduce LTQL. Our results suggest that LTQL is lower, especially in male patients undergoing postoperative early biliary repair for Strasberg E<sup>3</sup> -E<sup>4</sup> type injuries.</p>","PeriodicalId":23374,"journal":{"name":"Turkish Journal of Surgery","volume":"39 1","pages":"34-42"},"PeriodicalIF":0.6,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10234714/pdf/TJS-39-034.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9582657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Selman Alkan, Murat Çakır, Mustafa Şentürk, Alper Varman, Gülçin Büyükbezirci, Mehmet Aykut Yıldırım, Mehmet Biçer
{"title":"Changes in cerebral oxygen saturation with the Trendelenburg position and increased intraabdominal pressure in laparocopic rectal surgery.","authors":"Selman Alkan, Murat Çakır, Mustafa Şentürk, Alper Varman, Gülçin Büyükbezirci, Mehmet Aykut Yıldırım, Mehmet Biçer","doi":"10.47717/turkjsurg.2023.5890","DOIUrl":"https://doi.org/10.47717/turkjsurg.2023.5890","url":null,"abstract":"<p><strong>Objectives: </strong>Position changes and increased intra-abdominal pressure in laparoscopic interventions lead to some physiopathological changes. There is no definite information in the literature regarding cerebral oxygen saturation in patients undergoing colorectal surgery. Our aim was to investigate whether there is oxygen saturation change in the brain tissue in pneumoperitoneum and the Trendelenburg position during laparoscopic rectal surgery.</p><p><strong>Material and methods: </strong>Cerebral oxygen saturation was measured in 35 patients who underwent laparoscopic rectal surgery in the Trendelenburg position. Measurements were made under general anesthesia in the pneumoperitoneum and the Trendelenburg position.</p><p><strong>Results: </strong>The values that are statistically affected by the position are systolic blood pressure, mean arterial blood pressure and cerebral oxygen saturation. The Trendelenburg position does not disturb the cerebral oxygen saturation and it causes an increase in saturation. After pneumoperitoneum occurred, changes in systolic blood pressure, mean arterial blood pressure and brain oxygen saturation were detected. Cerebral oxygen saturation increases with the formation of pneumoperitoneum.</p><p><strong>Conclusion: </strong>The Trendelenburg position and increased intraabdominal pressure during laparoscopic rectal surgery do not impair brain oxygen saturation.</p>","PeriodicalId":23374,"journal":{"name":"Turkish Journal of Surgery","volume":"39 1","pages":"57-62"},"PeriodicalIF":0.6,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10234706/pdf/TJS-39-057.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9582651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"FROM THE EDITOR'S DESK.","authors":"Kaya Sarıbeyoğlu","doi":"10.47717/turkjsurg.2023.230101","DOIUrl":"https://doi.org/10.47717/turkjsurg.2023.230101","url":null,"abstract":"","PeriodicalId":23374,"journal":{"name":"Turkish Journal of Surgery","volume":"39 1","pages":"AXV"},"PeriodicalIF":0.6,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10234709/pdf/TJS-39-axv.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9578917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}