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Systematic review on the adverse reactions of oral administration of Indigo Naturalis and its preparations 青黛及其制剂口服不良反应的系统评价
TMR Modern Herbal Medicine Pub Date : 2021-01-01 DOI: 10.53388/mhm2021b0117001
Xueyi Deng, Ruirui Lan, Qianwen Xie, Jingmin Xiao, Jiaqi Lai, Jing Chen, Yihan He, Shaonan Liu, Lihong Yang, Xin-feng Guo
{"title":"Systematic review on the adverse reactions of oral administration of Indigo Naturalis and its preparations","authors":"Xueyi Deng, Ruirui Lan, Qianwen Xie, Jingmin Xiao, Jiaqi Lai, Jing Chen, Yihan He, Shaonan Liu, Lihong Yang, Xin-feng Guo","doi":"10.53388/mhm2021b0117001","DOIUrl":"https://doi.org/10.53388/mhm2021b0117001","url":null,"abstract":"","PeriodicalId":23141,"journal":{"name":"TMR Modern Herbal Medicine","volume":"71 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75391009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
JSON-ASR: A lightweight data storage and exchange format for automatic systematic reviews of TCM JSON-ASR:用于中医自动系统评审的轻量级数据存储和交换格式
TMR Modern Herbal Medicine Pub Date : 2021-01-01 DOI: 10.53388/mhm2021a0401001
Ji Xu, Hongyong Deng
{"title":"JSON-ASR: A lightweight data storage and exchange format for automatic systematic reviews of TCM","authors":"Ji Xu, Hongyong Deng","doi":"10.53388/mhm2021a0401001","DOIUrl":"https://doi.org/10.53388/mhm2021a0401001","url":null,"abstract":"","PeriodicalId":23141,"journal":{"name":"TMR Modern Herbal Medicine","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88291193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The clinical efficacy of traditional Chinese medicine in the auxiliary treatment of grade 1 hypertension: A systematic review and meta-analysis 中药辅助治疗1级高血压的临床疗效:系统综述和meta分析
TMR Modern Herbal Medicine Pub Date : 2021-01-01 DOI: 10.53388/mhm2021a1008002
Jinghan Wang, Zhen Hua, Chao Li, Yun-Li Li
{"title":"The clinical efficacy of traditional Chinese medicine in the auxiliary treatment of grade 1 hypertension: A systematic review and meta-analysis","authors":"Jinghan Wang, Zhen Hua, Chao Li, Yun-Li Li","doi":"10.53388/mhm2021a1008002","DOIUrl":"https://doi.org/10.53388/mhm2021a1008002","url":null,"abstract":"","PeriodicalId":23141,"journal":{"name":"TMR Modern Herbal Medicine","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87918408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Research of the clinical efficacy of Qiming Granule in treatment of diabetic nephropathy by meta-analysis 芪明颗粒治疗糖尿病肾病临床疗效的meta分析研究
TMR Modern Herbal Medicine Pub Date : 2021-01-01 DOI: 10.53388/mhm2021m0305001
Ning Liu, Tao He, Chuanxin Liu, Jianmei Huang
{"title":"Research of the clinical efficacy of Qiming Granule in treatment of diabetic nephropathy by meta-analysis","authors":"Ning Liu, Tao He, Chuanxin Liu, Jianmei Huang","doi":"10.53388/mhm2021m0305001","DOIUrl":"https://doi.org/10.53388/mhm2021m0305001","url":null,"abstract":"","PeriodicalId":23141,"journal":{"name":"TMR Modern Herbal Medicine","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76936105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Progress of ubiquitin-proteasome system in the pathophysiology of heart failure and the intervention of traditional Chinese medicine 泛素-蛋白酶体系统在心力衰竭病理生理中的研究进展及中药干预
TMR Modern Herbal Medicine Pub Date : 2021-01-01 DOI: 10.53388/mhm2021b0420001
Jie Chen, Xiaohong Wei, Qian Zhang, Huan Xia, Guiyang Xia, Yuzhuo Wu, Sheng Lin, H. Shang
{"title":"Progress of ubiquitin-proteasome system in the pathophysiology of heart failure and the intervention of traditional Chinese medicine","authors":"Jie Chen, Xiaohong Wei, Qian Zhang, Huan Xia, Guiyang Xia, Yuzhuo Wu, Sheng Lin, H. Shang","doi":"10.53388/mhm2021b0420001","DOIUrl":"https://doi.org/10.53388/mhm2021b0420001","url":null,"abstract":"","PeriodicalId":23141,"journal":{"name":"TMR Modern Herbal Medicine","volume":"44 7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75681142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
The therapeutic efficiency of ursodeoxycholic acid on Gilbert syndrome complicated by aplastic anemia: a series of case reports 熊去氧胆酸治疗吉尔伯特综合征合并再生障碍性贫血的疗效观察
TMR Modern Herbal Medicine Pub Date : 2021-01-01 DOI: 10.53388/mhm2020c1106001
Yanyu Zhang, X. Cui, Jie Xu
{"title":"The therapeutic efficiency of ursodeoxycholic acid on Gilbert syndrome complicated by aplastic anemia: a series of case reports","authors":"Yanyu Zhang, X. Cui, Jie Xu","doi":"10.53388/mhm2020c1106001","DOIUrl":"https://doi.org/10.53388/mhm2020c1106001","url":null,"abstract":"","PeriodicalId":23141,"journal":{"name":"TMR Modern Herbal Medicine","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90578317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Auricular Vagus Nerve Acupressure for Patients with Emotional Distress under the COVID-19 Pandemic: A Smartphone-based, Randomized，Controlled Trial (Preprint) 基于智能手机的耳迷走神经指压治疗新冠肺炎大流行下情绪困扰患者的随机对照试验(预印本)
TMR Modern Herbal Medicine Pub Date : 2020-10-15 DOI: 10.2196/preprints.25001
P. Rong, Lei Wang, Lingling Yu, Junying Wang, Yanzhen Ma, Liting Wang, Suxia Li, Chun-lin Tang, Liming Lu, Liang Li, Jiazi Dong, J. Fang, Liwei Hou, Zongshi Qin, Xiao-lan Su, Yufeng Zhao, Zhangjin Zhang
{"title":"Auricular Vagus Nerve Acupressure for Patients with Emotional Distress under the COVID-19 Pandemic: A Smartphone-based, Randomized，Controlled Trial (Preprint)","authors":"P. Rong, Lei Wang, Lingling Yu, Junying Wang, Yanzhen Ma, Liting Wang, Suxia Li, Chun-lin Tang, Liming Lu, Liang Li, Jiazi Dong, J. Fang, Liwei Hou, Zongshi Qin, Xiao-lan Su, Yufeng Zhao, Zhangjin Zhang","doi":"10.2196/preprints.25001","DOIUrl":"https://doi.org/10.2196/preprints.25001","url":null,"abstract":"\u0000 BACKGROUND\u0000 The global spread of the 2019 coronavirus diseases (COVID-19) has caused emotional distress. However, whether auricular vagus nerve acupressure (AVNA) is effective in improving emotional distress under the COVID-19 has not been well-documented.\u0000 \u0000 \u0000 OBJECTIVE\u0000 To confirm whether AVNA is effective in improving emotional distress under the COVID-19 pandemic.\u0000 \u0000 \u0000 METHODS\u0000 A smartphone-based online, randomized, controlled trial was designed in four study sites, including Wuhan, Beijing, Shenyang, and Guangzhou of China, from 26 February 2020 to 28 April 2020. Participants were randomly assigned to three times of AVNA (n = 191) or usual care (UC, n = 215) for 14 days. The primary outcome was the response rate, which was the proportion of participants whose Hospital Anxiety and Depression Scale (HADS) score reduced from baseline by ≥ 50%. The assessment was conducted at baseline, 3 days, and 14 days.\u0000 \u0000 \u0000 RESULTS\u0000 The AVNA group had a markedly higher response rate than the UC group at 3 days (35.6% vs. 24.9%, P = 0.02) and at 14 days (70.7% vs. 60.6%, P = 0.02). The AVNA group showed significantly greater reduction in score of HADS at the two measurement points and BAI at 3 days (P ≤ 0.03), with average respective effect size of 0.217 and 0.195. Participants with AVNA spent less time falling asleep and rated their sleep quality being remarkably higher than those with UC at endpoint.\u0000 \u0000 \u0000 CONCLUSIONS\u0000 AVNA can be recommended for patients with emotional distress under the current COVID-19 pandemic and other emergent events.\u0000 \u0000 \u0000 CLINICALTRIAL\u0000 www.chictr.org.cn Identifier: ChiCTR2000030078.\u0000","PeriodicalId":23141,"journal":{"name":"TMR Modern Herbal Medicine","volume":"27 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85728953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Niaoduqing Granules Inhibits TGF-β1-induced Epithelial-Mesenchymal Transition in Human Renal Tubular Epithelial HK-2 Cells 尿毒清颗粒抑制TGF-β1诱导的人肾小管上皮HK-2细胞上皮间质转化
TMR Modern Herbal Medicine Pub Date : 2020-06-12 DOI: 10.21203/rs.3.rs-34640/v1
Chuying Huo, Huayi Yang, W. Ning, Lin-zhong Yu, Chunlin Fan, Jingyu Quan, L. Deng, Zhi-Ling Yu, Junshan Liu, Huihui Cao
{"title":"Niaoduqing Granules Inhibits TGF-β1-induced Epithelial-Mesenchymal Transition in Human Renal Tubular Epithelial HK-2 Cells","authors":"Chuying Huo, Huayi Yang, W. Ning, Lin-zhong Yu, Chunlin Fan, Jingyu Quan, L. Deng, Zhi-Ling Yu, Junshan Liu, Huihui Cao","doi":"10.21203/rs.3.rs-34640/v1","DOIUrl":"https://doi.org/10.21203/rs.3.rs-34640/v1","url":null,"abstract":"\u0000 Background: Chronic renal failure (CRF) is a worldwide public health burden. Niaoduqing granules (NDQ) is widely used for CRF treatment in China. However, the underlying mechanism of NDQ is not fully studied. This study is aimed to investigate whether NDQ ameliorate CRF by inhibiting TGF-β1-induced EMT in human renal tubular epithelial HK-2 cells.Methods: MTT assay and colony formation assay were used to investigate the cytotoxicity of NDQ in HK-2 cells. Morphological changes of HK-2 cells after TGF-β1 or/and NDQ treatment were observed under a microscope. Wound-healing, migration and invasion assays were performed to determine the cell movement, migratory and invasive abilities, respectively. Western blot analysis was carried out to examine the protein levels of TGF-β type I receptor (TβRI) and EMT-associated factors. Fluorescence confocal microscopy was applied to observe the organization of F-actin.Results: NDQ suppressed TβRI expression dose-dependently. NDQ inhibited TGF-β1-stimulated EMT in HK-2 cells, supported by the evidences that NDQ prevented morphology change, attenuated cell migration and invasion, downregulated EMT factors and reorganized F-actin distribution in TGF-β1-stimulated HK-2 cells.Conclusions: NDQ attenuates chronic renal failure which may be associated with inhibition of TβRI expression and EMT process.","PeriodicalId":23141,"journal":{"name":"TMR Modern Herbal Medicine","volume":"41 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77748159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of theophylline/chitosan/β-cyclodextrin microspheres for oral drug delivery on an asthmatic rat model 茶碱/壳聚糖/β-环糊精微球口服给药对哮喘大鼠模型的影响
TMR Modern Herbal Medicine Pub Date : 2020-05-01 DOI: 10.12032/TMRMHM202003071
Saisai Wang, Haijing Zhang, Xiaoming Cui, Liping Zhao, Mingxia Jiang, Zhilu Xu, Dong-zhen Mu, Weifen Zhang
{"title":"Effects of theophylline/chitosan/β-cyclodextrin microspheres for oral drug delivery on an asthmatic rat model","authors":"Saisai Wang, Haijing Zhang, Xiaoming Cui, Liping Zhao, Mingxia Jiang, Zhilu Xu, Dong-zhen Mu, Weifen Zhang","doi":"10.12032/TMRMHM202003071","DOIUrl":"https://doi.org/10.12032/TMRMHM202003071","url":null,"abstract":"","PeriodicalId":23141,"journal":{"name":"TMR Modern Herbal Medicine","volume":"21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75477742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The roles of traditional Chinese herbal medications in regulating mitochondrial activity to reverse cancer 中药在调节线粒体活性以逆转癌症中的作用
TMR Modern Herbal Medicine Pub Date : 2020-05-01 DOI: 10.12032/TMRMHM202003076
Lichao Sun, Guihua Tian, H. Shang
{"title":"The roles of traditional Chinese herbal medications in regulating mitochondrial activity to reverse cancer","authors":"Lichao Sun, Guihua Tian, H. Shang","doi":"10.12032/TMRMHM202003076","DOIUrl":"https://doi.org/10.12032/TMRMHM202003076","url":null,"abstract":"","PeriodicalId":23141,"journal":{"name":"TMR Modern Herbal Medicine","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88617943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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