Transfusion Clinique et Biologique最新文献

Fragile beginnings enduring legacy: the blood bag story 脆弱的开端持久的遗产：血袋的故事。

IF 1.2 4区医学

Transfusion Clinique et Biologique Pub Date : 2025-08-01 DOI: 10.1016/j.tracli.2025.04.005

Manish Raturi , Aaditya Shivhare

引用次数: 0

Bridging the evidence chasm: reflections on the WHO sickle cell disease in pregnancy guideline 弥合证据鸿沟：对世卫组织妊娠镰状细胞病指南的反思。

IF 1.2 4区医学

Transfusion Clinique et Biologique Pub Date : 2025-08-01 DOI: 10.1016/j.tracli.2025.06.007

Radheshyam Meher, Himanshi Devi, Raj Narayan Swain

引用次数: 0

The future of quality management in transfusion medicine – From the new SoHO regulation and beyond 输血医学质量管理的未来-从新的SoHO条例和超越。

IF 1.2 4区医学

Transfusion Clinique et Biologique Pub Date : 2025-08-01 DOI: 10.1016/j.tracli.2025.07.001

Tomislav Vuk

{"title":"The future of quality management in transfusion medicine – From the new SoHO regulation and beyond","authors":"Tomislav Vuk","doi":"10.1016/j.tracli.2025.07.001","DOIUrl":"10.1016/j.tracli.2025.07.001","url":null,"abstract":"<div><div>On July 17, 2024, the Regulation (EU) 2024/1938 on standards of quality and safety for substances of human origin intended for human application was published. The new Regulation promotes high quality and safety standards, enhanced protection of donors and patients, harmonisation across Member States, continuity of supply and preparedness for emergency situations.</div><div>Future developments in quality management and the accompanying challenges will be influenced by the changed legislative framework, but more in terms of strengthening or expanding the existing requirements than introducing new requirements or significantly changing existing practices. By referring to the EDQM and ECDC guidelines to achieve compliance with the standards set out in the Regulation, timely alignment with scientific progress and best practices as well as a timely response to new threats is enabled. Adapting to more rapid changes may prove challenging for the quality management system, which should ensure timely, controlled, and documented implementation of new or changed requirements and maintain an adaptable monitoring system.</div><div>The new Regulation places a strong emphasis on SoHO preparation authorization, risk management and emergency planning. In addition, traceability and vigilance requirements have also been enhanced. Quality management staff will play an important role in supporting the implementation of these requirements, setting priorities, coordinating activities, creating documents, etc. Even in well-developed quality systems, it will be necessary to provide additional education and training of staff, and if necessary, other resources for the effective implementation of all requirements.</div><div>International cooperation will become increasingly important in the harmonization of standards and definitions, quality monitoring and benchmarking, and sharing of best practices.</div></div>","PeriodicalId":23262,"journal":{"name":"Transfusion Clinique et Biologique","volume":"32 3","pages":"Pages 321-324"},"PeriodicalIF":1.2,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144602713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exploring the pattern of blood utilization in various obstetric scenarios unfolding within the wall of tertiary care centre: A prospective study from western India 探索血液利用的模式在各种产科方案展开在三级保健中心的墙：从印度西部的前瞻性研究。

IF 1.2 4区医学

Transfusion Clinique et Biologique Pub Date : 2025-08-01 DOI: 10.1016/j.tracli.2025.04.002

Nishith Nayan , Shweta Ranjan , Rakesh Kumar , Jitendra Patel , Nilamben Prajapati , Priyatma Kumari

{"title":"Exploring the pattern of blood utilization in various obstetric scenarios unfolding within the wall of tertiary care centre: A prospective study from western India","authors":"Nishith Nayan , Shweta Ranjan , Rakesh Kumar , Jitendra Patel , Nilamben Prajapati , Priyatma Kumari","doi":"10.1016/j.tracli.2025.04.002","DOIUrl":"10.1016/j.tracli.2025.04.002","url":null,"abstract":"<div><h3>Background and objectives</h3><div>With increasing demand for blood components being unable to meet the supply in developing countries, there is a need to implement strategies for rational use of blood components. Present study aims to evaluate transfusion practices in obstetric emergencies in a hospital-based blood centre.</div></div><div><h3>Material and methods</h3><div>The study was conducted from November 2020 to October 2021, focussing on obstetric in-patients who requested blood transfusions. Requests were processed and cross-matched following the hospital’s transfusion guidelines. The data on clinical conditions and blood transfusion details were analysed to evaluate the use of blood and blood components in relation to the patients’ diagnosis.</div></div><div><h3>Results</h3><div>Out of 6,753 obstetric cases admitted, 334 patients requested blood components. Blood components were transfused to 271 (81.1%) patients. Total 927 units were used, out of which 57.1% were packed red blood cells. Most common indications were atonic postpartum haemorrhage (36.8%), placental abruption (23.7%) and placenta previa (16.5%). Crossmatch-to-Transfusion Ratio was 1.5, Transfusion Probability was 81.1%, Transfusion Index was 2.8, and Maximum Blood Ordering Schedule was 4.2.</div></div><div><h3>Conclusion</h3><div>Standard Operating Procedure for an efficient blood ordering policy should be developed and strict adherence to established blood transfusion guidelines must be ensured. Over-ordering can lead to unnecessary reservations and subsequent shortages. Emphasis on appropriate use of blood components to ensure their effective management is crucial.</div></div>","PeriodicalId":23262,"journal":{"name":"Transfusion Clinique et Biologique","volume":"32 3","pages":"Pages 265-271"},"PeriodicalIF":1.2,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144061742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Transfusion strategy and allo-immunization to red blood cell antigens after allogeneic hematopoietic stem cell transplantation with partial donor/recipient Rh matching 供体/受体rh部分匹配的异体造血干细胞移植后输血策略和对红细胞抗原的同种免疫。

IF 1.2 4区医学

Transfusion Clinique et Biologique Pub Date : 2025-08-01 DOI: 10.1016/j.tracli.2025.06.001

Jeromine Beaufort , Alienor Xhaard , Aline Floch , Marie Robin , Flore Sicre de Fontbrune , David Michonneau , Florian Chevillon , Nathalie Dhedin , Matthieu Jestin , Eleonore Kaphan , Pedro Henrique de Lima Prata , Mathilde Ruggiu , Richard Traineau , Candice Cavalie , Gerard Socie , Regis Peffault de Latour , Anne-Claire Lepretre

{"title":"Transfusion strategy and allo-immunization to red blood cell antigens after allogeneic hematopoietic stem cell transplantation with partial donor/recipient Rh matching","authors":"Jeromine Beaufort , Alienor Xhaard , Aline Floch , Marie Robin , Flore Sicre de Fontbrune , David Michonneau , Florian Chevillon , Nathalie Dhedin , Matthieu Jestin , Eleonore Kaphan , Pedro Henrique de Lima Prata , Mathilde Ruggiu , Richard Traineau , Candice Cavalie , Gerard Socie , Regis Peffault de Latour , Anne-Claire Lepretre","doi":"10.1016/j.tracli.2025.06.001","DOIUrl":"10.1016/j.tracli.2025.06.001","url":null,"abstract":"<div><h3>Background</h3><div>After allogeneic hematopoietic stem cell transplantation (alloHSCT), the HAS recommends transfusing red blood cells (RBCs) matched for Rh (“Rhesus”) phenotypes, and the EFS recommends respecting both donor and recipient Rh phenotypes. We previously reported a 10.3% allo-immunization rate in 58 Rh-incompatible alloHSCT recipients transfused in the donor phenotype: none was directed against the mismatched donor Rh antigens.</div></div><div><h3>Study design and methods</h3><div>In this single-center retrospective study, we investigated the incidence of allo-immunization to RBC antigens during the first year after alloHSCT in 264 patients with partial donor/recipient Rh matching, and transfused from alloHSCT with RBCs expressing at least one donor Rh antigen absent from the recipient.</div></div><div><h3>Results</h3><div>Six patients had a positive RBC antibody screening test (allo-immunization rate: 2.3%). In five cases, the antibodies were unrelated to the transfusion strategy. One patient presented a temporary anti-C, possibly related to the transfusion strategy, occurring in a context of immune hemolytic anemia.</div></div><div><h3>Discussion</h3><div>Our findings indicate that the transfusion of RBC in the donor Rh phenotype is associated with a low rate of immunization to RBC antigens. These results question the current transfusion guidelines in alloHSCT recipients, aiming to limit the use of short-supply RBCs phenotypes.</div></div>","PeriodicalId":23262,"journal":{"name":"Transfusion Clinique et Biologique","volume":"32 3","pages":"Pages 292-297"},"PeriodicalIF":1.2,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144251700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Donor-reported stress type affects inflammatory blood markers prior to donation 献血者报告的应激类型影响捐献前的炎症血液标志物。

IF 1.2 4区医学

Transfusion Clinique et Biologique Pub Date : 2025-08-01 DOI: 10.1016/j.tracli.2025.06.004

Fabrice Cognasse , Marco Heestermans , Charles-Antoine Arthaud , Marie-Ange Eyraud , Amelie Prier , Jacques Chiaroni , Bruno Danic , Pierre Tiberghien , Elisabeth Huis in ’t Veld , Barbara Masser , Anne-Claire Duchez , Hind Hamzeh-Cognasse

{"title":"Donor-reported stress type affects inflammatory blood markers prior to donation","authors":"Fabrice Cognasse , Marco Heestermans , Charles-Antoine Arthaud , Marie-Ange Eyraud , Amelie Prier , Jacques Chiaroni , Bruno Danic , Pierre Tiberghien , Elisabeth Huis in ’t Veld , Barbara Masser , Anne-Claire Duchez , Hind Hamzeh-Cognasse","doi":"10.1016/j.tracli.2025.06.004","DOIUrl":"10.1016/j.tracli.2025.06.004","url":null,"abstract":"<div><h3>Background and objectives</h3><div>Psychosocial stressors may contribute to inflammation. The aim of this study was to assess soluble inflammatory markers in blood donors’ while they donated, focusing on perceived stress from family, work or from the act of donating.</div></div><div><h3>Materials and methods</h3><div><span>Donors answered yes/no questions about stress (family, work, or donation-related) and rated puncture pain (0–9). Blood samples were centrifuged and analyzed by ELISA for inflammatory markers, including cortisol, </span>RANTES, sCD40L, IL-2, IL-4, IL-6, IL-10, and serotonin, focusing on platelet-derived inflammatory factors.</div></div><div><h3>Results</h3><div>Cortisol levels were higher in donors who experienced blood donation related stress as compared to donors who did not experience any type of stress. The molecule RANTES was only significantly higher in donors who experienced family stress. A significant increase in the concentration of sCD40L in the plasma of the whole sample and female donors is observed only in the group who only experienced stress related to blood donation, but not family or work-related stress.</div></div><div><h3>Conclusion</h3><div>These findings suggest that stress experienced before blood donation may influence the inflammatory profile of blood components. Further research is needed to explore the impact of donors’ experiences of psychosocial stressors on transfusion outcomes and on blood components characteristics.</div></div>","PeriodicalId":23262,"journal":{"name":"Transfusion Clinique et Biologique","volume":"32 3","pages":"Pages 315-320"},"PeriodicalIF":1.2,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144340732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Therapeutic plasma exchange in treatment of autoimmune retinopathy 血浆置换治疗自身免疫性视网膜病变

IF 1.2 4区医学

Transfusion Clinique et Biologique Pub Date : 2025-08-01 DOI: 10.1016/j.tracli.2025.05.003

Yigit Baykara, Muharrem Yunce

引用次数: 0

From ‘Aww to Wow’: emerging role of transfusion medicine in fecal microbiota transplantation 从“哇到哇”：输血医学在粪便微生物群移植中的新兴作用。

IF 1.2 4区医学

Transfusion Clinique et Biologique Pub Date : 2025-08-01 DOI: 10.1016/j.tracli.2025.05.004

Radheshyam Meher

引用次数: 0

The 8-Model framework: a strategic roadmap for patient blood management implementation- A critical commentary 8模型框架：患者血液管理实施的战略路线图-关键评论。

IF 1.2 4区医学

Transfusion Clinique et Biologique Pub Date : 2025-08-01 DOI: 10.1016/j.tracli.2025.04.006

Radheshyam Meher

引用次数: 0

ABC of teaching and learning in transfusion medicine: Time for transformation 输血医学教与学的ABC：转型的时机。

IF 1.2 4区医学

Transfusion Clinique et Biologique Pub Date : 2025-08-01 DOI: 10.1016/j.tracli.2025.04.004

Radheshyam Meher

引用次数: 0