Transfusion Clinique et Biologique最新文献

{"title":"Can artificial blood improve blood availability and transfusion safety in low-resource countries?","authors":"Wassim Hamadeh , Antoine Haddad , Ahmad Ibrahim","doi":"10.1016/j.tracli.2026.01.002","DOIUrl":"10.1016/j.tracli.2026.01.002","url":null,"abstract":"","PeriodicalId":23262,"journal":{"name":"Transfusion Clinique et Biologique","volume":"33 2","pages":"Pages 67-68"},"PeriodicalIF":1.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145919490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"When screening works but systems fail: Closing the implementation gap in platelet transfusion refractoriness","authors":"RishiRaj Sinha","doi":"10.1016/j.tracli.2026.02.004","DOIUrl":"10.1016/j.tracli.2026.02.004","url":null,"abstract":"","PeriodicalId":23262,"journal":{"name":"Transfusion Clinique et Biologique","volume":"33 2","pages":"Pages 140-141"},"PeriodicalIF":1.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146196342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Managing the blood supply in Lebanon: response to the 2024 regional conflict","authors":"Rita Feghali ,&nbsp;Tarek Bou Assi ,&nbsp;Firass Abiad ,&nbsp;Olivier Garraud ,&nbsp;Antoine Haddad","doi":"10.1016/j.tracli.2026.01.010","DOIUrl":"10.1016/j.tracli.2026.01.010","url":null,"abstract":"<div><h3>Background</h3><div>Lebanon’s fragmented blood transfusion system faces major risks during humanitarian crises. We describe the national blood-supply response to a mass-casualty event (the pager explosion, Sept 17, 2024) followed by a two-month escalation of hostilities (Sept 21–Nov 20, 2024). The objective is to evaluate the effectiveness, operational challenges, and lessons learned from the coordinated Ministry of Public Health (MOPH) – Lebanese Red Cross (LRC) blood management response during this crisis.</div></div><div><h3>Materials and methods</h3><div>Retrospective review of MOPH reports, LRC dashboard data, meeting minutes, and quarterly narrative reports covering the acute (72 h after the explosion) and chronic (two-month war) phases. Key operational metrics (units collected, units distributed, delivery missions, donor characteristics) were extracted and summarized.</div></div><div><h3>Results</h3><div>The Pager explosion injured around 2750 people. Over the first 72 h the LRC prepared and delivered 373 packed red blood cells (PRBCs) to 25 hospitals in 48 missions (median delivery time 1.5 h) and collected more than 900 donor units (61% first-time donors). During the subsequent two-month conflict, the LRC distributed 2481 PRBCs and 1150 fresh frozen plasma units to 56 hospitals, despite center damage, security restrictions, staff fatigue, and declining donor turnout. Centralized command, real-time inventory visibility, pre-approved transport clearances, donor management, and targeted communication sustained supply and safety.</div></div><div><h3>Conclusion</h3><div>Rapid centralization of coordination, real-time data sharing, standardized communication, and predefined protocols preserved transfusion capacity in an extreme, resource-limited crisis. Institutionalizing these mechanisms and integrating all hospital blood banks would strengthen national transfusion resilience and offer a scalable model for other low- and middle-income settings.</div></div>","PeriodicalId":23262,"journal":{"name":"Transfusion Clinique et Biologique","volume":"33 2","pages":"Pages 84-88"},"PeriodicalIF":1.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146109486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Potential application of artificial oxygen carriers in perioperative setting for solid organ malignancies","authors":"Naveen Bansal ,&nbsp;Yashik Bansal ,&nbsp;Shivani Choudhary ,&nbsp;Charu Singh","doi":"10.1016/j.tracli.2026.01.007","DOIUrl":"10.1016/j.tracli.2026.01.007","url":null,"abstract":"","PeriodicalId":23262,"journal":{"name":"Transfusion Clinique et Biologique","volume":"33 2","pages":"Pages 138-139"},"PeriodicalIF":1.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146055787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of social media, influencers, and online communities in blood donor recruitment and retention: A systematic scoping review","authors":"RishiRaj Sinha ,&nbsp;Arun V ,&nbsp;R. Sravan Kumar ,&nbsp;Rashmi Jain","doi":"10.1016/j.tracli.2026.03.001","DOIUrl":"10.1016/j.tracli.2026.03.001","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Background&lt;/h3&gt;&lt;div&gt;Blood services worldwide continue to face persistent challenges in recruiting and retaining voluntary, non-remunerated blood donors, particularly among younger populations. Over the past decade, communication strategies have shifted from traditional mass media to digital environments, where social media platforms, influencers, and online communities increasingly shape social norms, identity formation, and prosocial behaviour. These digital tools are now widely used to mobilise blood donors; however, the existing evidence base remains fragmented across disciplines, regions, and study designs.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Objectives&lt;/h3&gt;&lt;div&gt;This scoping review aims to map and synthesise the available evidence on the role of social media, influencers, and online communities in blood donor recruitment and retention. It further seeks to identify key mechanisms underlying digital engagement, highlight knowledge gaps, and propose a digital sociology-informed framework to guide “next-generation” donor engagement strategies.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Methods&lt;/h3&gt;&lt;div&gt;A scoping review was conducted in accordance with PRISMA-ScR guidance. Major databases (PubMed, Scopus, Web of Science, PsycINFO, and CINAHL) and relevant grey literature were searched for publications from 2010 to March 2025. Eligible studies included empirical research and reviews examining (i) social media platforms, (ii) influencers, celebrities, or digital opinion leaders, and/or (iii) online communities or mobile and social applications used for blood donor recruitment or retention. Data were charted on study design, setting, digital platform, target population, intervention characteristics, and donor-related outcomes, and synthesised narratively. Evidence from broader eHealth and communication-intervention reviews was incorporated to contextualise social media within wider digital donor ecosystems.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;div&gt;The body of evidence has expanded rapidly but remains methodologically and conceptually heterogeneous. Facebook's blood donation tools and associated engagement strategies were associated with modest yet consistent increases in total donations (approximately 4%) and first-time donations (around 19%) in multi-country quasi-experimental studies. Platforms such as WhatsApp, Twitter/X, and Instagram function primarily as “just-in-time” mobilisation channels, particularly in the Middle East and low- and middle-income countries, with high success in meeting urgent donation requests but limited longitudinal data on donor retention. Systematic reviews of eHealth interventions and mobile applications suggest that digital tools, including apps, SMS, and social media, can improve donation and repeat behaviour when interventions are personalised, interactive, and integrated into service workflows. Emerging literature highlights donors as digital advocates and explores how online communities foster donor identity, peer norms, and advocacy. In contrast, ","PeriodicalId":23262,"journal":{"name":"Transfusion Clinique et Biologique","volume":"33 2","pages":"Pages 113-122"},"PeriodicalIF":1.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147380443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Practice variability in the evaluation and management of HLA alloimmunization in platelet refractoriness: a multi-institutional survey in the USA","authors":"Yigit Baykara ,&nbsp;Deanna C. Fang ,&nbsp;Minh-Ha Tran ,&nbsp;Muharrem Yunce","doi":"10.1016/j.tracli.2026.01.009","DOIUrl":"10.1016/j.tracli.2026.01.009","url":null,"abstract":"<div><h3>Background</h3><div>Platelet refractoriness is a frequent and challenging problem in thrombocytopenic patients who require long-term platelet transfusions. However, real-world practice in diagnosing and managing refractoriness remains variable with no inclusive guidelines. This study aimed to address this variability by means of conducting a survey.</div></div><div><h3>Methods</h3><div>We conducted an anonymous, web-based survey of U.S. hematology and oncology practitioners in 2024–2025 to capture current approaches to platelet refractoriness. The 20-item survey explored diagnostic thresholds, use of HLA antibody testing, application of calculated panel reactive antibody (cPRA) in clinical decision-making, strategies for selecting specialty platelets, and platelet transfusion thresholds across clinical scenarios. Responses were analyzed descriptively.</div></div><div><h3>Results</h3><div>28 practitioners responded, most of whom were attending hematologists at academic centers. Awareness of the technical platform for HLA antibody testing was limited, with nearly 90% of respondents unable to identify the assay used at their center. Few institutions reported a defined cPRA threshold to trigger specialized platelet support. For prophylaxis, most adhered to a 10 × 10³/µL threshold in inpatients, while outpatient thresholds varied more widely.</div></div><div><h3>Conclusions</h3><div>This national survey highlights marked heterogeneity in the recognition and management of platelet refractoriness among hematology and oncology practitioners. Development of targeted guidelines addressing immune-mediated refractoriness could help standardize practice and optimize patient care.</div></div>","PeriodicalId":23262,"journal":{"name":"Transfusion Clinique et Biologique","volume":"33 2","pages":"Pages 79-83"},"PeriodicalIF":1.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146095464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"“Catch them young”: an elementary idea to sculpt a generation of superheroes","authors":"Aswin K. Mohan,&nbsp;R. Arun,&nbsp;U.B. Davood","doi":"10.1016/j.tracli.2026.01.005","DOIUrl":"10.1016/j.tracli.2026.01.005","url":null,"abstract":"","PeriodicalId":23262,"journal":{"name":"Transfusion Clinique et Biologique","volume":"33 2","pages":"Pages 136-137"},"PeriodicalIF":1.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145986134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quality of life in patients with transfusion-dependent hemoglobinopathies: evidence from an expert centre in Greece","authors":"Sophia Delicou ,&nbsp;Aikaterini Xydaki ,&nbsp;Maria Moraki ,&nbsp;Natalia Karantzanou ,&nbsp;Clive Richardson ,&nbsp;Constantina Politis","doi":"10.1016/j.tracli.2026.01.008","DOIUrl":"10.1016/j.tracli.2026.01.008","url":null,"abstract":"<div><h3>Background</h3><div>Adults with hemoglobinopathies require lifelong transfusion support and long-term monitoring, which may substantially affect daily life and treatment burden. Data describing patient-reported transfusion practices in Greece remain limited.</div></div><div><h3>Objectives</h3><div>To describe transfusion practices, chelation therapy, monitoring patterns, and patient-reported daily life impact among Greek adults with hemoglobinopathies.</div></div><div><h3>Methods</h3><div>A cross-sectional anonymous online survey was distributed to adults (≥18 years) with self-reported hemoglobinopathies living in Greece. The questionnaire collected data on demographics, disease category, transfusion frequency, chelation therapy, monitoring practices, complications, and patient-reported impact on daily life. Analyses were descriptive.</div></div><div><h3>Results</h3><div>Transfusion practices and chelation therapy among participants are summarized in Table 1. A total of 114 respondents (mean age 49.4 ± 9.6 years; 53.5% female) completed the survey. Most participants reported regular transfusion therapy, commonly at intervals of ≤15 days, with variable transfusion volumes per session. Chelation therapy was widely reported, although adherence varied. Monitoring practices, including imaging for iron overload, were inconsistently reported. Participants described substantial treatment-related burden, including frequent healthcare visits and concerns regarding blood availability.</div></div><div><h3>Conclusions</h3><div>Greek adults with hemoglobinopathies report considerable transfusion-related treatment burden affecting daily life. These findings support the need for structured follow-up pathways and patient-centered care strategies.</div></div>","PeriodicalId":23262,"journal":{"name":"Transfusion Clinique et Biologique","volume":"33 2","pages":"Pages 76-78"},"PeriodicalIF":1.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146095466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mythic Origins of a Medical Milestone: Revisiting the Story of Blood Transfusion","authors":"Wassim Hamadeh ,&nbsp;Antoine Haddad ,&nbsp;Olivier Garraud","doi":"10.1016/j.tracli.2026.02.002","DOIUrl":"10.1016/j.tracli.2026.02.002","url":null,"abstract":"<div><div>Although transfusion medicine is a relatively recent addition to everyday clinical practice, the current understanding of blood as a therapeutic compound does not solely result from a single century of research, but rather from the culmination of millennia of observations, experimentations and interpretations. Early conceptions about blood have largely been transmitted through myths and mythology where blood is deeply connected to themes such as strength, power, life, heritage, wellbeing, holiness, suffering and death. Interestingly, this perception appears to be universal, transcending geographical and cultural boundaries. Most medical textbooks overlook this aspect which is crucial because these symbols and archetypes acted as a cultural substratum from which the modern understanding of transfusion gradually emerged, thereby carrying with it emotional and symbolic forces that still today shape the patient’s experience and perception of blood transfusion.</div><div>This review article traces the origins of transfusion medicine back to its most ancient foundations. It examines how early civilizations perceived blood, the symbols associated with it, how these ideas have influenced modern science thereby transforming ancestral beliefs associated with blood into a scientifically grounded medical practice. Tracing and recognizing this intellectual lineage underscore that medicine is not isolated from culture. Itconverts blood transfusion from a purely technical act into a humanistic gesture and provide physicians with deeper understanding why certain taboos, fears, or ethical debates persists around blood transfusion and help them to better empathize with patients who may have cultural or religious concerns about transfusion.</div></div>","PeriodicalId":23262,"journal":{"name":"Transfusion Clinique et Biologique","volume":"33 2","pages":"Pages 106-112"},"PeriodicalIF":1.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146184031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rethinking prompts, reimagining conclusions: Key elements for future large language model-based transfusion medicine education studies","authors":"K.M. Aswin,&nbsp;R. Arun,&nbsp;U.B. Davood","doi":"10.1016/j.tracli.2026.02.006","DOIUrl":"10.1016/j.tracli.2026.02.006","url":null,"abstract":"","PeriodicalId":23262,"journal":{"name":"Transfusion Clinique et Biologique","volume":"33 2","pages":"Pages 142-143"},"PeriodicalIF":1.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147370855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}