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Toxicological European research. Recherche europeenne en toxicologie最新文献

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[Effects of irradiated wheat flour in the AKR mouse. I. Effects on longevity, morbidity and pathology]. 辐照小麦粉对AKR小鼠的影响。1 .对寿命、发病率和病理的影响]。
Toxicological European research. Recherche europeenne en toxicologie Pub Date : 1983-01-01
M P Delcour-Firquet
{"title":"[Effects of irradiated wheat flour in the AKR mouse. I. Effects on longevity, morbidity and pathology].","authors":"M P Delcour-Firquet","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Mouse of AKR strain were fed with wheat flour irradiated at 75.000 rads or with nonirradiated flour during their lifetime. In this first part were analyzed : bodyweight, morbidity, mortality, organ's histology. Were established : higher bodyweight in all animals fed with irradiated flour, this increase is statistically significant only in males and a longer time life in all animals of this group, this last difference is significant in females and in animals together without distinction of sex.</p>","PeriodicalId":23153,"journal":{"name":"Toxicological European research. Recherche europeenne en toxicologie","volume":"5 1","pages":"7-15"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17906689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Effects of irradiated wheat flour in the AKR mouse. II. Effects on hematology and activity of a serum enzyme]. 辐照小麦粉对AKR小鼠的影响。2对血液学和血清酶活性的影响]。
Toxicological European research. Recherche europeenne en toxicologie Pub Date : 1983-01-01
M P Delcour-Firquet, P Bruaux
{"title":"[Effects of irradiated wheat flour in the AKR mouse. II. Effects on hematology and activity of a serum enzyme].","authors":"M P Delcour-Firquet,&nbsp;P Bruaux","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Blood samples were collected all six weeks from the tip of the tail of AKR mice fed with irradiated or non irradiated wheat flour. Haematocrit, red and white blood cell counts and differential white cell counts were determined and the activity of p-phenylenediamine oxidase was measured in the serum. No effect attributed to the diet could be demonstrated. We propose a method to detect antemortem the appearance of the AKR leukemia.</p>","PeriodicalId":23153,"journal":{"name":"Toxicological European research. Recherche europeenne en toxicologie","volume":"5 1","pages":"17-21"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17906686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Effects of irradiated wheat flour in the AKR mouse. IV. Effects on reproduction]. 辐照小麦粉对AKR小鼠的影响。对生殖的影响]。
Toxicological European research. Recherche europeenne en toxicologie Pub Date : 1983-01-01
M P Delcour-Firquet
{"title":"[Effects of irradiated wheat flour in the AKR mouse. IV. Effects on reproduction].","authors":"M P Delcour-Firquet","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Mouse of AKR strain received in their diet, 50% of wheat flour irradiated at 75000 rads or 50% of non irradiated flour during their lifetime. In this part, were analyzed data obtained through 7 consecutive mating : size of litters, weight and growth of pups, lethality in the first days, number of still-born, sex ratio. It was any significant difference between the two groups although many data were better in the test group.</p>","PeriodicalId":23153,"journal":{"name":"Toxicological European research. Recherche europeenne en toxicologie","volume":"5 1","pages":"27-30"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17906687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Experimental cadmium poisoning]. [实验性镉中毒]。
Toxicological European research. Recherche europeenne en toxicologie Pub Date : 1982-11-01
R Truhaut, N Phu-Lich, G Siou
{"title":"[Experimental cadmium poisoning].","authors":"R Truhaut,&nbsp;N Phu-Lich,&nbsp;G Siou","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>During the past years, many publications and reviews have described kidney and bone lesions observed after human chronic cadmium poisonings of food or occupational origin. In this experiment carried out in rat fed with normal diets or polydeprived of vitamin D3, calcium and proteins, with or without addition of cadmium, the bone lesions observed are as severe in all polydeprived animals, wether treated with cadmium or not.</p>","PeriodicalId":23153,"journal":{"name":"Toxicological European research. Recherche europeenne en toxicologie","volume":"4 6","pages":"291-6"},"PeriodicalIF":0.0,"publicationDate":"1982-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18186067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Effect of temephos on the acetylcholinesterase activity of the brain of Tilapia guineensis. 2: Experimental study of 24-hour exposure to the toxic compound]. 双硫磷对几内亚罗非鱼脑乙酰胆碱酯酶活性的影响。[2] 24小时暴露于有毒化合物的实验研究。
Toxicological European research. Recherche europeenne en toxicologie Pub Date : 1982-11-01
C Pelissier, D L Tack, G Gras
{"title":"[Effect of temephos on the acetylcholinesterase activity of the brain of Tilapia guineensis. 2: Experimental study of 24-hour exposure to the toxic compound].","authors":"C Pelissier,&nbsp;D L Tack,&nbsp;G Gras","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The exposition of the Tilapia guineensis to concentrations used in the field to destroy the simulium larvae in their aquatic biotopes is 0,05 mg/l/10 minutes. The authors have previously remarked a significant lowering of acetylcholinesterasic brain activity in this fish. In the case of a much prolonged contact (24h corresponding 144 times the theoretic time of contact), it is noticed that, if this immediate effect is not more pronounced, on the other hand it is noticeable for a much longer acetylcholinesterasic activity extends beyond forty days. In the same conditions, three successive weekly treatments lead the acetylcholinesterasic activity to the level of vital activity.</p>","PeriodicalId":23153,"journal":{"name":"Toxicological European research. Recherche europeenne en toxicologie","volume":"4 6","pages":"309-14"},"PeriodicalIF":0.0,"publicationDate":"1982-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17254402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Changes in the lysosomes and mitochondria isolated from the liver, kidney and heart of rats treated with perhexiline maleate. 马来酸过己胺对大鼠肝脏、肾脏和心脏溶酶体和线粒体的影响。
Toxicological European research. Recherche europeenne en toxicologie Pub Date : 1982-11-01
J P Bendirdjian, G Viotte, M Bichara, B Foucher, J P Fillastre
{"title":"Changes in the lysosomes and mitochondria isolated from the liver, kidney and heart of rats treated with perhexiline maleate.","authors":"J P Bendirdjian,&nbsp;G Viotte,&nbsp;M Bichara,&nbsp;B Foucher,&nbsp;J P Fillastre","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A seven-days treatment, with Perhexilline Maleate induces changes in the structural latency of lysosomes isolated from liver or kidney and of the respiratory activity of mitochondria isolated from liver, kidney or heart. While the effect on lysosomal structural latency appears very similar in the liver and kidney lysosomes, the oxidative properties of liver mitochondria appears clearly more disturbed than those of the heart or kidney. It is concluded that liver mitochondria might be strongly involved in the mechanism of Perhexiline Maleate hepatotoxicity.</p>","PeriodicalId":23153,"journal":{"name":"Toxicological European research. Recherche europeenne en toxicologie","volume":"4 6","pages":"297-300"},"PeriodicalIF":0.0,"publicationDate":"1982-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18186068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Precision and accuracy of a radioimmunoassay versus GLC procedure for quantitative determination of morphine compounds in biological materials. 放射免疫测定法与GLC法定量测定生物材料中吗啡化合物的精密度和准确性。
Toxicological European research. Recherche europeenne en toxicologie Pub Date : 1982-11-01
F de Ferrari, V Gambaro, F Lodi, E Marozzi, E Saligari
{"title":"Precision and accuracy of a radioimmunoassay versus GLC procedure for quantitative determination of morphine compounds in biological materials.","authors":"F de Ferrari,&nbsp;V Gambaro,&nbsp;F Lodi,&nbsp;E Marozzi,&nbsp;E Saligari","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The authors, using GLC and RIA, have measured morphine in post-mortem biological material obtained from subjects died for heroin intoxication. Statistical analysis of the two sets of data indicated a high and satisfactory correlation. Recognizing the RIA was a more rapid and simple procedure the authors decide to study the recovery of morphine for various biological materials as determined by RIA. The results demonstrated that the initial concentration of morphine in the various organs did not affect the assay results, but the concentration in assay tubes was important. At concentrations between 10 and 40 ng/ml the recovery was excellent, with no important differences between the organs. It was concluded that the radioimmunological assay can be validly used in forensic medicine to measure morphine in biological materials.</p>","PeriodicalId":23153,"journal":{"name":"Toxicological European research. Recherche europeenne en toxicologie","volume":"4 6","pages":"315-9"},"PeriodicalIF":0.0,"publicationDate":"1982-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18186069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[A case of occupational benzene poisoning combined with tricholeukocytic leukemia]. [职业性苯中毒合并白细胞白血病1例]。
Toxicological European research. Recherche europeenne en toxicologie Pub Date : 1982-11-01
J Bescol-Liversac, C Chabaux, S Bolinard, C Guillam
{"title":"[A case of occupational benzene poisoning combined with tricholeukocytic leukemia].","authors":"J Bescol-Liversac,&nbsp;C Chabaux,&nbsp;S Bolinard,&nbsp;C Guillam","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Case report of occupational intoxication, with moderate anemia and hypogranulocytosis, in the course of which occurs a hairy cell leukemia. Cytological data are significative in photonic and electronic microscopy: microvilli and granulo-lamellar complexes. Discussion of benzen, as toxic factor in etiology of this leukemia.</p>","PeriodicalId":23153,"journal":{"name":"Toxicological European research. Recherche europeenne en toxicologie","volume":"4 6","pages":"329-35"},"PeriodicalIF":0.0,"publicationDate":"1982-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18186071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Marine ecotoxicology and heavy metals in the Mediterranean sea]. [海洋生态毒理学与地中海重金属]。
Toxicological European research. Recherche europeenne en toxicologie Pub Date : 1982-11-01
M Aubert
{"title":"[Marine ecotoxicology and heavy metals in the Mediterranean sea].","authors":"M Aubert","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Marine ecotoxicology has been developed by the acquisition of new methods of measurements. Among them, \"in vitro\" biological marine chains allow the evaluation of the risks for the environment and the public health. The study of the heavy metals in the Mediterranean atmosphere, seawater and fauna allows the evaluation of their pollution and the detection of its origin. The comparison of the \"in situ\" measurements with those of the \"in vitro\" trophic models shows the interest of the methodology.</p>","PeriodicalId":23153,"journal":{"name":"Toxicological European research. Recherche europeenne en toxicologie","volume":"4 6","pages":"321-8"},"PeriodicalIF":0.0,"publicationDate":"1982-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18186070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Effect of temephos on the acetylcholinesterase activity of the brain of Tilapia guineensis. 1: Experimental study at operative doses]. 双硫磷对几内亚罗非鱼脑乙酰胆碱酯酶活性的影响。[1]手术剂量的实验研究。
Toxicological European research. Recherche europeenne en toxicologie Pub Date : 1982-11-01
G Gras, C Pelissier, D L Tack
{"title":"[Effect of temephos on the acetylcholinesterase activity of the brain of Tilapia guineensis. 1: Experimental study at operative doses].","authors":"G Gras,&nbsp;C Pelissier,&nbsp;D L Tack","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>After having exposed during 10 minutes the Tilapia guineensis to a concentration of 0,05 mg/l of temephos (concentration of a larvicide used for the field test), the authors note a lowering of the acetylcholinesterastic activity of the brain to an order of 25%. The return to a normal activity is achieved within 20 to 25 days. A new exposure, happening one week after the first, provokes a further lowering before the return to a normal value. The authors question themselves on the consequences of these chemical attacks repeated on a weekly basis during antilarval treatments in the struggle against the onchocercose.</p>","PeriodicalId":23153,"journal":{"name":"Toxicological European research. Recherche europeenne en toxicologie","volume":"4 6","pages":"301-8"},"PeriodicalIF":0.0,"publicationDate":"1982-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17254401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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