{"title":"Role of bioactive collagen peptide in the management of monoidoacetate induced osteoarthritis and its comparison with diacerein in rat model: An experimental study","authors":"Ravi Kant, P. Rao, Gyaneshwer Tank, Rohit Gupta","doi":"10.4103/jbjd.jbjd_32_22","DOIUrl":"https://doi.org/10.4103/jbjd.jbjd_32_22","url":null,"abstract":"Osteoarthritis is the most common joint disorder. Currently, there are no stabilized pharmacological agents capable of retarding the progression or preventing OA. This is a fundamental and important area of current research. Therefore, the present study was to investigate the action of Bioactive Collagen peptide against Monosodium Iodoacetate induced Osteoarthritis in rat models and its comparison with Diacerein. Nine experimental groups were taken. Osteoarthritis was induced by intraarticular injection of Monosodium Iodoacetate (MIA) in knee joints. Bioactive Collagen peptide was given to groups 7, 8 and 9 for 1, 2 and 3 months respectively, then histopathological examination was done. Diacerein was given to groups 4, 5 and 6 for 1, 2 and 3 months respectively followed by histopathological scoring. Significant (P < 0.05) chondroprotection was observed after treatment of Bioactive Collagen peptide when compared with MIA control group as well as Placebo treated group. Significant improvement was also observed when compared with Diacerein treated groups for 1 and 2 monthsIt was concluded that both Bioactive Collagen Peptide and Diacerein are potent chondroprotective agent, but Collagen peptide is far better than Diacerein.","PeriodicalId":232675,"journal":{"name":"Journal of Bone and Joint Diseases","volume":"48 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124483044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T. Arun Babu, Jahangir Ahmed Naseem, CG Delhi Kumar
{"title":"Iliac crest osteomyelitis: A rare complication of bone marrow aspiration in a 12-year-old boy with aplastic anemia","authors":"T. Arun Babu, Jahangir Ahmed Naseem, CG Delhi Kumar","doi":"10.4103/jbjd.jbjd_7_22","DOIUrl":"https://doi.org/10.4103/jbjd.jbjd_7_22","url":null,"abstract":"","PeriodicalId":232675,"journal":{"name":"Journal of Bone and Joint Diseases","volume":"65 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114166673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Kumar, S. Singh, Siddharth Deshwal, Zohaib Abbas, Ashish Kumar
{"title":"A rare case report: Giant cell tumor of ischial tuberosity and ischiopubic ramus","authors":"D. Kumar, S. Singh, Siddharth Deshwal, Zohaib Abbas, Ashish Kumar","doi":"10.4103/jbjd.jbjd_22_22","DOIUrl":"https://doi.org/10.4103/jbjd.jbjd_22_22","url":null,"abstract":"The ischial tuberosity and ischiopubic ramus represent one of the rarest sites of giant cell tumors of bone. A rare case is presented here. The unusual site and characteristic features of giant cell tumors and current treatment options are reviewed.","PeriodicalId":232675,"journal":{"name":"Journal of Bone and Joint Diseases","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116735700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sarvesh Pandey, R. Khare, A. Yadav, Devender Deswal, Sankalp Jaiswal
{"title":"Functional outcome of arthroscopic anterior cruciate ligament reconstruction using variable loop cortical suspensory fixation","authors":"Sarvesh Pandey, R. Khare, A. Yadav, Devender Deswal, Sankalp Jaiswal","doi":"10.4103/jbjd.jbjd_23_22","DOIUrl":"https://doi.org/10.4103/jbjd.jbjd_23_22","url":null,"abstract":"Anterior cruciate ligament (ACL) injury is more common in men than women. Variable loop cortical suspensory fixation is an excellent graft fixation device, which provides an option for further tightening the graft even after the tibial end fixation is done if the surgeon feels it is needed. At 3-month follow-up, ACL reconstruction using the novel variable loop cortical suspensory fixation device granted an improvement in mean LYSHOLM score from 19.91 preoperatively to 85.59 at 3-month follow-up, which is a statistically very significant clinical and functional outcome. The principal advantage of the ACL reconstruction using variable loop cortical suspensory fixation is that it uses the ability to re-tension the graft after tibial fixation. A taut ACL construct is crucial during postoperative rehabilitation to reduce the risk of knee instability and re-rupture of the ACL graft. We conclude that the technique described here is a simple, robust, and effective approach to minimize graft laxity, and thereby leave a snug ACL construct. In addition, re-tensioning of the graft after tibial fixation eliminates the need for a posterior drawer on the knee, as the resulting laxity will be removed with re-tensioning.","PeriodicalId":232675,"journal":{"name":"Journal of Bone and Joint Diseases","volume":"46 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116519794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C. Pal, K. Dinkar, R. Kapoor, Shailesh Kumar, Ashutosh Verma, Jeetesh V. Patel
{"title":"To evaluate the efficacy of antibiotic-coated intramedullary locking nail in the compound fracture of tibia","authors":"C. Pal, K. Dinkar, R. Kapoor, Shailesh Kumar, Ashutosh Verma, Jeetesh V. Patel","doi":"10.4103/jbjd.jbjd_17_22","DOIUrl":"https://doi.org/10.4103/jbjd.jbjd_17_22","url":null,"abstract":"Introduction: Soft tissue with skeletal infections remains a big problem for orthopaedic surgeons. Bone provides a unique milieu for bacteria, with low vascularity and turnover rate. Biofilm-forming bacteria cause most orthopaedic trauma infections. When biofilm is formed, it protects the microorganism from antimicrobial treatment thus leading to chronic infections. Antibiotic-coated interlocking nail locally releases gentamycin + PDLLA at initial high concentrations followed by a period of constant release. The biodegradable polymer (PDLLA) is excreted from the body through the tricorboxylic acid cycle cycle, combined with gentamycin for sustained release. Materials and Methods: This was a prospective interventional study conducted between September 2018 and August 2020. In this period, we analyzed the hospital records to find out the cases treated by antibiotic-coated intramedullary locking nails. A total of 30 cases of compound tibia fracture were included in our study. Patients were routinely followed at definite intervals and specifically assessed for radiographic and functional evaluation by using the RUST score. Results: Out of 30 patients, radiological union at 6 months using the RUST score was 4 in 10.00% patients, 8 in 13.33% patients, 10 in 23.33% patients and 12 in 53.33% patients and final functional outcome was “excellent” in 53.33% patients, “good” in 23.33% patients, “fair” in13.33 % patients and “poor” in 10.00% patients. Conclusion: Antibiotic-coated tibia interlocking nail yields good functional outcomes with fewer complications in these fractures. Antibiotic tibia interlocking nail is a good treatment option and should be used whenever indicated.","PeriodicalId":232675,"journal":{"name":"Journal of Bone and Joint Diseases","volume":"119 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127734195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Neglected quadriceps tendon rupture: A case report","authors":"Siddharth Singh, Pulak Sharma","doi":"10.4103/jbjd.jbjd_21_22","DOIUrl":"https://doi.org/10.4103/jbjd.jbjd_21_22","url":null,"abstract":"Quadriceps tendon rupture is an unusual injury, mostly occurring in the middle-aged population involved in athletic activities. Patients with such injuries present with a history of trauma, which may be direct or indirect, associated with swelling and inability to actively extend the knee. When associated with minor trauma, the concurrent presence of chronic diseases and the long-term use of certain medications should be looked for. Neglected traumatic quadriceps tendon rupture is very rare. Our patient presented with a neglected quadriceps tendon rupture of the left knee due to injury sustained 6 months. Consent was taken from him to be used as a case report. The patient had full recovery after surgery and physiotherapy. The index case report is important as the patient had delayed presentation in such a rare injury.","PeriodicalId":232675,"journal":{"name":"Journal of Bone and Joint Diseases","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128909084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ritu Ojha, Rahul Patel, I. Kumar, Vritika Bhardwaj, A. Verma, R. Shukla
{"title":"Magnetic resonance imaging evaluation of patients with anterior knee pain: A prospective observational study","authors":"Ritu Ojha, Rahul Patel, I. Kumar, Vritika Bhardwaj, A. Verma, R. Shukla","doi":"10.4103/jbjd.jbjd_10_22","DOIUrl":"https://doi.org/10.4103/jbjd.jbjd_10_22","url":null,"abstract":"Anterior knee pain (AKP) is one of the most common clinical conditions related to knee pathology among the athletes and young adults. The identification of pain provoking factor is crucial for the better outcome of the treatment. Many patients with AKP have disabling pain and significant disability, but the physical signs and radiological findings are unremarkable. Its aetiology is still not fully understood, but there are some major factors that can be attributed to its aetiology. Accurate diagnosis of the condition is needed before any decision regarding its management is undertaken. Diagnosis is usually suspected clinically and is confirmed by imaging. Although, radiography, ultrasonography, computed tomography scan and magnetic resonance imaging (MRI) are the available modalities for the evaluation of AKP, MRI is considered the gold standard for pain imaging and can provide important information regarding individually tailored treatment. The present study is a prospective descriptive compilation of the role of available imaging modalities, particularly MRI in the evaluation of different pathological conditions related to AKP. The present study demonstrated that patellofemoral instability was a major cause for origin of AKP.","PeriodicalId":232675,"journal":{"name":"Journal of Bone and Joint Diseases","volume":"2020 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122433794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohammad Julfiqar, A. Khan, Isna Khan, Zainab Motiwala, Ch.Shyamsunder Singh, Arshad Rehman Mohammad
{"title":"An adult with elbow dislocation with entrapped osteochondral fragment of olecranon","authors":"Mohammad Julfiqar, A. Khan, Isna Khan, Zainab Motiwala, Ch.Shyamsunder Singh, Arshad Rehman Mohammad","doi":"10.4103/jbjd.jbjd_8_22","DOIUrl":"https://doi.org/10.4103/jbjd.jbjd_8_22","url":null,"abstract":"In this case report, we present a young adult presenting with a traumatic elbow dislocation with an entrapped osteochondral fragment. An initial diagnosis of traumatic elbow dislocation with entrapped medial epicondyle was made but later on it was found to be an osteochondral fragment detached from the olecranon fragment. The patient required surgical intervention to restore a congruent and stable elbow joint. This case report is novel as the elbow dislocation with osteochondral fragment entrapment is occurring in an adult; at the same time, the fragment belongs to the olecranon, and cases of which have not been reported yet.","PeriodicalId":232675,"journal":{"name":"Journal of Bone and Joint Diseases","volume":"72 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121612008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bilateral elbow terrible triad case report","authors":"Amit Saraf, S. Bishnoi, A. Hussain, S. Aggarwal","doi":"10.4103/jbjd.jbjd_14_22","DOIUrl":"https://doi.org/10.4103/jbjd.jbjd_14_22","url":null,"abstract":"A 33-year-old male presented to our casualty department with pain and swelling accompanied by bony deformity over bilateral elbows post an episode of high-energy trauma. Plain radiographs and 3d-CT were done which showed Terrible Triad injuries to both the elbows. Different surgical managements were planned and executed in both elbows according to the fracture patterns. The postoperative period was uneventful and the patient was under continuous follow-up. At the 1-year follow-up patient showed good radiological and functional recovery.","PeriodicalId":232675,"journal":{"name":"Journal of Bone and Joint Diseases","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127765515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bilateral anterior shoulder dislocation following tramadol induced seizure after low dose consumption in a healthy adult","authors":"V. Saxena, Raju Vaishya","doi":"10.4103/jbjd.jbjd_12_22","DOIUrl":"https://doi.org/10.4103/jbjd.jbjd_12_22","url":null,"abstract":"Tramadol is a synthetic analgesic used for the treatment of moderate to severe pain with a dual mechanism of action. Although Tramadol-induced seizures are reported in the literature, however, the incidence is rare with its use in therapeutic dosage. Bilateral symmetrical anterior dislocation following a seizure is an unusual complication. We present a rare case of bilateral symmetrical anterior shoulder dislocation following Tramadol-induced epileptiform reaction in an otherwise healthy adult male. The dislocations were diagnosed early and reduced immediately with a satisfactory outcome. An awareness of this entity and a high index of suspicion are required to make an early diagnosis and offer prompt treatment in order to avoid unpleasant complications.","PeriodicalId":232675,"journal":{"name":"Journal of Bone and Joint Diseases","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127983293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}